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Psychedelic Therapy Frontiers

Psychedelic Therapy Frontiers
Author: Numinus Network
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© 2025 Psychedelic Therapy Frontiers
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The psychedelic renaissance is here! Join Dr. Steve Thayer, Dr. Reid Robison, and special guests as they explore the frontiers of psychedelic medicine and what it takes to cultivate a healthy mind, body, and spirit. Our hosts draw from their extensive knowledge and experience with psychedelic therapy research and treatment to discuss the science, practice, and art of psychedelic healing. If you are a helping professional, therapist, clinician, guide, healer, psychedelic enthusiast, or simply curious about mental, physical, and spiritual health, this is the podcast for you!
219 Episodes
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Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast we discuss a paper recently published in JAMA (Journal of the American Medical Association) entitled, “Single Treatment With MM120 (Lysergide) in Generalized Anxiety Disorder: A Randomized Clinical Trial.” This is a report on the results from Mind Medicine’s phase 2b clinical trial that Reid and I both had the pleasure of working on at Numinus Network’s clinical trial site, Cedar Clinical Research. We discuss what ...
Send us a text If you’ve ever listened to a therapist talk–whether in a therapy session, social media, or a podcast–you’ve likely heard them mention processing your emotions. But what does it actually mean to process your emotions? I’m being told I need to feel my feelings or process my trauma, but I don’t know how to do that. In today’s episode of the Psychedelic Therapy Frontiers podcast we’re going to explain what it means to process one’s emotions from a few different perspectives a...
Send us a text Sometimes it seems like life is crumbling around you. Maybe something terrible has happened or the accumulation of stressors is just too much to bear. What do you do when life keeps giving you lemons and you’re just sick of making lemonade? In today’s episode of the Psychedelic Therapy Frontiers podcast, we discuss tools and strategies for navigating life at its most difficult. For those of you who are new to the show, welcome! Psychedelic Therapy Frontiers is brought to ...
Send us a text Rapidly evolving artificial intelligence (AI) technologies has me both excited and terrified. On one hand, AI could contribute to exponential advancements in science, technology, engineering, and socioeconomics leading to human flourishing unlike anything we’ve ever seen. On the other, AI could derange human psychology, widen power gaps, disrupt society, and even evolve beyond human understanding or control. So what do we do about this? In today’s episode of the Psychedelic Th...
Send us a text Why does happiness feel so elusive for so many of us? Maybe you’ve had the experience where you long for a change, believing that once this change occurs then you’ll finally be happy. Then that change happens, but it didn’t deliver lasting happiness. You buy the new thing, take the vacation, achieve the goal, get the promotion and you feel happy for a while but eventually it feels like you’re back where you started. In today’s episode of the Psychedelic Therapy Fro...
Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast Dr. Steve Thayer and Dr. Reid Robison explore defense mechanisms. They discuss what defense mechanisms are, how they can be adaptive and/or maladaptive, the utility of understanding your defensive psychological patterns, the importance of a non-shaming interpretation of defense mechanisms, how to work with them in conventional and psychedelic-assisted therapy, and much more. *This episode originally aired 7/9...
Send us a text If you’re human you know what it’s like to be stressed. But what is stress exactly? Is all stress unhealthy or can our stress response help us adapt and build resilience? How does stress affect our mental and physical health? How can we effectively respond to and manage stress? In today’s episode of the Psychedelic Therapy Frontiers podcast, we discuss these questions and try to give you some useful tips for dealing with life’s inevitable stressors. For those of y...
Send us a text The path to FDA approved prescribable medicine has been a long and precarious one for psychedelics. However, recent reports by some of the major players in the psychedelic medicine space show promising results from clinical trials involving psilocybin and 5-MeO-DMT. In today’s episode of the Psychedelic Therapy Frontiers podcast, we review the topline data from these recent reports and explore what the future of psychedelic therapies might look like for people struggling ...
Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast, Dr. Steve Thayer and Dr. Reid Robison discuss attachment styles and how psychedelic therapy might be used to address issues related to attachment wounding. *This episode originally aired 5/16/23 Learn more about our podcast at https://numinusnetwork.com/learn/podcast/ Learn more about psychedelic therapy training opportunities at https://numinusnetwork.com/training/ Learn more about our clinical trials at ht...
