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Authentic Biochemistry
Authentic Biochemistry
Author: Dr Daniel J. Guerra
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
1099 Episodes
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Professor Guerra begins an arc of lectures on the molecular events that describe the covalent modification and temporal variation of gene expression collectively called epigenetics.
T Lymphocyte communication with antigen presenting innate immune cells coupled with B cell activation may be regulated by a glycoprotein that links to discrete glycosylation patterns on membrane polypeptide domains
In this Authentic Biochemistry episode Dr Guerra unfolds the complex transcription factor and membrane & nuclear- receptor repertoire associated cytokine and chemokine axis activating and maintaining Treg cell differentiation to mediate the Th pro- inflammatory response
This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced and idiotypic age-associated disease in the CNS. 25 March 2019.
In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the bioenergetic and pro-inflammatory prodromal patho-biochemistry of age-onset Alzheimer's Disease using his diaeventontological toolkit.
Dr. Daniel J. Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.
Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current Alzheimer's Disease research
ReferencesPlants (Basel). 2019 Sep 21;8(10):358J Biol Chem. 2018 Aug 3;293(38):14786–14797Proc Natl Acad Sci U S A. 2008 Oct 28;105(44):17199–17204Plant Physiol Biochem. 2014. Aug:81:121-7Weir/Anderson/Barlow. 1973.Weather Report Suite. Grateful Dead/Wake of the Floodhttps://music.youtube.com/watch?v=b9sY-kwa6RE&si=C4y54Qgf5oWMIq25Bruford/Squire/Anderson, 1972. Heart of the Sunrise Yes/Fragilehttps://music.youtube.com/watch?v=T5XWOOOCg-U&si=8mXJwUXB3M-bBqImBeethoven LV 1812. King Stephan Overture. OP. 117https://music.youtube.com/watch?v=dyHpvRVr0II&si=ab6mU0B6O-qS283u
ReferencesGuerra, DJ. 2026. Unpublished LecturesNature Plants 2017. volume 3, Article number:17041 Phys. Chem. Chem. Phys., 2020,22, 7912-7934 Hunter/Garcia. 1970. American Beauty. Grateful Deadhttps://music.youtube.com/playlist?list=OLAK5uy_nc3dHmM6xdsySO1SSxYLYzlm82rVZ1pfM&si=smpXUTpmTY2GEA_w
ReferencesGuerra, DJ 2026. Unpublished LecturesJBC 2022 Volume 298, Issue 12, December 102650 McBroom, A. 1979 The Rose. Conway Twittyhttps://music.youtube.com/watch?v=EWbS4Jg-rzY&si=sXQNNmgFOj8ymSmHHaydn, M. 1800. Cello Concerto in B flat Majorhttps://music.youtube.com/watch?v=Ku9ffFEpD1s&si=kqZoNcvEL10hgrRq
ReferencesJ Phys Chem B. 2022 Oct7;126(41):8214–8221.Biochemistry 2021, 60, 30, 2341–2348Methods Mol Biol. 2016; 1376: 175–194. Guerra, DJ. 2026. Unpublished LecturesSchubert, F. 1827. Winterreise D. 911https://open.spotify.com/album/7EtDwm4r9t4lYZJOow82Uf?si=cjiRRFJ0SW2VkU5jEUVegw
ReferencesGuerra, DJ.2026 Unpublished lecturesChopin F. 1834. Prelude in R Minor OP 28. No.4https://open.spotify.com/track/1Xf4sNtMKc1xiUhuIPAUg2?si=9a615b5c8fad4e67
References Guerra, DJ. 2026. Unpublished Lectures Opt Express 2025 Aug 25;33(17):36861-36875Plant Cell. 2013 Jul; 25(7): 2661–2678. J Biol Chem. 2018 Sep 21; 293(38):14786–14797. Plant/Paige/Jones. 1980. In the Light LZhttps://open.spotify.com/track/343ctUuXfw3vnE2eN7cURN?si=ad3ef3f1a79f4398Bruce/Brown/Clapton. 1967. Sunshine of Your Love. Cream Live Vol II.https://open.spotify.com/track/4KQilA0T8noRB4uwAQyiXz?si=c4357edac1bf45af
