Join host Eoin Tabb on the Irish Haematology Oncology Podcast as he delves into the critical role of ancillary medications in chemotherapy. This episode focuses on essential supportive care drugs like vitamins, steroids, and hydration protocols, highlighting their mechanisms, administration, and importance in mitigating side effects and optimizing treatment outcomes. Learn about:

• Hydration in cisplatin and methotrexate regimens


• Folinic acid rescue in high-dose methotrexate treatment


• Mesna prophylaxis for hemorrhagic cystitis in cyclophosphamide and ifosfamide regimens


• Practical tips for managing common chemotherapy side effects

2. Podcast Show Notes:

• Hydration Protocols: The importance of maintaining adequate fluid intake before, during, and after chemotherapy to protect kidney function and minimize toxicity.


• Cisplatin and Nephrotoxicity: The risks of kidney damage associated with cisplatin and the specific hydration strategies used to mitigate these risks.


• Methotrexate and Folinic Acid: The combined use of hydration, alkalinization, and folinic acid rescue to prevent kidney damage and protect healthy cells from methotrexate's effects.


• Hemorrhagic Cystitis: The role of mesna in preventing bladder inflammation and bleeding caused by cyclophosphamide and ifosfamide.


• Practical Tips: Additional strategies for managing common side effects like nausea, vomiting, diarrhea, and fatigue.

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IIOP Education Document (same as last episode): https://docs.google.com/document/d/1d1KEtJ6yrZ_fMGMLgTFgQ762rX0-y5vbb4ikDsr_U6s/edit?usp=sharing