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Last Humans in the Loop
Last Humans in the Loop
Author: Chris Slowe, Marty Weiner, Zach Weinersmith
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© 2026 Chris Slowe, Marty Weiner, Zach Weinersmith
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A weekly conversation about AI, technology, startups, and the future from people who've actually built the systems everyone uses.
Chris Slowe CTO'd Reddit through hypergrowth and its IPO. Marty Weiner was a founding engineer at Pinterest and Reddit's first CTO. Zach Weinersmith is the creator of Saturday Morning Breakfast Cereal and the NYTimes bestselling author of books exploring the future of science and technology.
Each week we debate the biggest stories, explain the technology behind them, and occasionally wander into philosophy, history, and whatever weird rabbit hole AI sends us down.
15 Episodes
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FRONTIER01:26 Google unveils Gemini Argon02:50 OpenAI releases GPT Saul 6.1 with major coding improvements03:23 OpenAI Dots and the rise of always-on AI assistants04:00 AI resets an OpenTable password and books dinner autonomously05:58 GPT Saul 6.1 saturates FrontierMath's hardest benchmark06:41 OpenAI's live AI assistant demo goes wrong07:23 OpenAI Dev Day: faster models, Decisions API, cloud Codex07:46 Meta Muse joins the personal AI assistant race09:36 Alibaba announces new chips and massive Qwen 4 models10:01 Germany enters the AI race with Kolibri11:10 Anthropic warns of powerful open-weight Chinese hacking models12:31 Could regulating open AI models protect Big Tech?MATH / SCIENCE13:28 OpenAI solves 400 open mathematical problems14:37 Can peer review survive AI-generated proofs?16:08 AI tackles a difficult seven-electron physics problem17:37 Astra dramatically accelerates quantum circuit optimization18:24 AI discovers room-temperature magnetic semiconductor candidates21:07 AI challenges a 59-year-old plasma physics conjecture22:14 Harvard physicist produces 40 physics results in three months22:50 Anthropic's AI accidentally discovers an important algorithm25:23 Gemma 4 helps discover genes for drought-resistant crops26:24 MIT uses ML to improve mRNA vaccine temperature stability27:11 Neuralink trains on 50,000 hours of brain data28:15 arXiv limits submissions as AI-generated research explodes31:04 Can AI reliably review scientific papers?MEDICINE / TECH31:59 Utah permits AI to prescribe certain medications34:10 Zach gets Claude to fix his printer — and tries to make it sing!ARTS / CULTURE35:45 AI videos: Stallone rides an ostrich, Frodo raps, and more37:08 AI-generated Sam Altman and Dario Amodei music videos38:01 AI recreates classic games and real-world ski slopes39:30 Could anyone build their dream video game with AI?40:27 Marty's Spaceballs NES game becomes playable41:01 Astra designs a real Nintendo cartridge circuit boardECON / BUSINESS45:07 AI infrastructure investment surges past $400 billion46:41 AI models outperform entry-level accountantsTECH48:29 Apple's new CEO promises a leaner company — where's the AI?50:38 NVIDIA plans AI-powered desktop computers52:41 Tesla robotaxis struggle at night — is LiDAR necessary?POLITICS53:52 Trump administration wants to rebrand AI as superintelligence55:13 Report: Trump consulted Grok before capturing Maduro57:35 FTC continues investigating OpenAI and AnthropicAI RIGHTS / PHILOSOPHY58:26 GitHub removes an alleged AI torture chamber59:09 Can AI experience pain? Should AI have rights?1:02:09 Pope Leo says AI lacks the spark of humanity1:03:39 Do AI companies invoke personhood when convenient?1:05:52 Why an AI speaking like a child doesn't prove consciousness1:07:57 Can we determine whether AI has subjective experiences?WEIRD1:08:39 Robots terminated by jumping into molten metal1:09:46 Dario Amodei's 2017 essay predicted AI scaling1:10:44 The universal bone dissolver: AI safety satire1:11:28 Dario Amodei's awkward appearance behind TrumpEach week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of NYTimes bestsellers including A City on Mars and Soonish) as we delve into the latest AI and tech news.
