DiscoverCell & Gene: The PodcastGene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath
Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath

Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath

Update: 2025-07-03
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In this episode of Cell & Gene: The Podcast, George Magrath, CEO of Opus Genetics, shares with Host, Erin Harris, how the company is advancing gene therapies for inherited retinal diseases (IRDs), with a focus on LCA5, a rare and severe form of childhood blindness. Built on the foundational science of Dr. Jean Bennett and leveraging the legacy of Luxturna, Magrath shares how Opus is developing subretinal AAV-based therapies targeting seven distinct mutations. He also explains why gene therapy is particularly well-suited to IRDs, shares compelling early clinical data, and discusses the promise of early intervention in preserving vision and enabling proper neural development. 

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Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath

Gene Therapy for Inherited Retinal Diseases with Opus Genetics' Dr. George Magrath

Erin Harris