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Medtech Talk

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A weekly conversation with the innovators who will change how health care is delivered.
187 Episodes
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In this episode of Medtech Talk, host Geoff Pardo and Conor Hanley, PhD, CEO of FIRE1, discuss various topics ranging from leadership to entrepreneurship to raising funds. Hanely also talks about lessons learned about raising capital at BiancaMed, how he keeps investors on the same page, how he utilizes his board and partnerships, and how he assimilates other people’s perspectives while taking on a position. He also delves into his viewpoint on patient compliance, what attracted him to healthcare in the first place, and how Ireland transformed from an economic low point to the Celtic Tiger.  Medtech Talk boiler: The Medtech Talk Podcast explores the lives and stories of the people behind some of the greatest advancements in healthcare. Gilde Healthcare General Partner and podcast host, Geoff Pardo invites listeners to see themselves in the journeys of the greatest entrepreneurs, investors, and executives changing the landscape of medtech to save patients and innovate healthcare for future generations.      
In this month’s episode of Medtech Talk, host Geoff Pardo speaks with Rodney Perkins, M.D., serial medtech inventor and founder of several companies, including Collagen Corporation and Laserscope. Perkins delves into his extensive history as one of the industry’s most prolific and successful entrepreneurs whose inventions have helped shape many medical specialties. Perkins discusses what drew him to medicine and medtech, how to navigate the challenges of starting new companies, and why being aware of your own skillset is important to the growth of a company. He also offers advice on how to handle the stresses of entrepreneurship, including his own “entrepreneur’s survival kit” of self-care and understanding your limits. 
Starting a company is an intimidating feat. Starting multiple companies is even scarier. In this month’s episode of Medtech Talk, host Geoff Pardo speaks with Amr Salahieh, founder and CEO of Shifamed, about his extensive experiences of entrepreneurship in the medtech ecosystem. As the founder of several companies, including Sadra Medical, Maya Medical, and Apama Medical, Salahieh shares his tips and tactics on finding the right markets, taking care of your investors, and overcoming challenges when a company fails. He also offers his thoughts on the biggest obstacle in the medtech sector today and how Shifamed has remained sustainable compared to other organizations. Medtech Talk Links:  Cambridge Healthtech Institute   Medtech Talk  Gilde Healthcare   Shifamed Links: Shifamed  
Though the stigma around mental illnesses has lessened, there is an ongoing mental health crisis affecting the country—and the rest of the world. In this episode of Medtech Talk, host Geoff Pardo speaks with Nolan Williams, M.D. Associate Professor of Psychiatry and Behavioral Sciences at Stanford University, about how electrical signaling abnormalities in the brain could be behind mental illnesses and the different options used to treat these ailments. Dr. Williams also delves into how his background in psychology and neurology helped him better understand patients in crisis, how Magnus Medical’s methods differ from traditional transcranial magnetic stimulation therapy, and the difficult circumstance of the current state of hospitals and inpatient units. Medtech Talk Links:  Cambridge Healthtech Institute   Medtech Talk  Gilde Healthcare  Magnus Medical Links: Magnus Medical Stanford University Links: Stanford University School of Medicine Stanford University 
How does one decide to invest in the right company? In this episode of Medtech Talk, host Geoff Pardo speaks with Justin Klein, MD, JD, Co-Founder and Managing Partner at Vensana Capital, about how he uses his legal background to determine the best investment strategy, how he found his way into the medtech industry, and which areas of medicine fascinate him the most. He also talks about his experiences and lessons learned during his time as a partner at NEA, as well as his thoughts on what is working in the industry and what challenges obstruct it from its goals. 
How does one navigate the difficult road of entrepreneurship? How do you find the right industry for you? In this episode of Medtech Talk, host Geoff Pardo speaks with serial founder and med device CEO Keegan Harper, about overcoming the challenges of being your own boss and finding what you’re good at. Harper discusses what inspired him to become an entrepreneur, how he became interested and involved in medtech, and his experiences managing several start-up companies. He also details how he found his knack for choosing technology to invest in and develop, meeting the right people, figuring out the build-to-buy system, and his experiences at multiple companies, including Ablation Frontiers, TheraCardia, Bird Flex, and, now, Bolt Medical.   