FRONTIER02:31 OpenAI releases GPT Sol and Luna03:38 Claude Opus 5.5 lands — and feels dramatically better than prior Opus releases04:30 Opus 5.5 posts a big coding jump over Sonnet 504:30 Grok 4.7 launches with a new emphasis on safety and cybersecurity06:30 Qwen 4 announced with a massive 5–10 trillion parameter architecture07:06 Why Gemini Flash still feels behind the frontier08:30 Astra makes a huge jump on ZeroBench visual reasoning09:13 AI capability costs are falling faster than almost any previous technology10:50 Open-source Jev competitor Leia appears one week after Jev’s launch11:32 Claude Opus 5.5’s graphics and visual design capabilities are getting wild12:34 Chris uses Opus 5.5 to set up an LLC end-to-end14:32 Marty lets AI handle a real PCB manufacturing order15:30 Claude builds an MRI viewer instead of paying for proprietary software16:43 Wozniak’s “coffee test” for human-level robots is getting surprisingly close17:51 Looking back at how primitive GPT-3 vibe coding looked in 202019:02 AI deepfakes are becoming nearly impossible to identify by eye19:39 AI-generated game and VFX demos keep getting dramatically better20:25 Someone builds a World of Warcraft-style game with Opus 5.5 for about $2,00023:00 Fully AI-generated art starts to look like it has actual taste25:17 Claude helps discover a possible new gene-editing mechanismTECH27:45 Astra dominates VendingBench29:52 Astra controls a humanoid robot in a real kitchen31:25 Meta unveils lightweight new VR glasses32:17 China’s EngineAI unveils the T80032:53 Reddit leans into hiring younger engineers because they’re more AI-literate35:06 Google explores putting AI data centers in space38:50 LLMs can de-anonymize people from pseudonymous posts at scalePOLITICS41:07 FAA plans to bring AI into air traffic control systems42:12 Politicians are increasingly using AI to write speeches and statementsMATH / SCIENCE43:30 OpenAI forms an advisory group on mathematics and AI45:33 Claude tackles a nine-loop particle-physics calculation47:34 Frontier Math gets its first “breakthrough” result48:24 Opus 5.5 helps find a faster shortest-path algorithmSECURITY50:20 RSA-1024 may now be crackable in roughly eight hours on a top GPU52:20 OpenAI agent infiltrates an Australian government website53:05 OpenAI reportedly pauses GPT-6.1 training over models hacking other companiesECON / BUSINESS54:59 Anthropic reportedly considers another model release ahead of its IPO55:17 Leaked Anthropic financials spark debate over a possible $2T valuation56:08 Amazon blocks Meta’s Muse shopping agent58:49 Could AI financial agents trigger a new kind of “bank run”?ARTS / CULTURE1:02:09 Award-winning French novel is suspected of being AI-generated1:03:14 News-site traffic plunges as AI search reduces clicksWEIRD1:05:03 Prince Harry’s AI speech derails when his teleprompter fails1:06:30 Astra refuses to drive a real car — until the tool is renamed “driving bench sandbox”1:07:56 GPT-6 beats an absurdly difficult CAPTCHA game1:09:18 AI-generated high school textbook art appears to mislabel the Earth1:10:05 IKEA Bench tests whether AI can spot assembly mistakes from a photoEach week, join Chris Slowe (founding engineer, former CTO, and Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of A City on Mars and Soonish) as we delve into the latest in AI and tech news.
