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Welcome to AACE podcasts! Tune in as we elevate clinical endocrinology by taking deep dives into trends and topics that can help us improve our patient care and global health. Created by clinical endocrine experts for healthcare professionals. Topics include thyroid, diabetes, obesity, adrenal, and more. Find the latest episodes on AACE.com/podcasts. Copyright American Association of Clinical Endocrinology.
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Join endocrine expert Janet B. McGill, MD, MA, FACE, FACP, Professor of Medicine in the Division of Endocrinology, Metabolism and Lipid Research at Washington University School of Medicine, and moderator Sina Jasim, MD, MPH, ACCR Editor-in-Chief, Associate Professor of Medicine, and Endocrine Neoplasia Specialist at Washington University School of Medicine, as they discuss diabetes clinical case reports from the July/August 2023 issue of ACCR. Dr. McGill presents two key cases, MODY5 and Serous Ovarian Carcinoma in 17q12 Recurrent Deletion Syndrome, — a case of a young woman whose monogenic diabetes was diagnosed after a pathogenic ~1.8 Mb loss of 17q12 was found on the chromosomal microarray of her serous ovarian carcinoma and identifying a disease association not previously reported. The second case was on the maturity-onset of diabetes of the young (MODY), ABCC8-Related Monogenic Diabetes Presenting Like Type 1 Diabetes in an Adolescent, — a case of type 1 diabetes diagnoses during adolescence, and how the patient was treated with intensive insulin therapy for 17 years before genetic testing showed a pathogenic mutation of the ABCC8 gene. Access the key teaching points and view the full cases of MODY5 and Serous Ovarian Carcinoma in 17q12 Recurrent Deletion Syndrome at: https://www.aaceclinicalcasereports.com/article/S2376-0605(23)00093-7/fulltext and ABCC8-Related Monogenic Diabetes Presenting Like Type 1 Diabetes in an Adolescent at: https://www.aaceclinicalcasereports.com/article/S2376-0605(23)00086-X/fulltext
Parathyroid cysts (PC) are a rare cause of neck masses, with an ectopic intrathyroidal location being even rarer. Join endocrine experts Victor J. Bernet, MD, FACE, FACP, Director, Endocrinology, Diabetes and Metabolism Fellowship Program at the Mayo Clinic in Florida, and Sina Jasim, MD, MPH, ACCR Editor-In-Chief, Associate Professor of Medicine, and Endocrine Neoplasia Specialist at Washington University School of Medicine, as they discuss the clinical case report, A Middle-aged Woman With Recurrent Intrathyroidal Parathyroid Cyst Treated With Ethanol Sclerotherapy, which presents a case of a recurrent intrathyroidal cyst successfully treated with ethanol sclerotherapy. Key topics discussed include the sclerosis efficacy in orthotopically positioned PCs, how ethanol sclerotherapy is an effective treatment option for recurrent intrathyroidal PCs, and important teaching points of this case. Visit https://www.aaceclinicalcasereports.com/article/S2376-0605(23)00131-1/fulltext to read the full AACE Clinical Case Report.
Join clinical experts David Lieb, MD, FACE, Jennifer N. Clements, PharmD, FCCP, FADCES, BCPS, CDCES, BCACP, BC-ADM, and Vin Tangpricha, MD, PhD, FACE, as they discuss the 2022 AACE diabetes guideline updates and address the issue, “How Should Hypoglycemia Be Managed?” Key topics include how to put the guideline into practice particularly in primary care settings, how to characterize which people with diabetes should be prescribed glucagon to manage low blood sugar levels, and how to incorporate ready-to-use glucagon into hypoglycemia treatment plans for people with diabetes. Support for this podcast is provided by Xeris Pharmaceuticals, Inc.
Minimally invasive procedures are now more widely used for benign and some low-risk cancerous thyroid tumors. In certain cases of papillary thyroid microcarcinomas; and if those are positioned in a favorable location, Radiofrequency Ablation (RFA) offers a less invasive treatment option compared to traditional surgical approaches. Listen to Leonardo Guimarães Rangel, MD, Head and Neck Surgeon in Rio de Janeiro, Brazil, and international expert in minimally invasive procedures in thyroid tumors, present his Visual Vignette on Radiofrequency Ablation of Papillary Thyroid Microcarcinomas, moderated by Sina Jasim, MD, MPH, Associate Professor of Medicine, and Endocrine Neoplasia Specialist at Washington University School of Medicine. Key topics include procedure safety, determining the right patient and nodule candidate, follow-up care, challenges, and future outcomes. Visit https://www.aaceclinicalcasereports.com/article/S2376-0605(22)00010-4/fulltext to view and read the full AACE Visual Vignette.
