Discover
Heart Rate Variability Podcast
248 Episodes
Reverse
The 2024 Year in Review — Research That Shaped 2025
The Heart Rate Variability Podcast
In this special "Year in Review with a Twist," we shift our focus from the weekly news cycle to the big picture. We examine the most influential, highly cited research of 2024 to understand how these findings are revolutionizing clinical thinking and personal wellness in 2025.
HRV is no longer just a metric on a wearable; it has become the definitive framework for understanding resilience, adaptation, and human regulation.
Episode Highlights
The Anxiety Biomarker: Why 2024 research confirms HRV as a "top-down" signal of how the brain calms itself and its potential for identifying anxiety subtypes.
Combatting "Inflammaging": Exploring the link between vagal tone and chronic low-grade inflammation in aging populations.
The Autonomic Conditioning of Exercise: How physical activity trains the nervous system, not just the heart muscle.
Context is King: A deep dive into the 2024 "Sensitivity Review" highlighting how noise, heat, and even genetics must be accounted for in accurate readings.
Biofeedback Frontiers: From COPD and Spinal Cord Injury to classroom attention, we look at how HRV training is breaking new ground in rehabilitation and education.
Key Research Reviewed
Psychophysiology & Mental Health (2024): A landmark review synthesizing decades of data to establish HRV as a marker of prefrontal cortex regulation over the amygdala in anxiety disorders.
Gerontology & Immunology (2024): Research into "Inflammaging," positioning HRV as a non-invasive biomarker for biological age rather than just chronological age.
Sports Science & Performance (2024): A systematic review on HRV-guided training, emphasizing individual baselines over population norms for sustainable athletic performance.
Clinical Biofeedback Trials (2024): Notable studies involving COPD patients and those with chronic spinal cord injuries, proving the feasibility of HRV training even in complex physiological cases.
Neurodevelopmental Interventions (2024): Exploratory research into using HRV biofeedback for anxiety in Autism Spectrum Disorder and attention-building in school-aged children.
The 2025 Takeaway
"The question is no longer whether HRV is relevant, but how we apply it thoughtfully and responsibly. Autonomic flexibility is the foundation of emotional resilience, physical health, and cognitive performance."
Sponsor
This episode is brought to you by Optimal HRV. Bridge the gap between data and action with evidence-based tools designed for individuals, clinicians, and organizations. Explore our professional dashboards and HRV training e-gift cards today. Learn more at www.optimalhrv.com
Disclaimer: The information shared in this podcast is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before changing your health or wellness routines.
In this episode, Stephanie White joins Matt Bennet to explore the nature and uses of Very High Frequency Heart Rate Variability.
This Week in Heart Rate Variability: Air Pollution, Spiritual Wellbeing, Consciousness & Clinical Prediction
In this episode of The Heart Rate Variability Podcast – This Week in HRV, we expand the horizons of autonomic science. From the hidden impact of environmental pollutants to the neuro-spiritual connection of the "heart-brain axis," we examine how HRV serves as a vital bridge between our environment, our consciousness, and our clinical outcomes.
Episode Highlights
Environmental Stressors: New research into how air pollution and lead exposure synergistically drive autonomic dysfunction.
The Spirituality-HRV Link: Exploring Bayesian modeling of Heartbeat Evoked Potentials (HEP) as a biomarker for mental and spiritual wellbeing.
HRV as a Clinical Life-Line: A deep dive into a major meta-analysis confirming HRV’s power to predict mortality in heart failure patients.
Mapping Consciousness: How 24-hour HRV monitoring is helping clinicians differentiate between unresponsive wakefulness and recovery in patients with disorders of consciousness.
Precision and Reliability: Critical insights into the reliability of short-term HRV measurements across different body positions and environments.