Ceribell’s rapid seizure triage product for critical care received FDA’s Breakthrough Designation with an exclusive New Technology Add-on Payment (NTAP) from CMS. Everything about the ClarityPro product—from the innovative EEG headband to the EEG recorder and physician portal has been engineered to enable quick detection and response to non-convulsive seizure in a critical care or ED setting. In this episode of the Medtech Talk podcast, host Geoff Pardo speaks with Jane Chao, CEO of Ceribell, about the path to develop an innovative new product and her personal journey as well.Chao’s own story started with a love of numbers, a highly exclusive spot earned in a prestigious chemistry program in Beijing, a Ph.D. in biophysics, and roles at McKinsey, Novartis, and Genentech. For Ceribell’s genesis, Chao took lessons from all of those experiences—business knowledge gained at McKinsey, and a rich, interdisciplinary scientific background—to launch a new medtech business and engineer a new device to meet a critical, unmet medical need. Medtech Talk Links:  Cambridge Healthtech Institute   Medtech Talk Gilde Healthcare  
How has the bullishness of 2016-2022 impacted public markets and private companies? In this special episode of Medtech Talk, we share Geoff Pardo’s Medtech MVP 2023 panel, featuring Tak G Cheung, Partner at New Enterprise Associates; J.P. Peltier, Managing Director of Global Head, Healthcare Investment Banking at Piper Sandler; Michael Ryan, VP of Venture Capital & Business Development at Boston Scientific Corp; Gwen Watanabe, Managing Director at H.I.G. Capital; and Rob Winklemann, Managing Partner & CEO at Credo 180. The panelists discuss the implications for private companies, particularly those that were financed during the boom times, as well as strategies for keeping private companies financed, and the outlook for liquidity via M&A or IPO.  
Doug Godshall, President and CEO of Shockwave Medical, started off selling T-shirts as an engineering student. Today, he leads the most successful high-growth medtech company in the last twenty years. In this episode of Medtech Talk, host Geoff Pardo speaks with Godshall, who discusses his start in medical devices, experiences in a major medtech company, leadership and culture, and what it takes to succeed in the field. Godshall details the strategies behind sales such as understanding your customer’s full needs and why the quality and usefulness of your product is more important than the amount you sell.  He also shares his perspective on the type of company culture that creates a comfortable and collaborative environment that paves the way to success. Medtech Talk Links:  Cambridge Healthtech Institute   Medtech Talk  Gilde Healthcare  Shockwave Medical 
In his early education Anton Clifford was advised against focusing on both science and economics. But he’s put that education to good use in his entrepreneurial career. With a foundation in engineering, Clifford quickly turned to medical devices. First in his native Ireland and later in the US with Abbott Laboratories, Clifford got firsthand experience with device engineering as well as the challenges of launching new products, divisions, and companies.  On the journey to his current endeavor, Clifford had narrowed his focus to finding an engineering problem with a mechanical component: a massive unmet need with a surgical solution that was under-adopted. As he considered market opportunities, a friend and mentor, Josh Makower, directed him: You’re not trying to make something work; you’re trying to kill ideas.  The last idea standing, so to speak, was an implantable shock absorber, reducing load to the knee joint. After years of development, Moximed has released its FDA study on the most recent product—Misha—with “phenomenal outcomes.” Compared to a surgical alternative, Misha showed superior recovery, pain, function, and no mechanical failures.  Medtech Talk Links:  Cambridge Healthtech InstituteMedtech Talk  Gilde Healthcare  Moximed 
With a background as a trauma nurse and experience running clinical research programs, Stacey Pugh brought quite a bit of patient-focused experience with her when she shifted to industry. After several roles in the neurovascular space, now she’s leading the charge at Endogenix, which is using pulsed electric fields to treat Type 2 Diabetes. She and host, Geoff Pardo, talk about a medical officer’s first experience doing sales, the challenges in affecting change management in primary care, funding businesses with SPACs, and more.  Medtech Talk Links:  Cambridge Healthtech Institute   Medtech Talk  Gilde Healthcare  Endogenex 