ReferencesCell. 2018 May 31;173(6):1356-1369.e22. Clinical and Molecular Teratology 2016. Volume 106, Issue 9 September Pages 749–760Biology (Basel). 2023 Mar 30;12(4):527. dInt J Mol Sci. 2021 Feb 22;22(4):2158. Anderson and Squire. 1971. I've Seen all Good People. Yes.https://music.youtube.com/watch?v=WfgPEh2J9aI&si=cTVabGFH5JYqN-EjMozart , WA. 1788. Symphony 40 in G Minor K550.https://music.youtube.com/watch?v=z_4jMxbwmVc&si=0n5dbpCqtE4WjYFw
ReferencesAdv. Drug Alcohol Res., 2025. 02 NovemberCell Mol Life Sci. 2022 Volume 5. May 13;79(6):292. Cell. 2018 May 31;173(6):1356-1369.e22. Addiction Biology 2025 Volume30, Issue2 February e70012Lamb,R. 1970. 25 or 6 to 4. Chicagohttps://open.spotify.com/track/5tORQL3XeeJnSUism6MOr9?si=6c9716ba92d643fePlant/Paige. 1973. Over the Hills and Far Away. LZ.https://open.spotify.com/track/2eDdFHgqNJltzlvlZFVDWd?si=505350f1228442aaLennon/McCartney. 1968. Dear Prudence. Beatles White Albumhttps://open.spotify.com/track/5NQYyej46WQkgCbnzGD21W?si=3758900e4a6c4151Joel. B. 1977. Scenes from My Italian Restaurant. The Stranger lphttps://open.spotify.com/track/3utq2FgD1pkmIoaWfjXWAU?si=fa4cb16abadf4b87
References Nature Neuroscience 2009.volume 12, pages 988–995 The Journal of Pharmacology and Experimental Therapeutics 2023. Volume 385, Supplement 3, June: 343 Alcohol Clin Exp Res. 2016 Sep 1;40(10):2030–2042. PNAS 2013. vol. 110 no. 45 November 5,Rom J Morphol Embryol .2021 Apr-Jun;62(2):553-561Alcohol, 2017-12-01, Volume 65, Pages 51-62Cells 2022, 11(11), 1773;Journal of Neuroscience 17 April 2024, 44 (16) e0918232024;Paige/Plant 1971. Stairway to Heavenhttps://open.spotify.com/track/5CQ30WqJwcep0pYcV4AMNc?si=2c35ff68c11e464fWinwood, S. 1968. Dear Mr. Fantasy Traffichttps://open.spotify.com/track/2pKGqD3UQBAdi0dCLNYR7a?si=dcfb9f099f9d40c0Seeger, P. 1965 Turn Turn Turn. Byrdshttps://open.spotify.com/track/5qBqBdfTEIWJwAS0Jm2F5R?si=ae25a0be1e474d96
ReferencesCells. 2019 Nov 12;8(11):1424Guerra, DJ. 2025. Unpublished LecturesAddict Biol. 2025 Feb 12;30(2):e70012.Howe, S. 1972. Mood for a Day Yes- Fragile lphttps://music.youtube.com/watch?v=1HqlC8XMeoI&si=2C-p6HOlr2rPytQnKrieger, R. 1968. Spanish Caravan. Doors.https://music.youtube.com/watch?v=6zrwCjjUqs0&si=OdWueLXUTn171u70Tchaikovsky, I. 1880.Capricio Italien OP 45.https://music.youtube.com/watch?v=L5TjETesZEg&si=_bgtrXyUHLV9L6GL
ReferencesPlatoPlotinusSt Augustine St BonaventureKant KierkegaardGuerra, DJ. 1955-Present Combined experiences and education (B.S., M.S., PhD.)Mozart, WA 1782-1785. The "Haydn Quartets I-VI completehttps://music.youtube.com/watch?v=dzzOzaWia90&si=FYF72Gd0GLvCaDMFBrown/Bruce 1966. I Feel Free. Cream.https://music.youtube.com/watch?v=prnbF8Eagdg&si=AUNjahyf56YCxFRo
ReferencesNutrients.2022 Nov 23;14(23):4978Cells.2019 Nov 12;8(11):1424Guerra DJ. 2025 Unpublished LecturesChristmas Musichttps://music.youtube.com/watch?v=DU9W7uOmBVY&si=dYEULJtoDWR-JcxD
ReferencesFront Cell Neurosci2017Feb1;11:14Biol Res.2023 Nov 17;56(1):61.Guerra, DJ 2025. Unpublished Lectures Staines B. 1985 The Miner's Songhttps://youtu.be/S_PRUCzZTp8?si=E4mE7aaQJx6yGka-McNeil, R.1988. Working Manhttps://youtu.be/H5QeTGcCeug?si=XACmep2PeVAXkm9VByrd/Moscowitz/Woodson/Agnello/Brotman/Marron/Forbes/Bogas/1Marinell/Grayson/Simon/Wood 1968. United States of America.https://music.youtube.com/playlist?list=OLAK5uy_luk8gEftP6An4svFOyDF3BAOm8n2oA_5c&si=4LdnZbvnN8C2njow


















I engage with your episodes with considerable interest and a strong sense of curiosity. Discovering your lectures on Castbox was particularly gratifying. Thank you, Doctor.
listening to episode one from 2019 in which Doctor Guerra was talking about insulin and Alzheimer's disease. I googled it. now 12/12/2025 some are starting to call AD type 3 diabetes. BRAVO DR. DANIEL J. GUERRA!!!! . It seems to me that diabetes screws with everything in the body. . Robert Bristow LVN.