Featured Studies & Resources
Environmental Research (2025) — Air Pollution & Chronic Lead Exposure: The synergistic impact of environmental toxins on cardiac autonomic function. Link to Study
Cogent Psychology (2025) — Bayesian Modeling of HEP and HRV: An exploratory study on using HRV and heart-brain communication as biomarkers for spiritual health. Link to ResearchGate
Scientific Reports (2025) — The Multidimensional Perspective of HRV: A comprehensive look at the brain-heart axis (BHA) and its role in predicting multi-system disease. Link to Nature
Cureus (2025) — HRV as a Predictor of Mortality in Heart Failure: A systematic review and meta-analysis on the prognostic value of HRV in cardiovascular care. Link to Cureus
Scientific Reports (2025) — Clinical Reliability of Short-Term HRV Insights into the consistency of HRV measurements in dual-environment and dual-position settings. Link to Nature
Acta Neurologica Belgica (2025) — HRV in Disorders of Consciousness Using 24-hour HRV metrics to identify emergence from minimally conscious states (PMID: 41389121). Link to PubMed
Psicothema (2025) — Autonomic Modulation & Psychological States Examining the latest protocols for integrating HRV into psychological and behavioral health assessments. Link to ScienceDirect
Key Takeaway
The "Heart-Brain Axis" is more than a concept—it is a measurable r...
This Week in Heart Rate Variability: Metabolic Syndrome, Nerve Blocks, EDS & Autonomic Health
In this episode of The Heart Rate Variability Podcast – This Week in HRV, we explore how the autonomic nervous system function connects metabolic disease, genetic disorders, targeted neural interventions, and the future of biofeedback science.
Episode Highlights
How Metabolic Syndrome drives chronic sympathetic overactivation and reduced HRV
Experimental evidence showing how the stellate ganglion block directly alters HRV and sympathetic tone
New data validating dysautonomia in Ehlers–Danlos Syndrome using HRV and autonomic testing
Why HRV is emerging as a critical clinical and research biomarker
A preview of the 2026 AAPB Annual Scientific Meeting and why it matters for clinicians and researchers
Featured Studies & Resources
Cureus (2025) — Autonomic Nervous System Dysregulation in Metabolic Syndrome https://www.cureus.com/articles/431819-autonomic-nervous-system-dysregulation-in-metabolic-syndrome-an-association-with-hypertension-and-cardiovascular-risk#!/
Autonomic Neuroscience (2025) — Selective Sympathetic Action on HRV After Stellate Ganglion Block https://www.sciencedirect.com/science/article/abs/pii/S1566070225001298
Cureus (2025) — Heart Rate Variability and Intrinsic Autonomic Coupling in Ehlers–Danlos Syndrome https://www.cureus.com/articles/429326-heart-rate-variability-and-intrinsic-autonomic-coupling-in-ehlers-danlos-syndrome?score_article=true#!/
Association for Applied Psychophysiology and Biofeedback (AAPB) About AAPB: https://aapb.org/about 2026 Annual Conference: https://aapb.starchapter.com/meetinginfo.php?id=43&ts=1763415344
Key Takeaway
Heart rate variability is a universal marker of resilience, translating metabolic stress, genetic vulnerability, and neural interventions into measurable physiological signals. HRV is no longer just a wellness metric—it's a clinical and scientific lens into autonomic health.
Sponsor
This episode is sponsored by Optimal HRV, providing evidence-based tools for measuring and training heart rate variability for individuals, clinicians, and organizations. Now offering e-gift cards for HRV training, app access, and professional dashboards. Learn more at www.optimalhrv.com
Episode 15 – This Week in Heart Rate Variability
Welcome to this week's exploration of the latest HRV science. In Episode 15, we discuss nine newly published studies that expand our understanding of HRV in mental health, physiology, chronic illness, and digital health innovation. This episode highlights remote biofeedback, pediatric heart dynamics, pregnancy and thyroid status, elite performance, cardiac rehabilitation, personalized training prediction, global research trends, autoimmune flare detection, and neurostimulation safety.