Derek Herrera, founder and CEO of Bright Uro, grew up in a military family with a curious mind and a skill for building things. After graduating, he entered the Naval Academy, studied systems engineering and robotics, and became a Special Operations Marine Raider. When an injury left him paralyzed from the waist down, he launched a new career to improve the lives of spinal cord injury patients through medical innovation.   Herrera speaks with podcast host Geoff Pardo about his extensive military career and the leadership skills fostered during that time. He also talks about his first entrepreneurial pursuit creating a fully internal and remotely controlled device for chronic urinary retention, a common issue for spinal cord injury patients. Herrera discusses his new business, Bright Uro, which leverages advanced technology to create urological diagnostic devices. He says, “Not only will we offer a superior patient and customer user experience, a more comfortable technology, and improve clinical efficiency, we’re unlocking data that’s never been obtained before because there’s never been the capability to do so.” Links from this episode:  Gilde Healthcare Bright Uro UroDev Medical 
Growing up in Austria as the daughter of two physicians, Lisa Anderson, co-founder and CEO of Paragonix Technologies, spent many evenings around the dinner table discussing patient care with her parents. After pursuing advanced studies in biomedical sciences and medical genetics, Anderson ventured back into patient care and launched a donor organ preservation and transport company to dramatically improve the standard of care for many donor recipients.  In this episode, Anderson speaks with host Geoff Pardo about the current issues in organ transport and how their first device—the Paragonix SherpaPak Cardiac Transport System—significantly decreases the number of adverse events less than 24 hours after heart transplant surgery. She also talks about the company’s transition to a service-based business with the development of the Paragonix app, their expansion into transporting lungs, livers, and kidneys, and the strategies used to develop a straightforward and high-performing device. She says, “We wanted to provide a simple device that provides superior clinical outcomes, is easy to us, and has an intuitive user profile when [organ recoveries] occur. We provide [surgical teams] with superior organ preservation.” Links from this episode:  Gilde Healthcare Paragonix Technologies Paragonix SherpaPak Cardiac Transport System   
Fred Khosravi, chairman and CEO of Imperative Care, returns to the podcast for another engaging conversation with host Geoff Pardo about his personal and professional experiences in the medtech space. He speaks about the elements of preparedness that help entrepreneurs seize new opportunities, the importance of maintaining intellectual honesty in one’s work, and why a “market-first” mentality leads to industry success. He says, “It’s not a great medical innovation unless it ends up helping a lot of patients. Otherwise, it’s just a great invention.” Khosravi generously shares three decades worth of entrepreneurial wisdom and recounts stories of the people who profoundly impacted his career. He talks about viewing investors as partners not parents, the attributes that spur venture capitalists to invest in a CEO, the lessons learned from developing the number one intravascular filter in the global market, and his work at Imperative Care—a stand-alone comprehensive stroke and thrombectomy company. He also explains why he believes “freedom and innovation” set the American medtech industry apart and the path forward to make it even better.  Links from this episode:  Gilde Healthcare Imperative Care Incept Medical Incubator (Axtria, Ostial, Neurolutions, Instylla, Tulavi Therapeutics) 
This month host Geoff Pardo speaks with one of the most prolific entrepreneurs in the medtech industry, Fred Khosravi, chairman and CEO of Imperative Care, about the path that led him to start over 24 healthtech startups. Khosravi recounts leaving Iran at 17 and studying mechanical engineering at Tennessee Tech. He talks about his first experiences with medical device manufacturing and how he designed a fully automated process for making cataract lenses. Khosravi also shares his pioneering work in developing cardiac stents, how serendipity is really “opportunity meets preparedness,” and why every entrepreneur needs a board of directors. He clarifies, “Not your company’s board of directors, but your own personal board of directors: people who care about you to be skeptical about you and tell it to you like it is.” Links from this episode:  Gilde Healthcare Imperative Care  
