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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
1153 Episodes
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Professor Guerra begins an arc of lectures on the molecular events that describe the covalent modification and temporal variation of gene expression collectively called epigenetics.
T Lymphocyte communication with antigen presenting innate immune cells coupled with B cell activation may be regulated by a glycoprotein that links to discrete glycosylation patterns on membrane polypeptide domains
In this Authentic Biochemistry episode Dr Guerra unfolds the complex transcription factor and membrane & nuclear- receptor repertoire associated cytokine and chemokine axis activating and maintaining Treg cell differentiation to mediate the Th pro- inflammatory response
This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced and idiotypic age-associated disease in the CNS. 25 March 2019.
In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the bioenergetic and pro-inflammatory prodromal patho-biochemistry of age-onset Alzheimer's Disease using his diaeventontological toolkit.
Dr. Daniel J. Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.
Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current Alzheimer's Disease research
referencesGuerra, DJ.2026 Unpublished lecturesCell. 2021 Apr 1; 184(7)1790–1803.e17. Nature Cell Biology2022 volume 24, pages 940–953Balin, M. 1968 Volunteers Jefferson Airplanehttps://open.spotify.com/track/7pTL00cPeIGhvVNlq5qP0k?si=f5f42440ca1a4836Idris Davies,1958The Bells of Rhymney.Byrdshttps://open.spotify.com/track/1mpv6hIbfG75txI9zJGcf4?si=2e67db1d289d4b0aSloan. 1965. Eve of Destruction. Barry McQuirehttps://open.spotify.com/track/1Zi2ezNOqt9y9irC11xYpN?si=a291d387ff324313
ReferencesGuerra, DJ. 2026 Unpublished Lecture.Cell. 2021 Apr 1; 184(7):Cell. 2024. Volume 187, Issue 3 p733-749.e16February 01.Nat Immunol. 2018 Jul9;19(8):871–884. Vinson and Chatmon. 1930 Sitting on top of the World. Cream. Wheels of Fire lp.https://open.spotify.com/track/0aY5bJ4jRHiOd8eCMWmcy8?si=a969586b68694b0eLamb, R. 1972. Dialogues I&II Chicagohttps://open.spotify.com/track/02F55MPyLuAUnSSvDg4lP4?si=f9a8d6e6ff0c41e4Pankow,J.1969. Liberation. Chicago Transit Authorityhttps://open.spotify.com/track/385g7dy2YZ1uNV9AJhOpUv?si=b316eef0684e4682
ReferencesNat Immunol. 2018 Jul9;19(8):871–884. J Immunol Res. 2025 Jul17;2025:9328523Biochem Biophys Res Commun. 2024 Mar 12:700:149598.Int J Mol Sci. 2019 Oct; 20(19): 4962.Tempchin, G 1972 Peaceful Easy Feeling. Eagleshttps://music.youtube.com/watch?v=n-0lRkuNyj0&si=7cBHTtUT8_c2yC7xCorelli, A. 1700. Violin Sonata in D Minor. OP 5. No.7https://music.youtube.com/watch?v=uRv44TQTacA&si=fp8rT4JDtFRsD4ij
ReferencesCell. 2021 Apr 1; 184(7):1790–1803.e17Methods Mol Biol. 2022; 2497:129–140. Guerra, DJ.2026. Unpublished LecturesClapton/Bruce/Brown. 1967 Sunshine of your Love Live Cream Vol IIhttps://music.youtube.com/watch?v=tVCeZvusHCU&si=LzcFIKnxe0GP461mHenley/Browne, 1972, Take it Easy Eagleshttps://open.spotify.com/track/4yugZvBYaoREkJKtbG08Qr?si=915e639119db4c91Miller, R. 1962 King of the Roadhttps://open.spotify.com/track/3XG7bMVcMWLIn2k9jLAaAt?si=68578db0407f452f
ReferencesCurr Opin Allergy Clin Immunol 2025, 25:444–454Guerra. DJ.2026. Unpublished Lectures.BiolOpen. 2019 Oct 15; 8(10): bio040311Lennon/McCartney. 1966. Rain. Beatleshttps://open.spotify.com/track/48TNLcToLs8DWkdj5vYdiW?si=375c43203c1c4ccdClapton/Bramlett, 1970. Let it Rainhttps://open.spotify.com/track/7DiaNCPgH5dJ1cJ925jTAA?si=b8bfac43cdef493cPage/Plant. 1973. The Rain Songhttps://open.spotify.com/track/3JLrri1xSCui3bzITDJbkk?si=6c47b7b4a0974806 Townsend, P. 1973. Love, Reign O'er Me. The Whohttps://open.spotify.com/track/4Mqs0h95KAeNiGp7u4udlt?si=56521c6a1b71425aLightfoot, G. 1975. Rainy Day Peoplehttps://open.spotify.com/track/1TZteKaf5z3P3i87jyB8jc?si=def4f81ab3ef4100
