EADV Podcast

In this episode of the EADV Podcast, Dr. Sarah Walsh is joined by Dr. Saskia Oro (Henri Mondor Hospital, Paris) and Dr. Emmanuel Contassot (University of Basel) to mark the launch of the new EADV CARD-EM Task Force. The conversation opens with the newly published European expert consensus on the diagnosis and management of acute generalised exanthematous pustulosis (AGEP), including how to identify severe cases and when oral corticosteroids are warranted over topical treatment. They go on to discuss the allergological work-up for AGEP, including patch testing and lymphocyte transformation tests, and the underlying immunology: Dr. Contassot's research showing that IL-36 and an innate immune pathway, rather than T cells alone, help drive the pustules seen in AGEP. The conversation then turns to epidermal necrolysis (SJS/TEN), covering recent research into the roles of macrophages, dendritic cells and IL-33 in disease progression, and what these findings could mean for the field's first targeted therapies. The episode closes by looking at the long-term impact of SJS/TEN on survivors, drawing on a 2023 Delphi consensus on managing post-acute sequelae and a patient cohort study, both of which point to the same conclusion: the physical and psychological consequences of these diseases can last for decades, and patients need ongoing, multidisciplinary support long after the acute phase has passed.   References: AGEP European Expert Consensus (2024) Tetart F, Walsh S, Milpied B, et al. Acute generalized exanthematous pustulosis: European expert consensus for diagnosis and management. J Eur Acad Dermatol Venereol. 2024;38(11):2073-2081. doi:10.1111/jdv.20232. 🔗 https://onlinelibrary.wiley.com/doi/10.1111/jdv.20232 Macrophages and Plasmacytoid Dendritic Cells in Epidermal Necrolysis (2025) Saizonou T, et al. Macrophages and plasmacytoid dendritic cells are recruited to the epidermis during epidermal necrolysis. J Eur Acad Dermatol Venereol. 2025. doi:10.1111/jdv.20795. 🔗 https://onlinelibrary.wiley.com/doi/10.1111/jdv.20795 Delphi Consensus on Post-Acute Sequelae of Epidermal Necrolysis (2023) Ingen-Housz-Oro S, Schmidt V, Ameri MM, et al. Post-acute phase and sequelae management of epidermal necrolysis: an international, multidisciplinary DELPHI-based consensus. Orphanet J Rare Dis. 2023;18:33. doi:10.1186/s13023-023-02631-7. 🔗 https://ojrd.biomedcentral.com/articles/10.1186/s13023-023-02631-7

In this JEADV Takeaway, Dr. Stefania Guida takes you through "Sex disparities in melanoma stage, recurrence and mortality: A Danish cohort study, 2004 to 2024" by J. E. Lyngstrand et al., published in the September 2026 issue of JEADV. The full article is available here: https://doi.org/10.1111/jdv.70180

Join Prof. Carle Paul as he presents his selection of Editor’s Picks from the September 2026 issue:  Dose reduction of biologics in psoriasis: giving more freedom to patients Litifilimab for cutaneous lupus erythematosus Managing high impact-site psoriasis: an oral IL-23 Receptor inhibitor on the menu Comorbidities influence treatment response to immune checkpoint inhibitors in squamous-cell carcinoma Read the Editor's Picks here: https://doi.org/10.1111/jdv.70607

In this episode of the EADV Podcast, held on behalf of the EADV Melanoma Task Force, Prof. Monika Arenbergerova is joined by Prof. Zoe Apalla and Prof. Aimilios Lallas to discuss the central role dermoscopy continues to play in melanoma diagnosis. The conversation opens with the newly published International Dermoscopy Society consensus recommendations for the management of lentigo maligna, exploring how dermoscopy and reflectance confocal microscopy guide diagnosis, lesion mapping, and monitoring of treatments such as topical immunotherapy alongside surgery. Together, they discuss the drivers behind melanoma's rising global incidence, striking differences in incidence and access to care across regions, and practical advice for clinicians building their dermoscopy skills, including the common pitfalls facing young dermatologists. The conversation also touches on how AI-powered digital biomarkers build on dermoscopy to help predict prognosis, and how each guest weighs sensitivity against specificity when deciding whether to biopsy. The episode closes with both speakers agreeing on what matters most for improving outcomes: faster access to specialists and earlier diagnosis of melanoma.   References: International Dermoscopy Society Consensus Recommendations for the Management of Lentigo Maligna (2026) Forsea AM, et al. International Dermoscopy Society consensus recommendations for the management of lentigo maligna. J Eur Acad Dermatol Venereol. 2026. doi:10.1111/jdv.70406. 🔗 https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.70406  

In this JEADV Takeaway, Dr. Prajwal Pudasaini takes you through "Addiction and chronic skin diseases: A Pan-European study on prevalence, associations and patient impact" by Ziehfreund S et al., published in the August 2026 issue of JEADV. The full article is available here: https://doi.org/10.1111/jdv.70245