Talking Transfusion: The Transfusion Evidence Round-Up Podcast

Postpartum haemorrhage is the leading cause of maternal death globally. This year’s theme for World Postpartum Haemorrhage Day is “Translating evidence into action” — a theme that highlights the importance of turning research and recommendations into real-world practice.In this episode, our reviewers explore selected publications from the World Health Organization (WHO), the International Federation of Gynecology and Obstetrics (FIGO), and the International Confederation of Midwives (ICM). We look at the evidence on postpartum haemorrhage and, most importantly, discuss how we can translate that evidence into action to improve care and outcomes for women worldwide.

Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviewsIn this episode, Lise Estcourt talks to Catherine Kimber about her recently updated overview of Cochrane systematic reviews, looking at red cell transfusion interventions in sickle cell disease.  She talks about what the new overview tells us and highlights important evidence gaps that still exist in this area.

What is an overview of systematic reviews?In this episode, Lise Estcourt talks to Susan Brunskill about the process of conducting an overview of systematic reviews.  They discuss why overviews are useful, what kinds of questions can be answered with an overview, how the work is done and when to update them.

In honour of International Thalassaemia Day, in this podcast episode, we explore top research relating to transfusion and stem cell transplantation in people with thalassaemia. Our reviewers cover a range of topics including novel oral treatments, different preparations of red blood cell products and allogeneic haematopoietic stem cell transplantation.

Welcome to this special quarterly edition of the Transfusion Evidence Round-Up, produced by the International Society of Blood Transfusion (ISBT) and the Transfusion Evidence Library (TEL). In honor of International Childhood Cancer Day, we’ve partnered with the ISBT Cellular Therapies Working Group to bring you a joint Round-Up highlighting the latest evidence in both Transfusion Medicine and Cell Therapy.In this episode, we explore top research shaping pediatric hematology and stem cell transplantation, including the impact of minimal residual disease on outcomes in childhood acute lymphoblastic leukemia from the FORUM Trial. We also highlight advances in TCRαβ/CD19-depleted hematopoietic stem cell transplantation, second transplants for relapsed acute myeloid leukemia, and outcomes following CAR-T therapy in children and young adults.Whether you’re a transfusion specialist, cell therapy researcher, or healthcare professional interested in pediatric oncology, this top-ten selection of articles offers insights that cross the boundaries of both fields.