Colts' Pass Defense Vulnerable vs 49ers

Colts' Pass Defense Vulnerable vs 49ers

Update: 2025-12-18
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In this weeks football showdown, the Indianapolis Colts defense faces a significant challenge against the San Francisco 49ers, due to key injuries. Starters like DeForest Buckner, Charvarius Ward, and Sauce Gardner are out, leaving the team to rely on less experienced players. While the Colts run defense remains strong, their pass defense has struggled, ranking nineteenth. This sets up a favorable matchup for the 49ers quarterback Brock Purdy, who could use this game as a stepping stone for upcoming tougher opponents.

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Colts' Pass Defense Vulnerable vs 49ers

Colts' Pass Defense Vulnerable vs 49ers