a16z Podcast

Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race.To make sense of it all, Erik Torenberg is joined by Dylan Patel, chief analyst at SemiAnalysis, joins Sarah Wang, general partner at a16z, and Guido Appenzeller, a16z partner and former CTO of Intel’s Data Center and AI business unit. Together, they dig into what the deal means for Nvidia, Intel, AMD, ARM, and Huawei; the state of US-China tech bans; Nvidia’s moat and Jensen Huang’s leadership; and the future of GPUs, mega data centers, and AI infrastructure. Resources: Find Dylan on X: https://x.com/dylan522pFind Sarah on X: https://x.com/sarahdingwangFind Guido on X: https://x.com/appenzLearn more about SemiAnalysis: https://semianalysis.com/dylan-patel/ Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Honestly with Bari Weiss, we share a special conversation featuring a16z general partner Katherine Boyle in the wake of Charlie Kirk’s shocking assassination.Katherine reflects on what courage means in a culture where words and debate are increasingly met with violence. Drawing on faith, history, and her own response to recent tragedies, she discusses the idea of martyrdom, not only in its most extreme sense, but also in the small, everyday choices to speak the truth despite risk. Timecodes: 0:00  Introduction 0:49  Remembering Charlie Kirk2:46  The Meaning of Martyrdom4:49  Courage and the Choice We Face9:16  Returning to Normalcy10:35  The Age of Extremes12:15 Words, Violence, and the Next Generation14:10  Reclaiming the Center18:18  The Power and Danger of Rhetoric21:55  The Call to Speak Up Resources: Listen to more from Honestly: https://podcasts.apple.com/za/podcast/honestly-with-bari-weiss/id1570872415Find Bari on X: https://x.com/bariweissFind Katherine on X: https://x.com/KTmBoyle Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The web is unhealthy, and AI agents are about to rewrite how we shop.In this episode, a16z General Partner Alex Rampell and Partner Justine Moore explore how AI agents will change commerce and the implications for Google’s business model, affiliate marketing, online shopping, and more. Timecodes: 0:00 Introduction 0:12 The Role of AI Agents in Commerce1:28 Affiliate Marketing & Impulse Buys4:02 Observing Consumer Behavior & AI6:08 Dynamic Pricing & E-commerce Trends7:20 Online vs. Offline Shopping Behaviors10:09 The Challenge of Attribution in Commerce12:19 Aggregators, Brands, and Business Models15:24 Trend Cycles & Single SKU Retailers17:49 Google, Search, and the Freemium Model22:41 The Unhealthy Web & Commercialization26:04 Video Reviews & Trust in Commerce29:10 The Costco Model & Consumer Trust33:15 AI’s Impact on Different Types of Purchases39:56 The Future: Specialized Shopping Agents40:16 Opportunities for New Durable Companies44:18 The Merchant Side: Infrastructure for AI Agents Resources: Read the article: http://a16z.com/ai-x-commerce/Find Alex on X: https://x.com/arampellFind Justine on X: https://x.com/venturetwins Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software?In this episode, General Partner Anjney Midha goes behind the scenes with one of Codex’s product leads- Alexander Embiricos - to unpack its origin story, why its PR success rate is so high, the safety challenges of autonomous agents, and what this all means for developers, students, and the future of coding. Timecodes:0:00 Intro: The Vision for AI Agents1:25 Codex’s Origin and Naming3:20 Early Prototypes and Agent Form Factors6:00 Cloud Agents: Safety and Security9:40 Prompt Injection and Attack Vectors12:00 PR Merging: Metrics and Transparency17:00 The Future of Code Review and Automation20:00 User Adoption: Internal vs. External Surprises22:00 Multi-Turn Interactions and Product Learnings29:30 Best-of-N, Slot Machine Analogy, and Creativity33:00 Human Taste, Iteration, and Collaboration40:00 AI’s Impact on Software Engineering Careers45:00 Education, CS Degrees, and AI Integration49:00 Prototyping, Hackathons, and Speed to Magic55:00 Legacy Code, Modernization, and Global Adoption1:00:00 Enterprise, Security, and Air-Gapped Environments1:05:00 Product Roadmap and Future of Codex1:10:00 Advice for Founders and Startups1:15:00 Education Reform and Project-Based Learning1:20:00 Hiring, Building, and New Grad Advice Resources: Find