Featured Studies:
Remote HRV Biofeedback and Mental Health
“Efficacy and Methodology of Remote Heart Rate Variability Biofeedback Interventions for Mental Health: A Systematic Review and Meta-Analysis”
Vann-Adibe et al., Applied Psychophysiology and Biofeedback (2025)
https://link.springer.com/article/10.1007/s10484-025-09750-w
Pediatric HRV and Cardiac Complexity
“Age-dependent patterns of cardiac complexity unveiled by topological data analysis of pediatric heart rate variability”
Domínguez-Monterroza et al., PLOS ONE (2025)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337620
Subclinical Hypothyroidism in Pregnancy and HRV
“Comparative Evaluation of Thyroid Profiles and Heart Rate Variability in Newly Diagnosed Subclinical Hypothyroid and Euthyroid Pregnant Women”
Singh et al., Cureus (2025)
https://www.cureus.com/articles/427419-comparative-evaluation-of-thyroid-profiles-and-heart-rate-variability-in-newly-diagnosed-subclinical-hypothyroid-and-euthyroid-pregnant-women?score_article=true#!/
Performance Optimization in Firefighters
“Mental imagery and breathing exercises integrated into a standardized warm-up routine enhance sympathetic activation and optimize muscular performance in firefighters”
Biéchy et al., PLOS ONE (2025)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337431
Innovative Respiratory-Synchronized Pacemaker
University of Auckland research feature: “Pacemaker could help the heart heal”
Paton, Ben-Tal, Nogaret, and Stiles
https://www.auckland.ac.nz/en/news/2025/12/02/pacemaker-could-help-heart-heal.html
HRV and Personalized Fitness Modeling
“Advancing training effectiveness prediction in mass sport through longitudinal data: A mathematical model approach based on the Fitness-Fatigue Model”
Wang et al., PLOS ONE (2025)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337824
Global Trends in HRV Research
“A Two-Decade Bibliometric Analysis of Heart Rate Variability Research (2005–2024)”
Sharma et al., Psychiatry Research (2025)
In this episode, Matt Bennett talks with Dr. Richard Harris about his article: Single-case report: dynamic changes in cardiac function during shamanic journeying and Qigong meditation
Read the full article here: https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1608442/full
In this episode, we dive deep into the latest research from late 2025 and explore the exploding field of Psychophysiology. We look at how Heart Rate Variability (HRV) is becoming the "master key" for detecting everything from complex emotions to psychosis. We also break down a massive new study on how antidepressants shift your physical metabolism, the effectiveness of "light-guided" breathing for office stress, and how VR gaming affects your autonomic nervous system.
Links & Resources Mentioned:
Clinical Psychiatry & Pharmacology
Article: Which Antidepressants Shift Physiology? (Conexiant)
Takeaway: A look at how different antidepressant classes impact weight, blood pressure, and heart rate.
Paper: Reducing Artifact Preprocessing in HRV-Based Personalized Psychosis Prediction (World Scientific)
Takeaway: Using AI to predict psychosis directly from wearable data.
Breathing & Interventions
Paper: Light-guided resonant breathing enhances psychophysiological stress recovery in a simulated office environment (Nature Scientific Reports)
Paper: Resonant breathing in hospitalised psychiatric patients with persistent somatic symptoms (General Psychiatry / BMJ)
The Science of Stress & Emotion (HRV)
Paper: Measures of the psychophysiological response to recurrent anticipatory stress - the influence of neuroticism (Nature Scientific Reports)
Paper: Heart rate variability reveals graded task difficulty effects and sensitization dynamics (Springer / J. Physiol. Anthropol.)
