Claim OwnershipTough Tech Today with Meyen and Miller
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© 2024 Tough Tech Today, by Jonathan Miller and Forrest Meyen
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This is the premiere show featuring trailblazers who are building technologies today to solve tomorrow's toughest challenges.
32 Episodes
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Where is the money in oceanographic research? Fundamental understanding of the watery parts of our planet (i.e. most of it) is woefully under pursued. However, just as it seems some ocean systems are almost falling apart – coral bleaching, rising tides, species extinctions – we are beginning to see more attention paid to exploring the depths. "There will be unicorns of the ocean, very successful companies which we call ‘narwhals’,” Adam de Sala Pool told us. A Special Advisor to the Woods Hol...
It’s a bird, it’s a plane, it’s… technically a flying boat! When challenged to imagine how to electrify aviation, Billy Thalheimer, CEO and co-founder of REGENT Craft, and his team set to work looking at what has been done with hydroplanes before – and what emerging technologies are available today that change the equation for what is possible and economically achievable.“Building with atoms is harder than building with bits. You can’t just revert to your last code push,” Mr. Thalheimer ...
The blue parts of our planet are beautiful yet stunningly punishing for even our toughest of technologies.Dark, crushing, unexplored, and unknown – the depths of the seas are where an explorer like Jeff Smith has devoted his career to understanding. As the Vice President and General Manager of Autonomous and Undersea Systems at Saab, Inc., Smith has experience developing submersibles of nearly every shape and size, including some of the most advanced systems for remotely-operated and autonomo...
Tough Tech Today is transitioning seasons, recapping our Season 3 themes exploring the tough tech domains of biology, space, and fusion energy. We are also preparing for the show's fourth season and we are really excited for it!Upcoming themes:Blue tech – The advanced technologies of the maritime industry. Incredible machines, sustainable oceans, and mysteries to solve in our planet's seas.Quantum sciences – A wild world where physics gets weird, we are super curious about opportunities in co...
If this company perfectly combines lasers and atoms, the reaction could be worth trillions of dollars.Focused Energy’s Thomas Forner, CEO, and Pravesh Patel, CTO, join us to talk about making lasers. Lots and lots of lasers. But for what aim? They are pointing hundreds of directed beams at a tiny target: a millimeter-sized plastic capsule of deuterium and tritium, about the size of a peppercorn. These experiments may reveal a commercial pathway to grid-scale fusion energy. In contrast to othe...
Investors are betting big on clean energy becoming the norm.Tina Tosukhowong of TDK Ventures joins us for a review of the major approaches to curbing carbon emissions in hard-to-abate industries. A thorough assessment led Tosukhowong to opportunities for practical, grid-scale fusion. TDK Ventures invested in Type One Energy Group, a private fusion company affiliated with the University of Wisconsin-Madison. Their stellarator-based design is one of several that have emerged in recent years, wi...
How do we harness the power of the stars to deliver clean energy on Earth?It has been a collective goal – and, perhaps, an impending imperative – for human civilization to secure renewable energy sources for its present and future needs. The team at Proxima Fusion (https://www.proximafusion.com/about), led by co-founder and CEO Francesco Sciortino (https://www.linkedin.com/in/francesco-sciortino-aa340180/), is focused on one approach to build a fusion power plant. Their use of a “stellarator”...
Standing up a space force within the world’s largest bureaucracy is not for the faint of heart.Preston Dunlap – former (and first) Chief Architect / Chief Technology Officer of the United States Air Force and Space Force and present CEO of Arkenstone Ventures – has developed a privileged view into the government machinations necessary to design, develop, and buy the right mix of tough tech capabilities. Mission-focused and multidisciplinary, Dunlap and the organizations in which he engaged at...
An early-stage startup will offer unparalleled weather data when it unfolds its orbital sensors.Captivated by the stars and focused on improving life on Earth, Mithril Technologies founder and CEO, Scarlett Koller, is venturing into weather awareness and storm tracking by launching and commercializing a large space-based sensor. In this episode, we have the privilege of learning how Koller and her co-founder are translating a new technology out of the lab and into a space business.Aviation, s...