Alex on X: https://x.com/embiricoFind Anjney on X: https://twitter.com/AnjneyMidha Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Can we make science as fast as software? In this episode, Erik Torenberg talks with Patrick Hsu (cofounder of Arc Institute) and a16z general partner Jorge Conde about Arc’s “virtual cells” moonshot, which uses foundation models to simulate biology and guide experiments. They discuss why research is slow, what an AlphaFold-style moment for cell biology could look like, and how AI might improve drug discovery. The conversation also covers hype versus substance in AI for biology, clinical bottlenecks, capital intensity, and how breakthroughs like GLP-1s show the path from science to major business and health impact. Resources:Find Patrick on X: https://x.com/pdhsuFind Jorge on X: https://x.com/JorgeCondeBio Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this conversation from Lenny’s Podcast, Ben Horowitz joins Lenny to discuss the psychological muscle every founder needs, why hesitation can be fatal for CEOs, when it’s time to replace a founder, and how to normalize failure while building confidence. They also explore the Databricks founding story, investing in Adam Neumann after WeWork, whether AI is in a bubble, where the real opportunities lie, and Ben’s work with the Paid in Full Foundation supporting hip-hop pioneers. The result is a candid look at leadership, product management, and what it takes to build enduring companies. Timecodes: 00:00 Introduction 00:22 The Psychology of Leadership & Decision-Making02:41 Leadership lessons from Shaka Senghor07.56 Struggle, Pain, and Growth as a CEO 10:15 Running toward fear and why hesitation kills companies19:35 Who shouldn’t start a company22:36 The Databricks story: thinking bigger24:54 Managerial leverage and CEO psychology28:06 When founders should be replaced as CEOs31:20 Normalizing failure for CEOs37:57 Counterintuitive lessons about building companies42:31 “Good Product Manager/Bad Product Manager”48:21 Product managers as leaders51:16 Why a16z invested in Adam Neumann after WeWork56:23 Is AI in a bubble?01:02:43 The biggest opportunities in AI01:12:51 Why U.S. leadership in AI matters01:18:53 The Paid in Full Foundation for hip-hop pioneers01:23:18 Lightning round: book recommendations, products, and life mottos Resources: Find Ben on X: https://x.com/bhorowitzFind Ben on LinkedIn: https://www.linkedin.com/in/behorowitz/Watch more of Lenny’s Podcast: https://www.youtube.com/@LennysPodcastCheck out Lenny’s newsletter here: https://www.lennysnewsletter.com Stay Updated: Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX?si=3E8B3qT9TyiwAHJ7JnaKbgListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://twitter.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The $13T U.S. mortgage market serves 50M homeowners but still runs on decades-old software. In this episode, a16z GP Angela Strange hosts Tim Mayopoulos (ex-CEO of Fannie Mae and ex-president of Blend), Mike Yu (co-founder and CEO of Vesta), and Andrew Wang (co-founder and CEO of Valon) to unpack why standardization and regulation slow change, and how modern loan-origination and servicing platforms, cleaner data, and AI can cut costs, boost transparency, and reduce errors. They also discuss policy levers that could speed innovation and what a true one-tap mortgage could look like. Timecodes: 00:00 Introduction 00:59 The Scale and Structure of the US Mortgage Market01:33 Why Mortgage Tech is Slow to Change02:00 Challenges of Standardization and Regulation03:41 The Human Side of Home Buying07:43 Old Software and Its Impact on Homeowners11:16 Data Transparency and Capital Markets13:17 Building New Mortgage Infrastructure: LOS and Servicing16:22 Operational Challenges and Opportunities in Servicing22:04 Driving Digital Adoption at Fannie Mae25:15 Modernizing Data and Appraisals28:27 Core Replacement vs. Wrappers: Tech Strategies35:29 AI in Mortgage: Today and Tomorrow40:42 AI, Regulation, and the Future of Compliance43:54 Advice for Lenders Preparing for an AI Future47:49 Visions for the Future of Mortgages Resources: Find Angela on X: https://x.com/astrangeFind Tim on LinkedIn: https://www.linkedin.com/in/timothy-j-mayopoulos-56972a45/Find Andrew on LinkedIn: https://www.linkedin.com/in/wangandrewd/Find Mike on LinkedIn: https://www.linkedin.com/in/mikeyu1/ Stay Updated: Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX?si=3E8B3qT9TyiwAHJ7JnaKbgListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://twitter.