E5   |   14 min   |   Latest   |  Publication Source   

• Podcast based on: Sipos D, Raposa BL, Freihat O, Simon M, Mekis N, Cornacchione P, Kovács Á. Glioblastoma: Clinical Presentation, Multidisciplinary Management, and Long-Term Outcomes. Cancers. 2025; 17(1):146. https://doi.org/10.3390/cancers17010146
  
  Type: Review  |  Publication date: Jan 5, 2025
  
  
  
  


• Summary: This document comprehensively examines glioblastoma, the most aggressive form of brain cancer. It details the disease's diagnosis, utilising advanced imaging and molecular markers like IDH mutation and MGMT methylation status for prognosis. Standard treatment, involving surgery, radiation, and chemotherapy (temozolomide), is discussed alongside emerging therapies such as TTFields and immunotherapies. The text also addresses the importance of managing symptoms and providing psychological support for patients and their families to improve quality of life, while acknowledging the ongoing need for research and clinical trials to improve outcomes. Finally, typical survival rates and factors influencing prognosis are presented.
  
  
  
  


• Keywords: glioblastoma; prognosis; treatment; survival; outcome

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