The Entrepreneur's Guide to Healing Trauma and Nervous System Regulation | Jesse Harless
Update: 2025-08-30
Description
Timestamps
- 00:01 - Introduction and Jesse's background in recovery and entrepreneurship
- 01:44 - The origin story: childhood trauma and father's abandonment at age 3
- 06:41 - Rock bottom at 22: federal drug charges and court-ordered therapy
- 09:56 - The power of co-regulation and finding an empathetic witness
- 13:00 - Practical skills for holding space and developing presence
- 16:57 - Understanding addiction as a spectrum beyond substances
- 21:57 - Jesse's journey into psychedelic-assisted therapy after 15 years abstinent
- 27:11 - Respecting psychedelics: safety, preparation, and integration
- 32:13 - How your nervous system runs the show without your permission
- 37:52 - Morning routines and the transformative power of crying
- 43:15 - Dopamine addiction and reclaiming attention from technology
- 50:43 - The correlation between trauma, addiction, and entrepreneurship
- 56:15 - Breaking free from rigid identity and discovering new desires
- 58:25 - Where to connect with Jesse and his work
Jesse Harless is a psychedelic experience curator, keynote speaker, therapist, nervous system coach, and bestselling author of "If Not You Then Who" and "Smash Your Comfort Zone with Cold Showers." He holds a master's degree in clinical mental health counseling and hosts the Entrepreneurs in Recovery podcast. After facing federal drug charges at 22, Jesse transformed his life and now specializes in trauma-informed healing, working with heart-centered leaders and purpose-driven organizations.
In this episode, we explore:
- The transformation journey - How Jesse went from standing before a federal judge for narcotics possession to becoming a leader in recovery and mental health, including the pivotal role of his court-appointed therapist
- Trauma, addiction, and entrepreneurship - The surprising connection between early wounding and high achievement, why 85% of successful people struggle with addiction, and how trauma can become your greatest business asset
- Nervous system regulation mastery - Practical tools for understanding when your stress response is running the show, morning routines that actually work, and why crying might be your most underutilized healing tool
- Psychedelic-assisted therapy insights - Jesse's four-year research journey into psychedelics, the importance of respect and preparation, and how these medicines fit into broader mental health treatment
Resources & Connect with Jesse:
-Website: jessiharless.com-Podcast: Entrepreneurs in Recovery (Spotify, YouTube)-Books: "If Not You Then Who" and "Smash Your Comfort Zone with Cold Showers"
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