DiscoverCCO Oncology PodcastTROP2 and TIGIT Therapies for Advanced NSCLC: Where Are We Today?
TROP2 and TIGIT Therapies for Advanced NSCLC: Where Are We Today?

TROP2 and TIGIT Therapies for Advanced NSCLC: Where Are We Today?

Update: 2025-11-18
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Description

In this episode, Benjamin Levy, MD, FASCO, and Alex Spira, MD, PhD, FASCO, discuss the latest developments in targeting TROP2 and TIGIT for the treatment of lung cancer, including:

  • TROP2-targeting ADCs: datopotamab deruxtecan, sacituzumab govitecan, sacituzumab tirumotecan 
  • TROP2 ADCS for patients with EGFR-mutated NSCLC
  • TIGIT-targeting agents: domvanalimab, rilvegostomig

Presenters:

Benjamin Levy, MD, FASCO
Associate Professor
Johns Hopkins School of Medicine
Clinical Director
Johns Hopkins Kimmel Cancer Center, National Capitol Region (NCR)
Washington, DC

Alex Spira, MD, PhD, FASCO
Director Clinical Research
Virginia Cancer Specialists
CEO NEXT Oncology Virginia
Fairfax, Virginia

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program:
https://bit.ly/4qZLR6B


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TROP2 and TIGIT Therapies for Advanced NSCLC: Where Are We Today?

TROP2 and TIGIT Therapies for Advanced NSCLC: Where Are We Today?

Benjamin Levy MD FASCO, Alex Spira MD PhD FASCO