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Why do some consumer products explode into networks that reshape the internet, while others fade away?Today on the podcast, a16z general partners Anish Acharya and Chris Dixon take on that question. Anish invests in AI-native consumer products and the next wave of consumer tech. Chris is best known for his work in Web3 and network economies, and he’s also led some of a16z’s biggest consumer bets.Together, they cover the history and power of consumer networks, the exponential forces that shape how they grow, and what it all means for founders building in the age of AI. Timecodes:00:00 Introduction 00:43 The Power of Networks in Tech02:19 Moore’s Law, Composability, and Network Effects06:39 Building Networks: Tools vs. Networks10:49 Brand, Pricing, and Consumer Software Trends14:33 Movements, Communities, and Niche Markets20:02 Decentralization, AI, and the Open Web24:45 Platform Shifts and the Idea Maze29:55 Native vs. Skeuomorphic Technologies36:14 Open Source, Policy, and the Future of AI42:03 Closing Thoughts & Outro Resources: Find Chris on X: https://x.com/cdixonFind Anish on X: https://x.com/illscience Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What happens when AI collides with salesmanship, streaming-era sports, and healthcare?In this episode, Erik Torenberg is joined by Mark Cuban, entrepreneur, Dallas Mavericks co-owner, and founder of Cost Plus Drugs.Topics include fiery group chats and how dissent sharpens thinking, the sales playbook of modern politics, and concrete fixes for U.S. healthcare like ending PBM opacity, publishing real prices, and government-backed patient financing. Mark also explains how AI is pushing media from “social” to algorithmic, why he expects millions of models, and why ESOPs are an underrated wealth engine. He shares what he’d build today and weighs in on NBA economics under the new collective bargaining agreement.Timecodes: 00:00 Introduction 00:47 Salesmanship, Politics, and Social Media04:05 AI, Algorithms, and the Future of Media06:29 Fragmentation of Social Platforms09:04 Political Messaging & Economic Populism12:05 Wealth, Equity, and Employee Ownership16:39 AI’s Impact on Education and Healthcare21:32 Fixing the US Healthcare System29:39 Entrepreneurship in the Age of AI33:38 Business Success, Sports, and Investments35:32 NBA Economics and Team Building50:44 Personal Priorities & Closing Thoughts Resources: Find Mark on X: https://x.com/mcuban Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Who’s speaking up for startups in Washington, D.C.?In this episode, Matt Perault (Head of AI Policy, a16z) and Collin McCune (Head of Government Affairs, a16z) unpack the “Little Tech Agenda” for AI- why AI rules should regulate harmful use, not model development; how to keep open source open; the roles of the federal government vs states in regulating AI; and how the U.S. can compete globally without shutting out new founders. Timecodes: 0:00 – Introduction 1:12 – Defining the Little Tech Agenda4:40 – Challenges for Startups vs. Big Tech6:37 – Principles of Smart AI Regulation9:55 – History of AI Policy & Regulatory Fears19:26 – The Role of Open Source and Global Competition23:45 – Motivations Behind Policy Approaches26:40 – Debates on Regulating Use vs. Development35:15 – Federal vs. State Roles in AI Policy39:24 – AI Policy and U.S.–China Competition40:45 – Current Policy Landscape & Action Plans42:47 – Moratoriums, Preemption, and Political Dynamics50:00 – Looking Forward: The Future of AI Policy56:16 – Conclusion & DisclaimersResources: Read the Little Tech Agenda: https://a16z.com/the-little-tech-agenda/Read ‘Regulate AI Use, Not AI Development : https://a16z.com/regulate-ai-use-not-ai-development/Read Martin’s article ‘Base AI Policy on Evidence, Not Existential Angst: https://a16z.com/base-ai-policy-on-evidence-not-existential-angst/Read ‘Setting the Agenda for Global AI Leadership’:https://a16z.com/setting-the-agenda-for-global-ai-leadership-assessing-the-roles-of-congress-and-the-states/Read ‘The Commerce Clause in the Age of AI”: https://a16z.com/the-commerce-clause-in-the-age-of-ai-guardrails-and-opportunities-for-state-legislatures/Find Matt on X: https://x.com/MattPeraultFind Collin on X: https://x.com/Collin_McCune Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stainless founder Alex Rattray joins a16z partner Jennifer Li to talk about the future of APIs, SDKs, and the rise of MCP (Model Context Protocol). Drawing on his experience at Stripe—where he helped redesign API docs and built code-generation systems—Alex explains why the SDK is the API for most developers, and why high-quality, idiomatic libraries are essential not just for humans, but now for AI agents as well.They dive into:The evolution of SDK generation and lessons from building at scale inside Stripe.Why MCP reframes APIs as interfaces for large language models.The challenges of designing tools and docs for both developers and AI agents.How context limits, dynamic tool generation, and documentation shape agent usability.The future of developer platforms in an era where “every company is an API company.”Timecodes: 0:00 – Introduction: APIs as the Dendrites of the Internet1:49 – Building API Platforms: Lessons from Stripe3:03 – SDKs: The Developer’s Interface6:16 – The MCP Model: APIs for AI Agents9:23 – Designing for LLMs and AI Users13:08 – Solving Context Window Challenges16:57 – The Importance of Strongly Typed SDKs21:07 – The Future of API and Agent Experience24:45 – Lessons from Leading API Companies26:14 – Outro and DisclaimersResources: Find Alex on X: https://x.com/rattrayalexFind Jennifer on X: https://x.com/JenniferHliStay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Taken from The Oprah Podcast, this special episode brings together Shaka Senghor, a16z cofounder Ben Horowitz, and Oprah Winfrey for a powerful conversation on resilience and transformation.Shaka, a resilience expert, motivational speaker, and bestselling author of Writing My Wrongs, shares his journey from incarceration to redemption along with insights from his new book, How to Be Free. Full of hard-earned wisdom and practical tools, it’s a guide for anyone seeking freedom in their own life.Timecodes: 0:00 Introduction 1:30 Shaka’s Journey: From Prison to Freedom4:10 The Power of Narrative and Mindset6:10 Active Journaling & Writing My Wrongs8:45 Escaping Life’s Hidden Prisons10:00 The Role of Forgiveness16:40 Healing Family Relationships21:00 Unconditional Forgiveness & True Freedom22:40 Resilience as a Spiritual Principle24:15 Mentorship & Meeting Ben Horowitz28:55 Lessons on Success and Failure30:20 The Meaning of a Pardon31:50 Life After Prison: Finding Joy in Freedom32:30 Advice for Listeners: How to Begin Your Own Journey35:15 Closing Thoughts Resources: Find Shaka on X: https://x.com/ShakaSenghoFind Ben on X: https://x.com/bhorowitzFind Oprah on Instagram: https://www.instagram.com/oprahpodcast/Listen to the full podcast:https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLIhttps://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Is non-consensus investing overrated—or the secret to venture returns?a16z General Partner Erik Torenberg is joined by Martín Casado (General Partner, a16z) and Leo Polovets (General Partner, Humba Ventures) to unpack the debate that lit up venture Twitter/X: should founders and VCs chase consensus, or run from it?They explore what “consensus” really means in practice, how market efficiency shapes venture outcomes, why most companies fail from indigestion, not starvation, and the risks founders face when they’re too far outside consensus. Timecodes: 00:00 Introduction 01:04 Defining Consensus and Market Efficiency06:30 The Role of Hot Rounds and Market Signals10:25 Founder Perspective: Risks of Non-Consensus13:19 Investor Perspective: Indigestion vs. Starvation18:28 Market Cycles & Sector Hype23:55 The Evolution of Venture Market Efficiency26:29 Case Studies & Personal Anecdotes33:02 Fund Size, Ownership, and the Impact on Strategy51:40 The Future of Venture: Multi-Stage vs. Seed Funds Resources: Find Leo on X: https://x.com/lpolovetsFind Martin on X: https://x.com/martin_casado Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They cover a16z’s evolution from generalists to specialized platforms, the