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Health & Veritas

Author: Yale School of Management

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Howard Forman and Harlan Krumholz, two Yale physician-professors, discuss the latest news and ideas in healthcare and seek out the truth amid the noise. Produced with the Yale School of Management and the Yale School of Public Health. New episodes are available every Thursday.
132 Episodes
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Howie and Harlan are joined by Chima Ndumele of the Yale School of Public Health to discuss his research on structural changes to Medicaid that could keep vulnerable populations healthier. Harlan reports on the remarkable abilities of Google's latest medicine-focused AI; Howie reflects on a study showing the impact of race-neutral measures of lung function.  Links: AI and Medicine “Capabilities of Gemini Models in Medicine” Medicaid Medicaid.gov “10 Things to Know About Medicaid” Supplemental Nutrition Assistance Program (SNAP) “Long-Term Stability of Coverage Among Michigan Medicaid Beneficiaries: A Cohort Study” “Unwinding And The Medicaid Undercount: Millions Enrolled In Medicaid During The Pandemic Thought They Were Uninsured” Chima Ndumele: “Variation in Health Outcomes: The Role of Spending on Social Services, Public Health, and Health Care, 2000–09” Chima Ndumele: “In Medicaid Managed Care Networks, Care Is Highly Concentrated Among A Small Percentage Of Physicians” “N.C. developing plan to improve Medicaid participants’ job prospects” “Yale School of Public Health Graduates Urged to Adopt a “Healthy Disregard for the Impossible” Race and Lung Function “Implications of Race Adjustment in Lung-Function Equations” Harlan Krumholz: “Association of Racial and Socioeconomic Disparities with Outcomes among Patients Hospitalized with Acute Myocardial Infarction, Heart Failure, and Pneumonia. An Analysis of Within- and Between-Hospital Variation” “Q&A: Harlan Krumholz on hospital readmissions” Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit. Watch live on YouTube. Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Ruth Katz, executive director of the Aspen Institute’s Health, Medicine & Society Program and a former Capitol Hill staffer, to discuss her work on the Affordable Care Act and other major healthcare laws. Harlan reflects on a study showing that using different analytical approaches to the same data can lead to a wide range of conclusions; Howie reports on a wave of dangerous infections caused by stem cell treatments at clinics in Mexico.  Links: Reproducible Research “Grilling the data: application of specification curve analysis to red meat and all-cause mortality” “Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results” Ruth Katz “Reflecting on Past Accomplishments to Make History Moving Forward: The NIH Revitalization Act of 1993 and the New Office of Autoimmune Disease Research “Thousands Believe Covid Vaccines Harmed Them. Is Anyone Listening?” National Vaccine Injury Compensation Program Health Resources and Services Administration: Vaccine Injury Table “Brilliant Minds. Bold Approaches. Better Health. Aspen Ideas: Health Announces Programming Themes for 2024” Medical Tourism and Stem Cell Treatments “Stem cell injections in Mexico can be hazardous. Report identifies US victims” CDC: Medical Tourism Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit Watch live on YouTube Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Greg Licholai, a Yale SOM lecturer and biotech entrepreneur, to discuss his career and his work at the contract research organization ICON, which performs clinical trials for pharmaceutical companies. Harlan reports on new research illustrating the dangerous consequences of asking patients to share the costs of life-saving drugs; Howie provides the good news and the bad news from the annual Medicare Trustees Report.  