Join endocrine experts Ricardo Correa, MD, FACP, FACMQ, FAPCR, FACE; Rajesh Garg, MD, PhD; and Geetha Gopalakrishnan, MD, FACE, as they share valuable tips and success stories on how to talk to patients with diabetes about the importance of vaccinations in diabetes management. Key topics include strategies for addressing barriers in workflows, differences in cultural norms and vaccine hesitancy. AACE endocrine experts share available patient resources along with a wealth of information aimed at enhancing your interactions with patients.
AACE has revised its policies and adopted a new methodology for guideline and consensus statement development to support the mission to elevate the practice of clinical endocrinology to improve patient care. Join endocrine experts Ricardo Correa, MD, FACP, FACMQ, FAPCR, FACE, Joanna Miragaya, MD, PhD, FACE, and Vin Tangpricha, MD, PhD, FACE, as they dive into the 2023 protocol updates. Key topics include updates to methodology, processes, and policies. Visit https://www.endocrinepractice.org/article/S1530-891X(23)00032-0/fulltext to view the protocol in the May 2023 issue of Endocrine Practice.
Wolfram syndrome (WS) is a rare genetic disorder in which patients develop early-onset diabetes mellitus (DM), optic nerve atrophy, and neurodegeneration, which has no specific treatment available. Listen to endocrine experts Fumihiko Urano, MD, PhD. Samuel E. Schechter Professor of Medicine at Washington University School of Medicine, and Sina Jasim, MD, MPH, Associate Professor of Medicine at Washington University School of Medicine, discuss a new clinical case report on two patients with Wolfram syndrome who were initially diagnosed with type 1 diabetes but were negative for islet autoantibodies. Key topics include the importance of distinguishing between Wolfram syndrome and type 1 diabetes, the significance of the homozygous vs. compound heterozygous pathogenic variants in WFS1 gene, how the management and treatment for Wolfram syndrome differs from that of type 1 diabetes, the current status of therapeutic interventions, and much more. Visit https://doi.org/10.1016/j.aace.2022.01.001 to read the full AACE Clinical Case Report.
Join endocrine experts Karl Nadolsky, DO, DABOM, and Vin Tangpricha, MD, PhD, FACE, as they discuss the 2023 AACE Consensus Statement: Addressing Stigma and Bias in the Diagnosis and Management of Patients with Obesity/Adiposity-Based Chronic Disease and Assessing Bias and Stigmatization as Determinants of Disease Severity. Key topics include defining weight stigma, bias, and internalized weight bias (IWB), empowering patients and our global society to address obesity as a chronic disease, intervention recommendations using the 5A model, and much more. Visit https://www.endocrinepractice.org/article/S1530-891X(23)00335-X/fulltext to view the consensus statement in the June 2023 issue of Endocrine Practice.
Join endocrine experts Irl Hirsch, MD, Susan L. Samson, M.D., Ph.D., FRCPC, FACE, and Vin Tangpricha, MD, PhD, FACE, as they discuss the latest updates to AACE’s 2023 diabetes algorithm, which provides concise guidance to assist health care professionals in clinical decision-making for the management of Type 2 diabetes (T2D). Learn how to leverage the algorithm to improve patient care, how someone’s risk for hypoglycemia impacts their individual target, when to use a complications-centric and glucose-centric approach to choosing first-line therapy for glycemic control, and much more. Visit https://doi.org/10.1016/j.eprac.2023.02.001 to view the full algorithm in the May 2023 issue of Endocrine Practice.
Nonalcoholic fatty liver disease (NAFLD) is a major health problem that is closely linked to the epidemics of obesity and type 2 diabetes mellitus. Join endocrine experts Betul Hatipoglu MD, Professor of Medicine at CWRU School of Medicine, and Medical Director for Diabetes & Obesity Center at University Hospital Cleveland Medical Center, and Sangeeta Kashyap MD, Assistant Chief of Clinical Affairs at New York-Presbyterian/Weill Cornell Medical Center, to learn how to diagnose and manage NAFLD and NASH in primary care and endocrinology clinical settings. Key topics include screening for NAFLD/NASH, and the latest management recommendations including supplements, medications, bariatric surgery, and more.
In this podcast endocrine expert David C. Lieb, MD, FACP, FACE, interviews our AACE 2023 award-winning plenary speakers, Elizabeth N. Pearce, MD, MSc, FACE, Irl Hirsch, MD, and Richard J. Auchus, MD, PhD, FACE, about the latest advancements in thyroid disease, diabetes, and adrenal disease. Key topics include iodine deficiency, adjusting thyroid medication doses, the future of insulin therapy, GMI compared to A1C levels, screening for primary aldosteronism, Cushing's syndrome, adrenal steroid profiling, and more.
There is varying knowledge among members of the endocrine care team about the vaccines AACE recommends for persons with diabetes that are included in the updated 2022 AACE Diabetes Guideline. In this podcast endocrine expert Vin Tangpricha, MD, PhD, interviews internationally known clinician, epidemiologist, and Interim Dean of Emory University School of Medicine, Carlos del Rio, MD, about the importance of vaccines, how vaccines are made, developed, and approved, and how to use this information to address patients’ questions or hesitancy towards vaccines.