As a trained neurosurgeon, Dr. Chris Mansi is familiar with the challenges patients face in accessing lifesaving treatments. After earning an MBA from Stanford and enrolling in their Biodesign Medical Innovation track, he learned to develop multifaceted and technology-based solutions to improve healthcare workflows.  In this episode, host Geoff Pardo speaks with Mansi about Viz.ai, a revolutionary application that increases patient access to life-saving treatments in over 1,200 hospitals. Every minute an ischemic stroke patient waits for treatment equates to approximately 2 million neurons lost and a week of disability. Viz.ai abbreviates the sometimes five-hour-long process of securing a specialist to merely minutes, changing the course of patients’ lives. Mansi also discusses how to address naivety in entrepreneurship, the value of an interdisciplinary mindset in improving patient outcomes, and the importance of creating a value-based company with mission-driven employees. Links from this episode:  Viz.ai 
Dr. Josh Makower is one of the few multidisciplinary leaders making a tremendous and broad-reaching impact on the medical device and consumer product industries. As an inventor, professor, CEO, and venture capitalist with experiences in medicine, bioengineering, business, and big pharma, Makower has led the charge in creating some of the most unique and practical designs.  In this episode, host Geoff Pardo speaks with Makower about his interests in science and technology at an early age, his college transition from music to engineering, and what he believes is the future of biodesign. Makower details the mechanics of his inventions for incontinence, chronic sinusitis, benign prostatic hyperplasia, and women’s health as part of the nine companies he created in the past 25 years. Finally, he speaks about the joy of teaching and offers sage advice to up-and-coming medtech innovators: “My classic piece of advice for anyone getting into any health-related field is you really have to be perseverant. You have to never give up because there are so many reasons to turn away and give up, but if you have a dream and believe in what you’re doing and are willing to listen and adapt, that’s key. I think anyone can win, and it’s just about believing in yourself and your vision.” Links from this episode:  Stanford University Stanford University School of Medicine ExploraMed, a medical device incubator Coravin Willow 
Before he began his Ph.D. program in biomedical engineering, Andy Doraiswamy bought a one-way ticket to Southeast Asia to explore and “find himself.” He was successful: discovering a love for mountain climbing’s physical and mental challenges and developing a practice of meditation that has proven helpful in both climbing and commerce. Since leaving academia, he’s been involved in startups at Advanced Vision Science, Oculeve, and now Koya Medical. Doraiswamy has a huge bias and love for eye care, he says, particularly intrigued by its complexity. He and host Geoff Pardo discuss how medical devices fare in academia, letting go of promising technology in an acquisition, and the shifts required when transitioning from COO to CEO. Links from this episode: Koya Medical 
Host Geoff Pardo talks with Adam Berman, CEO of Alleviant Medical, about the groundbreaking device treating heart failure without hardware or permanent implants. The Alleviant device mitigates shortness of breath in patients with diastolic heart failure by leaving behind a shunt cut from interatrial septum tissue. The shunt moves blood from the left atrium to the right, diminishing pressure on the lungs. Berman speaks about his start in biomedical engineering, gaining invaluable experience in the operating room, developing sales tactics and industry knowledge as a medical device field representative, and switching gears to create novel devices for cardiac care.  Links from this episode:  Alleviant Medical 
Geoff Pardo and three successful medtech CEOs who exited their companies through a different pathway— M&A, IPO, and SPAC—discuss the pros and cons of each. While market volatility is a given, Bruce Shook, Former President & CEO, Intact Vascular and Vesper Medical; Clint Carnell, Co-Founder & Chairman, OrangeTwist; Former CEO, BeautyHealth; and Leslie Trigg, CEO, Outset Medical agreed that successful CEOs keep their focus on delivering returns for their investors—whether private or public. If your company is solving a really important problem and is creating value for patients, you’ll ultimately succeed, Shook said. From there, Trigg pointed out, exit vehicles are simply different modes of transportation to the same place.  GUESTS:Bruce Shook, Former President & CEO, Intact Vascular and Vesper Medical Clint Carnell, Co-Founder & Chairman, OrangeTwist; Former CEO, BeautyHealth Leslie Trigg, CEO, Outset Medical, Inc. HOST:  Geoff Pardo, General Partner, Gilde Healthcare; Host, Medtech Talk podcast  LINKS:Cambridge Healthtech Institute Medtech Talk Gilde Healthcare OrangeTwist Outset Medical 
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