DiscoverLeading Beyond The LabHow Maxion’s KnotBody® Platform Is Changing the Way We Treat the ‘Undruggable’
How Maxion’s KnotBody® Platform Is Changing the Way We Treat the ‘Undruggable’

How Maxion’s KnotBody® Platform Is Changing the Way We Treat the ‘Undruggable’

Update: 2025-09-02
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Dr. Arndt Schottelius, CEO of Maxion Therapeutics, is a physician-scientist with a standout career across Genentech, MorphoSys, Kymab, and now at one of the UK’s most promising biotech companies. At Maxion, he leads a team pioneering KnotBody technology - an innovative approach to targeting ion channels and GPCRs, long considered “undruggable” with biologics. Arndt brings more than 25 years of experience across translational science, drug development and leadership in global R&D. His conviction, clarity, and track record - including developing molecules that have become partnered, acquired and approved - makes this conversation a must-listen for anyone in life sciences leadership.


In this episode, we cover:

  • How Maxion is building a new therapeutic modality using KnotBody technology to tackle autoimmune and inflammatory diseases
  • Why conviction, speed, and storytelling are non-negotiable in translational drug development
  • Lessons from Genentech, MorphoSys, and Kymab on building pipelines, teams, and partnerships
  • What investors really look for - and how Maxion secured a competitive Series A in a tough market
  • How to hire and scale for scientific excellence without losing agility or collaboration


Tune in for a dynamic, insightful conversation with one of biotech’s most experienced and thoughtful leaders.


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Arndt Schottelius

CEO at Maxion Theraprutics

LinkedIn: https://www.linkedin.com/in/arndt-schottelius-md-ph/


Lawrence Rose

Co-Founder + Talent Solutions Director At ARTO

LinkedIn: https://www.linkedin.com/in/lawrencerose/


Timestamps:

00:00 Career Beginnings

06:46 Translational Science

08:55 Lessons in Biotech Leadership

25:23 Maxion - Culture and Roundup


#LeadingBeyondTheLab #ARTOTalent #Biotechnology 


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How Maxion’s KnotBody® Platform Is Changing the Way We Treat the ‘Undruggable’

How Maxion’s KnotBody® Platform Is Changing the Way We Treat the ‘Undruggable’