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Osterholm Update
Author: CIDRAP
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A weekly report on the COVID-19 pandemic from infectious disease expert Michael Osterholm, PhD, MPH. Dr. Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota and has spent a career investigating outbreaks. Since 2005, he has emphasized supply chain and other vulnerabilities and a critical need for pandemic preparedness. In this podcast, Dr. Osterholm dissects the latest COVID-19 news, data, and guidance.
CIDRAP’s Chris Dall, MA, is the cohost of the Osterholm Update and a reporter for CIDRAP News. http://www.cidrap.umn.edu
173 Episodes
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<p>In "A Coronavirus Dance," Dr. Osterholm and Chris Dall discuss the latest COVId trends, the upcoming winter respiratory virus season, and a UN meeting on antimicrobial resistance. Dr. Osterholm also provides an update on long COVID research and shares another "This Week in Public Health History" segment. </p>
<p><a href="https://www.covidtests.gov/">COVIDTests.gov</a></p>
<p><a href="https://www.cidrap.umn.edu/covid-19/covid-19-reinfection-ups-risk-long-covid-new-data-show">COVID-19 reinfection ups risk of long COVID, new data show</a> (Jim Wappes, <em>CIDRAP News</em>)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/study-sheds-new-light-severe-covids-long-term-brain-impacts">Study sheds new light on severe COVID's long-term brain impacts</a> (Lisa Schnirring, <em>CIDRAP News</em>)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/common-diabetes-drug-linked-lower-rate-long-covid">Common diabetes drug linked to lower rate of long COVID</a> (Stephanie Soucheray, <em>CIDRAP News</em>)</p>
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<p>In this episode, Dr. Osterholm and Chris Dall cover the latest infectious disease news on topics including H5N1, mpox, measles, and polio. Dr. Osterholm also answers an ID query on updated COVID-19 vaccines and gives his thoughts on a controversial study on Paxlovid.</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/evidence-growing-covid-antivirals-cut-poor-outcomes-long-covid-experts-say">Evidence growing for COVID antivirals to cut poor outcomes, long COVID, experts say</a> (<em>CIDRAP News</em>)</p>
<p><a href="https://www.foreignaffairs.com/united-states/world-not-ready-next-pandemic">The world is not ready for the next pandemic</a> (Michael Osterholm & Mark Olshaker, <em>Foreign Affairs</em>)</p>
<p><a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html">Interim clinical considerations for use of COVID-19 vaccines in the United States</a> (CDC)</p>
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<p>In this episode, Dr. Osterholm and Chris Dall discuss H5N1 in cattle, mpox in the Democratic Republic of Congo, and the risk of different vectorborne diseases in the United States. Dr. Osterholm also discusses the newly available 2024-2025 COVID vaccines and shares the latest "This Week In Public Health History" segment. </p>
<p><a href="https://www.foreignaffairs.com/united-states/world-not-ready-next-pandemic">The world is not ready for the next pandemic</a> (Michael Osterholm & Mark Olshaker, <em>Foreign Affairs</em>)</p>
<p><a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html">Interim clinical considerations for use of COVID-19 vaccines in the United States</a> (CDC)</p>
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<p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19"><strong>MORE EPISODES</strong></a> </p>
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<p>In this addendum to Episode 164, Dr. Osterholm and Chris Dall discuss the approval of the 2024-2025 mRNA COVID-19 vaccines. </p>
<p><a href="https://www.cidrap.umn.edu/covid-19/fda-green-lights-seasons-updated-mrna-covid-vaccines">FDA green-lights season's updated mRNA COVID vaccines</a> (Mary Van Beusekom, CIDRAP News)</p>
<p>Listen to <em>Episode 164: Only the Beginning</em> <a href="https://www.cidrap.umn.edu/covid-19/episode-164-only-beginning">here</a></p>
