Oxycodone also is known as Roxicodone or as the extended release abuse deterrent formulations Oxycontin and Xtampza. The most common use for oxycodone is in the treatment of moderate to severe pain. When treating patients it is important to determine if the patient is opioid-naïve or opioid experienced. Opioid-naïve patients are doses at the lowest effective dose for the shortest effective duration. Initiating dosing is around 5-15 mg PO q4-6h prn. Opioid-experienced patients are dosed based on their current opioid intake and converted using the most current nomograms. There are multiple black box warnings and extreme caution and monitoring should be exercised when prescribing. The most common side effects are constipation, dizziness, fever, anxiety and confusion. Some serious side effects are abuse, dependency, seizures, and respiratory depression.

 

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