Master USMLE: Diagnosing Hepatitis C — Don't Skip the RNA Test
Description
Welcome back, Master Series followers.
In this high-yield Step 2 CK episode, we walk through a common yet misunderstood scenario — a patient with a positive hepatitis C antibody test. What comes next? Should you treat? Order a biopsy? Start imaging?
We break down how to confirm chronic hepatitis C, when to order HCV RNA, and why a positive antibody alone is never enough. This case highlights key risk factors like past IV drug use, alcohol intake, and obesity — and guides you through the exact sequence of testing and management.
Master the difference between exposure vs. active infection, avoid common traps on the exam, and solidify your approach to liver disease evaluation.
By the end of this episode, you’ll confidently know: – When to order HCV RNA
– Why not to jump into treatment
– How to interpret hepatitis B serologies
– What makes liver biopsy outdated
– Why lifestyle still matters even without active hepatitis
Stay sharp. Study smart. Keep mastering your craft.
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