rise of AI infrastructure, and why today’s fiercest battles are often for talent, not market share.Timecodes:0:00 Introduction0:27 Importance of Media for VC3:50 Evolution of a16z7:00 Specialization10:32 Value of Distribution13:16 Staying Power in Infrastructure19:49 The Conflicts Dynamic26:32 State of Play in AI30:48 The Future of Coding34:58 Significance of Open Source39:48 Marc Andreessen’s Leadership44:02 The Only Sin in VC48:37 Scaling a Lot of Board SeatsResources: Listen to more from Uncapped: https://linktr.ee/uncappedpodFind Jack on X: https://x.com/jaltmaFind Uncapped on X: https://x.com/uncapped_podFind Martin on X: https://x.com/martin_casadoStay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What if the future of media isn’t controlled by algorithms or legacy institutions—but by independent voices building directly with their audiences?In this episode, Erik Torenberg is joined by Chris Best, cofounder and CEO of Substack, along with a16z general partners Katherine Boyle and Andrew Chen.We trace the origin story of Substack and its cultural impact, including how it reinvented the business model for independent media. We also explore the evolution of blogging, the rebundling of media, and what the future holds as attention becomes the scarcest resource.Timecodes: 00:00 Introduction03:50 Origins of Substack06:29 The Evolution of Blogging & Media Models09:15 Direct Audience Connection & Platform Independence10:57 Vision for Substack & The Role of Algorithms21:06 Business Models: Ads, Subscriptions, and AI26:10 The Scarcity of Attention & Value of Good Content27:45 Unbundling, Rebundling, and the Future of Media Companies37:12 Academia, Books, and Changing Content Formats44:31 Substack’s Next Phase & Closing ThoughtsResources: Find Chris on Substack: https://cb.substack.com/Find Chris on X: https://x.com/cjgbestFind Andrew Chen on Substack: https://andrewchen.substack.com/Find Andrew on X: https://x.com/andrewchenFind Katherine on X: https://x.com/KTmBoyleFind Katherine on Substack: https://boyle.substack.com/Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Venture capital has powered companies like Facebook and TikTok—but what if that same urgency fueled America’s defense and industrial base? Katherine Boyle, General Partner at Andreessen Horowitz and cofounder of the firm’s American Dynamism practice, argues this is the biggest business opportunity of our time.In this conversation from The Shawn Ryan Show, Boyle discusses the rise of defense tech startups, why optimism drives her work, and how a new generation of engineers and founders is rethinking innovation and patriotism in America. Timecodes: 0:00 Introduction 0:41 Patriotism, Optimism, and American Innovation4:27 Startups vs. Legacy Primes in Defense10:08 Venture Capital’s Unique Incentives17:21 Katherine’s Backstory: Family & Upbringing21:07 The Decline of Community & Family Pillars23:23 Polarization, Religion, and Social Fabric26:16 America’s Birth Rate Crisis29:46 Cultural Shifts and the Family Structure42:01 Katherine’s Path: Journalism to Venture Capital1:06:06 Breaking into Silicon Valley1:18:06 Investing in Defense: The Anduril Story1:37:37 The American Dynamism Movement2:04:27 Manufacturing, Space, and the Future of Defense2:14:06 Espionage, China, and National Security2:37:38 The Attack on the American Family2:48:29 Cultural Change, Suffering, and Purpose2:55:30 Closing Thoughts Resources: Find Katherine on X: https://x.com/KTmBoyleShawn Ryan Show Links YouTube:  https://www.youtube.com/channel/UCkoujZQZatbqy4KGcgjpVxQ/joinListen on Apple: https://podcasts.apple.com/us/podcast/shawn-ryan-show/id1492492083Listen on Spotify: https://open.spotify.com/show/5eodRZd3qR9VT1ip1wI7xQ?si=7abec4d61c324b24 Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this interview from the 20VC podcast, Martin Casado (a16z General Partner) joins Harry Stebbings to unpack the state of AI, the rise of coding models, the future of open vs. closed source, and how value is shifting across the stack.Martin offers a candid view of the opportunities and dangers shaping AI and venture capital today. Resources: Find Martin on X: https://x.com/martin_casadoFind Harry on X: https://x.com/harrystebbingsMore about 20VC:Subscribe on YouTube: https://www.youtube.com/@20VCSubscribe