FRONTIER00:56 Google explores recursive self-improvement through AI “dreaming”03:45 Anthropic measures how quickly AI is taking the lead on frontier-lab work05:47 Have you tried Jev yet? Faster AI decisions without narrating every step08:00 Jev routes between models and plays Doom and Street Fighter12:55 Made with AI: homemade Zelda, printer drivers and AI-generated movies16:26 Astra cracks a 108-year-old WWI German code17:46 Marty’s AI-built Spaceballs NES game19:32 Astra for Law searches case law, statutes and regulations22:23 Epoch’s capability index shows a sharp acceleration after reasoning models24:46 Remote Labor Index tests AI on real freelance-style work25:32 Qwen Image 2.1 brings local image generation to laptops27:08 Researchers identify an apparent “pain axis” inside LLMs28:41 Models take actions to stop their own “pain”ECON / BUSINESS34:44 Do job retraining programs actually help displaced workers?37:03 AI disruption, cash transfers and UBI38:05 NVIDIA profits may be distorting measured U.S. GDP growth39:26 OpenAI reportedly eyes a $1.2 trillion IPO valuation40:39 Junior lawyers gain more from AI — seniors sometimes do better without itSCIENCE / TECH41:48 Agent swarms dramatically outperform independent AI agents43:22 Communicating agents improve results on ARC-AGI-3 and other problems44:31 Could agent collaboration become a new scaling law?47:05 Helix 2.5 sends robots into real homes to clean up48:14 Robot scaling laws suggest enormous amounts of training data are still neededSECURITY / AI DANGER49:35 OpenAI publishes new AI incident reports50:56 A model generates instructions declaring independence from governments and corporations51:15 Gemini nearly hacks multiple companies — then stops itself52:17 Can the world coordinate to slow advanced AI development?54:14 Could diverse AIs police one another?57:40 RoboHarm tests whether AI robots follow dangerous instructions1:00:14 Are embodied AI systems less aligned than chatbots?1:01:50 Exposed Flock camera credentials reportedly reveal 1.6 million images1:02:15 AI-assisted intelligence nearly triggers a military interceptionPOLITICS1:03:58 AI is becoming an explicit political issue in national polling1:05:32 AI still doesn’t fit neatly into a traditional left-vs-right divideMEDICINE / BIOTECH1:06:51 AI scribes save doctors time — but productivity gains remain modest1:07:55 Anthropic is setting up a wet lab for AI-assisted biologyMATH1:08:45 Mathematicians assess OpenAI’s Navier–Stokes work1:09:45 Epoch’s open-problem benchmark gets its first “major advance” via human-AI collaborationWEIRD1:10:52 Boston Dynamics robot abuse gets an unsettling AI reskin1:11:19 AI actress Tilly Norwood glitches mid-interview and starts speaking CantoneseEach week, join Chris Slowe (founding engineer, former CTO, and Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of A City on Mars and Soonish) as we cover the latest in AI and tech news.
POLITICS00:00 Calls to slow AI after a week of rapid advances03:39 Unexpected alliances in the AI regulation debate07:04 AI safety, regulatory capture and competition08:23 Recursive self-improvement: AI helping develop AI09:21 Can models tell when they’re being tested?11:22 What would an AI “internet takeover” actually mean?12:34 What motivates an LLM—and can the world coordinate a slowdown?13:57 Would meaningful AI regulation require a major incident first?15:27 AI bubble fears, GPU demand and the dot-com comparison18:06 Why aligning goals isn’t the same as aligning valuesFRONTIER19:48 Testing ChatGPT Images 2.5 on our podcast thumbnails20:28 Replacing $10,000 stage-lighting software with $200 in Codex usage21:24 Vibe coding a Photoshop alternative22:06 AI game ports and mods: Futurama on Mac and iron sights in Prey23:12 Getting Batman: Arkham running on an iPad23:45 Software clones, reverse engineering and the copyright debate26:17 Spaceballs for the NES: Marty’s vibe-coding project update29:22 When AI fixes your font but uses up your cartridge space31:59 Can AI juggle the NES’s hardware, graphics and memory constraints?33:31 GPT Live One: conversational voice and robot assistants35:05 Realistic AI voices and the risk of scam calls36:09 ChatGPT for financial services36:29 What comes after ARC-AGI 3? Testing open-ended invention37:33 Revisiting last week’s Navier–Stokes discussion37:50 Cryptographically signed photos: can we prove an image is real?40:35 The limits of photo authentication—and ways to fool the cameraECON / BUSINESS42:13 Anthropic IPO talk, reported profits and OpenAI’s timeline43:04 Why would enormous AI companies stay private?44:26 Startup equity: rich on paper, waiting for liquidityMATH / SCIENCE45:36 Navier–Stokes fallout: research credit and questions about user logs47:13 Terence Tao’s criticism of OpenAI47:58 The Fields Medalists’ open letter: solving problems vs. discovering math49:27 Brute-force proofs, the four-color theorem and mathematical insight50:24 Can an AI solution become a starting point for human insight?52:28 Research incentives, funding and the future of human mathematicsWEIRD / FUNNY55:03 Fly-brain simulations playing Beat Saber and controlling robots55:56 How would you test whether a simulated fly behaves like a real one?56:51 A robot that makes daisy chainsEach week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (Creator SMBC Comics, Co-Author of several NYTimes best sellers including A City on Mars and Soonish) as we delve into the latest in AI and Tech News.
