Health & Veritas

Howie and Harlan are joined by Lee Schwamm, associate dean for digital strategy and transformation for Yale School of Medicine and chief digital health officer for Yale New Haven Health System, to discuss how AI and other digital tools can be part of fixing a broken healthcare system. Harlan reports on lightly regulated compounding pharmacies producing anti-obesity drugs; Howie gives an update on efforts by the FDA and CDC to fight bird flu. Links: "2023 Paul Dudley White Award: Dr. Lee Schwamm" Yale School of Medicine | Lisa Leffert, MD Health & Veritas | Dr. Lisa Leffert: Leading in Anesthesiology Testimony Prepared by Dr. Lee Schwamm Submitted to the House Committee on Energy and Commerce Subcommittee on Heath "Ambient AI Is Here, And We Are Blissfully Unaware Of It" "Yale New Haven Health to provide AI-driven clinical documentation" "Abridge, Mayo Clinic, And Epic Collaborate To Develop An Integrated Artificial Intelligence Documentation Solution For Nurses" "Are You Sure Your Ozempic Is Real? Fakes Are on the Rise." "Bill on Drug Compounding Clears Congress a Year After a Meningitis Outbreak" CDC | H5 Bird Flu: Current Situation "Is Bird Flu Spreading Widely to Farm Workers? A Small Study Offers Some Reassurance" Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Joshua Sharfstein, a longtime public health official in federal, state, and local government, to discuss the state of the opioid epidemic, lessons from the COVID-19 vaccine rollout, and our readiness for a bird flu outbreak. Harlan reports on the summer surge in COVID-19; Howie remembers his mentor Gail Wilensky, a health economist who directed Medicaid and Medicare programs and led many other organizations over a 50-year career.  Links: COVID-19 Update CDC: COVID Data Tracker CDC: COVID-19 Current Wastewater Viral Activity Levels Map “What to Know About COVID FLiRT Variants” Joshua Sharfstein Joshua Sharfstein: The Public Health Crisis Survival Guide: Leadership and Management in Trying Times Joshua Sharfstein: The Opioid Epidemic: What everyone needs to know” “How Can Over-the-Counter Naloxone Prevent Opioid Overdose Deaths?” CDC: H5 Bird Flu: Current Situation“Millions of US Children Experience Range of Long COVID Effects” Joshua Sharfstein: “The Role for Policy in AI-Assisted Medical Diagnosis”“External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients” “Epic’s overhaul of a flawed algorithm shows why AI oversight is a life-or-death issue” Podcast: “Baltimore cut infant mortality and helped moms thrive, too”Remembering Gail Wilensky “In Remembrance Of Gail Wilensky” “Gail Wilensky, Former CMS Administrator, Dies at 81” “In Memoriam: Gail Wilensky, Renowned Health Economist & NORC Trustee”Gail Wilensky: “The Health Care Quality Improvement Initiative” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Kate Goodrich, chief medical officer for Humana and a former Medicare staffer, to discuss the improvements in care and outcomes that result when providers are paid for each patient, not each service. Harlan looks at the challenge of payment for AI-based diagnostic tools; Howie asks if free tuition at Johns Hopkins medical school will address the real problems in medical education.  Links: AI Diagnostic Tools “Tempus Receives U.S. FDA 510(k) Clearance for Tempus ECG-AF, an AI-based Algorithm that Identifies Patients at Increased Risk of AFib” “Ensight-Ai Awarded Fda's Breakthrough Device Designation For Their Ecgvision-Ttr© Technology For Early Detection Of Attr-Cardiomyopathy Image” The Cardiovascular Workforce Crisis: Navigating the Present, Planning for the Future “American Medical Association Grants PLA Code to Tempus Algorithmic Test, PurISTSM” Kate Goodrich Humana: Value Based Care Report Centers for Medicare & Medicaid Services: Value Based Care “Medicare Spending on Ozempic and Other GLP-1s Is Skyrocketing” Free Tuition at Johns Hopkins “Bloomberg gives $1 billion to Hopkins to make tuition free for most medical students” Johns Hopkins School Of Medicine: Tuition And Financial Aid “Free med school tuition won’t solve the shortage of primary care physicians” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Timothy Westmoreland to discuss his long career in health policy and law, and the far-reaching consequences of the Supreme Court decision overturning Chevron deference. Harlan looks at President Joe Biden's debate struggles; Howie reports on the many healthcare-related Supreme Court decisions.  