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<p dir="ltr">In "Only the Beginning," Dr. Osterholm and Chris Dall discuss the mpox public health emergency and the latest COVID-19 and H5N1 trends. Dr. Osterholm also answers an ID Query on COVID-19 vaccine access and commemorates the legacy of Ryan White.</p>
<p dir="ltr"><a href="https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html">Use of COVID-19 Vaccines in the United States: Interim Clinical Considerations</a> (CDC)</p>
<p dir="ltr"><a href="https://www.cidrap.umn.edu/mpox">CIDRAP Mpox News</a></p>
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<p>In this episode, Dr. Osterholm and Chris Dall discuss the current COVID-19 and H5N1 trends, answer a COVID query about influenza vaccination, and share the latest news on a listeria outbreak linked to deli meat. </p>
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<p>In "Class is Not Dismissed," Dr. Osterholm and Chris Dall review the latest trends in COVID-19 and discuss new human cases of H5N1 influenza. Dr. Osterholm also answers an ID Query on Paxlovid eligibility and shares his perspective on timing the next dose of COVID-19 vaccine.</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/risk-long-covid-has-ebbed-during-pandemic-mostly-thanks-vaccines-new-data-reveal">Risk of long COVID has ebbed during pandemic, mostly thanks to vaccines, new data reveal</a> (CIDRAP News)</p>
<p><a href="https://www.pbs.org/newshour/health/how-a-hotel-convention-became-ground-zero-for-this-deadly-bacteria">How a hotel convention became ground zero for this deadly bacteria</a> (PBS News)</p>
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<p>In "What's Going On and Why Does it Matter?," Dr. Osterholm and Chris Dall discuss the SARS-CoV-2 wastewater surveillance data, the H5N1 influenza outbreak in dairy cattle, and a CDC Health Alert on dengue virus. </p>
<p><a href="https://emergency.cdc.gov/han/2024/han00511.asp">Increased Risk of Dengue Virus Infections in the United States</a> (Health Alert Network, <em>CDC</em>)</p>
<p><a href="https://history.nih.gov/pages/viewpage.action?pageId=8883184">Dr. Joseph Goldberger & the War on Pellagra</a> (Office of NIH History & Stetten Museum, <em>National Institutes of Health</em>)</p>
<p><a href="https://www.sciencehistory.org/stories/magazine/joseph-goldbergers-filth-parties/">Joseph Goldberger’s Filth Parties</a> (Sam Kean, <em>Science History Institute</em>)</p>
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<p>In this episode, Dr. Osterholm and Chris Dall discuss the U.S. response to H5N1 cases in dairy cattle, the latest long COVID research, and a recent New York Times article on the origins of the COVID-19 pandemic.</p>
<p><a href="https://nap.nationalacademies.org/catalog/27756/long-term-health-effects-of-covid-19-disability-and-function">Long-term health effects of COVID-19: disability and function following SARS-CoV-2 infection</a> (National Academies of Sciences, Engineering, and Medicine)</p>
<p><a href="https://journals.asm.org/doi/10.1128/jvi.00365-23">A critical analysis of the evidence for the SARS-CoV-2 origin hypotheses</a> (Alwine et al., <em>Journal of Virology</em>)</p>
<p><a href="https://www.nbcnews.com/news/amp/rcna26836">'I am a homosexual. I am a psychiatrist': how Dr. Anonymous changed history</a> (Jillian Eugenios, <em>NBC News</em>)</p>
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<p>In "Uncharted Territory," Dr. Osterholm and Chris Dall cover the latest H5N1 news and updates to the COVID-19 vaccine formulation. Dr. Osterholm also discusses how this summer's weather may impact mosquito and tick populations, and answers an ID query on culling dairy cows. </p>
<p><a href="https://www.cdc.gov/bird-flu/spotlights/ferret-study-results.html?CDC_AAref_Val=https://www.cdc.gov/flu/avianflu/spotlights/2023-2024/ferret-study-results.htm">CDC Reports A(H5N1) Ferret Study Results</a> (CDC)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/fda-panel-supports-switch-jn1-fall-covid-vaccines">FDA panel supports switch to JN.1 for fall COVID vaccines</a> (CIDRAP News)</p>