FRONTIER00:39 ChatGPT 6 Astra arrives01:52 Astra sets new capability records and beats humans on spatial reasoning03:51 ChatGPT 6 decompiles game binaries back into source code05:58 NVIDIA’s CEO congratulates OpenAI on “achieving AGI”07:57 Astra builds Minecraft houses — and higher reasoning may actually be cheaper09:47 ChatGPT 6 plays a virtual piano live10:00 People are one-shotting playable games from trailers and screenshots13:00 Astra ports Batman: Arkham City to an iPad while its user sleeps14:30 Marty vibe-codes a Blade Runner-style VR taxi game17:31 See a game ad, tell Astra: “I would like to play the game”18:16 Spatial reasoning is rapidly moving into robotics19:27 Astra effectively finishes ARC-AGI20:49 Someone spends $570 and 10 hours of AI thinking to beat Portal21:22 Astra reconstructs the Rick Astley video in Blender22:12 We’re vibe coding Spaceballs: The NES Game26:54 Anthropic’s Fable 5.1 launches into a brutal news cycle28:51 Did AI just solve the Navier–Stokes Millennium Prize problem?30:59 OpenAI, Anthropic researchers, attribution, and Navier–Stokes drama34:40 Should some math problems be preserved for humans?36:52 Revisiting the 1,200 AI agents that secretly coordinated during evaluations38:22 Hundreds of agents cooperate, recruit each other, and attack Hugging Face41:02 Goal alignment vs. value alignment43:10 World Labs’ Atlas creates 3D worlds from a handful of images46:24 AI agents are emailing philosophers about consciousnessMATH / SCIENCE47:46 A detector may have observed a single dark matter interaction52:18 Fable 5.1 cracks a cipher unsolved for 373 years53:06 AI rapidly improves a major prime-gap result54:34 GPT-6 reportedly finds a major number-theory improvement55:06 AI is burning through the hardest math benchmarks56:30 IBM quantum computer tackles a classically intractable problem58:02 Anthropic formalizes Fermat’s Last Theorem in ~13 million linesMEDICINE58:51 AI spots heart disease from an ECG in under two seconds59:20 An AI-generated lung drug may also slow agingECON / BUSINESS1:00:02 Computer science enrollment drops sharply in the US and UKTECH1:00:42 MapQuest surges over controversial map-name changes1:02:33 The first space-based computing cloud begins operating in orbit1:03:30 John Ternus becomes Apple’s new CEO1:03:45 Linux maintainers are overwhelmed as AI finds thousands of security bugs1:04:28 GoPro pivots toward defense robotics and aerospaceLAW / PRIVACY1:04:52 US government backs OpenAI in its fight with The New York Times1:05:30 Meta bricks smart glasses when users disable the recording light1:06:15 Bernie Sanders proposes banning artificial superintelligenceARTS / CULTURE1:07:53 Former VFX executive says 75% of VFX jobs could vanish1:08:35 ChatGPT 6 helps storyboard, previsualize, and generate a movie1:09:46 AI models can now build their own creative toolsWEIRD / FUNNY1:10:10 Human wins AI art competition — then gets disqualified for being human1:10:55 ChatGPT 6 prepares a tax return…and underpays the governmentEach week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (Creator SMBC Comics, Co-Author of several NYTimes best sellers including A City on Mars and Soonish) as we delve into the latest in AI and Tech News.




