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The Longevity Loop Podcast
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The Longevity Loop Podcast

Author: Brent Wallace

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The Longevity Loop with Brent Wallace is for dads who want to still be playing with their kids, and their grandkids, in their 80s and 90s.
Not the guy with a $50,000 budget and a full-time coach. The guy with a job, a family, and 45 minutes a day.
Brent's been running experiments on himself since 2018. Nutrition degree, 20-plus biomarkers tracked, too many supplements on the counter, and a kid who does not slow down. He's spent real money finding out what works and what's a waste, and he'll tell you which is which.
Every week he talks with docs, scientists, founders, and coaches, and asks what you'd ask. Does this actually work? What does it cost? What would you do if it were your own body?
We call out the hype, skip the noise, and get to what actually works in the real world.
This is education, not medical advice, so talk to your own doc before you change anything.
Watch the video version: youtube.com/@TheLongevityLoop
Brent runs Spannr.com, a vetted directory of longevity clinics and practitioners, and founded LongevityClinicMarketing.com. 

31 Episodes
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Dr. Michael J. Hall: What Actually Earns a Spot in Your Protocol Episode Summary Brent Wallace speaks with Miami Beach longevity physician Dr. Michael J. Hall, author of *Infinite Youth: Solving the Aging Equation*, about what deserves a place in a longevity protocol. They examine supplement hype, rapamycin, methylene blue, growth hormone, resveratrol, and why sleep, nutrition, and movement come first. What You'll Hear - How Dr. Hall weighs clinical evidence and before-and-after labs over...
Sanjiv Lal spent twenty years building pharmaceutical, diagnostic, and laboratory companies. Then at forty, he became the patient, and the system he helped build told him to manage his decline. In this episode, Brent talks with Sanjiv about what happened next, and about the peptide boom nobody is explaining honestly. They get into what peptides actually are, why the FDA is reconsidering its restrictions on roughly nineteen of them, and what's really inside the vials people buy online. You'll...
Episode summary Dr. Quinto Pauletti joins Brent Wallace to discuss a challenge he sees in high-performing executives: some have neglected their health for years, while others have accumulated mountains of health data without knowing what it means. His approach starts with the fundamentals, then looks for missing pieces through health history, testing, wearables, lifestyle, oral health, and other tools. For people in their 40s and 50s trying to optimize everything at once, the takeaway is simp...
We talk with Dr Ron Primas about what actually improves healthspan when you strip away expensive hype and focus on the basics that work. We dig into prevention, training, testing, and the social support that helps people stay resilient as they age. • Lessons from caring for ultra-wealthy patients, including why money does not replace sleep, exercise, nutrition, and fasting • Why social support and built-in care teams can extend functional years in extreme old age • The Manha...
You can buy a “longevity stack” in 30 seconds, but you can’t buy your way around biology. Today we sit down with Sergei Yakimov, a longevity-focused VC who has reviewed thousands of companies and only funded a handful, to unpack what actually earns conviction when real money and real outcomes are on the line. We dig into the difference between evidence-based biotech and consumer longevity hype: why clinics, stem cell storefronts, peptide trends, and easy app plays often fail the defensibilit...
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