ReferencesNature Immunology 2018. volume 19, pages871–884 Guerra, DJ. 2026 Unpublished Lectures ChemBioChem,2018. .: 19, Issue: 15, Pages: 1657-1663, Morrison/Manzarek/Krieger/Densmore. 1971. Riders on the Storm. Doors.https://open.spotify.com/track/14XWXWv5FoCbFzLksawpEe?si=ee8db94467dd4d0a
ReferencesMBOC 2011. Volume 22, Issue 18 3456–3464Guerra, DJ. 2026. Unpublished LecturesDiscoveries (Craiova). 2014 Sep 23;2(3):e29J Cell Mol Med. 2015 May 28;19(7):1427–1440J Cell Mol Med. 2015 May 28;19(7):1427–1440Signal Transduction and Targeted Therapy2025. volume 10, Article number: 254Dylan, B. 1964 Mr. Tambourine Manhttps://open.spotify.com/track/3RkQ3UwOyPqpIiIvGVewuU?si=7127b25041cf4972 Zevon, W. 2003. Keep Me in Your Heart for a Whilehttps://open.spotify.com/track/1fRlDQzrpvWd4BlIzifUkJ?si=0a8e5251592e49eaMozart, WA. 1773. Symphony 25 in G Minor K.183https://music.youtube.com/playlist?list=OLAK5uy_nYdGMRH0VYkIzQZQhIlX3utzG2dlDWurk&si=g3zc1O-3naltl3I7
ReferencesGuerra, DJ 2026. Unpublished LecturesBiol Open. 2019 Oct 15; 8(10): bio040311.Small GTPases. 2012 Jul 1;3(3):139–153.Cell Mol Biol Lett. 2024 Aug 10;29:108Front Immunol. 2019 May 31;10:1225Brain Commun. 2021 Mar 5;3(2):fcab020Balin M. 1967. Coming Back to Me Jefferson Airplanehttps://open.spotify.com/track/0TBntp6t4oS6UXjxikO5n7?si=ccff17969d2c4680Kokkonen, J. 1972. Water Song Hot Tuna https://open.spotify.com/track/5Qe0nAjBVDecK7SfZE9YUm?si=4c8689cc0a2e4a1ePaige, J 1974 Bron yr Aur Zeppelinhttps://open.spotify.com/track/5rgWj8h7lzbSmwpp0wFkXD?si=d08d8d2b18bc40dc
ReferenceseLife. 2022 Nov 25;11:e83073Lipids Health Dis. 2025 Jul1;24:225Cell Reports 2021 Volume 35, Issue 5109076May 04.Guerra, DJ. 2026 Unpublished LecturesMcGuinn/Parsons/White et al. 1968 Sweetheart of the Rodeo. The Byrdshttps://music.youtube.com/playlist?list=OLAK5uy_kejb97oJ9VJCssjIxpz2YeHK9htTy-wz0&si=kkIqFi6NfkhHCpl9
ReferencesGuerra. DJ 2026. Unpublished LecturesLipids Health Dis. 2025 Jul1;24:225Jagger/Richards. 1969 Paint it Blackhttps://open.spotify.com/track/63T7DJ1AFDD6Bn8VzG6JE8?si=7cb90ffb26b54512Beethoven LV. 1804 Symphony 3 in E Flat Major. Eroicahttps://music.youtube.com/watch?v=fhHcty9OM-0&si=ZWJt3uJUkjXY9ujt
ReferencesGuerra, DG. 2026. Unpublished LecturesLipids Health Dis. 2025 Jul 1;24:225Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Leadon/Frey/Henley/Meiser/Blue/Souther/Norman. 1973 Desperado Eagleshttps://music.youtube.com/playlist?list=OLAK5uy_k3UBMdBe0k-PWX6y1VCLJZVJogoUaKEco&si=KAdQVnU-qVFn_r52
ReferencesiScience 2024. 27, 109267, March 15, Front. Immunol., 2018,03 December Sec. T Cell Biologyv9Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Townsend, P 1973. Im One The Who Quadrophenia. https://music.youtube.com/watch?v=qvPVw0l5XpY&si=jHjslRqdHZH21KGHMozart, WA 1786. Piano Concerto in A Major. K 488.https://music.youtube.com/watch?v=V4S6UYv8-W4&si=AmbTM2OPzO10wJjx
ReferencesJ Biol Chem. 2011 Apr 8; 286(14): 11937–11950.Cardiovasc Diabetol.2020; 19: 33.J Cell Physiol. 2021 Apr;236(4):2333-2351Cytometry 2006. Part A 69 Issue 3Mar. Pages105-208Lennon/McCartney. 1964 Hard Day's Night. lphttps://music.youtube.com/playlist?list=OLAK5uy_kNANFuHzr_3bZH3S5aXxOT4X1ouKnjY4k&si=02aKQ86d5RTfyyY7CSNY, 1970. Deja Vu lp.https://music.youtube.com/playlist?list=OLAK5uy_neUnMuHswIr4wB5qPiV5iozF-550Cz3k8&si=neIOWnSei3lU7e07
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I engage with your episodes with considerable interest and a strong sense of curiosity. Discovering your lectures on Castbox was particularly gratifying. Thank you, Doctor.
listening to episode one from 2019 in which Doctor Guerra was talking about insulin and Alzheimer's disease. I googled it. now 12/12/2025 some are starting to call AD type 3 diabetes. BRAVO DR. DANIEL J. GUERRA!!!! . It seems to me that diabetes screws with everything in the body. . Robert Bristow LVN.