Visit pointofcaremedicine.com to see the templates, pearls, literature, and other resources discussed in this episode.

Our mission is to create accessible and easy-to-use digital resources that help healthcare professionals tackle common clinical presentations at the point of care, without getting bogged down by unnecessary details or trivia.

Show Notes:

00:00:15 - Introduction and Terminology

00:01:51 - Beta Blockers

00:02:47 - ACE/ARB/ARNI

00:04:30 - MRA's

00:05:28 - SGLT2i's

00:06:12 - Nitrates and Hydralazine

00:08:41 - Loop Diuretics

00:09:25 - Initiating and Titrating GDMT

00:11:18 - Barriers and Other Considerations

00:13:44 - Resources for Use at the Point of Care

Other Resources and References:

GDMT for Everyone – https://www.gdmt.org/HFrEF.php

Table of all the Sacubitril/Valsartan Trials Published to Date (2023) - https://twitter.com/jaycvance/status/1660732176999108623

An elegant graphic showing how the hazard ratios with confidence intervals for all-cause mortality improve based on adding on each extra GDMT medication; brought to my attention by a tweet from Dr. Scott Cameron - ⁠https://twitter.com/2Scottish/status/1556798319996932096⁠

Heart Failure with Reduced Ejection Fraction: A Review (JAMA, 2020) - https://pubmed.ncbi.nlm.nih.gov/32749493/

A Systematic Review and Network Meta-Analysis of Pharmacological Treatment of Heart Failure With Reduced Ejection Fraction (JACC, 2022) -
⁠https://www.jacc.org/doi/full/10.1016/j.jchf.2021.09.004