にゃんごう＆いがさんのEBMerな夜

第91回放送　2024/7/2

【にゃんごう：妊婦のメトホルミン】

Chiu YH, Huybrechts KF, Patorno E, Yland JJ, Cesta CE, Bateman BT, Seely EW, Hernan MA, Hernandez-Diaz S.

Metformin Use in the First Trimester of Pregnancy and Risk for Nonlive Birth and Congenital Malformations: Emulating a Target Trial Using Real-World Data.

Ann Intern Med. 2024 Jun 18. doi: 10.7326/M23-2038. Epub ahead of print.

PMID: 38885505.

https://www.acpjournals.org/doi/10.7326/M23-2038

【いがさん：抗菌薬の持続投与】

Dulhunty JM, Brett SJ, De Waele JJ, Rajbhandari D, Billot L, Cotta MO, Davis JS, Finfer S, Hammond NE, Knowles S, Liu X, McGuinness S, Mysore J, Paterson DL, Peake S, Rhodes A, Roberts JA, Roger C, Shirwadkar C, Starr T, Taylor C, Myburgh JA, Lipman J; BLING III Study Investigators.

Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial.

JAMA. 2024 Jun 12:e249779. doi: 10.1001/jama.2024.9779. Epub ahead of print.

PMID: 38864155; PMCID: PMC11170452.

https://jamanetwork.com/journals/jama/article-abstract/2819971

Abdul-Aziz MH, Hammond NE, Brett SJ, Cotta MO, De Waele JJ, Devaux A, Di Tanna GL, Dulhunty JM, Elkady H, Eriksson L, Hasan MS, Khan AB, Lipman J, Liu X, Monti G, Myburgh J, Novy E, Omar S, Rajbhandari D, Roger C, Sjovall F, Zaghi I, Zangrillo A, Delaney A, Roberts JA.

Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock: A Systematic Review and Meta-Analysis.

JAMA. 2024 Jun 12:e249803. doi: 10.1001/jama.2024.9803. Epub ahead of print.

PMID: 38864162; PMCID: PMC11170459.

https://jamanetwork.com/journals/jama/article-abstract/2819970

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