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A Question of Science

Author: The Francis Crick Institute

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Science you can trust. Questions that matter.  


Join Professor Brian Cox and a panel of the world’s top scientists and experts as they tackle your questions about some of the biggest science challenges facing society today. 


Can we cure cancer? How do you separate nutrition fact from fiction? What do climate change and the march of AI mean for our future? Could we live forever? Each episode is recorded in front of a live audience and it’s their questions that drive the debate. 


Hear from the experts who actually know what they’re talking about, including Adam Rutherford, Helen Sharman, George Monbiot, Giles Yeo, Jeanette Winterson, Rory Cellan-Jones, Paul Nurse, Kevin Fong and You, Me and the Big C’s Lauren Mahon.  


With a focus on accuracy, openness, and debate, A Question of Science brings you the latest on what we know, what we don’t, and where science might take us next. 


A BBC Studios production for the Francis Crick Institute, an independent charity and world-leading research lab. 

25 Episodes
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How important is our gut microbiome and could it hold the key to new treatments for a range of different diseases? How does the gut-brain axis influence our behaviour and will poo transplants become a regular procedure on the NHS? Join our panel of experts as they discuss the secrets of our ‘second brain’ – the gut. From major advances in research to the difference between prebiotics andprobiotics. Panel: Prof Glenn Gibson: Emeritus Professor of Food Microbiology at the University of Reading Prof Lindsay Hall: Chair of Microbiome Research at the University of Birmingham’s Institute of Microbiology and Infection Prof Jatin Nagpal: Researcher at University College Cork’s APC Microbiome Ireland Centre Prof Sheena Cruickshank: Immunologist and Professor in Public Engagement and Biomedical Sciences at the University of ManchesterSee omnystudio.com/listener for privacy information.
Our biological sex affects every cell in our body, so how does it influence our health - from embryo development through to the risk of disease and diagnosis? How and why do some conditions affect females and males differently? And what can we do to ensure medicine is safe and effective for everyone, after decades of male biology bias? Across autoimmune disorders, cancer, dementia, heart disease and even responses to everyday medications, sex‑based biological differences can shape who becomes ill, how symptoms appear and what treatments work. Join our expert panel as they explore sex differences in biology, hormones and gene regulation. Panel: Prof Edith Heard, CEO of the Francis Crick Institute  Natasha Karp, Biostatistician at Astra Zeneca  Prof Petter Brodin, Garfield Weston chair of Neonatology and Professor of Paediatric Immunology, Imperial College, London Caroline Criado Perez, Author of Invisible Women  See omnystudio.com/listener for privacy information.
Can we cure addiction?

Can we cure addiction?

2026-10-1442:411

Why do people become addicted? When does a habit turn into self harm and what makes recovery so hard? From drugs and alcohol to gambling and social media, join our panel of experts as they explore the causes of addiction, what it looks like in the brain and potential new treatments, including psychedelic therapies. Panel: Prof Sally Marlow: Professor of Public Understanding of Mental Health at KCL  Matt Willis: Musician/actor and podcaster in recovery from addictions   Dr Nicky Kalk: Psychiatrist and addiction specialist at Maudsley NHS Trust  Prof David Nutt: Director of the Neuropsychopharmacology Unit, Imperial College, LondonSee omnystudio.com/listener for privacy information.
How is AI revolutionising medicine and drug discovery and could it really improve diagnosis and treatment for everyone?  Could the role of doctors and nurses change forever, with AI taking care of admin and analysis at the touch of a button?  Can we trust it to safeguard our health and our personal data – and who gets to control it?  Join a panel of experts as they answer your questions and explore how AI is rapidly changing medicine and healthcare, now and in the future. Panel: Prof Mihaela van der Schaar: Chief AI Scientist, The Francis Crick Institute Dr Indra Joshi: Chief Product Officer, Optum UK Lord Patrick Vallance: Former Minister of State for Science Prof Samra Turajlic: Group Leader, Cancer Dynamics Laboratory, The Francis Crick Institute and Director, Cancer Research UK Manchester Institute  See omnystudio.com/listener for privacy information.
A Question of Science is back - with free tickets to live recordings available now! Join Professor Brian Cox in person and put your questions to a panel of leading scientists and experts on a huge range of topics. We’ll be exploring how A.I. is changing medicine, what’s really happening inside the teenage brain, how can science help save our oceans, beat superbugs, tackle addiction, and what elite sport science can teach us about human strength and endurance.  The series is being recorded in June and July at the Francis Crick Institute in London, one of the world’s leading centres for biomedical research. To book your tickets visit: crick.ac.uk/tickets  See omnystudio.com/listener for privacy information.
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