In Part 2 of our deep dive into GLP-1s, we continue our conversation with Dr. Elroy Vojdani to explore the questions everyone is asking but few experts are willing to answer. This episode goes beyond weight loss to uncover how GLP-1 medications intersect with women’s health, hormones, longevity, and the natural aging process.

We break down microdosing, natural GLP-1 alternatives, and what women need to consider if they’re taking these drugs without a clinical need. Dr. Vojdani sheds light on tricky topics like COVID and GLP-1 interactions, endometriosis and PCOS, hormone absorption issues, and whether these medications impact bone density, muscle mass, hot flashes, mood, or sleep during menopause and perimenopause.

We also tackle the big question: what are the real downsides? From gallbladder risks and pancreatitis to gut-motility concerns and what actually happens when someone stops taking these medications, this conversation is packed with the latest research from a functional medicine lens.

Links: 

Regenera Medical - https://www.regeneramedical.com

Subtack - https://theinflamedgeneration.substack.com

Timecodes:

00:30 — Microdosing GLP-1s
02:13 — What about women taking GLP-1s who don’t medically need them?
03:29 — Natural GLP-1 alternatives
05:40 — COVID, vaccines, and GLP-1s
08:29 — The intersection between GLP-1s and menopause/perimenopause
09:29 — Endometriosis, PCOS, and GLP-1s
12:29 — Possible issues with oral hormone therapy absorption while on GLP-1s
13:29 — Do women need to protect bone density and muscle mass more while on GLP-1s?
15:29 — Links between GLP-1 use and hot flashes, mood changes, and sleep quality during perimenopause/menopause
17:09 — So… what are the downsides?
17:29 — What are normal aging mechanisms in the body, and could GLP-1s potentially accelerate them?
18:29 — How concerned should people be about gallbladder issues, pancreatitis, gut motility problems, etc.?
22:15 — What happens when someone stops taking them?