DiscoverAlexander Disease Research UpdateAlexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies
Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Update: 2022-09-01
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Albee Messing, Rachel Battaglia, and Abby Olsen discuss the following recent publication: 

[01:00 ]        Alexander disease GFAP R239C mutant shows increased susceptibility to lipoxidation and elicits mitochondrial dysfunction and oxidative stress (Redox Biology, 55:10 2415, 2022)

[14:23 ]       Questions from email regarding 1) dizziness and 2) risks of brain biopsies. 

Send your questions and feedback to:  axdrupodcast@waisman.wisc.edu

Help support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center:

 

          https://alexander-disease.waisman.wisc.edu/donate/

 

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Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Albee Messing