Links: The Presidential Debate Harlan Krumholz: “Did Cold Medications Affect Biden's Debate Performance?” CNN Presidential Debate: President Joe Biden and former President Donald Trump Press Briefing by Press Secretary Karine Jean-Pierre, July 2, 2024 “Biden's Evolving Reasons for His Bad Debate: A Cold, Too Much Prep, Not Feeling Great and Jet Lag” Timothy Westmoreland Timothy Westmoreland: “Henry Waxman, the Unsung Hero in the Fight Against AIDS” “LGBTQ History Month: The early days of America's AIDS crisis” Cornell Law School Legal Information Institute: Chevron deference Ballotpedia: Skidmore deference “How the Chevron case has roiled U.S. healthcare agencies”  SCOTUSblog: Corner Post, Inc. v. Board of Governors of the Federal Reserve System “Supreme Court appears likely to allow abortion drug to remain available” The Supreme Court “Implications for Public Health Regulation if Chevron Deference Is Overturned” Supreme Court opinion: Murthy, Surgeon General, et al. v. Missouri et al SCOTUSblog: Food and Drug Administration v. Alliance for Hippocratic Medicine Cornell Law School Legal Information Institute: Moyle v. United States Supreme Court of the United States Health & Veritas Ep. 77: Megan Ranney: What’s Next for Public Health? Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan catch up on healthcare headlines, including the politics of treating gun violence as a public health crisis, the growing evidence for the dangers of artificial sweeteners, and the latest on the bird flu outbreak. Links: Aspen Ideas: Health 2024 Harlan Krumholz: “The Next Era of JACC” "First Issue of JACC Debuts Under Harlan M. Krumholz" "U.S. clinical trials begin for twice-yearly HIV prevention injection" UNAIDS: 2023 Fact Sheet Rush University System: Dr. Omar B. Lateef "Rush Signs on as First Partner for Local Laundry Service" “Health Equity as a System Strategy: The Rush University Medical Center Framework” "Surgeon General Declares Gun Violence a Public Health Crisis" Surgeon General’s Advisory on Firearm Violence "Surgeon General: Why I’m Calling for a Warning Label on Social Media Platforms" “Patient Navigation for Lung Cancer Screening at a Health Care for the Homeless Program A Randomized Clinical Trial” Vinay Prasad: “CT screening for lung cancer for homeless people: the new JAMA IM paper” Supreme Court: Murthy v. Missouri Opinion "US supreme court allows government to request removal of misinformation on social media" Harlan Krumholz: “Why One Cardiologist Has Drunk His Last Diet Soda" “Xylitol is prothrombotic and associated with cardiovascular risk” "Is Xylitol Dangerous?" CDC: A(H5N1) Bird Flu Response Update June 21, 2024 "Michigan stands out for its aggressive bird flu response. Will other states follow its lead?" "Finland to offer bird flu vaccinations to at-risk residents in a world first" Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Lisa Suter, a rheumatologist and the senior director of the Quality Measurement Program at Yale’s Center for Outcomes Research & Evaluation. Harlan reflects on the meaning of Juneteenth and reports on a Yale-led report card on health equity; Howie comments on Surgeon General Vivek Murthy’s call for warning labels on social media.  Links: Juneteenth National Museum of African American History & Culture: Juneteenth Harlan Krumholz: “Excess Cardiovascular Mortality Among Black Americans 2000-2022: A JACC Report Card” “JACC Report Card Highlights Inequities in CV Care, Death Rates” Harlan Krumholz: “Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020” Lisa Suter Center for Outcomes Research and Evaluation National Institute of Arthritis and Musculoskeletal and Skin Disease: Arthritis Lisa Suter: “Medical Decision Making in Patients With Knee Pain, Meniscal Tear, and Osteoarthritis” Lisa Suter: “Projecting Lifetime Risk of Symptomatic Knee Osteoarthritis and Total Knee Replacement in Individuals Sustaining a Complete Anterior Cruciate Ligament Tear in Early Adulthood” “Voices of DEI: Lisa Suter, MD” Harlan Krumholz: “Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study” Harlan Krumholz: “Association of Racial and Socioeconomic Disparities With Outcomes Among Patients Hospitalized With Acute Myocardial Infarction, Heart Failure, and Pneumonia An Analysis of Within- and Between-Hospital Variation” The Surgeon General on Social Media  “Surgeon General: Why I’m Calling for a Warning Label on Social Media Platforms” “Social Media and Youth Mental Health: The U.S Surgeon General’s Advisory” Kids Online Safety Act: Senator Richard Blumenthal Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Anna Reisman, a physician and writer who leads Yale’s Program for Humanities in Medicine. They discuss the gaps in care she encountered when her developmentally disabled sister was diagnosed with cancer, and her work reviewing the “dude wall” of portraits at Yale Medical School. Harlan asks what we’ve gained from a new definition of long COVID; Howie provides an update on the spread of the H5N1 bird flu.  