<p><a href="https://nap.nationalacademies.org/catalog/27756/long-term-health-effects-of-covid-19-disability-and-function">Long-Term Health Effects of COVID-19: Disability and Function Following SARS-CoV-2 Infection</a> (National Academies)</p>
<p><a href="https://www.noaa.gov/news-release/noaa-predicts-above-normal-2024-atlantic-hurricane-season">NOAA predicts above-normal 2024 Atlantic hurricane season</a> (NOAA)</p>
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<p>In "An Unfolding Saga," Dr. Osterholm and Chris Dall discuss the latest H5N1, COVID-19, and measles news. Dr. Osterholm also answers an ID query on influenza and shares the latest "This Week in Public Health History" segment. </p>
<p><a href="https://www.cidrap.umn.edu/avian-influenza-bird-flu/study-confirms-infection-mice-fed-h5n1-contaminated-raw-milk">Study confirms infection in mice fed H5N1-contaminated raw milk</a> (CIDRAP News)</p>
<p><a href="https://erictopol.substack.com/p/akiko-iwasaki-the-immunology-of-covid">Akiko Iwasaki & Eric Topol Interview: The Immunology of Covid and the Future</a> (Ground Truths)</p>
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<p>In "Lungs & Udders," Dr. Osterholm provides updates on H5N1 influenza, COVID-19, and mpox. He also shares his thoughts on a recent WHO report about airborne transmission and a study on the use of a diabetes drug to treat COVID-19.</p>
<p><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00244-7/fulltext">Airborne pathogens: controlling words won’t control transmission</a> (Greenhalgh et al., <em>The Lancet</em>)</p>
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<p>In "H5N1: An Impending Crisis," Dr. Osterholm and Chris Dall discuss the spread of H5N1 avian influenza in US<br>dairy cows, cover the latest COVID-19 trends, review two articles on long COVID, and answers a listener question about the safety of raw milk and other dairy products. Dr. Osterholm also shares a timely "This Week in Public Health History" segment and interviews the final two members of the podcast team.</p>
<p> </p>
<p><a href="https://www.statnews.com/2024/04/25/h5n1-bird-flu-cows-outbreak-likely-widespread/">Early tests of H5N1 prevalence in milk suggest U.S. bird flu outbreak in cows is widespread</a> (<em>STAT, subscription may be required</em>)</p>
<p><a href="https://www.statnews.com/2024/04/24/h5n1-bird-flu-vaccine-preparedness/">Massive amounts of H5N1 vaccine would be needed if there’s a bird flu pandemic. Can we make enough?</a> (<em>STAT, subscription may be required</em>)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/long-covid-patients-more-likely-report-psychiatric-symptoms-cost-barriers-therapy">Long-COVID patients more likely to report psychiatric symptoms, cost barriers to therapy</a> (<em>CIDRAP News</em>)</p>
<p><a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00171-3/fulltext">The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China</a> (<em>Lancet Infectious Diseases</em>)</p>
<p> </p>
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<ul> </ul>
<p>In "Brighter Days Ahead," Dr. Osterholm and Chris Dall discuss the latest national and international COVID trends, recent research on long COVID, and measles cases in the U.S. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews two members of the podcast team.</p>
<p>Please fill out our <a href="https://redcap.ahc.umn.edu/redcap/surveys/?s=DKAXDYKTDXCN4HLT">Listener Feedback Survey</a>!</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/three-studies-spotlight-long-term-burden-covid-us-adults">Three studies spotlight long-term burden of COVID in US adults</a> (Van Beusekom, <em>CIDRAP News</em>)</p>
<p><a href="https://www.science.org/content/article/long-covid-trials-aim-clear-lingering-virus-help-patients-need">Lessons in persistence: new long COVID trials aim to clear lingering virus—and help patients in dire need</a> (Couzin-Frankel, <em>Science</em>)</p>
<p><a href="https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates">The pandemic’s true death toll</a> (<em>The Economist</em>)</p>
