Dr. Edgardo Santos' Interview with Mark Matrana, MD, MS, FACP
Update: 2025-08-25
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Interviews with Summit Director Edgardo S. Santos Castillero, MD, FACP, FASCO
NOSCM 2024 | New Orleans Summer Cancer Meeting
Dr. Edgardo Santos' Interview with Mark Matrana, MD, MS, FACP
Dr. Matrana highlighted two new gene‐based therapies foradvanced bladder cancer—a non-replicating adenovirus delivering interleukin and a replicating virus combined with pembrolizumab—and noted that the Afrin + pembrolizumab regimen outperformed chemotherapy in metastatic urothelial carcinoma, albeit with toxicities like neuropathy, ocular issues, hyperglycemia, and rash. He also pointed to upcoming strategies pairing immunotherapy with chemotherapy and using circulating tumor DNA to guide monitoring and treatment adjustments.
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