Links: Defining Long COVID “Federal Government, Clinicians, Employers, and Others Should Adopt New Definition for Long COVID to Aid in Consistent Diagnosis, Documentation, and Treatment” National Academies: A Long COVID Definition WHO: Post COVID-19 condition (Long COVID) Anna Reisman U.S. News: Yale University department rankings Wikipedia: The Magic Mountain Anna Reisman: “A doctor’s life, chronicled” “Life on wheels” (Yale School of Medicine article on the documentary Rolling) Anna Reisman: “Standard of Care” “Academic Science Rethinks All-Too-White 'Dude Walls' Of Honor” Wikipedia: Stanhope Bayne-Jones “In Memoriam: Marjorie Rosenthal, MD '95, MPH 1967–2020” “Yale Internal Medicine Residency Writers’ Workshop celebrates 20th anniversary”. Bird Flu FDA: Updates on Highly Pathogenic Avian Influenza (HPAI) “CDC Reports A(H5N1) Ferret Study Results” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Mitesh Rao, co-founder and CEO of OMNY Health, joins Howie and Harlan to discuss his entrepreneurial journey and how his company is creating a common layer of data connecting healthcare providers and researchers. Harlan reports on a study showing how many lives could be saved by improving quality of care; Howie reflects on the health consequences that have accompanied the legalization of cannabis.  Links: Quality and Lives Saved “The business case for quality: estimating lives saved and harms avoided in a value-based purchasing model” The CMS Innovation Center NCQA: Hedis Measures South Park: “Navigating the American Healthcare System” Mitesh Rao OMNY Health: Connect Data to Transform Lives “OMNY Health announces $17 Million Raise to Lead the Next Generation of Real-World Data-Driven Decision-Making and Collaboration Across Healthcare” Crunchbase: OMNY Health “How Venture Capital Works” UK Biobank: Enabling Scientific Discoveries that Improve Human Health “The Robert Wood Johnson Clinical Scholars Program: Four Decades of Training Physicians as Agents of Change” HIPAA: Health Information Privacy Yale Innovation Summit Cannabis and Health “Justice Department Submits Proposed Regulation to Reschedule Marijuana” “Changes in self-reported cannabis use in the United States from 1979 to 2022” Cannabinoid Hyperemesis Syndrome “Cannabis and Psychosis: Recent Epidemiological Findings Continuing the ‘Causality Debate’” “High-potency marijuana highlights the risk of cannabis-induced psychiatric disorders” Marijuana Addiction Facts: Is Marijuana Addictive? Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

A special episode recorded at the Yale Innovation Summit, which brings together entrepreneurs and investors in the arts, biotech, climate, health, and tech. Howie and Harlan are joined by Josh Geballe, managing director of Yale Ventures, which hosts the summit; Mary Ann Melnick, site head at Biolabs New Haven; and Lee Schwamm, chief digital health officer at Yale New Haven Health System.  Links: Watch the event on YouTube. Yale Ventures: Yale Innovation Summit State of Connecticut: “Governor Lamont Announces Creation of the Innovation Clusters Program To Support Growth in Cutting-Edge Industries” Yale Ventures: Venture Lab BioLabs New Haven The Provost’s Committee on Conflict of Interest “Novel BioLaunch program to train New Haven residents for careers in biotech” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Chima Ndumele of the Yale School of Public Health to discuss his research on structural changes to Medicaid that could keep vulnerable populations healthier. Harlan reports on the remarkable abilities of Google's latest medicine-focused AI; Howie reflects on a study showing the impact of race-neutral measures of lung function.  Links: AI and Medicine “Capabilities of Gemini Models in Medicine” Medicaid Medicaid.gov “10 Things to Know About Medicaid” Supplemental Nutrition Assistance Program (SNAP) “Long-Term Stability of Coverage Among Michigan Medicaid Beneficiaries: A Cohort Study” “Unwinding And The Medicaid Undercount: Millions Enrolled In Medicaid During The Pandemic Thought They Were Uninsured” Chima Ndumele: “Variation in Health Outcomes: The Role of Spending on Social Services, Public Health, and Health Care, 2000–09” Chima Ndumele: “In Medicaid Managed Care Networks, Care Is Highly Concentrated Among A Small Percentage Of Physicians” “N.C. developing plan to improve Medicaid participants’ job prospects” “Yale School of Public Health Graduates Urged to Adopt a “Healthy Disregard for the Impossible” Race and Lung Function “Implications of Race Adjustment in Lung-Function Equations” Harlan Krumholz: “Association of Racial and Socioeconomic Disparities with Outcomes among Patients Hospitalized with Acute Myocardial Infarction, Heart Failure, and Pneumonia. An Analysis of Within- and Between-Hospital Variation” “Q&A: Harlan Krumholz on hospital readmissions” Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit. Watch live on YouTube. Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Ruth Katz, executive director of the Aspen Institute’s Health, Medicine & Society Program and a former Capitol Hill staffer, to discuss her work on the Affordable Care Act and other major healthcare laws. Harlan reflects on a study showing that using different analytical approaches to the same data can lead to a wide range of conclusions; Howie reports on a wave of dangerous infections caused by stem cell treatments at clinics in Mexico.  Links: Reproducible Research “Grilling the data: application of specification curve analysis to red meat and all-cause mortality” “Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results” Ruth Katz “Reflecting on Past Accomplishments to Make History Moving Forward: The NIH Revitalization Act of 1993 and the New Office of Autoimmune Disease Research “Thousands Believe Covid Vaccines Harmed Them. Is Anyone Listening?” National Vaccine Injury Compensation Program Health Resources and Services Administration: Vaccine Injury Table “Brilliant Minds. Bold Approaches. Better Health. Aspen Ideas: Health Announces Programming Themes for 2024” Medical Tourism and Stem Cell Treatments “Stem cell injections in Mexico can be hazardous. Report identifies US victims” CDC: Medical Tourism Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit Watch live on YouTube Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Greg Licholai, a Yale SOM lecturer and biotech entrepreneur, to discuss his career and his work at the contract research organization ICON, which performs clinical trials for pharmaceutical companies. Harlan reports on new research illustrating the dangerous consequences of asking patients to share the costs of life-saving drugs; Howie provides the good news and the bad news from the annual Medicare Trustees Report.  Links: Cost-Sharing and Mortality “The Health Costs Of Cost-Sharing” “The Boys of January” Greg Licholai ICON plc Greg Licholai in Forbes Boston Children's Hospital: Sickle Cell Disease The State of the Medicare Trust Fund Medicare: Coverage Gap 2024 Medicare Trustees Report KFF: FAQs on Medicare Financing and Trust Fund Solvency KFF: What to Know about Medicare Spending and Financing Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit Watch live on YouTube Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan discuss health and healthcare headlines. From flatlining telehealth to Walmart closing retail clinics to months-long waits for healthcare appointments, they try to untangle the challenges in delivering healthcare. Also considered, H5N1 bird flu increasing the risks of drinking unpasteurized milk, promising research on open-source moderation of misinformation on social media. Links: Yale Repertory Theater | The Far Country CDC | H5N1 “US bird flu outbreak spreads to chickens, cattle, raises concerns over human infections” “Raw Milk Is Being Legalized in More States. Is It Safe?” “Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome“ “Long-time Teladoc leader departs as virtual care provider struggles with post-COVID tumble” “Teladoc sinks $13.7B loss in 2022 tied to plummeting value of Livongo acquisition” “Optum layoffs: naviHealth CEO out; Virtual care business shuttered” Connecticut | Certificate of Needs Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation “Walmart is closing down its health centers. What’s that mean for Amazon, Walgreens and CVS?” “Walgreens narrows profit outlook for 2024, takes $6B hit in Q2 from VillageMD investment” “Why It Takes Forever to Get a Doctor’s Appointment” Yale Innovation Summit 2024 Link for the Health & Veritas Livestream at the Yale Innovation Summit Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Arthur Caplan, Drs. William F. and Virginia Connolly Mitty Professor of Bioethics and founding head of the division of medical ethics at NYU Grossman School of Medicine, to discuss the ethical failings of the pharmaceutical industry and how a community-focused ethos prioritizing justice and protection of the vulnerable would have reshaped the COVID response. Harlan reports on developments in synthetic proteins. Howie recognizes World Malaria Day. Links: Division of Medical Ethics: NYU Langone “‘You’ve got bad blood’: The horror of the Tuskegee syphilis experiment” “When Evil Intrudes” “Surgeons Perform World’s