In one sentence: The space economy is booming in more ways than one.Space-based assets are changing the way industries operate on Earth. Chad Anderson – Founder and Managing Partner at Space Capital – is one of those individuals who has a deep perspective on the what it is like backing the entrepreneurs who are launching the newest breed of space companies.An investor by profession and explorer by passion, Anderson relates to us how “the economy of the future” will be built on global position...
In one sentence... The interactions of the microbial world within us has been incredibly difficult to see – until now.From the depths of our intestines to the surface of our skin, our bodies are host to trillions of microbial cells spanning thousands of species. While critical to helping us to fend off illnesses and digest complex foods, we know very little about the complex interactions among these microbes.The team at Concerto Biosciences, led by CEO and Cofounder Cheri Ackerman, has put in...
In one sentence...Aging is malleable and there is a particular, mysterious protein of interest that may enable new therapies for age-related diseases such as stroke, diabetes, and obesity.Young blood in old bodies has been demonstrated in several studies to counteract some age-correlated ailments. Mark Allen, a medical doctor by training and an entrepreneur in practice, co-founded Elevian to understand and commercialize therapies using a recombinant growth differentiation factor known as GDF1...
In one sentence...Computational biology is enhancing our understanding of intrinsically disordered proteins, leading to exciting new medical treatments.OverviewFrom videogames to protein discovery, high performance computing impacts how we understand and engage with each other and the world around us. Virginia Burger, CEO and Co-Founder of New Equilibrium Biosciences, epitomizes the value of interdisciplinary skills applied to a hunch that biology and computer modeling can lead to new medical...
Join a tag-up among JMill and Forrest as we reveal something really exciting for what’s ahead: the launch of the newest season of Tough Tech Today! Plus, we mention work and babies.We set the stage for our new monthly cadence, with a new release occurring on the second Tuesday of each month. Each quarter (3 months), we focus on a theme. The next three themes are Biology (2023Q2), Space (2023Q3), and Energy (2023Q4). We really appreciate your support and enthusiasm for Tough Tech Today, a...
Digitization of the physical world brings new synergies and expanding attack surfaces – so it is key to invest in those who defend us.—————Overview: Probing the cybersecurity of 3D printing, scaling the digital transformation of manufacturing, and developing quantum-safe encryption for the next evolution of the Internet, Matt Goldstein, Managing Director at M12, Microsoft’s Venture Fund, shares with us the criticality of investing in companies exploring the frontiers of cybersecurity and...
In one sentence: “Synthesizing” and “food” are uncommon word pairings, but the engineered dishes they serve may be an appetizing feast for the senses.Overview: Climate change, a growing global population, and maturation of new biotechnologies are driving the motivation for – and means of – producing more food. Engineering is improving traditional agricultural means for food production, yet, in our conversation with Kate Krueger of Helikon, emerging synthesization techniques are bringing food ...
In one sentence:We can make cancer cells tell us exactly where they are.—————Overview:Consumer internet entrepreneurs lack many of the skills for the life sciences revolution – or do they? Cyriac Roeding, CEO and co-founder of Earli, shows us what his team of bioengineers are accomplishing by applying fast-learning software development discipline to hard life science problems. Earli’s mouse and canine models are producing exciting results inducing cancer cells to expose their locations, enabl...
Just a quick Tough Tech Today update as we take a bye week and prepare for our guest in two weeks.
In one sentence: When the frontiers of geology overlap with the frontlines of contested regions, international collaborations help protect minerals core to our civilization.—————Overview:There’s a world of minerals in every electronic device. Anything that cannot be grown must be mined, Emily King tells us. A global mining expert and founder of Prospector Portal, Emily shares stories and advancements in the finding, protecting, and stewarding of minerals.From digitizing and structuring dispar...
In one sentence: Unlocking new mRNA treatments will save lives, but it's not as simple as that.—————Overview—————Jake Becraft of Strand Therapeutics is an expert in designing and programming mRNA, critical strands of genetic material that provide instructions for making proteins. As one suite of tools in the emerging synthetic biology toolkit, mRNA is a twenty-first century harbinger of life. Yet, with all powerful tools, there are risks of accidental or intentional misuse. It is this sh...
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