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BEaTS Research Radio's Podcast

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Each week on BEaTS Research Radio at the University of Ottawa Heart Institute, early-career scientists and investigators deep dive into the ever-changing, rapidly evolving world of Science in one-on-one conversations with some of the planet's most brilliant Scientists, breaking down the science in terms you can understand
196 Episodes
Janïs Petit, du Canadian Biomaterials Student Ottawa Chapter, discute de biomarqueurs et de santé cardiovasculaire avec le professeur Faeiz Zannad de l’Université de Lorraine et de l’INSERM (France).
Areej Khanotia, a student in the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Patrick Fafard. Dr. Fafard is a full professor and also serves in leadership roles for the Global Strategy Lab at York University and the University of Ottawa, the Centre for Health Law, Policy and Ethics, the Institute for Science, Society and Policy, and the Ottawa Hub for Harm Reduction. In this episode, Dr. Fafard shares his insight on the illusions and implications of the ‘just following the science’ rhetoric in COVID-19 messaging. We explore whether policy makers are actually "following the science" or hiding behind experts to dodge the blame.Learn more: | BEaTS and Host Introduction 0:55 | Introducing Dr. Patrick Fafard!1:30 | Overview of study being discussed 4:45 | Negative concequences for leaders that rely on "the science"7:45 | Positive concequences for leaders that "follow the science"10:04 | Recommendations for leaders facing future healthcare crisis 11:52 | Future research plans extending from this work13:55 | Connecting with Dr. FafardPodcast by Areej Khanotia (Show Host), Hiba Alami Chentoufi (Audio Master), Hoda Osman (Writer Editor), Madeeha Shaikh (Producer)Music by the Underground Drive. All rights reserved. Listen more
Megan Verma from the University of Ottawa interviews Dr. Ian Colman for the TMM4950 Science Communication podcast assignment. Dr. Colman is a professor in the School of Epidemiology and Public Health at the University of Ottawa, and he directs the Applied Psychiatric Epidemiology Across the Life-course (APEAL) Lab. In this episode, Megan explores Dr. Colman's research on how prenatal maternal stress negatively impacts children's behaviour and mental health after birth. In the conversation, they highlight the impact of parenting on children — positively noting how effective parenting can mitigate adverse behaviours. Learn more: 0:06 | Podcast opening segment and introduction by host Megan Verma0:24 | Introduction to Dr. Ian Colman, his research, and the fetal programming hypothesis3:15 | Objectives of Dr. Colman's paper on prenatal maternal stress, children's mental health, and parenting6:32 | Impacts of prenatal maternal stress on children8:18 | Environmental factors contributing to mental health or behavioural problems in early childhood9:29 | Parenting behaviours that reduce the impact of prenatal maternal stress on children's mental health11:06 | Sex specific effects of parenting methods12:02 | Decreasing stress levels for pregnant people on a wider scalePodcast by Megan Verma (Host), Nassima Marouf (Producer), Ayesha Syed (Writer), Jenny Zhang (Audio Editor).This podcast features a song "Vibe Out" by Ellis Breen, available under a Creative Commons Attribution-NonCommercial license. Listen more:
In this episode, Dr. Luca Pellegrini is interviewed by Olivia Hillier, with narration by Andrew Cao, from the University of Ottawa. Dr. Pellegrini is a new professor in the department of Biochemistry, Microbiology, and Immunology and is an expert on mitochondria and  inter-organelle contacts. He joins us to discuss his team’s most recent paper, published in Cell Reports ( This publication describes his team’s discovery of the “wrappER”, a microscopic superhero in your body that plays a vital role in keeping you in top shape. Dr. Pellegrini takes us through the history of inter-organelle contacts research, the intriguing results detailed in his paper, and the broader implications of his findings to human health.  