Links: Cost-Sharing and Mortality “The Health Costs Of Cost-Sharing” “The Boys of January” Greg Licholai ICON plc Greg Licholai in Forbes Boston Children's Hospital: Sickle Cell Disease The State of the Medicare Trust Fund Medicare: Coverage Gap 2024 Medicare Trustees Report KFF: FAQs on Medicare Financing and Trust Fund Solvency KFF: What to Know about Medicare Spending and Financing Health & Veritas Live on May 30 Join Howie and Harlan in person at the Yale Innovation Summit Watch live on YouTube Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan discuss health and healthcare headlines. From flatlining telehealth to Walmart closing retail clinics to months-long waits for healthcare appointments, they try to untangle the challenges in delivering healthcare. Also considered, H5N1 bird flu increasing the risks of drinking unpasteurized milk, promising research on open-source moderation of misinformation on social media. Links: Yale Repertory Theater | The Far Country CDC | H5N1 “US bird flu outbreak spreads to chickens, cattle, raises concerns over human infections” “Raw Milk Is Being Legalized in More States. Is It Safe?” “Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome“ “Long-time Teladoc leader departs as virtual care provider struggles with post-COVID tumble” “Teladoc sinks $13.7B loss in 2022 tied to plummeting value of Livongo acquisition” “Optum layoffs: naviHealth CEO out; Virtual care business shuttered” Connecticut | Certificate of Needs Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation “Walmart is closing down its health centers. What’s that mean for Amazon, Walgreens and CVS?” “Walgreens narrows profit outlook for 2024, takes $6B hit in Q2 from VillageMD investment” “Why It Takes Forever to Get a Doctor’s Appointment” Yale Innovation Summit 2024 Link for the Health & Veritas Livestream at the Yale Innovation Summit Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Arthur Caplan, Drs. William F. and Virginia Connolly Mitty Professor of Bioethics and founding head of the division of medical ethics at NYU Grossman School of Medicine, to discuss the ethical failings of the pharmaceutical industry and how a community-focused ethos prioritizing justice and protection of the vulnerable would have reshaped the COVID response. Harlan reports on developments in synthetic proteins. Howie recognizes World Malaria Day. Links: Division of Medical Ethics: NYU Langone “‘You’ve got bad blood’: The horror of the Tuskegee syphilis experiment” “When Evil Intrudes” “Surgeons Perform World’s First Combined Heart Pump And Pig Kidney Transplant—Latest Breakthrough Involving Pig Organ” “Biden trolls Trump on injecting bleach anniversary” Frequently Asked Questions on Oregon’s Death With Dignity Act (DWDA) “A quiet revolution in organ transplant ethics” Center for Healthcare Ethics: The Provider-Patient Relationship “Ex-Stanford President’s AI Drug Startup Pulls In $1 Billion in Commitments” “Protein wrangler, serial entrepreneur, and community builder: Inside David Baker’s brain” Baker Lab: Home Page “Atomically accurate de novo design of single-domain antibodies” National Cancer Institute: Definition of a Monoclonal Antibody Malaria: World Health Organization  CDC: Malaria’s Impact Worldwide UNICEF: Ten things you didn’t know about malaria Yale Innovation Summit 2024 Link for the Health & Veritas Livestream at the Yale Innovation Summit Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Scott Berkowitz ’03, cardiologist and chief population health officer at Johns Hopkins Medicine, to discuss the necessity of moving from fee-for-service to value-based care delivery to improve outcomes for all. Harlan highlights the dangers of misinformation about Ivermectin. Howie reports on the potential conflicts of interest created by device manufacturers’ payments to cardiologists. Links: Johns Hopkins Medicine: Home Johns Hopkins Community Health Partnership “Association of a Care Coordination Model With Health Care Costs and Utilization” “Planning for the Future of Population Health: The Johns Hopkins Medicine Experience” “Califf’s long day on Capitol Hill” “The FDA Deleted Its Viral Ivermectin Tweets. Now There’s Even More Misinformation.” “Philly Nonprofit Awarded $48 Million to Apply AI in Search for New Uses for Approved Drugs Posted on March 12, 2024” “Effect of Early Treatment with Ivermectin among Patients with Covid-19” “Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19” “Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19” “Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype” Ivermectin and Covid “FDA settles lawsuit over ivermectin content that doctors claimed harmed their practice” “Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices” “Impact of