Understanding Animal Research

The larger the mammal, the longer it lives. Elephants live longer than mice. According to this theory naked mole-rats should live for two or three years. They can actually live for more than 30. One reason is that they almost never die from cancer. More from Dr Ewan St. John Smith here: https://www.understandinganimalresearch.org.uk/news/research-medical-benefits/the-secrets-of-the-naked-mole-rats/

Contact UAR at office@uar.org.uk if you would like to use this footage.

Dr Mark Dallas describes research into Alzheimer's using mice and cells.

Presentation part of zoom AGM 2021, no AGM votes

Dolly was the first cloned sheep. This is an explanation of how it was done. Read more here: https://www.understandinganimalresearch.org.uk/animals/areas-research/animal-cloning/ and https://www.animalresearch.info/en/medical-advances/medical-discovery-timeline/cloning-dolly-the-sheep/ Originally in a 2010 flash file format, this film was restored and uploaded in 2021.

More mice are used in scientific and medical research than all other types of animal combined. Caring for mice so that they are healthy and content is crucial for their sake, and for the sake of the science. Food and water is usually provided 'ad lib,' the mice can eat and drink as much as they want. The absorbent material at the bottom of the cage is cleaned out regularly, typically every week. Cages have chew sticks and cardboard tubes to hide in and chew. Rodent teeth keep growing so mice have to chew to wear them down. Nesting material is also added and in some places seeds and dried fruit are hidden in with the bottom wood-chips so that the mice are stimulated to explore and dig.

Ferrets, mice, chickens eggs, what do they have to do with making vaccines? And how do vaccines work anyway? If you are over 11, this film should show you.

Mouse in forced swim test, subtitles, for social media

Xenopus laevis B roll

What are viruses, what do they do to you and is there anything that can be done about them?

See http://www.understandinganimalresearch.org.uk/news/research-medical-benefits/animal-research-and-pregnancy-testing-a-history/

Spiders, scorpions and other venomous animals are 'milked' for their venom which is then used in medical research. These animal were filmed at Venomtech, a specialist venom supplier (https://venomtech.co.uk). Find out more about venom derived drugs here: http://www.animalresearch.info/en/drug-development/venom-derived-drugs/

Professor Dame Nancy Rothwell, President and Vice-Chancellor of the University of Manchester, gave the 2019 Paget Lecture. She presented her ground breaking work on stroke and the role of inflammation in brain damage, that has recently translated into clinical trials.

This year the Openness Awards celebrate four recipients that have met the Concordat commitments and encouraged the widespread sharing of best practice. These are the different categories: Internal or sector engagement activity: Newcastle University Public engagement activity: University of Edinburgh Media engagement or media stories: The Francis Crick Institute Website or use of new media: University of Reading Individual awards: Val Summers and Professor Nick Wells The Concordat on Openness launched in May 2014 and has, to date, brought together 122 organisations in a pledge to be more open and transparent about their use of animals in research.

Finding compounds active against cancer from venoms.

Researchers have found that laboratory mice moved by tail handling rather than by tunnel are less responsive to reward which has implications for designing and interpreting scientific studies. Here is the original research https://www.nature.com/articles/s41598-018-20716-3  and here is the original press release https://www.ncl.ac.uk/press/articles/archive/2018/02/mousehandling/

Researchers have found that laboratory mice moved by tail handling rather than by tunnel are less responsive to reward which has implications for designing and interpreting scientific studies. Here is the original research https://www.nature.com/articles/s41598-018-20716-3  and here is the original press release https://www.ncl.ac.uk/press/articles/archive/2018/02/mousehandling/