Paper: HRV-Based Recognition of Complex Emotions: Feature Identification (MDPI Healthcare)
Physiology in Action (VR & Exercise)
Paper: Impact of Stereoscopic Technologies on Heart Rate Variability in Extreme VR Gaming Conditions (MDPI Technologies)
Paper: A controlled comparative study on the effect of arterial occlusion pressure on immediate sympathetic responses (Nature Scientific Reports)
This Week’s Studies:
Cardiac-vagal rhythm echoes on the heartbeat's mechanosensory imprint in the brain Candia-Rivera & Chavez — Communications Biology https://www.nature.com/articles/s42003-025-08969-x
Box breathing or six breaths per minute: Which strategy improves athletes' post-HIIT cardiovascular recovery? Kasap & Aydin — PLOS ONE https://doi.org/10.1371/journal.pone.0336615
The tolerance-related psychology and dynamic activity in the peripheral nervous system of Internet Gaming Disorder Chi & Hsiao — BioMedical Engineering Online https://biomedical-engineering-online.biomedcentral.com/articles/10.1186/s12938-025-01471-9
Heart rate variability biofeedback in adults with chronic spinal cord injury: a randomised feasibility study Schoffl et al. — BMC Neurology https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-025-04423-x
Video link: https://youtu.be/3vn_TF-ezTE
In this episode of The Heart Rate Variability Podcast, host Matt Bennett sits down once again with Stephanie White, HRV coach and educator known affectionately as “the HRV Guru.” Together, they dive deep into advanced heart rate variability concepts—especially heart rate fragmentation (HRF), very high frequency (VHF) activity, and new HRV metrics that can reveal hidden issues in autonomic health.
Stephanie shares insights from her work with clinicians, coaches, and patients—explaining why sometimes clients can’t reach the “Optimal Zone” in the Optimal HRV app and what physiological patterns might be behind it. She also outlines the importance of minerals, CO₂ balance, and careful data interpretation when working with HRV readings.
Key Topics Covered
Stephanie’s Background – Her recovery journey from chronic illness using HRV biofeedback and her work with VCU’s Comprehensive Autonomic Center.
Why HRV Data Sometimes “Doesn’t Make Sense” – How heart rate fragmentation can hijack HRV signals and confuse traditional measures like RMSSD.
RMSSD vs. SDNN – Why SDNN may better capture resonance frequency breathing and coherent sine wave patterns.
Understanding Heart Rate Fragmentation (HRF) – How alternating or sawtooth heart rhythms create misleading HRV statistics and mask underlying autonomic issues.
Introducing “Very High Frequency (VHF)” – What happens when HRF shifts heart power above 0.4 Hz, and why current HRV software often misses it.
The Role of CVNN and PSS – New or underused HRV metrics that can quantify fatigue, allostatic load, and fragmentation.
Practical Clinical Applications – How coaches and clinicians can identify HRF, interpret data accurately, and help clients avoid “false high” HRV readings.
Mineral Balance and HRV Health – Why calcium, sodium, potassium, and magnesium are crucial for healthy cardiac rhythm and recovery.
Building an HRV Coaching Certification Pathway – Stephanie’s vision for “HRV Behavioral Health Coaches” and measurable, data-driven client progress.