Learn more: 0:27 | Podcast team introduction0:42 | Meet the wrappER, the cloak that safeguards your metabolic health.2:02 | Meet Dr. Luca Pellegrini, the founder of the wrappER.3:00 | How did Dr. Pellegrini come to study the wrappER?3:46 | Why does Dr. Pellegrini like history so much?4:41 | When did researchers start to consider how contacts between organelles may be important?5:58 | Diseases related to defects in inter-organelle contacts.6:48 | What you need to know about  Anastasia et al., 2021: the paper that discovered and defined the wrappER.8:12 | The wrappeR's structure is like a burrito.8:43 | Are all mitochondria wrapped by the wrappER?9:01 | The wrappER is not limited to liver cells.9:38 | What else can the wrappER wrap?10:12 | Dynamics of the wrappER and mitochondria.11:32 | How long did it take to make these discoveries of the wrappER?11:44 | The team behind the discovery.12:40 | What the wrappER can teach us about how our bodies regulate fat.13:18 | The wrappER and treatments for fat-related diseases and disorders.13:55 | Dr. Pellegrini's plans as a new profressor and principal investigator at the University of Ottawa.14:22 | Wrapping up: thank you to Dr. PellegriniPodcast by Andrew Cao (Narrator and Post-Production), Olivia Hillier (Interviewer), Olivia Sommers (Producer), & Anna Wang (Writer-Editor).Music:“The Launch” by Chronox (  This song can be found on the Free Music Archive (“Nocturnal (BGM)” by LEMMiNO (  “Thannoid” by Blue Dot Sessions (   “Are We Loose Yet” by Blue Dot Sessions (   “Here” by Hyson (   
In the latest episode of 'Neural Networks,' your Neural Networks host Lillian Abebe, a passionate advocate for neuroscience and neurophilosophy, engages in a thought-provoking conversation with Dr. Georg Northoff. As a distinguished philosopher, neuroscientist, and psychiatrist leading the Mind, Brain, and Neuroethics Research Unit at the Royal Institute of Mental Health Research, Dr. Northoff shares profound insights into the intersection of philosophy, neuroscience, and psychiatry.Explore the intricacies of distinguishing between the brain and the mind, unravel the conceptual illusions of consciousness, and dive into the development of biomarkers for conditions like Complete Locked-In Syndrome (CLIS). Join Lillian and Dr. Northoff as they discuss the challenges of defining consciousness in scientific terms and the latest breakthroughs in understanding the connections between the brain and the mind.Learn more: 3:33 | Distuinguishing brain from mind5:32 | Areas of development in elucidating brain-mind connections.7:08 |  Techniques used to measure consciousness12:15 | The importance of making science accessiblePodcast by Abby Cherinet (producer), Lillian Abebe (host), Selam Yimer (writer), Xeius Tran-Wong (editor)Soundtrack by Blue Fox Music through Renderforest
This episode of Beats Radio, hosted by Danyaal Ansari, written by Shay Patel, produced by Hasssan Taleb, and edited by Anas Khoja, features an in-depth discussion with immunology expert Dr. Michele Ardolino from the University of Ottawa and the Ottawa Hospital Research Institute. The conversation centers around the fascinating interplay between the immune system and cancer, with a particular focus on the process of trogocytosis and its role in immune evasion by cancer cells. Dr. Ardolino elaborates on his groundbreaking research into how cancer cells transfer PD-1 to Natural Killer (NK) cells via trogocytosis, effectively inhibiting these critical components of the immune response. This detailed exploration sheds light on the sophisticated mechanisms cancer cells employ to evade immune detection and opens up discussions about potential therapeutic strategies targeting these interactions. - Introduction0:57 - Trogocytosis Explained2:51 - Choosing Trogocytosis for PD-1 Transfer Study5:00 - NK Cells' Functional Variability8:10 - Immune System's Complexity & Beauty10:50 - Rapid Fire Q&A14:27 - Closing RemarksPodcast by Danyaal Ansari (Host), Shay Patel (Writer), Hasssan Taleb (Producer), Anas Khoja (Editor)Music by "Podcast Background Music" 
Alzheimer's is a disease unique in the lack of treatment dand diagnostic techniques aimed at mitigating it's effects.  To address these issues, researchers at Dr. Clifford Cassidy’s neuroscience lab are investigating the use of novel imaging techniques that have great potential to improve both our understanding of molecular mechanisms underlying Alzheimer’s and improve our ability to predict the development of it’s symptoms. At the heart of these new techniques is a brain structure called the locus coeruleus (LC), which is the primary site of release of a chemical called norepinephrine. It has already been established that gradual degeneration of the LC is an important feature of alzheimer’s disease. However, the contribution of this degeneration to development of disease symptoms remains poorly understood due to limitations in existing imaging techniques. To solve this issue, Dr. Casidy’s lab is investigating the use of Neuromelanin, a pigment found abundantly in the LC to more accurately detect this structure’s degeneration and its relation to Alzheimer’s and its symptoms.Learn more: I Podcast Introduction02:32 I Overview of the Cassidy Lab4:24 I What is NM-MRI?6:40 I Overview of the Paper about NM-MRI9:40 I What is the role of neuroadronergic system in psychotic symptom progression?12:20 I What is the broader role of NM-MRI14:30 I OutroPodcast by Patrick Chary(Host), Abdul Karim Halal (Producer), Elijah Van Dinther (Script), Nicholas Lafreniere (Editor).Soundtrack by the Underground Drive, Song title: Nobody. All rights reserved.Listen more:
Amy Stewart from the University of Ottawa speaks with Dr. Marta Cerruti, a professor in the Department of Mining and Materials Engineering at McGill University, a prominent figure in the research field of bio-synthetic materials, and the team leader of the Bio-Interface lab. As of today, Dr. Cerruti is the co-director of the McGill Institute for Advanced Materials and an associate member of the Faculty of Dentistry and the Department of Bioengineering. In the Bio Interface lab, her work centers around the incorporation of implants, tissues and drugs into the human body, as well as how minerals such as calcium and magnesium are formed in living organisms that help her address the questions of curing mineral-based diseases. Today, we'll be discussing her work centering around mineral deposits that lead to aortic valve stenosis.Learn more: l Introduction to BEaTS and Dr. Cerruti1:25 l What is aortic valve calcification and what are the causes?2:54 l Are there other minerals that develop in the heart?3:45 l What are the methods used to view clacium deposits?7:06 l Differences in calcification between men and women12:01 l Future research14:10 l Conclusion14:45 l CreditsPodcast by Amy Stewart (Show Host), Shikshita Singh (Producer), Minh Tran (Writer Editor), Jade Gamelin Kao (Audio Master).Soundtrack by Lexin_music featuring the song "sicence documentary". All rights reserved. Listen more:
Fiona Haugen of the University of Ottawa speaks with Dr. Smita Pakhale of the Ottawa Hospital Research Institute about the impact of health inequities on the development of obstructive lung diseases in urban poor populations. Dr. Pakhale is a Senior Scientist, staff respirologist at The Ottawa Hospital, and associate professor at the University of Ottawa who created The Bridge Engagement Center. The Bridge conducts research in partnership with and to improve the well-being of underserved populations in Ottawa, Ontario. Learn more: | Introduction01:10 | Overview of Dr. Pakhale's research02:51 | The Bridge Engagement Center03:44 | Tobacco and Ottawa's urban poor population05:51 | Social determinants of health and lung disease07:18 | Building trust with marginalized communities09:15 | Unjustified exclusion of underserved communities in mainstream research 11:22 | Addressing inequities in health and research13:01 | How can we do our part?14:12 | Conclusion and thanksPodcast by Fiona Haugen (host and graphic design), Amandine Courtemanche (writer), Mairead Green (producer), Jade Poirier (audio-producer and writer)Soundtrack by Grand_Project from Pixabay. All rights reserved. Listen more: 
Nandini Biyani from the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Leila Mostaço-Guidolin, an assistant professor at Carleton University in the Department of Systems and Computer Engineering. With a focus in 3D-bioprinting, Dr. Mostaço-Guidolin leads a tissue engineering and bioimaging lab. In today's podcast, Dr. Mostaço-Guidolin dives into her research regarding the use of a microfluidic-based 3D bioprinting technology to synthesize new vasculature.            Learn more: | Topic Introduction 0:36 | Guest introduction 1:25 | Interest in the field of 3D bioprinting?3:23 | Elaborating on the study 4:51 | Specific choice of SV-ARBEC cells 8:31 | What is microfluidic-based 3D bioprinting? 9:56 | Limitations of the study 12:56 | Future steps 14:00 | Catch you later!   This podcast was produced by Nandini Biyani (the show host), Esha Gahunia (the writer editor) & Gurrose Gahla (the audio master).                                        Soundtrack by The Underground Drive. All rights reserved. Listen more:
Siyona Kassel, a Translational and Molecular Medicine student at the University of Ottawa, interviews Dr. Juan Valerio Cauich-Rodriguez. Dr. Cauich-Rodriguez is a researcher at the Centro de Investigación Científica de Yucatán in Mexico, possessing a Bachelor of Science in Industrial Chemistry, a Masters in Polymer Science & Technology, and a PhD in Biomedical Materials. He is currently engaged in the development and assessment of new materials for their role in Regenerative Medicine, with a specific focus on the use of synthesized polymers. In this episode, Dr. Cauich-Rodriguez discusses his research using a unique and innovative polymer blend to advance the field of vascular grafts for medical application.Learn more: I Introduction: Cardiovascular grafts0:49 I  Intro to Dr. Juan Valerio Cauich-Rodriguez1:29  I Dr. Cauich-Rodriguez's science background and current research3:08  I  Polymers for biomedical applications in Mexico4:21  I  What are polyurethanes?6:39  I  Biomaterials as a treatment for cardiovascular disease 8:40  I  Designing synthetic vascular grafts with polymer blends10:40  I  Staying on top of the latest advancements in the field of regenerative materials12:05  I  Personalized medicine and biomaterials 13:29  I  Dr. Cauich-Rodriguez's future directionsPodcast by Siyona Kassel (Voice), Caleb Lakhani (Content Generation), Paul Nguyen (Producer and Post-Production) Credits for music: Soundtrack provided by the Underground Drive all rights reserved. Listen more:
Zachary Mitchell from the University of Ottawa speaks with Angelico Obille, a PhD candidate at the University of Toronto Institute of Biomedical Engineering in the Biological & Bioinspired Materials Laboratory. Tune in to learn more about their research on proteins involved in freshwater mussel adhesion and how this can be applied to develop new medical adhesive technology.Learn more: I Intro01:05  I Why is it important to study freshwater mussel adhesion?02:15  I What is a byssal proteome and what does it show us?04:16  I What's special about the proteins of zebra mussels that allows them to stick so well to wet surfaces?07:38  I Can you explain why you don't fully agree with considering these mussels as an invasive species?11:52  I How have these mussels impacted our ecosystem?13:24  I What do you think about biocontrol and do you think there is a way to live harmoniously with these animals?14:15  I OutroPodcast by Liliana Austin, Safa Ghaziasgar, Samarth Chauhan, and Zachary MitchellSoundtracks by the Underground Drive. All rights reserved. Listen more:   
Devin Brain from the University of Ottawa interviews Dr. May Griffith. Dr. May Griffith is a lead researcher at Université de Montreal and holds a Canada Research Chair in Biomaterials and Stem Cell Ophthalmology. She is one of the brilliant minds behind the development of LiQD Cornea, an injectable liquid that gels in the eye to help heal corneal perforations. In this episode, Dr. Griffith shares the story that inspired her to study eye conditions and shares her incredible research focused on developing a gel for corneal regeneration.Learn more: | BEaTS and host introduction0:37 | Statistical introduction to the cornea1:01 | Introduction to Dr. May Griffith1:40 | Dr. Griffith's story of inspiration3:30 | What is a corneal perforation and how are they aquired?4:25 | Addressing problems with current treatments for corneal perforations using LiQD Cornea6:07 | LiQD Cornea administration route in relation to accessibility8:00 | Future plans for LiQD Cornea treatment 9:15 | What should patients expect from this treatment, short and long-term?10:46 | Closing remarks and creditsErica Anderson (script writing), Devin Brain (host), Rosalie Salati (audio editor), Tamara Synek (script writing).  All shared role of producerSoundtrack by The Underground Drive. All rights reserved. Listen more:
Meron Samuel Demissie from the University of Ottawa speaks with Dr. Jean-François Couture, Full Professor and Chair in the Department of Biochemistry, Microbiology and Immunology in the Faculty of Medicine at the University of Ottawa. Tune in to learn more about their studies on structural biology and epigenetics to understand the importance of small molecules and proteins' functions for the treatments of different conditions such as cancer.Learn more:  |  Introduction and Description1:27  |  X-Ray Crystallography2:55  | Epigenetic Processes5:15  | Role of X-Ray Crystallography in protein-protein interaction, precisely histones10:13 | Closing Remarks and Advice for traineesCredits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more 
Félix Labonté, an undergraduate student in the Translational and Molecular Medecine program at the University of Ottawa speaks with Dr. Dylan Burger. Dr. Burger is an associate professor at The University of Ottawa in The Department of Cellular and Molecular Medicine, cross-appointed member in the School of Pharmaceutical Sciences, and an investigator at The Ottawa Hospital Research Institute. Tune into today's podcast to learn more about Dr. Burger's research, published in the Journal of Extracellular Vesicles which demonstrates how extracellular vesicles secreted by the kidneys could potentially be used for targeted therapy advancing our knowledge on diabetic nephropathy and treatments. Learn more: 0:16  | Introduction1:00  | Dr. Dylan Burger Introduction1:44  | What are extracellular vesicles and what role do they play in healthy cells?2:52  | What is diabetic nephropathy and why is your lab interested in this condition?3:55  | What is the impact of diabetic kidney disease on microparticles released by the podocytes?4:35  | What is the impact of the microparticles released by the podoocytes?5:57  | What would be the next steps for your lab to complete to understand the mechanism of intracellular communication between the podocytes and the proximal tubule epithelial cells?7:16  | Are there any specific medications being tested right now as potential treatments for these types of kidney diseases?8:26  | For extracellular vesicles in general, what's their potential to be used as biomarkers for certain diseases? How could it be used in a clinical setting?10:24  | Closing remarks10:48  | ConclusionSoundtracks by the Underground Drive. All rights reserved. Listen more:
Hannah Deyell from the University of Ottawa interviews Dr. Adam Rudner on his current research and experience. Dr. Adam Rudner is an Associate Professor at the University of Ottawa in the Department of  Biochemistry, Microbiology and Immunology, a member of the SEA-PHAGES and SEA-GENES programs, and the coordiantor of uOttawa Phage Hunters. The primary research focuses of Dr. Rudner's team are exploring the potential applications for baceteriophage therapy, building essential research skills, and exploring bacteriophages with interesting genomic sequences. In this episode, Dr. Rudner explores how bacteriophages can target antibiotic resistance for patients with disseminated bacterial infections, how his lab is working to increase the pool of available phages, and how personalized medicine can be used to improve patient outcomes with phage therapy. Learn more:  | Introduction01:00  |  Dr. Adam Rudner's recent research focuses and ongoing projects 02:13  |  The roles of bacteriophages and how they function to treat bacterial infections03:04  |  Advantages of bacteriophage therapy over tradtional antibiotics in the context of antibiotic resistance 04:13  |  Challenges associated with research related to bacteriophages / limitations of bacteriophage therapy 05:44  |  Primary motivators for using engineered bacteriophages as a treatment for 15-year old cystic fibrosis patient07:51  |  The purpose of engineering bacteriophages to effectively treat the patient10:23  |  The undergraduate SEA-PHAGES Program 11:48  |  Dr. Adam Rudner's research advice to undergraduate students 13:17  |  ConclusionCredits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more
Rama El Hakim from the University of Ottawa speaks with Dr. Doug Coyle, Professor at the University of Ottawa in the School of Epidemiology and Public Health. Listen in to learn about Dr. Coyle's recent work in CJC Open, which determines that lifesaving drug Canakinumab needs a cost reduction of 91% to be feasible in Canada. Learn more:  |  Introduction01:41  |  Dr. Coyle's Current Research Focuses 03:37  |  Applications to Other Healthcare Systems 08:14  |  Is the suggested 91% price reduction of Canakinumab feasible? 10:05  |  Translating this research to clinical settings 11:05  |  Advice to the general public 14:52   | Wrap-Up Soundtrack by Secret Ops. All rights reserved. Learn more:
In this special episode, Dr. Gabriela Ghisi talks about the educational component and its impact on cardiac rehabilitation, the challenges of cardiac rehabilitation programs across the globe, and the advancements of the International Council of Cardiovascular Prevention and Rehabilitation. Learn more:
Spinal Muscular Atrophy (SMA) is a devastating genetic disease that causes muscle weakness and atrophy (shrinking of muscles) in children. There is currently no cure for this disease; however, base editing, a type of gene therapy, provides potential. Dr. Rasthmi Kothary is the Deputy Scientific Director and Senior Scientist at the Ottawa Hospital Research Institute. His lab focuses on understanding the mechanisms that underlie muscle and nervous system integrity. In this episode, Dr. Kothary gives us a greater insight on what SMA is, how it is currently being treated, and his research so far on a new base editing system to potentially cure this disease. Episode produced & hosted by: Nicole Chu Learn more:
 Jinane E. from the University of Ottawa interviews Dr. Mete Civelek, a distinguished researcher and professor in the department of biomedical engineering at the University of Virginia. Dr. Civelek’s research focuses on studying the complex interactions between genes and the environment that increase the risk of heart disease and type 2 diabetes. Dr. Civelek and his team employ cutting-edge bioinformatics tools to unravel the molecular pathways associated with these diseases and to develop personalized medicine strategies for cardiovascular and metabolic disorders. If you’ve ever been curious about computational biology applied to gene expressions, this episode is a unique opportunity to gain insights. Dr. Civelek provides an in-depth exploration of his research in systems genetics aimed at understanding cardiometabolic diseases.Learn more:
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