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Prosthetic Gods
Prosthetic Gods
Author: James Hughes and Nir Eisikovits
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Welcome to “Prosthetic Gods,” the podcast where bioethicist James Hughes and philosopher Nir Eisikovits engage in spirited debates on the ethics and politics of emerging technologies. Hughes, a pro-technology transhumanist, and Eisikovits, with his Luddite stance, explore topics from brain-computer interfaces to artificial intelligence. Tune in and explore the promise and perils of technological advancements with us!
54 Episodes
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Episode 52 - Retired Predator Pilot Reflects on Autonomous Weapons
Our guest this week has done something few philosophers of war can claim: he has flown the aircraft he writes about. We sit down with drone pilot and philosopher Joe Chapa to interrogate the widening gap between technological capability and moral judgment on the modern battlefield. Chapa deconstructs the rush to embed machine learning across military hierarchies, cautioning against blind faith in statistical prediction systems operating under the irreducible fog of war. We examine whether remote combat dilutes the martial virtues or merely reconfigures psychological burden, exploring the acute ethical friction between human tactical restraint and algorithmic certainty. Finally, the conversation confronts the geopolitical reality of autonomous weapons, contrasting commercial software dependencies with the elusive promise of an artificial moral conscience.
Joseph Chapa holds a PhD in philosophy from the University of Oxford and has served as a Predator pilot and instructor of philosophy at the Air Force Academy, logging more than 1,400 pilot and instructor pilot hours. His work centers on just war theory, military ethics, and especially the ethics of remote and autonomous weapons.
He also knows the Pentagon from the inside. He previously served as the Department of the Air Force’s first Chief Responsible AI Ethics Officer and has taught as a military faculty member at the Marine Command and Staff College. He retired from the Air Force October 1st. He is the author of Is Remote Warfare Moral? (PublicAffairs, 2022), which examines remote warfare within the context of the just war tradition, virtue, moral psychology, and moral responsibility, and, more recently, AI for the Rest of Us (Air University Press, 2026). He writes the weekly newsletter Views Expressed, and we’re delighted to welcome him as our new postdoctoral colleague. Joe, welcome to the show.
Show Notes:
Joseph Chapa’s website
Is Remote Warfare Moral? Weighing Issues of Life and Death from 7,000 Miles by Joseph O. Chapa
AI for the Rest of Us: Understanding the Technology That’s Shaping Our World by Joseph O. Chapa (Air University Press)
Views Expressed (Joe Chapa's Substack newsletter)
Masters of the Air: America's Bomber Boys Who Fought the Air War Against Nazi Germany by Donald L. Miller
Supergirl: Woman of Tomorrow (Discussed in relation to revenge, martial virtue, and moral injury)
As always, listeners can contact us at [email protected] with questions, comments, and suggestions for future topics.
Credits:
Hosted by James Hughes and Nir Eisikovits
Music & Production by Jake Burley
Episode 51 - Uploading Yourself to the Cloud
This week on Prosthetic Gods, Nir and J discuss the transhumanist concept of brain uploading, exploring everything from cutting-edge connectomics and artificial intelligence to ancient philosophical views on personal identity. We debate the metaphysics of “substrate independence,” “computational functionalism,” and religious views of the soul to weigh the prospects of preserving consciousness. They also examine the practical and ethical implications of creating digital simulacra, including duplication problems, machine suffering, and moral responsibility.
Show Notes:
Connectome 2.0 Project: A National Institutes of Health (NIH) initiative utilizing an advanced MRI scanner to map brain connections down to a single micron level.
Eon Systems Fly Cyborg: A simulated fruit fly connectome connected to a virtual body to simulate behaviors like walking and grooming.
Carboncopies Foundation - research and development toward whole brain emulation.
Blue Brain Project - a Swiss project to model the brain that concluded work in 2024.
Virtually Human: The Promise and the Peril of Digital Immortality by Martine Rothblatt
State of Brain Emulation 2025: A comprehensive report featuring contributions from 45 authors and the Allen Institute that outlines the roadmap for animal and human brain emulations.