Industry Payments on Prescribing Patterns for Tumor Necrosis Factor Inhibitors Among Medicare Beneficiaries” Yale Innovation Summit 2024 Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Atheendar Venkataramani, a physician, health economist, and director of the Perelman School of Medicine’s Opportunity for Health Lab, to discuss the powerful role of economic opportunity in population health outcomes. Harlan reports on two studies where treatments’ unexpected benefits leapt ahead of understanding why they work. Howie reflects on the business model of the pharma industry and the market reaction to anti-obesity drugs. Links: Opportunity for Health | Home “College Affirmative Action Bans and Smoking and Alcohol Use among Underrepresented Minority Adolescents in the United States: A Difference-in-differences Study” “Police Killings and Their Spillover Effects on the Mental Health of Black Americans: A Population-based, Quasi-experimental Study” “Officer-Involved Killings of Unarmed Black People and Racial Disparities in Sleep Health“ Behavioral Risk Factor Surveillance System | Home “Building Black Wealth — The Role of Health Systems in Closing the Gap“ KFF | Understanding Mergers Between Hospitals and Health Systems in Different Markets “In Hospitals, Affordable Housing Gets the Long-Term Investor It Needs” American College of Cardiology 73rd Annual Scientific Session & Expo  “Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes“ “Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial” “A Placebo-Controlled Trial of PCI for Stable Angina“ “Trial of Lixisenatide in Early Parkinson’s Disease“ “The Cream of The Crop: 5 Biotechs That Outrank Most Stocks” “How High Can Eli Lilly Stock Go? $1,000 A Share, One Analyst Says” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Kate McEvoy, executive director of the National Association of Medicaid Directors, to discuss the programs’ underappreciated advances in holistically addressing health, housing, and food security. Reflecting on the upcoming election, Harlan notes that facts matter, whether in medicine or politics. Howie reports on the dangers of glyoxylic acid in hair straightening products. Links: “Trump Leads Biden in Six of Seven Swing States, WSJ Poll Finds” “Takeover: Hitler’s Final Rise to Power” “The Forgotten History of Hitler’s Establishment Enablers” The Future of Health Policy in a Partisan United States “Netflix blockbuster ‘3 Body Problem’ divides opinion and sparks nationalist anger in China” “The Future of American Democracy Depends on Improving U.S. Health” Wikipedia | Glyoxylic acid Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid American Cancer Society | Formaldehyde and Cancer Risk Kaiser Family Foundation | 10 Things to Know About the Unwinding of the Medicaid Continuous Enrollment Provision Kaiser Family Foundation | Medicaid Postpartum Coverage Extension Tracker CMS | NHE Fact Sheet Moral Injuries in Healthcare Workers: What Causes Them and What to Do About Them? NCDHHS | Healthy Opportunities Pilots HealthTech4Medicaid | About Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Margo Harrison, an OB-GYN and femtech entrepreneur, to discuss how innovative solutions to women’s health problems offer deeper understanding and expanded choices. Harlan and Howie each offer a caveat emptor for lightly regulated, unproven supplements and treatments such as Prevagen and hydration spas. Links: “Prevagen Review: A Word of Caution” “Prevagen®: Analysis of Clinical Evidence and Its Designation as a ‘#1 Pharmacist Recommended Brand’” “NY Jury Rules Some Claims About Prevagen Are Misleading” “Effects of a Supplement Containing Apoaequorin on Verbal Learning in Older Adults in the Community” Mate Fertility: Home Dahlia Ventures Margo Harrison, MD: Assistant Adjoint Professor, OB-GYN-Basic Repro Science Margo Harrison: LinkedIn “Use of Cesarean Birth at Mizan Tepi University Teaching Hospital, Mizan Aman, Ethiopia” “Postpartum Contraceptive Use Among Denver-Based Adolescents and Young Adults: Association with Subsequent Repeat Delivery” “Warnings grow about risky IV drips and injections at unregulated med spas” “FDA highlights concerns with compounding of drug products by medical offices and clinics under insanitary conditions” “Drip bar: Should you get an IV on demand?” “Are Your Therapies FDA Compliant?”
