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The Long Game

Author: Sandy & Ross

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The Long Game is a podcast that demystifies the science shaping our lives, and explores how great ideas built in Scotland become real-world medicines, devices, and companies at the cutting edge of life sciences.

27 Episodes
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Private full-body MRIs are booming - but are you buying peace of mind or simply new things to worry about? Healthy people are lining up for scans that promise certainty, early detection, and control. Sandy Weir and Ross Cagan reveal why that promise can backfire, turning reassurance into anxiety, follow-up tests, and overdiagnosis. This episode unpacks the private scan boom and the uncomfortable truth behind elective whole-body MRI. Ross and Sandy explain why scanning a healthy body is not the same as investigating symptoms, and why the difference matters more than most marketing ever admits. When a scan finds a tiny cyst, nodule, or shadow, the question is not just "what is it?", it is "can you unsee it?"
Most longevity clinics are selling a seductive story, not proven results. If you care about biological age tests, rapamycin, supplements, or the booming market for “optimization,” this episode separates the real science from the expensive theatre. Ross Cagan and Sandy Weir take on the new body economy and ask the question at the centre of the longevity clinic boom: what actually improves health span, and what is just measurement, hope, and status wrapped in a premium price tag? The answer is more nuanced than the hype suggests, and far less magical than the marketing.
The Ozempic economy is already reshaping what people eat, how companies sell, and which health systems can afford to keep up. Sandy Weir and Ross Kagan kick off The Body Economy, a six-part series that starts with the drugs behind the headlines and ends with a much bigger question: what happens when appetite itself becomes medically adjustable?
One contaminated lab plate helped launch a multi-billion-dollar industry, save hundreds of millions of lives, and trigger one of the biggest IP blunders in British history. Ross Cagan and Sandy Weir trace the penicillin story from Alexander Fleming's messy "failed" experiment to the commercialisation race that changed medicine forever. They unpack how Fleming spotted the blue-green mould that killed staph bacteria, why his breakthrough sat ignored for a decade, and how Howard Florey and Ernest Chain turned the discovery into a scalable manufacturing process during World War Two. Along the way, they reveal why the real breakthrough wasn't just scientific, it was industrial, legal, and deeply political.
A doctor tried to erase two murders so completely that he turned the crime scene into a puzzle.What finally exposed the truth was not a confession, but forensic ingenuity; skull reconstruction, photographic superimposition, and insects that could timestamp death with uncanny precision.Ross Cagan and Sandy Weir unpack the infamous Buck Ruxton case, known as the Jigsaw Murders and Bodies Under the Bridge, and show how a 1935 killing in Moffat helped redefine modern forensic science.
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