Send us a text Could psilocybin help people with eating disorders process unconscious trauma? What’s the difference between the effects of psilocybin and SSRIs on depression? How does formulation and route of administration affect a LSD experience? What role does self-compassion play in the treatment of PTSD with MDMA-assisted therapy? In today’s episode of the Psychedelic Therapy Frontiers podcast, we explore recent research on these topics and more. For those of you who are new ...
Send us a text Ketamine has been in the news a lot lately and there are a lot of misconceptions about how this medicine is used for the treatment of mental health conditions. Is it safe and effective? Is it addictive? Is it a psychedelic? What’s the difference between ketamine and the FDA approved depression medicine, Spravato? In today’s episode of the Psychedelic Therapy Frontiers podcast, we discuss the history and clinical applications of these two medicines as we attempt to answer ...
Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast, we’re talking with Zen Master, Genpo Roshi. Roshi has been one of the pioneers of Zen throughout the U.S. and Europe. He’s known for his development of the Big Mind process, a method that combines Zen practice with Western psychological principles to facilitate personal transformation and insight. We discuss his early life experiences that set him on this path, the concepts of awakening and enlightenment, the natu...
Send us a text On this episode of the Psychedelic Therapy Frontiers podcast, Dr. Steve Thayer and Dr. Reid Robison discuss "bad trips". They talk about the difference between bad trips and challenging experiences; the factors during prep, facilitation, and integration that can prevent bad trips or turn them into useful challenging experiences; the prevalence of triggered psychosis and HPPD among psychedelic users; how to pick the right psychedelic therapist/guide/facilitator; and much more. &...
Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast, we’re talking with psychotherapist, Curt Kearney, about his new book, “Psychedelics and Internal Family Systems (IFS): A partnership in relational healing.” IFS is a powerful therapy model that’s becoming very popular these days. When we talk about which psychotherapy models might pair well with psychedelic tools, IFS is usually somewhere near the top of the list. In his book and in this conversation, Curt draws f...
Send us a text We’re back with part 2 of our 2-part series on what all effective psychotherapies have in common. Last week we introduced you to the common factors research on psychotherapy outcomes, using the work of Dr. Jeffery Smith, MD to help us structure the conversation. We discussed how entrenched maladaptive patterns, fueled by affective avoidance, contribute to mental health conditions and how all good psychotherapy models help people generate awareness around those patterns, make co...
Send us a text Have you ever looked for a new therapist and been overwhelmed by all the different kinds of therapy out there? Acronyms like CBT, ACT, EMDR, REBT, IFS, or confusing names like somatic experiencing or psychoanalysis–it can leave you wondering which one is best for the problems you’re experiencing. In today’s episode of the Psychedelic Therapy Frontiers podcast, we’ll try to reassure you a little bit by exploring what nearly all effective therapies have in common. This is a...
Send us a text What happens when you give scared rats ayahuasca? Can inhaled DMT treat depression? Does microdosing LSD help with ADHD? How do the insights occasioned by psychedelic experience affect therapeutic outcomes? Can cannabis use in adolescence increase the risk of developing schizophrenia? Does taking Paxil before LSD affect the psychedelic experience? In today’s episode of the Psychedelic Therapy Frontiers podcast, we dive into recent research exploring these questions and mo...
Send us a text Pain is an unavoidable feature of life. Some would argue that the desire to avoid or stop pain is a foundational driver of most human behaviors. But what about when pain is chronic? How much does our attitude toward our pain affect our experience of pain? Can psychedelic treatments offer new ways to treat chronic pain conditions? What can mindfulness practices offer to a person in pain? In today’s episode of the Psychedelic Therapy Frontiers podcast, we discuss these questions ...
Send us a text Meditation as a practice, a life path, or a mindset is central to many ancient wisdom traditions and modern psychotherapies. It’s also a useful tool for preparing for, navigating, and integrating psychedelic experiences. In today’s episode of the Psychedelic Therapy Frontiers podcast, we explore the definitions, components, and applications of meditation and mindfulness for psychedelic therapy and everyday life. For those of you who are new to the show, welcome! Psy...
Send us a text In today’s episode of the Psychedelic Therapy Frontiers podcast, we’re talking about a few counterintuitive ideas or paradoxes that one might encounter on their personal growth or healing journey. Due to their paradoxical nature, these ideas can be difficult to accept. Ideas like, “only when I accept myself as I am do I then have the freedom to change” can be confusing at first glance. Reid and I attempt to clarify a few of the most common and important paradoxes in today’s epi...