Genetic risk factors for Alzheimer's disease with Prof. Julie Williams
Update: 2025-06-27
Description
In this episode of our Neuroscience Research series, Filippo Dall'Armellina and Dr Michael Cearns speak with Professor Julie Williams (Cardiff University), a leading figure in the genetics of Alzheimer’s disease. Prof. Williams also co-hosts “In Two Minds” with Justine Pickering, so be sure to check it out.
Research highlights:
- Paper 1: Harold D et al. (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer’s disease. Nature Genetics. [PMID: 19734902].
- Paper 2: Sims R et al. (2017). Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease. Nature Genetics. [PMID: 28714976].
Research highlights:
- Paper 1: Harold D et al. (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer’s disease. Nature Genetics. [PMID: 19734902].
- Paper 2: Sims R et al. (2017). Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease. Nature Genetics. [PMID: 28714976].
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