“The Soul of Trans-humanism” by Ted Peters, reflecting on the various interpretations of the soul in Christianity, and their compatibility with uploading
San Junipero - Black Mirror episode on uploading
Duncan Bell on transhumanism on David Runciman’s Past, Present and Future podcast
As always, listeners can contact us at [email protected] with questions, comments, and suggestions for future topics.
Credits:
Hosted by James Hughes and Nir Eisikovits
Music & Production by Jake Burley
Episode 50 - Animal Testing
This week on Prosthetic Gods, Nir and J. dissect the rapid dismantling of the animal-testing paradigm. We explore the legal and political shifts sweeping the EU and the United States—including the surprising federal momentum under the current HHS framework. From the utilitarian calculus of sentient consciousness down to the moral weight of insect neurology, we interrogate whether high-tech alternatives like organoids and AI models can and should finally render mammalian sacrifice obsolete.
Show Notes:
“The global push to reduce animal testing in drug development” Drug Target Review
“HHS Accelerates Shift to Human-Based Research, Reduces Reliance on Animal Testing” US Department of Health and Human Services
“The FDA Finalizes Rule Recognizing Non-Animal Testing Methods, Building on Year-Long Reduction Push” PharmTech
“The future of science without animal testing” Humane World for Animals
“A Kantian Case for Animal Rights” Christine Korsgaard
Animal Liberation Now: The Definitive Classic Renewed Peter Singer and Yuval Noah Harari
Lanterns on HBO
Piers Morgan interview with AI actress derailed by Cantonese
As always, listeners can contact us at [email protected] with questions, comments, and suggestions for future topics.
Credits:
Hosted by James Hughes and Nir Eisikovits
Music & Production by Jake Burley
Episode 49 - Targeting at Machine Speed
This week on Prosthetic Gods, Nir and J speak with Major Michael Brodka, a U.S. Army military intelligence officer and author of the July 2026 Military Review article “By Algorithm or Order.” Major Brodka argues that the U.S. Army's human-paced targeting doctrine is dangerously misaligned with the rapid emergence of machine-speed, AI-enabled warfare being pursued by adversaries like China and Russia. It asserts that to close this critical "velocity gap," the military must reform its doctrines, organizations, and training to integrate lethal autonomous weapon systems under lawful human-on-the-loop control.
Show Notes:
“By Algorithm or Order” Michael Brodka
DoD Directive 3000.09: Autonomy in Weapon Systems
Department of Defense Law of War Manual
Field Manual (FM) 3-60:Army Targeting
2023 DoD Data, Analytics, and Artificial Intelligence Adoption Strategy
Michael A. Santoro, “Designing Lethal Decisions: AI, Accountability, and the Future of Military Judgment,” Modern War Institute (16 Apr 2026)
Jesse R. Crifasi, “Targeting at Machine Speed: The Capabilities—and Limits—of Artificial Intelligence,” Modern War Institute (17 Jul 2025)
As always, listeners can contact us at [email protected] with questions, comments, and suggestions for future topics.
Credits:
Hosted by James Hughes and Nir Eisikovits
Music & Production by Jake Burley
Episode 48 - Black Mirror
Nir and J discuss the show Black Mirror, the now archetypal tech dystopian cultural phenomenon. In almost every episode, technology is the villain. What rarely appears is a legislature, a regulator, or anyone organizing with anybody else. Technology simply arrives, and the only available moral is individual failure. Dystopian narratives are popular, but what work do they do? Do they spur us to action or disempower us? What would a tech realist version look like?
Show Notes:
Be Right Back - s2e1 - What if we could record and replay every experience?
Metalhead- s4e5 - What if Terminator apocalypse with robot dogs?
San Junipero - s3e4 - What if we could upload our minds to virtual heaven?
Common People - s7e1 - What if capitalism enshittified brain-computer interfaces?
Years and Years
As always, listeners can contact us at [email protected] with questions, comments, and suggestions for future topics.
Credits:
Hosted by James Hughes and Nir Eisikovits
Music & Production by Jake Burley



