Dr. Brooke Britton discusses degranulation events—a scary potential when a dog has mast cell tumors. Learn what degranulation is, why it happens, and how it can affect your dog. Also: practical tips for managing symptoms, potential connections between allergies and cancer, and how to care for dogs with mast cell tumors.

Topics Discussed:

• What is a degranulation event?

• How mast cell tumors cause degranulation

• Symptoms dogs may experience during a degranulation event

• The role of allergies and chronic inflammation in mast cell tumor risk

• Medications and treatments to manage symptoms

• Low-histamine diets and their role in comfort care

• Tips for preventing future mast cell tumor growth

• The importance of early detection and regular vet check-ups

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Related Videos:

https://www.youtube.com/watch?v=Al7jjCXVhuE

https://www.youtube.com/watch?v=6eb4GrcH_f8

Related Links:

Our article on mast cell tumors: https://www.dogcancer.com/articles/types-of-dog-cancer/mast-cell-tumors-in-dogs/

Chapters:

00:00  Introduction

01:15 What Are Mast Cell Tumors?
02:30 The Role of Mast Cells in Normal Immune Response
04:00 What Happens During a Degranulation Event?
06:45 Symptoms Dogs May Experience During Degranulation
09:00 How Dogs Might Feel During Degranulation Events
11:00 Stomach Upset and Ulcers in Dogs with Mast Cell Tumors
13:00 The Link Between Allergies and Mast Cell Tumors
16:00 Managing Allergies in Dogs to Reduce Risk
18:30 Diet Considerations: Low-Histamine and Commercial Diets
22:00 Medications for Degranulation Symptoms: Benadryl and Tagamet
25:00 The Truth About Diet and Cancer Prevention
27:30 Why Balanced Diets Are Key for Dogs with Cancer
29:45 Closing Thoughts on Degranulation and Mast Cell Tumors
34:00 Outro: Support and Resources for Dog Owners

Get to know Dr. Brooke Britton: https://www.dogcancer.com/people/brooke-britton-dvm-dacvim-oncology/   

For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/

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