In this episode, Dr. Brandon and Dr. Morgentaler talk about the groundbreaking moments that defined Dr. Morgentaler's career—from challenging long-held medical dogmas about testosterone and prostate cancer to reflecting on courage, science, and the evolving state of modern medicine.

00:00 – Introduction and Lifetime Achievement Award
In this episode, Dr. Brandon and Dr. Morgentaler talk about his Lifetime Achievement Award and reflect on the meaning of being recognized by peers after decades in sexual medicine.

03:13 – Early Career and Groundbreaking Research
They discuss how Dr. Morgentaler's early curiosity about testosterone—from lizard studies at Harvard to treating men others wouldn't—sparked discoveries that reshaped urology.

08:49 – Challenges and Controversies in Urology
Dr. Morgentaler recalls standing firm against public criticism from leading urologists as he presented data that contradicted long-held beliefs about testosterone and cancer.

25:03 – Facing the Hardest Moments in Surgery
He opens up about the emotional toll of surgical complications and the weight of caring deeply for patients while maintaining composure under pressure.

28:22 – Breakthroughs in Prostate Cancer Treatment
They explore his bold use of testosterone therapy—even for men with advanced cancer—and how it restored vitality and meaning for patients once written off.

36:30 – Challenging Medical Dogma
Dr. Morgentaler reflects on why medicine resists new evidence, the persistence of outdated myths, and how progress in science often advances one funeral at a time.

Resources:
1. Morgentaler, A., Bruning, C. O., & DeWolf, W. C. (1996). Occult prostate cancer in men with low serum testosterone levels. JAMA, 276(23), 1904–1906. https://doi.org/10.1001/jama.1996.03540230040029

2. Morgentaler, A., & DeWolf, W. C. (1997). Implantation of penile prosthesis at the time of radical prostatectomy: A new approach for erectile rehabilitation. Urology, 49(6), 932–936. https://doi.org/10.1016/S0090-4295(97)00127-4

3. Lincoff, A. M., Nissen, S. E., Krum, H., et al. (2023). Cardiovascular safety of testosterone-replacement therapy. New England Journal of Medicine, 389(6), 514–524. https://doi.org/10.1056/NEJMoa2301761

With Dr. Abraham Morgentaler and Dr. Marianne Brandon

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