What's Your Problem?

After a historic 355 days in orbit, NASA astronaut Mark Vande Hei returned to Earth on March 30, 2022, breaking the record for the longest single spaceflight by an American. In this episode of Smart Talks with IBM, Malcolm Gladwell and Mark Vande Hei discuss conducting experiments in space, the impact of extended spaceflight on humans, and the spiciness of space chili peppers. This is a paid advertisement from IBM.See omnystudio.com/listener for privacy information.

Imagine picking up your phone and ordering something from Walmart. Fifteen minutes later, a drone hovers over your yard, lowers your order down to you, and zips away. Adam Woodworth wants this to be so boring you don't even notice. He’s the CEO of Wing, a drone delivery company. His problem is this: How do you turn a flashy idea like a delivery drone into something as ubiquitous as a shopping cart?See omnystudio.com/listener for privacy information.

Psychedelics are going mainstream. The FDA has approved ketamine for certain patients with depression, and may soon approve MDMA for post-traumatic stress disorder (PTSD). But a fundamental question remains unclear: How do psychedelics work? Gul Dolen is a professor of psychology and neuroscience at UC Berkeley. In a series of experiments, Gul has found evidence of a common mechanism that a wide range of psychedelics use to affect the brain. If Gul is correct, these drugs may be useful not only for people suffering from mental illness, but also for people dealing with neurological problems like strokes.See omnystudio.com/listener for privacy information.

Kai Marshland is the co-founder and chief product officer at WindBorne Systems. Kai's problem is this: How do you build weather balloons that can stay in the air for months at a time, and pair the data gathered by the balloons with AI to make weather forecasts that are way better than anything we have today?See omnystudio.com/listener for privacy information.

Jonathan Hurst is a professor at Oregon State University, and co-founder and chief robot officer at Agility Robotics. Jonathan's problem is this: How do you design a robot that can walk and do useful tasks that companies will pay for? The solution begins with trying to understand how birds walk.See omnystudio.com/listener for privacy information.

The 2008 Global Financial Crisis was hard for almost everyone. Fuquan Bilal remembers it like it was yesterday. A real estate investor, among other things, he came home to the news of the crash and the sharp realization that he lost $2 million overnight. That could have been the end with advisors telling him to file for bankruptcy.    Join Ben and Tanya as they chat with Fuquan about how he fought to keep his companies afloat. Discover how he brought his business back from the dead, ignoring common sense, for his own gut instincts, his investments to diversify his income, and back into better communities for all. These are The Unshakeables.      The Unshakeables is brought to you by Chase for Business and Ruby Studio by iHeartMediaSee omnystudio.com/listener for privacy information.

What does sickness sound like? Sometimes it’s obvious, like a cough, sniffle, or stuffy nose. But some conditions cause subtle changes that only a trained ear – or AI – can detect. Dr. Yael Bensoussan is a professor of otolaryngology and the director of the Health Voice Center at the University of South Florida. Her problem is this: How do you build a giant, public database of thousands of voice recordings, and use it to train AI tools that can hear when people are getting sick?See omnystudio.com/listener for privacy information.

Cement is, almost literally, everywhere. It is extraordinarily useful, which is why humanity makes 4 billion metric tons of it every year. But cement is also extremely carbon intensive to produce. Leah Ellis is the co-founder and CEO of Sublime Systems. Her problem is this: How can you make cement, at scale, without emitting carbon dioxide?See omnystudio.com/listener for privacy information.

Sam D'Amico is the founder and CEO of Impulse Labs, a company that makes induction stoves, with a clever twist. Sam’s problem is this: How do you build an electric cooktop that works just as well as gas, and can be installed without having to rewire the house? The solution that Sam found could eventually help transform not only kitchens, but the way homes draw power from the electrical grid. See omnystudio.com/listener for privacy information.

