Guest:

Dr. Tamara Tilburgs is an Assistant Professor in the University of Cincinnati Department of Pediatrics, where her research focuses on immune tolerance during pregnancy. She talks about the immune paradox in trophoblast cells and how placental inflammation can lead to pregnancy complications. She also discusses CD8⁺ T cell responses at the maternal-fetal interface. (43:03 )

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The Immunology Round Up

Non-Antibiotics and Enteropathogens – Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens. (1:38 )

Medications and the Gut Microbiome – An analysis of prescription medications shows that several non-antibiotic drugs, such as the heart medication digoxin, can increase the risk of gastrointestinal infections. (7:20 )

Sex Dimorphism in Immune Responses – Fine-tuning of type 2 immune responses may explain why females are more susceptible to allergies. (15:00 )

Transposable Elements in Tregs – Researchers identified DNA methylation, chromatin accessibility, and gene expression programs that govern the tissue adaptation of human skin Treg cells. (28:10 )

Image courtesy of Dr. Tamara Tilburgs