DiscoverHealth FactsBreakdown of Kreb's Cycle (Guided Approach)
Breakdown of Kreb's Cycle (Guided Approach)

Breakdown of Kreb's Cycle (Guided Approach)

Update: 2023-06-04
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Now, let's break down the Krebs cycle into its key stages and highlight the main reactions that take place:



  1. Acetyl-CoA Formation:
    The cycle begins when a two-carbon molecule called acetyl-CoA combines with a four-carbon molecule called oxaloacetate, forming a six-carbon molecule known as citrate. This step is catalyzed by the enzyme citrate synthase.



  2. Citrate Isomerization:
    The citrate molecule then undergoes a series of rearrangements, resulting in its isomerization into isocitrate. This conversion is facilitated by the enzyme aconitase.


    Listen to learn more!



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Breakdown of Kreb's Cycle (Guided Approach)

Breakdown of Kreb's Cycle (Guided Approach)

Mike Colella, MS