on Spotify:https://open.spotify.com/show/3j2KMcZTtgTNBKwtZBMHvl?si=85bc9196860e4466&nd=1&dlsi=d1dbbc6a0d7c4408Subscribe on Apple Podcasts:https://podcasts.apple.com/us/podcast/the-twenty-minute-vc-20vc-venture-capital-startup/id958230465Visit their Website: https://www.20vc.comSubscribe to their Newsletter: https://www.thetwentyminutevc.com/Follow 20VC on Instagram:  https://www.instagram.com/20vchq/#Follow 20VC on TikTok: https://www.tiktok.com/@20vc_tok Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What are real consumers actually doing with AI today?In this episode, a16z consumer investors Olivia Moore and Justine Moore break down the fifth edition of our Consumer AI 100, a biannual ranking of the most used AI-native web and mobile products across the globe. Timecodes:  0:00 Introduction1:45 New Companies & Trends3:32 Companionship & Creative Tools4:20 Big Tech on the List: Google’s Impact6:24 Chinese AI Companies & Global Trends10:19 Vibecoding: A New Trend13:40 AI All-Stars: Consistent Top Performers15:30 Network Effects & Product Experience17:20 Enterprise Adoption & Prosumer Growth19:40 Biggest Takeaways21:09 Grok's debut22:56 Future predictions25:14 Closing & Audience Engagement Resources:Read more about the Top Gen 100: http://a16z.com/100-gen-ai-apps-5/Find Olivia on X: https://x.com/omooretweetsFind Justine on X: https://x.com/venturetwins Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What exactly is an AI agent, and how will agents change the way we work?In this episode, a16z general partners Erik Torenberg and Martin Casado sit down with Aaron Levie (CEO, Box) and Steven Sinofsky (a16z board partner; former Microsoft exec) to unpack one of the hottest debates in AI right now.They cover:Competing definitions of an “agent,” from background tasks to autonomous internsWhy today’s agents look less like a single AGI and more like networks of specialized sub-agentsThe technical challenges of long-running, self-improving systemsHow agent-driven workflows could reshape coding, productivity, and enterprise softwareWhat history — from the early PC era to the rise of the internet — tells us about platform shifts like this oneThe conversation moves from deep technical questions to big-picture implications for founders, enterprises, and the future of work. Timecodes: 0:00 Introduction: The Evolution of AI Agents0:36 Defining Agency and Autonomy1:54 Long-Running Agents and Feedback Loops4:49 Specialization and Task Division in AI6:20 Human-AI Collaboration and Productivity6:59 Anthropomorphizing AI and Economic Impact9:10 Predictions, Progress, and Platform Shifts11:31 Recursive Self-Improvement and Technical Challenges13:20 Hallucinations, Verification, and Expert Productivity16:20 The Role of Experts and Tool Adoption22:14 Changing Workflows: Agents Reshaping Work Patterns45:55 Division of Labor, Specialization, and New Roles48:47 Verticalization, Applied AI, and the Future of Agents54:44 Platform Competition and the Application Layer55:29 Closing Thoughts and Takeaways  Resources: Find Aaron on X: https://x.com/levieFind Martin on X: https://x.com/martin_casadoFind Steven on X: https://x.com/stevesi Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Erik Torenberg sits down with Ben Horowitz, Cofounder of a16z, for a candid conversation on venture capital, leadership, and the future of innovation. Recorded live at a16z’s Menlo Park offices in 2023, Ben shares practical wisdom and hard-earned lessons on navigating market cycles, building resilient companies, and why culture is a lasting competitive edge.Timecodes: 0:00 Introduction 0:49 Building a Lasting Venture Firm1:57 Product vs. Investor-Driven Firms5:17 Evolution of Andreessen Horowitz8:43 Fund Sizing & Market Opportunity11:38 Recruiting & Culture at a16z13:58 Supporting Founders & Firm Mission14:39 Governance & Firm Structure17:15 The Future of Venture Capital20:26 Riding Trends: AI, Web3, and Beyond27:06 Regulation, Open Source, and Innovation29:22 LPs, Macro, and Long-Term Strategy33:25 Advice for the Next Generation37:15 Tech Optimism & Societal Impact42:33 Closing Thoughts & Outro Resources: Find Ben on X:  https://x.com/bhorowitzSubscribe to Turpentine VC: link.chtbl.com/TurpentineVC Stay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.