Studies & Resources Discussed
Insomnia and HRV in Medical Students Publication: Cureus Title: “Insomnia and Its Impact on Psychomotor Reactivity, Autonomic Function, and Psychological Well-Being Among Medical Students: A Cross-Sectional Analytical Study” Authors: Dhanusri, Rajalakshmi, Prakash, Bharadwaj, and Harichandrakumar Key Finding: The severity of insomnia among medical students was associated with slower reaction times and higher psychological distress, while short-term resting HRV remained largely unchanged. Early cognitive and mood changes appear before resting HRV declines, underscoring that subjective fatigue and attention lapses can be earlier indicators than RMSSD or SDNN. Link: https://www.cureus.com/articles/427559-insomnia-and-its-impact-on-psychomotor-reactivity-autonomic-function-and-psychological-well-being-among-medical-students-a-cross-sectional-analytical-study#!/
Meta-Analysis: HRV in Insomnia Disorder Publication: Sleep and Breathing Title: “Heart rate variability in patients with insomnia disorder: a systematic review and meta-analysis” Authors: Zhao and Jiang Key Finding: Across 17 studies and 921 participants, insomnia showed only mild, non-significant reductions in HRV measures such as SDNN and HF-norm. The review emphasizes methodological variability and suggests that chronic insomnia’s autonomic signature is subtle and context-dependent. Link: https://link.springer.com/article/10.1007/s11325-022-02720-0
Sleep Deprivation and HRV Publication: Frontiers in Neurology Title: “Effects of Sleep Deprivation on Heart Rate Variability: A Systematic Review and Meta-Analysis” Authors: Zhang, Niu, Ma, Wei, Zhang, and Du Key Finding: Eleven trials revealed consistent sympathetic dominance after sleep deprivation, as evidenced by decreased RMSSD, increased LF and LF/HF, and stable SDNN. These findings reinforce that RMSSD is the most sensitive marker of HRV for acute sleep loss and stress load. Link: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1556784/full
COMISA: Insomnia and Sleep Apnea Combined Publication: Scientific Reports Title: “Heart Rate Variability Analysis in Comorbid Insomnia and Sleep Apnea (COMISA)” Authors: Martín-Montero, Vaquerizo-Villar, García-Vicente, Gutiérrez-Tobal, Penzel, and Hornero Key Finding: Using over 5,000 overnight ECGs, COMISA patients showed reduced parasympathetic tone while awake and increased sympathetic drive during sleep. This dual imbalance likely explains elevated cardiovascular risk when both disorders coexist. Link: https://www.nature.com/articles/s41598-025-02541-7
Depression and HRV in Students Publication: Kompasiana Title: “Diagnosis of Depressio...
Studies & Resources Discussed
HRV Biofeedback for PTSD & Chronic Pain
Publication: Journal of Affective Disorders
Title: "Heart rate variability biofeedback improves co-occurring posttraumatic stress disorder and chronic pain symptoms: A randomised waitlist controlled trial"
Key Finding: This is the first RCT for this co-occurring population. Just six weeks of HRV biofeedback (HRVBF) led to a 24.3% decrease in PTSD symptoms and a 24.9% reduction in pain interference.
Biofeedback in Pediatric Care
Publication: Cleveland Clinic ConsultQD
Title: "Biofeedback Interventions With Psychotherapy in Pediatric Care: The Present and the Future"
Key Finding: A clinical guide and call to action for integrating biofeedback (like HRV) with psychotherapy to make self-regulation a concrete, measurable skill for children (e.g., pairing HRV biofeedback with exposure therapy for phobias).
Slow-Paced Contraction (SPC)
Publication: Biosourcesoftware.com
Title: "Add Slow-Paced Contraction to Your Practice"
Key Finding: This article details the "how-to" for Slow-Paced Contraction, a vital alternative to slow-paced breathing for patients with contraindications (like severe COPD, kidney disease, or metabolic acidosis).
Tai Chi & HRV
Publication: Medicine
Title: "Effects of a Tai Chi dance intervention on the autonomic nervous system in university students"
Key Finding: A 16-week Tai Chi intervention was shown to be an effective method to prevent excessive declines in resting HRV in university students, building autonomic resilience.
HRV & Non-Suicidal Self-Injury (NSSI)
Publication: Taylor & Francis Online
Title: "Association between heart rate variability and emotion dysregulation in adolescents with non-suicidal self-injury"
Key Finding: This review frames reduced HRV as a key physiological marker of the Emotion Dysregulation and autonomic imbalance that underlies the distress leading to NSSI in adolescents.
HRV in IPV Offenders
Publication: Journal of Criminal...
Find the article here: https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2839605
Episode Summary
In this insightful episode of The Heart Rate Variability Podcast, host Matt Bennett sits down with Dr. David Eddie, a clinical psychologist and researcher at Massachusetts General Hospital and Assistant Professor at Harvard Medical School. Together, they explore how Heart Rate Variability (HRV) is transforming the landscape of addiction recovery, psychotherapy, and digital mental health.
