In this episode, I had the pleasure of sitting down with Nicolas Verhoeven of Physionic. We focus our attention on metabolic health and, specifically, the energy-related, cellular, and nutritional mechanisms of insulin resistance. Nicolas reviews evidence pertaining to the reversal of insulin resistance and dietary clinical trials demonstrating remission of type 2 diabetes. Nicolas also highlights the synergistic effects of physical activity and dietary habits on insulin resistance, expanding our discussion into mitochondrial health. Finally, we explore importance of a nuanced conversation around autophagy and its role in health and disease prevention.

Physionic on YouTube:
https://www.youtube.com/@Physionic

Chapters:

00:00:13 - Nicolas' Background & Inspiration
00:05:34 - Misconceptions about Carbs & Fat Intake
00:08:57 - Mechanisms of Insulin Resistance
00:18:34 - Reversing Insulin Resistance & Diabetes
00:23:08 - Measuring Insulin Resistance
00:24:20 - Continuous Glucose Monitoring (CGM)
00:30:25 - Insulin Resistance & Health
00:37:33 - Mitochondrial Dysfunction
00:49:14 - Mitochondrial Biogenesis
00:56:05 - Improving Mitochondrial Health
01:02:54 - Autophagy
01:07:28 - Closing Remarks

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References & Show Notes:
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The content of this podcast is not medical advice, is for general information purposes only, and does not constitute the practice of medicine or any other healthcare professional services. No doctor-patient relationship is formed. The content of this podcast is not a substitute for medical evaluation or treatment and does not take precedence over information provided to you by your healthcare provider or official public health sources. Please visit nicksterling.com/terms for full Terms of Use.