Tim Ellis is the co-founder and CEO of Relativity Space, a company with a unique approach to manufacturing rockets. Tim’s problem is this: How can you use 3D printing to make rockets more efficiently? Eventually, Tim wants to send a rocket – and printer – to Mars to build the first Martian industrial base. See omnystudio.com/listener for privacy information.

Every year in the U.S., tens of thousands of hospital patients die of preventable causes. For many of these patients, warning signs are subtle and easy for doctors to miss. Suchi Saria is the founder and CEO of Bayesian Health, and a professor at Johns Hopkins where she runs a lab focused on machine learning and healthcare. Suchi’s problem is this: How can you use AI to detect when hospital patients are at risk of potentially deadly complications – and how can you get doctors to listen?See omnystudio.com/listener for privacy information.

Gia Schneider is the co-founder and CEO of Natel Energy, a company that is trying to transform the way hydroelectric power works. Gia’s problem is this: how do you draw hydropower from rivers without damaging the ecosystem? As it turns out, we have a lot to learn from nature’s furriest engineers – beavers.See omnystudio.com/listener for privacy information.

Peter Chen is the co-founder and CEO of Covariant. Peter’s problem is this: How do you take the AI breakthroughs of the past decade or so, and make them work in robots? Peter was one of the first employees at OpenAI, the maker of ChatGPT. On the show, he talks about how AI has evolved, and why it's so difficult to teach a robot to fold a towel.See omnystudio.com/listener for privacy information.

Fei-Fei Li is a Stanford computer scientist and the former chief scientist of artificial intelligence/machine learning at Google Cloud. When Li entered the field of AI in the 2000s, researchers were making slow progress, optimizing algorithms to incrementally improve outcomes. Li saw that the problem wasn’t the algorithm, but the size of the datasets being used. So she built a massive database of images called ImageNet. It was a huge breakthrough, and helped lead the emergence of modern AI.See omnystudio.com/listener for privacy information.

Tim Latimer is the CEO and co-founder of Fervo Energy, a company that is using a new approach to produce carbon-free geothermal energy. Tim and his company are drawing on innovations from the oil and gas industry to expand geothermal energy production to new places like the Utah desert, and maybe one day, to Mars.See omnystudio.com/listener for privacy information.

Manolis Kellis is a professor of Computer Science at the Massachusetts Institute of Technology. He works in computational biology, taking giant datasets relating to genetics and health outcomes and tries to understand what’s going on. Manolis’ research focuses on genomics, and a related field called epigenomics. Manolis’ problem is this: What are the cellular mechanisms of a disease? And how can we intervene to keep people healthy?See omnystudio.com/listener for privacy information.

After working as a chef for decades, Anthony Strong’s dream came true: He opened his own restaurant. His problem was a classic one: Restaurants are bad businesses. So he set out to open a new kind of restaurant, with a new business model. In this episode, he tells us about how he accomplished that with his latest venture, Pasta Supply Co. in San Francisco.See omnystudio.com/listener for privacy information.

Selling hydrogen to make fertilizer is a huge business. It also drives tons of carbon emissions. Rob Hanson, the co-founder and CEO of a company called Monolith is trying to create hydrogen without emissions -- and to do it at scale, at a competitive price. A key tool he’s using: The biggest plasma torch ever built.See omnystudio.com/listener for privacy information.

Frances Frei and Anne Morriss are the co-founders of a training and consulting company called The Leadership Consortium. Together they specialize in helping leaders build trust within their companies. They also co-host a podcast called Fixable, which is a TED show produced by Pushkin Industries. Also, Frances is a professor at Harvard Business School. In today’s show, Frances and Anne share the story of their work with Uber. It started back in 2017, when a Harvard Business School alum who was working at Uber came to Frances and said the company needed her help.See omnystudio.com/listener for privacy information.

When a Dutch crime reporter makes an unbelievable discovery, a small-town murder case begins to look like an international assassination plot. Enjoy this episode from Hot Money: The New Narcos, a podcast from Pushkin Industries and the Financial Times. See omnystudio.com/listener for privacy information.