<p><a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs & You podcast</a></p>
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<ul> </ul>
<p>In "H5N1 Uncertainty," Dr. Osterholm and Chris Dall discuss the latest national COVID trends, a recent study on Paxlovid, and H5N1 avian flu virus infection in cattle. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews two members of the podcast team.</p>
<p>Please fill out our <a href="https://redcap.ahc.umn.edu/redcap/surveys/?s=DKAXDYKTDXCN4HLT">Listener Feedback Survey</a>!</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/swedish-study-suggests-link-between-long-covid-and-severity-illness">Swedish study suggests link between long COVID and severity of illness</a> (Stephanie Soucheray, <em>CIDRAP News</em>)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/study-long-covid-affects-8-those-covid-19-more-common-women">Study: long COVID affects 8% of those with COVID-19, is more common in women</a> (Stephanie Soucheray, <em>CIDRAP News</em>)</p>
<p><a href="https://www.cidrap.umn.edu/covid-19/new-neurologic-issues-less-likely-after-severe-covid-flu-research-suggests">New neurologic issues less likely after severe COVID than flu, research suggests</a> (Mary Van Beusekom, <em>CIDRAP News</em>)</p>
<p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2309003">Nirmatrelvir for vaccinated or unvaccinated adult outpatients with COVID-19</a> (Hammond et al., <em>New England Journal of Medicine</em>)</p>
<p><a href="https://www.nejm.org/doi/full/10.1056/NEJMe2402224">Treating acute COVID-19 — final chapters still unwritten</a> (Gandhi & Hirsch, <em>New England Journal of Medicine</em>)</p>
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<p>In "Good News in a COVID-Indifferent World," Dr. Osterholm and Chris Dall discuss the national and international COVID trends, the latest research on long COVID, and antibiotic-resistant <em>Shigella</em>. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews members of the podcast team. </p>
<ul>
<a href="https://doi.org/10.1038/s41590-024-01754-8">Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19</a> (Hanson et al., <em>Nature Immunology</em>)<br>
<a href="https://www.pewresearch.org/science/2024/03/07/how-americans-view-the-coronavirus-covid-19-vaccines-amid-declining-levels-of-concern/">How Americans view the coronavirus, COVID-19 vaccines amid declining levels of concern</a> (Tyson & Pasquini, <em>Pew Research Center</em>)<br>
<a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/spike-extensively-drug-resistant-shigella-cases-reported-uk-europe">Spike in extensively drug-resistant Shigella cases reported in UK, Europe</a> (Dall, <em>CIDRAP News</em>)<br>
<a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/cdc-warns-increase-extensively-drug-resistant-shigellosis">CDC warns of increase in extensively drug-resistant shigellosis</a> (Dall, <em>CIDRAP News</em>)<br>
<a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs & You podcast</a> — new episode coming 3/26!<br>
<a href="https://www.theguardian.com/society/2020/may/26/last-iron-lung-paul-alexander-polio-coronavirus">The man in the iron lung</a> (McRobbie, <em>The Guardian</em>)<br>
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</ul>
<p>In "A Tough Conversation," Dr. Osterholm and Chris Dall discuss the new CDC COVID isolation guidelines, a measles outbreak in Florida, and the latest news on avian influenza. Dr. Osterholm also provides an update on influenza and RSV cases in the U.S. and shares the latest "This Week in Public Health History" segment.</p>
<p><a href="https://www.cdc.gov/respiratory-viruses/guidance/background.html?CDC_AAref_Val=https://www.cdc.gov/respiratory-viruses/background/index.html">Background for CDC’s Updated Respiratory Virus Guidance</a> (CDC)</p>
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<p>In this episode, Dr. Osterholm and Chris Dall discuss COVID isolation guidelines, the BA.2.87.1 variant, and the importance of measles and other rare public health threats. </p>