Join endocrine experts S. Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE, Susan L. Samson, MD, PhD, FRCPC, FACE, and Vin Tangpricha, MD, FACE, as they discuss the 2022 AACE diabetes clinical practice guideline featuring 170 updated and new evidence-based recommendations for the care and management of people with or at risk for diabetes mellitus. Key topics include how to use the guideline in your practice, new content developed on hypoglycemia, secondary diabetes approaches, supplements, social determinants of health, and more. Plus, get an inside sneak peek into the development of a diabetes care algorithm coming soon. Visit https://www.endocrinepractice.org/article/S1530-891X(22)00576-6/fulltext to view the full guideline published in the October 2022 issue of Endocrine Practice.
Listen to endocrine experts, Vinni Makin, MD, Joumana Chaiban, MD, and Ricardo Correa, MD, share their personal experiences about how they obtained a visa as international medical graduates and transitioned to practicing medicine in the United States. Key topics include visa requirements, how to apply for a visa, and the benefits of a mentorship program once you transition to the U.S.
For persons with diabetes, vaccinations have been shown to help them from contracting and experiencing more severe outcomes from preventable illnesses, such as influenza and Covid-19.It is important for the endocrine care team to learn practical strategies for increasing vaccination rates for their patients with diabetes. Join endocrine experts Geetha Gopalakrishnan, MD, FACE and David C. Lieb, MD, FACE as they share their perspectives and experiences on advancing immunizations by using the CDC’s Standards for Adult Immunization Practice and working to build a practice culture of vaccine confidence. Visit www.AACE.com/immunization for additional education and resources.
Adrenal insufficiency is a life-threatening condition but diagnosis is typically delayed. The initial presentation is often non-specific and physician awareness must be improved to avoid adrenal crisis. Join endocrine experts Shobana Athimulam, MD, Clinical Assistant Professor, Division of Endocrinology, Bone and Mineral Disorders in Henry Ford Health, Detroit, Michigan, and Lucinda Gruber, MD, Assistant Professor, Division of Endocrinology, Diabetes, Metabolism and Nutrition at Mayo Clinic in Rochester, Minnesota, as they discuss the etiology and clinical presentation of patients with adrenal insufficiency, challenges in making the diagnosis, role of dynamic testing and management of special patient populations.
Nonalcoholic fatty liver disease (NAFLD) is a major public health problem that will only worsen in the future, as it is closely linked to the epidemics of obesity and type 2 diabetes mellitus. Given this link, endocrinologists and primary care physicians are in an ideal position to identify persons at risk to prevent the development of cirrhosis and comorbidities. Join endocrine expert Vin Tangpricha, M.D., Ph.D., as he interviews AACE Co-Chairs, guideline task force experts, Kenneth Cusi, MD, FACP, FACE, and Scott D. Isaacs, MD, FACP, FACE, about the newly released 2022 clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease, published in the May 2022 issue of Endocrine Practice (https://www.endocrinepractice.org/article/S1530-891X(22)00090-8/fulltext).
Having a high level of triglycerides in your blood can increase your risk of heart disease. Join endocrine experts Eliot A. Brinton, MD, FAHA, FNLA, FACE, President of Utah Lipid Center, and Past President, of the American Board of Clinical Lipidology, and Betul Hatipoglu MD, Professor of Medicine at CWRU School of Medicine, and Medical Director for Diabetes & Obesity Center at University Hospital Cleveland Medical Center, as they discuss clinical pearls about different lipid tests, and challenging cases of triglycerides such as pregnancy.
The landmark Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT®) was a global outcomes study designed to assess the cardioprotective efficacy and safety of VASCEPA® (icosapent ethyl) as an add-on to statin therapy in reducing major cardiovascular (CV) events in a high-risk patient population. Join endocrine experts Eliot A. Brinton, MD, FAHA, FNLA, FACE, President of Utah Lipid Center, and Past President, of the American Board of Clinical Lipidology, and Betul Hatipoglu MD, Professor of Medicine at CWRU School of Medicine, and Medical Director for Diabetes & Obesity Center at University Hospital Cleveland Medical Center, to learn about the results of the REDUCE-IT® trial and new developments in CV prevention.
Minimally invasive thyroid techniques are effective and safe when performed by experienced centers. While surgery and radioiodine treatment remain the conventional and established treatments for nodular goiters, new image-guided minimally invasive approaches appear safe and effective alternatives to treat symptomatic or enlarging thyroid masses. Join endocrine experts Vin Tangpricha, M.D., Ph.D., Professor of Medicine at Emory University School of Medicine, as he interviews Sina Jasim, MD, MPH, Associate Professor of Medicine at Washington University in St. Louis, about nonsurgical minimally invasive approaches to managing thyroid nodules/malignancy, as published in the April 2022 issue of Endocrine Practice (https://www.endocrinepractice.org/article/S1530-891X(22)00063-5/fulltext).
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