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Lymphoid gene expression supports neuroprotective microglia function

Lymphoid gene expression supports neuroprotective microglia function

Update: 2025-12-06
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This article "Lymphoid gene expression supports neuroprotective microglia function" is published in Nature.


Author: Pinar Ayata

Journal: Nature

Year: 2025

Podcast type: Short


The authors are:


⦁ Pinar Ayata

⦁ Jessica M. Crowley

⦁ Matthew F. Challman

⦁ Vinaya Sahasrabuddhe

⦁ Maud Gratuze

⦁ Sebastian Werneburg

⦁ Diogo Ribeiro

⦁ Emma C. Hays

⦁ Violeta Durán-Laforet

⦁ Travis E. Faust

⦁ Philip Hwang

⦁ Francisco Mendes Lopes

⦁ Chrysa Nikopoulou

⦁ Sarah Buchholz

⦁ Robert E. Murphy

⦁ Taoyu Mei

⦁ Anna A. Pimenova

⦁ Carmen Romero-Molina

⦁ Francesca Garretti

⦁ Tulsi A. Patel

⦁ Claudia De Sanctis

⦁ Angie V. Ramirez Jimenez

⦁ Megan Crow

⦁ Felix D. Weiss

⦁ Jason D. Ulrich

⦁ Edoardo Marcora

⦁ John W. Murray

⦁ Felix Meissner

⦁ Andreas Beyer

⦁ Dan Hasson

⦁ John F. Crary

⦁ Dorothy P. Schafer

⦁ David M. Holtzman

⦁ Alison M. Goate

⦁ Alexander Tarakhovsky

⦁ Anne Schaefer


Affiliations:


Pinar Ayata, Jessica M. Crowley, Matthew F. Challman, Vinaya Sahasrabuddhe, Diogo Ribeiro, Emma C. Hays, Philip Hwang, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Edoardo Marcora, John F. Crary, Alison M. Goate, Anne Schaefer ,Nash Family Department of Neuroscience, Department of Psychiatry, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Pinar Ayata, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Edoardo Marcora, John F. Crary, Alison M. Goate, Anne Schaefer,Ronald M. Loeb Center for Alzheimer’s Disease, Center for Glial Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Pinar Ayata,Neuroscience Initiative, Advanced Science Research Center, Graduate Program in Biology, Graduate Program in Biochemistry, Graduate Program in Neuroscience, The City University of New York Graduate Center, New York, NY, USA.

Maud Gratuze, Jason D. Ulrich, David M. Holtzman,Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.

Maud Gratuze,Institute of Neurophysiopathology (INP), University of Aix-Marseille, CNRS UMR 7051, Marseille, France.

Sebastian Werneburg, Violeta Durán-Laforet, Travis E. Faust, Robert E. Murphy, Dorothy P. Schafer,Department of Neurobiology, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Sebastian Werneburg,Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, Michigan Neuroscience Institute, Department of Molecular & Integrative Physiology, University of Michigan, Michigan Medicine, Ann Arbor, MI, USA.

Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Anne Schaefer,Max Planck Institute for Biology of Ageing, Cologne, Germany.

Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Taoyu Mei, Andreas Beyer,Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

Taoyu Mei, Andreas Beyer,Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.

Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Edoardo Marcora, Alison M. Goate,Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Claudia De Sanctis, John F. Crary,Department of Pathology, Department of Artificial Intelligence & Human Health, Neuropathology Brain Bank and Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Angie V. Ramirez Jimenez, Dan Hasson,Bioinformatics for Next-Generation Sequencing (BiNGS) Core, Tisch Cancer Institute, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Megan Crow,Department of Human Genetics, Genentech Inc., South San Francisco, CA, USA.

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Lymphoid gene expression supports neuroprotective microglia function

Lymphoid gene expression supports neuroprotective microglia function

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