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Proof of DeSci

Author: ValleyDAO

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Proof of DeSci by ValleyDAO is a podcast series showcasing real scientific breakthroughs funded through decentralized science. Each episode dives into research milestones, researcher stories, and the impact DeSci is creating, proving that decentralized science works.

10 Episodes
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In this episode of Proof of DeSci, we’re joined by Daniel (Head of Competition) and Tim (Co-founder of First Approval) to talk about the Student Biological Data Competition 2025, a global initiative empowering students to publish and share biological datasets, practice reproducible science, and gain visibility early in their careers. We explore the big picture of open science: why reproducibility, transparency, and data sharing are crucial for scientific progress, and how changing the mindset...
In this episode of Proof of DeSci, we sit down with Jake Wintermute, synthetic biologist, science communicator, and former developer evangelist at Ginkgo Bioworks, to explore the future of decentralized science. Together with Albert and Morgan from ValleyDAO, we dive into the big themes shaping DeSci today: how lab automation and cloud labs could transform decentralized research, the role of DIY bio and iGEM as models for distributed science, and why culture, cost, and education are jus...
In this episode of Proof of DeSci, we’re joined by Erik from Bio.xyz to unpack one of the most anticipated updates in the DeSci space, BIO V2. We dive into how V2 changes access, participation, and opportunities for builders and backers, and what this means for the future of decentralized biotech funding. Alongside Erik, we explore the pulse of DeSci Summer, the signals showing real market traction, and how community-driven models are shifting the balance away from purely speculative funding....
In this episode of Proof of DeSci, we sit down with Caroline and Eshwar, winners of the Phlo Hackathon, to talk about their project Pearlfect Millet, a synthetic biology idea aiming to optimize millet for better taste and resilience. We dive into their scientific backgrounds, what drew them into DeSci, and how they leveraged Phlo’s research agents to go from idea to execution in just a few days. They share their experience using Phlo for literature review, business strategy, and validating co...
In this episode of Proof of DeSci, we explore the power of community and creators in shaping the future of decentralized science. Joined by That Investor, Andrew Hemingway, Morgan and Albert from ValleyDAO, we dive into how DeSci communities are flipping the script on traditional science funding, why content creators and influencers are becoming vital to the movement, and how crypto-native culture is accelerating interest in climate biotech. From the speed of funding to the value of sto...
In this episode of Proof of DeSci, we’re joined by Michael Luciani, co-founder of Juniper VC, a climate biotech-focused venture firm backing the next wave of synthetic biology and sustainable innovation. We dig into: How Juniper VC sees biotech beyond pharma, investing in food, materials, and planetary healthThe real opportunities in climate biotech, from biomining to engineered agricultureWhy Juniper is betting on DeSci and what led them to invest in ValleyDAOHow AI, declining biomanufacturi...
In this exciting episode of Proof of DeSci, we’re joined by Dr. Rodrigo Ledesma-Amaro and Dr. Oliver Konzock from Imperial College London to dive deep into the Cocoa Zero project, an innovative effort to produce sustainable cocoa fats using synthetic biology. Led by ValleyDAO’s support, this project is a game-changer in the chocolate industry, offering a solution to the rising cocoa prices driven by climate change and supply chain disruptions. Rodrigo and Oliver share their journey behind eng...
In this episode, we’re joined by David Sun Kong, Director of the Community Biotechnology Initiative at MIT Media Labs, to dive deep into the world of decentralized science (DeSci). David shares insights into the innovative “How to Grow Almost Anything” program, a course that empowers students to explore synthetic biology and biotech at scale. We also explore the exciting intersection of DeSci and AI, with a special focus on the potential of Bio Protocol’s AI agents. Additionally, Albert and D...
In this episode, we ask the big question: Is DeSci dead, or just getting started? We’re joined by Geoff Anders from Quantum Biology DAO and Erik Van Winkle from Bio Protocol for a deep dive into the cutting edge of decentralized science. From building quantum microscopes to launching autonomous AI research agents, our guests explore what it means to do science in Web3, and what’s next for the DeSci movement. Hosted by Tom Fraczak (ValleyDAO), with Morgan Richards joining from the ValleyDAO te...
In this inaugural episode of Proof of DeSci, we dive into Hempy’s groundbreaking research, transforming hemp fibers into softer, more sustainable textiles using enzyme treatments. Join Filippo Fabbri (Hempy Project), Ella McCarthy-Page (Molecule), and Albert Anis and Morgan Richards (ValleyDAO) as they discuss the science behind this achievement, the journey of crowdfunding biotech research through decentralized science (DeSci), and why tangible research breakthroughs like Hempy’s prove the D...
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