<p>In "A Family Discussion," Dr. Osterholm and Chris Dall discuss the latest SARS-CoV-2 variant, consider the current and future challenges accessing Paxlovid, and explore new long COVID research. Dr. Osterholm also revisits last episode's discussion on changing public health guidelines and celebrates some canine heroes in the "This Week in Public Health History" segment. </p>
<ul>
<a href="https://www.pnas.org/doi/10.1073/pnas.2300644120">Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes</a> (Yue Zhang, <em>PNAS</em>)<br>
<a href="https://www.startribune.com/minnesota-hospitals-say-65000-days-of-care-were-avoidable-if-patients-had-somewhere-to-go/600340025/">Minnesota hospitals say 65,000 days of care were avoidable if patients had somewhere to go</a> (Jeremy Olson, <em>Star Tribune</em>)<br>
<a href="https://www.health.state.mn.us/diseases/coronavirus/paxrx.pdf">Have a Paxlovid Prescription? Low Cost Options Available</a> (Minnesota Department of Health)<br>
<a href="https://treatments.hhs.gov/">Find COVID-19 Medications</a> (Administration for Strategic Preparedness and Response, HHS)<br>
<a href="https://www.washingtonpost.com/lifestyle/2024/01/31/shelter-dog-rescue-homeless-fayetteville/">Homeless man leaves puppies at N.C. shelter with heart-tugging note</a> (Cathy Free, <em>Washington Post</em>)
</ul>
<p>In "A Period of Transition," Dr. Osterholm and Chris Dall discuss the latest COVID-19 trends in the U.S. and around the world, a recent study on long COVID, and the rise of measles cases in the United States. Dr. Osterholm also provides an update on influenza and RSV cases in the U.S. and shares the latest "This Week in Public Health History" segment. </p>
<ul>
<a href="https://www.science.org/doi/10.1126/science.adg7942">Persistent complement dysregulation with signs of thromboinflammation in active long COVID</a> (Cervia-Hasler et al., <em>Science</em>)<br>
<a href="https://erictopol.substack.com/p/lighting-up-long-covid">Lighting up long COVID</a> (Eric Topol, <em>Ground Truths</em>)<br>
<a href="http://tinyurl.com/LCEditorial">Follow up, funding critical on long COVID</a> (Jill Burcum, <em>Star Tribune</em>)<br>
<a href="https://www.cidrap.umn.edu/covid-19/does-paxlovid-prevent-long-covid-maybe-experts-suggest">Does Paxlovid prevent long COVID? Maybe, experts suggest</a> (Stephanie Soucheray, <em>CIDRAP News</em>)
</ul>
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United States
Dr. Osterholm. As the chair of the board of health in my county, I have listen to your podcast every week as a way to get real information that I need in order to make decisions for not only our community but also my organization. Time in again, your podcast has provided guidance that I needed in a sea of misinformation. During the recent episode, you were talking about N95 masks for children and how cloth face coverings are just a decoration. That seems so odd to me, and I can tell you that out of all the adults and kids who have worn a face covering in the last two years, very few have warn an N95. And yet in 2020 the rate of flu was so small, and I know that was combined with all the shutting down of the community, but what I hear you saying is that these cloth face coverings are not worth anything. And if that’s all people will wear, then what’s the point? It seems like schools have been able to stay open despite the fact the kids are just wearing a cloth face covering. Are you lit
soon the update will be "mandated COVID booster program to save humanity.... this time!" what's next to mandate? how long will the dirty unvaccinated be tolerated? can we start rounding them up soon? tune in next week to find out!
aSw
Please comment on the EU travel restriction for US residents. Do travel restrictions work?
In the states and in Canada why did the case count go down so much over the last few months? Thanks.
The UK has been in lockdown from Nov 5th, that's 5 months not 2,relaxing lockdown from april
Thank you for these very informative, honest and factual podcasts. Whilst I am listening from the UK, what you have been saying is relevant to all of us and it's been helpful to cut through the noise of the media. Thank you again.