Alexander Disease Research Update - Episode #15: subclassifications of Type I; questions regarding 1) mesenchymal stem cells and 2) the intransasal route of delivery

Alexander Disease Research Update - Episode #14: whole exome/genome sequencing; more questions on the brainstem

Alexander Disease Research Update - Episode #13: MRI diffusion tractography - what can it tell us?

Alexander Disease Research Update - Episode #12: GFAP variants and oxidative stress/mitochondrial dysfunction; commentary on dizziness, risks of brain biopsies

Alexander Disease Research Update - Episode #11: neurology 101 (location, location, location), discussion on the autonomic nervous system

Alexander Disease Research Update - Episode #10: effects of variants in the rod domain on GFAP assembly and aggregation, new ideas about functions of intermediate filaments

Alexander Disease Research Update - Episode #9: new mechanisms of astrocyte dysfunction, case report with novel variant, commentary on head trauma as an aggravating factor

Alexander Disease Research Update - Episode #8 - two case reports, natural history study of 21 pediatric patients, management of constipation

Alexander Disease Research Update - Episode #7 - common drugs tested in cell culture model; germline mosaicism vs de novo variants; electronic health records in research

Alexander Disease Research Update - Episode #6 - silent mutations, case report, new rat model, mouse proteomics

Alexander Disease Research Update - Episode #5 - case report with silent mutation and area postrema syndrome; neuropsychological testing

Alexander Disease Research Update - Episode #4 - case report, clinical trials

Alexander Disease Research Update - Episode #3: crossing the blood-brain barrier

Alexander Disease Research Update - Episode #2: tumor-like lesions; very-late onset

Alexander Disease Research Update - Episode #1: genetic anticipation?