Howie and Harlan are joined by Yale health economist Zack Cooper to discuss his work on surprise medical bills and the impact of high healthcare costs on households, wages, and the economy. Harlan reports on Hippocratic AI’s efforts to develop AI nurses. Howie looks at the global effort to eradicate tuberculosis. Links: “Hippocratic AI banks $53M backed by General Catalyst, a16z, Memorial Hermann, UHS and other health systems” “Polaris: A Safety-focused LLM Constellation Architecture for Healthcare” Yale | Eli Whitney Students Program Touching the Dragon: And Other Techniques for Surviving Life’s Wars The Price Ain’t Right? Hospital Prices and Health Spending on the Privately Insured “Costs Can Go Up Fast When E.R. Is in Network but the Doctors Are Not” “Bankrupt Envision Healthcare approved to split in two, cut debt” “The Company Behind Many Surprise Emergency Room Bills” Surprise! Out-of-Network Billing for Emergency Care in the United States “Medical LLM developer Hippocratic AI gets $53M at $500 valuation” The Breakthrough of Large Language Models Release for Medical Applications: 1-Year Timeline and Perspectives World Health Organization | World Tuberculosis Day Partners In Health | Tuberculosis “WHO urges investments for the scale up of tuberculosis screening and preventive treatment” “The latest twist in John Green’s anti-tuberculosis story: working with governments” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Robert Alpern, a Yale nephrologist and the former dean of the Yale School of Medicine, to discuss the importance of a fiscal base for enabling a medical school to deliver top-quality training, research, and clinical care. Harlan asks whether widespread norovirus is a reason to call it quits on shaking hands. Howie reports on a study of the increased mortality among those with ADHD. “Nephrologist Robert Alpern Named Dean of Yale School of Medicine” “UT Southwestern: From Army” Shacks to Research Elites” “National Clinician Scholars Program” “A ‘bittersweet’ end: Historic merger creates one of the nation’s largest hospitals” “Yale New Haven Health: Smilow Cancer Hospital” “Alpern will not seek a fourth term as School of Medicine dean” “Alpern to Step Down After Current Term as Dean” “Cleveland Clinic: Norovirus” “State of Affairs: March 12: Flu, measles, norovirus, and interesting Pew results” “Norovirus has entered the chat” “ADHD Pharmacotherapy and Mortality in Individuals With ADHD” “Overdiagnosis of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents” “Racial Disparities in Diagnosis of Attention-Deficit/Hyperactivity Disorder in a US National Birth Cohort” “Longitudinal associations between digital media use and ADHD symptoms in children and adolescents: a systematic literature review” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Robert Rohrbaugh, professor of psychiatry and deputy dean for professionalism and leadership at the Yale School of Medicine, to discuss his work training doctors in antiracist practices and ensuring the wellbeing of clinicians during the pandemic. Harlan reports on the problematic history of medical journals promoting eugenics; Howie highlights a cyberattack that has paralyzed Change Healthcare, the country’s largest payments processing hub.  Links: Antiracist Documentation Practices — Shaping Clinical Encounters and Decision Making American Psychological Association | Implicit Bias “YSM Ranks #1 in U.S. News Survey for Psychiatry” COVID-19 Traumatic Disaster Appraisal and Stress Symptoms Among Health Care Workers Application of Artificial Intelligence on Psychological Interventions and Diagnosis: An Overview Is AI the Future of Mental Healthcare? ChatGPT outperforms humans in emotional awareness evaluations “Ridding the Race of His Defective Blood” — Eugenics in the Journal, 1906–1948 Problems Underlying Public Hospital Administration Wikipedia | Public Hospital Eugenics and Involuntary Sterilization: 1907–2015 “Cyberattack Paralyzes the Largest U.S. Health Care Payment System” “Physicians beg for relief amid Change Healthcare payment crisis” “Court Rejects Vertical Merger Challenge Brought by DOJ” “Aledade Takes Steps to Support Independent Primary Care Partners in Wake of Change Healthcare CyberAttack”
