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Dr Louise Fets @louise_fets discusses drugs and how membrane transporters mediate drug uptake with Eliano Dos Santos  and Sijia Yu. Dr Fets discusses her research on how this intersects with cancer metabolism.Read more about this episode's featured Publications of the Month a review on transcriptional enhancers and their interaction with genes and a publication on searching for genes related to COVID-19 susceptibility by postdoc Dr Helen Ray-Jones. 10.1007/s00018-021-03903-w & 10.3389/fgene.2021.745672.Together Dr Helen Ray-Jones and Dr Louise Fets discuss alternative therapies and why they have been marketed so heavily as treatments for COVID-19.
The Germline

The Germline

2021-09-3057:16

Julia Needham and  Ediem Al-jibury discuss science with Dr Harry Leitch and Adam McDermott Rouse.  Dr Leitch discusses his clinical practise,  the germline, pluripotency and the ways in which primordial germ cells can malfunction, causing cancers and  infertility. Should we edit the germline? Together he and Adam address this question in our segment Otoscope-Autoclave.Read more about this episode's publication of the month on studying the mode of action of insecticides and anthelmintic in worms from Adam McDermott Rouse here:   doi: 10.15252/msb.202110267.This episode was produced by the PhD students  Imanol Duran,  Julia Needham and  Ediem Al-jibury . Supported by the GECo team at the LMS MRC and Imperial Graduate School funding. 
Alice Brown and Saul Moore discuss the evolution molecular systems with Dr Tobias Warnecke and Dr Antoine Hocher. Dr Warnecke discusses the similarities and differences of key molecular systems across a range of organisms. And have we stopped evolving? Together he and Dr Hocher address this question in our segment Otoscope-Autoclave. Read more about this episode's featured Publication of the Month  by postdoc Dr Antoine Hocher from Dr Warnecke’s lab here: https://doi.org/10.1101/2021.07.08.451601 .This episode was produced by the PhD students Romain Strock,  Saul Moore and Alice Brown. Supported by the GECo team at the LMS MRC and Imperial Graduate School funding. 
Virinder Reen and Sherry Cheriyamkunel speak to Dr Alexis Barr and Dr Dounia Djeghloul about their work studying the cell cycle. Dr Barr discusses how cells make decisions on cell cycle entry and why this is important for cancer. Together she and Dr Djeghloul bust some common cancer myths in our segment Otoscope-Autoclave.  Read more about this episode's featured Publication of the Month a method for purifying proteins bound to mitotic DNA by postdoc Dr Dounia Djeghloul from Dame Amanda Fisher’s lab here: https://doi.org/10.1038/s41467-020-17823-z.This episode was produced by the PhD students Virinder Reen, Monica Della Rosa and Sherry Cheriyamkunel . Supported by the GECo team at the LMS MRC and Imperial Graduate School funding. 
Ediem Al-jibury and Julia Needham speak to Prof. Juanma Vaquerizas and Dr Fabio D'orazio about their careers, epigenetics through development and computational simulations to replace experiments. Publication of the Month by Dr Fabio D'orazio: https://doi.org/10.1016/j.devcel.2021.02.007
Genes and behaviour

Genes and behaviour

2021-05-3159:22

Radina Georgieva and Macia Sureda Vives talk with Dr. Andre Brown about using behaviour for high-throughput genetic and pharmacological screening. Find out more: https://tierpsy.com/Publication of the Month by Eliano dos Santos: https://doi.org/10.1016/j.cmet.2020.02.016
Schizophrenia

Schizophrenia

2021-04-3049:45

Eliano dos Santos and Saul Moore talk with Prof. Oliver Howes about schizophrenia, mental health, and the psychology behind conspiracy theories. Publication of the Month by Katie Stevens: https://doi.org/10.1073/pnas.2007056117
Sex, guts and flies

Sex, guts and flies

2021-03-3141:53

Eliano dos Santos and Sijia Yu talk with Prof. Irene Miguel Aliaga about sex differences in fly physiology and in careers. Publication of the Month by Ellis Chika Onwordi: https://doi.org/10.1038/s41467-019-14122-0
Eren Akademir, Macia Sureda Vives and Manos Stylianakis talk with Prof. Richard Festenstein about Friedreich's ataxia, precision medicine and genetic determinism. Publication of the Month by Matt Newton: https://doi.org/10.1038/s41594-019-0188-z
Radina Georgieva and Saul Moore talk with Dr. Peter Sarkies about evolution, epigenetics, transposable elements and gene editing in humans. Publication of the Month by Vassili Kuzmartsev: https://doi.org/10.1534/genetics.120.303028
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