Dr. Eddie shares how HRV can serve as both a biomarker for relapse risk and a tool for emotional regulation, shedding light on how AI, wearable technology, and stress-detection algorithms could revolutionize real-time intervention in substance use treatment.
Listeners will gain a deeper understanding of how HRV biofeedback, digital monitoring, and personalized algorithms can support clients in recovery, enhance self-awareness, and inform clinicians’ decision-making in psychotherapy.
Key Topics Covered
How Dr. David Eddie began his HRV journey during graduate research at Rutgers and the Recovery Research Institute.
HRV as a biomarker for pathology and relapse risk in substance use disorder and mental health conditions.
Developing stress-detection algorithms that leverage real-time HRV data through wearables and AI.
Challenges of variability and individual differences in HRV data across populations.
Integrating ecological momentary assessment (EMA) and ambulatory psychophysiological monitoring for clinical insights.
How HRV biofeedback supports recovery and emotional regulation in psychotherapy and addiction treatment.
Ethical and practical issues around proprietary algorithms, data transparency, and commercial wearables.
The future of HRV research, AI integration, and passive monitoring in clinical psychology.
Key Takeaways
HRV is both a symptom and contributor to addiction and mental health challenges, offering potential for early detection of relapse risk.
Wearables and AI can help clinicians intervene in real time — possibly preventing relapse or emotional crises before they occur.
Personalized baselines and individual calibration are essential to improve algorithm accuracy for diverse populations.
HRV biofeedback provides an accessible, evidence-based method to help clients build resilience, reduce craving, and regulate their nervous system.
Future advances will make passive, scalable HRV monitoring a core element of digital mental health and recovery care.
About the Guest
Dr. David Eddie is a clinical psychologist and researcher at Massachusetts General Hospital’s Recovery Research Institute and the Center for Digital Mental Health, as well as an Assistant Professor of Psychiatry at Harvard Medical School. His work focuses on addiction recovery, psychophysiology, and integrating HRV into digital and clinical interventions.
Follow his work at Recovery Research Institute or through Harvard Medical School publications.
Show Notes
Resource 1:
Title: Associations between mental health disorder symptoms and cardiac function among Royal Canadian Mounted police cadets during the Cadet training program
Authors: R.N. Carleton, T.A. Teckchandani, J.P. Neary, J.E. Samayoa, J.M.B. Khoury, K.Q. Maguire, G.P. Krätzig, & G.J.G. Asmundson
Publication: Journal of Psychiatric Research
Link: https://www.sciencedirect.com/science/article/pii/S0022395625006521
Resource 2:
Title: Transgenerational effects of violence in adolescents exposed to grandmaternal intimate partner violence during pregnancy: Heart rate variability and DNA methylation
Authors: Nayara Cristina dos Santos Oliveira, Aline Furtado Bastos, Fernanda Serpeloni, & Simone Gonçalves de Assis
Publication: Behavioural Brain Research
Link: https://www.sciencedirect.com/science/article/abs/pii/S0166432825004735
Resource 3:
Title: The role of separation anxiety and autonomic dysregulation in pediatric vasovagal syncope. A cross-sectional study
Authors: Gaia Cuzzocrea, Andrea Fontana, Cristiana Alessia Guido, Marta Mascanzoni, Alberto Spalice, Camilla Guccione, Angelos Halaris, Stephen Porges, Lucia Sideli, & Vincenzo Caretti
Publication: Journal of Psychiatric Research
Link: https://www.sciencedirect.com/science/article/abs/pii/S0022395625006351
Resource 4:
Title: Acute cardiovascular and cerebral blood flow responses to high-frequency, low-amplitude vibration on the neck
Authors: Viet Q Dinh, Malinda Hansen, K Austin Davis, Lindsey Peralez, & Caroline A Rickards
Publication: Journal of Applied Physiology (via PMC)
Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC12551627/
Resource 5:
Title: Autonomic Flexibility and Early Treatment Success: Heart Rate Variability Predicts Remission in First-Episode Psychosis
Authors: Judith Rohde, Samantha Weber, Mateo de Bardeci, Aygün Ertuğrul, Grammato Amexi, Eva Schultz, & Sebastian Olbrich
Publication: Schizophrenia Bulletin
Link: https://academic.oup.com/schizophreniabulletin/advance-article/doi/10.1093/schbul/sbaf191/8305265?login=false
Resource 6:
Title: Interplay between ke...