Howie and Harlan discuss health and healthcare headlines, including a cheating scandal that has led to the invalidation of hundreds of scores from Nepal on the U.S. Medical Licensing Examination, the problem of research that never sees the light of day, new anti-obesity medications, and Florida’s unorthodox approach to measles. Links: Standardized Testing “Cheated out of the American Dream” “MCAT scores and medical school success: Do they correlate?” ”Reducing Medical School Admissions Disparities in an Era of Legal Restrictions: Adjusting for Applicant Socioeconomic Disadvantage” “Medical School Admissions — A Movable Barrier to Ending Health Care Disparities?” “Yale Reinstates Standardized Test Score Requirement For Admissions” “New SAT Data Highlights the Deep Inequality at the Heart of American Education” Research at Universities Good Science Project: Stuart Buck “Why Are We Screwing Over Researchers Who Make Innovative Discoveries?” Intellectual Property: Ownership and Protection in a University Setting Measles in Florida “From COVID-19 to Measles, Florida’s War on Public Health” CDC: About Measles “Additional measles case reported at Florida elementary school as lawmaker urges public health emergency” Obesity Drugs “Heard on the Street: Viking Therapeutics Invades Eli Lilly’s Obesity Territory” Unreleased Research Data “The Ghost Research Haunting Nordic Medical Trials” “Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis” Harlan Krumholz: “What have we learnt from Vioxx?” A Transformative Gift “$1 Billion Donation Will Provide Free Tuition at a Bronx Medical School” IVF in Alabama The Alabama Supreme Court’s Ruling “Florida Suspends Bill to Protect ‘Unborn Child’ After I.V.F. Ruling” Johns Hopkins Bloomberg School of Public Health: The Alabama Supreme Court’s Ruling on Frozen Embryos Faculty for Yale Faculty for Yale “The Need For Institutional Neutrality At Universities” “Yale faculty sign letter addressed to Yale’s future president, affirms commitment to social justice” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Lucila Ohno-Machado, the Yale School of Medicine’s deputy dean for biomedical informatics. She explains how expanding use of data science, informatics, AI, and technology could enable doctors to spend more time with patients. Harlan celebrates mentorship while marking the death of Irwin Birnbaum, a mentor to many in his time as COO of the Yale Medical School and long after retiring. Howie discusses the mixed evidence from a study on vaping as a tool for helping cigarette smokers quit. Links: “Lucila Ohno-Machado, MD, PhD, MBA, Will Lead Biomedical Informatics and Data Science” “Lucila Ohno-Machado: Yale Medicine Profile” “Halıcıoğlu Data Science Center” “2024 AI in Medicine Symposium at Yale School of Medicine” “Doctors Vs. ChatGPT: Which Is More Empathetic?” “Irwin M. Birnbaum Obituary” “What is a mentor?” “A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy” “Episode 78, Health and Veritas: Elizabeth Arleo: Advice for Working Mothers from a Women’s Health Specialist”
Howie and Harlan are joined by Farzad Mostashari, co-founder and CEO of Aledade, an "accountable care organization" that seeks to align patient-provider incentives so doctors can make a profit by prioritizing preventive care. Harlan discusses a study suggesting that physical exercise may be protective from severe COVID. Howie highlights the introduction of Apple’s VR headset and the importance of further study to understand the technology’s capacity to “rewire” our brains. Links: "Aledade: Home Page" “Farzad Mostashari: Man On A Digital Mission” “Health Reform and Physician-Led Accountable Care:The Paradox of Primary Care Physician Leadership” “Staggering Rise in Catheter Bills Suggests Medicare Scam” “Accountable Care Organizations (ACOs): General Information” “Novid: Definition” “Prepandemic Physical Activity and Risk of COVID-19 Diagnosis and Hospitalization in Older Adults” “VR risks for kids and teens” “2024 Outlook: Despite hurdles, stakeholders bullish on VR in behavioral health” “AI therapy and ICU training: A first look at health apps for Apple Vision Pro” “Effects of an Immersive Virtual Reality Intervention on Pain and Anxiety Among Pediatric Patients Undergoing Venipuncture” “Virtual Reality for Management of Pain in Hospitalized Patients: Results of a Controlled Trial” “Virtual Reality Reduces Pain in Laboring Women: A Randomized Controlled Trial” “Apple Vision Pro”  Learn more about the MBA for Executives program at Yale SOM. Learn more about the Pozen-Commonwealth Fund Fellowship in Health Equity Leadership. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Christopher O’Connor, CEO of Yale New Haven Health, to discuss his career path and his experience leading hospitals through Hurricane Katrina and COVID-19. Harlan reports on promising AI tools for taking clinical notes; Howie looks at the financial headwinds facing the companies offering Medicare Advantage plans.  Links: AI Notetaking “OpenAI-backed healthcare AI startup raises $70 million Series B” “Burnout Related to Electronic Health Record Use in Primary Care” “Ambient Artificial Intelligence Scribes to Alleviate the Burden of Clinical Documentation” “Medical AI scribe startup Nabla rolling out tool to the Permanente Medical Group docs in Northern California” “Ambience Healthcare reels in $70M for generative AI tools to battle clinician burnout” Hospital Leadership "After 20 Years and $16,000, A Hospital Debt Is Canceled" Harlan Krumholz: “Out‐of‐Pocket Annual Health Expenditures and Financial Toxicity From Healthcare Costs in Patients With Heart Failure in the United States” "Connecticut hospitals face record financial losses" "Update on Effect of Hurricane Katrina on Ochsner Clinic Foundation, LA" "YNHH and Hospital of Saint Raphael become one" Medicare Advantage “Humana slashes profit predictions amid soaring Medicare Advantage costs” HHS: “Biden-Harris Administration is Strengthening Medicare; Protecting and Serving America’s Seniors” "Cano Health’s downfall offers a warning for Medicare Advantage" CMS: Risk Adjustment Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Manisha Juthani, a Yale infectious disease specialist and commissioner of the Connecticut Department of Public Health. They discuss her research, including a study casting doubt on the use of cranberries to prevent urinary tract infection, and her priorities for Connecticut. Harlan reports on a wave of study retractions from the Dana-Farber Cancer Institute; Howie reflects on the progress made toward eradicating Guinea worm and malaria.  Links: Retractions from the Dana-Farber Cancer Institute “Dana-Farber Cancer Institute Researchers Accused of Manipulating Data” “Top Cancer Center Seeks to Retract or Correct Dozens of Studies” Pubpeer: The Online Journal Club “‘A lot of it is sloppiness’: the biologist who finds flaws in scientific papers” Manisha Juthani “An Outbreak of Domestically Acquired Typhoid Fever in Queens, NY” Manisha Juthani: “Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes—A Randomized Clinical Trial” “Reduction of Bacteriuria and Pyuria After Ingestion of Cranberry Juice”  Yale School of Medicine Medical Grand Rounds: “Debunking a myth: cranberry products for UTI prevention” Connecticut Department of Public Health Connecticut Department of Public Health: About the Commissioner Connecticut Department of Public Health: Statistics and Research “Court: CT can keep law that ends religious exemptions for vaccines” “Congenital syphilis cases in the U.S. have skyrocketed, CDC says” Eradicating Parasites “Jimmy Carter took on the awful Guinea worm when no one else would—and he triumphed” “Cape Verde reaches malaria-free milestone” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Yale SOM alum Claudine Litman, a designer and the director of Yale‘s Center for Outcomes Research & Evaluation, to talk about using the tools of design to build more effective healthcare spaces and processes. Harlan looks at seven charts illustrating the state of healthcare in 2023; Howie reports on the FDA reprimanding a drug company for misleading advertising. Links: Healthcare in 2023 "Seven Charts That Sum Up U.S. Healthcare In 2023" Designing Better Healthcare Yale School of Medicine:Center for Outcomes Research & Evaluation Design for Care: Innovating Healthcare Experience This Is