Can RNA provide a way to look for cancer recurrence? Elizabeth Tracey reports
Update: 2025-10-13
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Using blood tests to look for cancer and cancer recurrence has been an area of active research for some time now, with a new study pointing to RNA rather than DNA for detection. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says well, maybe.
Nelson: Way to view RNA it's a working copy of the blueprints that's delivered to the manufacturing site so that the protein components can be made. When they make the RNA they make many copies of it so it will be easier to detect RNA. When you detect it tells you that that gene product is being made. If it's a mutant gene driving the cancer because it's being made. What this group did is they looked at 2200 cases where they did RNA sequencing and DNA sequencing and they believed that they generated useful information for about 87% of the cases. :32
Nelson does believe blood tests for cancer monitoring will soon be practical. At Johns Hopkins, I’m Elizabeth Tracey.
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