First Combined Heart Pump And Pig Kidney Transplant—Latest Breakthrough Involving Pig Organ” “Biden trolls Trump on injecting bleach anniversary” Frequently Asked Questions on Oregon’s Death With Dignity Act (DWDA) “A quiet revolution in organ transplant ethics” Center for Healthcare Ethics: The Provider-Patient Relationship “Ex-Stanford President’s AI Drug Startup Pulls In $1 Billion in Commitments” “Protein wrangler, serial entrepreneur, and community builder: Inside David Baker’s brain” Baker Lab: Home Page “Atomically accurate de novo design of single-domain antibodies” National Cancer Institute: Definition of a Monoclonal Antibody Malaria: World Health Organization  CDC: Malaria’s Impact Worldwide UNICEF: Ten things you didn’t know about malaria Yale Innovation Summit 2024 Link for the Health & Veritas Livestream at the Yale Innovation Summit Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Scott Berkowitz ’03, cardiologist and chief population health officer at Johns Hopkins Medicine, to discuss the necessity of moving from fee-for-service to value-based care delivery to improve outcomes for all. Harlan highlights the dangers of misinformation about Ivermectin. Howie reports on the potential conflicts of interest created by device manufacturers’ payments to cardiologists. Links: Johns Hopkins Medicine: Home Johns Hopkins Community Health Partnership “Association of a Care Coordination Model With Health Care Costs and Utilization” “Planning for the Future of Population Health: The Johns Hopkins Medicine Experience” “Califf’s long day on Capitol Hill” “The FDA Deleted Its Viral Ivermectin Tweets. Now There’s Even More Misinformation.” “Philly Nonprofit Awarded $48 Million to Apply AI in Search for New Uses for Approved Drugs Posted on March 12, 2024” “Effect of Early Treatment with Ivermectin among Patients with Covid-19” “Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19” “Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19” “Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype” Ivermectin and Covid “FDA settles lawsuit over ivermectin content that doctors claimed harmed their practice” “Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices” “Impact of Industry Payments on Prescribing Patterns for Tumor Necrosis Factor Inhibitors Among Medicare Beneficiaries” Yale Innovation Summit 2024 Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Atheendar Venkataramani, a physician, health economist, and director of the Perelman School of Medicine’s Opportunity for Health Lab, to discuss the powerful role of economic opportunity in population health outcomes. Harlan reports on two studies where treatments’ unexpected benefits leapt ahead of understanding why they work. Howie reflects on the business model of the pharma industry and the market reaction to anti-obesity drugs. Links: Opportunity for Health | Home “College Affirmative Action Bans and Smoking and Alcohol Use among Underrepresented Minority Adolescents in the United States: A Difference-in-differences Study” “Police Killings and Their Spillover Effects on the Mental Health of Black Americans: A Population-based, Quasi-experimental Study” “Officer-Involved Killings of Unarmed Black People and Racial Disparities in Sleep Health“ Behavioral Risk Factor Surveillance System | Home “Building Black Wealth — The Role of Health Systems in Closing the Gap“ KFF | Understanding Mergers Between Hospitals and Health Systems in Different Markets “In Hospitals, Affordable Housing Gets the Long-Term Investor It Needs” American College of Cardiology 73rd Annual Scientific Session & Expo  “Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes“ “Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial” “A Placebo-Controlled Trial of PCI for Stable Angina“ “Trial of Lixisenatide in Early Parkinson’s Disease“ “The Cream of The Crop: 5 Biotechs That Outrank Most Stocks” “How High Can Eli Lilly Stock Go? $1,000 A Share, One Analyst Says” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Kate McEvoy, executive director of the National Association of Medicaid Directors, to discuss the programs’ underappreciated advances in holistically addressing health, housing, and food security. Reflecting on the upcoming election, Harlan notes that facts matter, whether in medicine or politics. Howie reports on the dangers of glyoxylic acid in hair straightening products. Links: “Trump Leads Biden in Six of Seven Swing States, WSJ Poll Finds” “Takeover: Hitler’s Final Rise to Power” “The Forgotten History of Hitler’s Establishment Enablers” The Future of Health Policy in a Partisan United States “Netflix blockbuster ‘3 Body Problem’ divides opinion and sparks