Service Design Doing: Applying Service Design Thinking in the Real World The Design of Business: Why Design Thinking is the Next Competitive Advantage Misleading Advertising "FDA scolds Novartis over a misleading TV ad for a breast cancer treatment" Public Law 87-781, 76 STAT 780 FDA: Letter to PharmD Direct-to-Consumer Prescription Drug Advertisements:  Presentation of the Major Statement in a Clear, Conspicuous, and Neutral Manner in Advertisements in Television and Radio Format Final Rule Questions and Answers Guidance for Industry NIH: Direct-to-Consumer Pharmaceutical Advertising Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan are joined by Reshma Ramachandran, a Yale family physician and co-director of Yale Collaboration for Regulatory Rigor, Integrity, and Transparency. They discuss the potential ramifications for healthcare regulation if the Supreme Court overturns the Chevron decision requiring judges to defer to federal agencies. Harlan looks at surveys suggesting an erosion of trust in medicine; Howie reports on the growing measles outbreak. LInks: Trust in Healthcare “Nurses First, Doctors Distant Second in Healthcare Provider Ratings” “KFF Health Tracking Poll: Health Care Issues Emerge as Important Topics on 2024 Campaign Trail, Plus Concerns Loom Large Around Medicaid Unwinding” Reshma Ramachandran “What is Ayurveda?” “On Writ of Certiorari to the United States Court of Appeals for the First Circuit: BRIEF OF DR. RESHMA RAMACHANDRAN AND DR. JOSEPH S. ROSS AS AMICI CURIAE IN SUPPORT OF RESPONDENTS” “Agencies’ Power Under Scrutiny in Supreme Court Arguments” “Supreme Court could reel in power of federal agencies with dual fights over fishing rule” “Case brought to Supreme Court by herring fishermen may gut federal rulemaking power” Reshma Ramachandran: “Medical Product Industry Ties to Patient Advocacy Organizations’ Executive Leadership” Reshma Ramachandran: “Do Advocacy Groups Always Put Patient Interests First?” “Citizens United Explained” The Measles Outbreak “Another person infected with measles at a Northeast daycare as Philadelphia outbreaks grows to nine cases” “DC Cautions Residents of a Potential Measles Exposure” CDC: Measles Cases and Outbreaks Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
Howie and Harlan discuss the winter wave of COVID-19 and Howie’s experience with the Novovax vaccine, report on potential side effects of the next-generation weight-loss drugs, and unpack the economics of Florida’s plan to import drugs from Canada.  Links: Sid Wolfe “Sidney M. Wolfe, Scourge of the Pharmaceutical Industry, Dies at 86” COVID-19 “Florida surgeon general calls for halt on mRNA covid vaccines, citing debunked claim” "Safety and Adverse Events Related to Inactivated COVID-19 Vaccines and Novavax;a Systematic Review" “Paul Offit Debunks Florida Surgeon General's Anti-Vax Warning” “Does Novavax's Covid vaccine cause fewer side effects?” “SOTP: State-of-the-Pandemic: The pandemic's 2nd biggest wave of infections and what the JN.1 variant is telling us” “Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate” Weight-Loss Drugs  “FDA looking into reports of hair loss, suicidal thoughts in people using popular drugs for diabetes and weight loss” “Semaglutide and risk of suicidal ideations” “January - March 2023 | Potential Signals of Serious Risks/New Safety Information Identified by the FDA Adverse Event Reporting System (FAERS)” Elevance and Medicare “Elevance sues HHS over Medicare Advantage star ratings” “How the Tukey Method Could Impact Star Ratings” TriNetX: Explore. Discover. Connect Large Language Models “Diagnostic Accuracy of a Large Language Model in Pediatric Case Studies” “Artificial Intelligence and Machine Learning in Clinical Medicine, 2023” Drug Imports “US FDA to allow Florida to import cheaper drugs from Canada” “FDA approves Florida's request to import cheaper drugs from Canada” “Price-Fixing Case Reveals Vulnerability of Generic Drug Policies” June Jackson Christmas  “June Jackson Christmas, Pioneering Psychiatrist, Dies at 99” Read an unedited transcript of this episode. Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.
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