nationalist anger in China” “The Future of American Democracy Depends on Improving U.S. Health” Wikipedia | Glyoxylic acid Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid American Cancer Society | Formaldehyde and Cancer Risk Kaiser Family Foundation | 10 Things to Know About the Unwinding of the Medicaid Continuous Enrollment Provision Kaiser Family Foundation | Medicaid Postpartum Coverage Extension Tracker CMS | NHE Fact Sheet Moral Injuries in Healthcare Workers: What Causes Them and What to Do About Them? NCDHHS | Healthy Opportunities Pilots HealthTech4Medicaid | About Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Margo Harrison, an OB-GYN and femtech entrepreneur, to discuss how innovative solutions to women’s health problems offer deeper understanding and expanded choices. Harlan and Howie each offer a caveat emptor for lightly regulated, unproven supplements and treatments such as Prevagen and hydration spas. Links: “Prevagen Review: A Word of Caution” “Prevagen®: Analysis of Clinical Evidence and Its Designation as a ‘#1 Pharmacist Recommended Brand’” “NY Jury Rules Some Claims About Prevagen Are Misleading” “Effects of a Supplement Containing Apoaequorin on Verbal Learning in Older Adults in the Community” Mate Fertility: Home Dahlia Ventures Margo Harrison, MD: Assistant Adjoint Professor, OB-GYN-Basic Repro Science Margo Harrison: LinkedIn “Use of Cesarean Birth at Mizan Tepi University Teaching Hospital, Mizan Aman, Ethiopia” “Postpartum Contraceptive Use Among Denver-Based Adolescents and Young Adults: Association with Subsequent Repeat Delivery” “Warnings grow about risky IV drips and injections at unregulated med spas” “FDA highlights concerns with compounding of drug products by medical offices and clinics under insanitary conditions” “Drip bar: Should you get an IV on demand?” “Are Your Therapies FDA Compliant?”

Howie and Harlan are joined by Yale health economist Zack Cooper to discuss his work on surprise medical bills and the impact of high healthcare costs on households, wages, and the economy. Harlan reports on Hippocratic AI’s efforts to develop AI nurses. Howie looks at the global effort to eradicate tuberculosis. Links: “Hippocratic AI banks $53M backed by General Catalyst, a16z, Memorial Hermann, UHS and other health systems” “Polaris: A Safety-focused LLM Constellation Architecture for Healthcare” Yale | Eli Whitney Students Program Touching the Dragon: And Other Techniques for Surviving Life’s Wars The Price Ain’t Right? Hospital Prices and Health Spending on the Privately Insured “Costs Can Go Up Fast When E.R. Is in Network but the Doctors Are Not” “Bankrupt Envision Healthcare approved to split in two, cut debt” “The Company Behind Many Surprise Emergency Room Bills” Surprise! Out-of-Network Billing for Emergency Care in the United States “Medical LLM developer Hippocratic AI gets $53M at $500 valuation” The Breakthrough of Large Language Models Release for Medical Applications: 1-Year Timeline and Perspectives World Health Organization | World Tuberculosis Day Partners In Health | Tuberculosis “WHO urges investments for the scale up of tuberculosis screening and preventive treatment” “The latest twist in John Green’s anti-tuberculosis story: working with governments” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Robert Alpern, a Yale nephrologist and the former dean of the Yale School of Medicine, to discuss the importance of a fiscal base for enabling a medical school to deliver top-quality training, research, and clinical care. Harlan asks whether widespread norovirus is a reason to call it quits on shaking hands. Howie reports on a study of the increased mortality among those with ADHD. “Nephrologist Robert Alpern Named Dean of Yale School of Medicine” “UT Southwestern: From Army” Shacks to Research Elites” “National Clinician Scholars Program” “A ‘bittersweet’ end: Historic merger creates one of the nation’s largest hospitals” “Yale New Haven Health: Smilow Cancer Hospital” “Alpern will not seek a fourth term as School of Medicine dean” “Alpern to Step Down After Current Term as Dean” “Cleveland Clinic: Norovirus” “State of Affairs: March 12: Flu, measles, norovirus, and interesting Pew results” “Norovirus has entered the chat” “ADHD Pharmacotherapy and Mortality in Individuals With ADHD” “Overdiagnosis of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents” “Racial Disparities in Diagnosis of Attention-Deficit/Hyperactivity Disorder in a US National Birth Cohort” “Longitudinal associations between digital media use and ADHD symptoms in children and adolescents: a systematic literature review” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.