Show Notes
Resource 1:
Title: Top 50 scariest movies of 2025 (and Fright Night Physiology)
Publication: WISN.com / Science of Scare Project
Link: https://www.wisn.com/article/top-50-scariest-movies-2025/69140286
Resource 2:
Title: Heart Rate Variability as a Key to Regulation and Stress
Author: D. N. Solomon
Publication: Psychology Today
Link: https://www.psychologytoday.com/us/blog/the-narrative-nurse-practitioner/202412/heart-rate-variability-as-a-key-to-regulation-and
Resource 3:
Title: Haunted House, Healthy Heart
Publication: Business Health Trust
Link: https://businesshealthtrust.com/news_insights/haunted-house-healthy-heart/
Resource 4:
Title: Why Do We Love Being Scared? The Science Behind Horror Movies
Author: A. Bennett
Publication: Promega Connections
Link: https://www.promegaconnections.com/the-science-behind-horror-movies/
Resource 5:
Title: Playing With Fear: A Field Study in Recreational Horror
Authors: M. M. Andersen, A. Coltan, et al.
Publication: PMC (via Emotion)
Link: httpss://pmc.ncbi.nlm.nih.gov/articles/PMC7734554/
Resource 6:
Title: Scared together: Heart rate synchrony and social closeness in a high-intensity horror setting
Authors: M. M. Andersen, et al.
Publication: PubMed (via Psychological Science)
Link: https://pubmed.ncbi.nlm.nih.gov/40720311/
Resource 7:
Title: I tracked my heart rate through the 10 haunted houses of Halloween Horror Nights...
Author: K. Weekman
Publication: Yahoo.com
Link: https://www.yahoo.com/entertainment/article/i-tr...
Show Notes
Resource 1:
Title: Pleasant odors specifically promote a soothing autonomic response and brain–body coupling through respiratory modulation
Authors: Valentin Ghibaudo, Matthias Turrel, Jules Granget, Maëlys Souilhol, Samuel Garcia, Jane Plailly & Nathalie Buonviso
Publication: Scientific Reports
Link: https://www.nature.com/articles/s41598-025-20422-x
Resource 2:
Title: Improved non-invasive detection of sleep stages when combining skin sympathetic nerve activity and heart rate variability analysis with AI
Authors: Md. Aktaruzzaman & Thomas H. Everett IV
Publication: Scientific Reports
Link: https://www.nature.com/articles/s41598-025-20282-5
Resource 3:
Title: Increased sleep apnea-specific hypoxic burden is independently associated with cardiovascular autonomic dysfunction in obstructive sleep apnea: A large-scale study
Authors: Chenyang Li, Zhenger Zhou, Xiaozhen Zhang, Enhui Zhou, Tianjiao Zhou, Jingyu Zhang, Xinyi Li, Jianyin Zou, Huajun Xu, Jian Guan, Yupu Liu, Suru Liu, Xiaoyue Zhu, Weijun Huang, Hongliang Yi, Shankai Yin
Publication: Sleep Medicine
Link: https://www.sciencedirect.com/science/article/abs/pii/S1389945725005386
Resource 4:
Title: Strengthening the heart by means of a gratitude intervention?
Authors: Andreas R. Schwerdtfeger, Claudia Traunmüller, Bernhard Weber & Christian Rominger
Publication: The Journal of Positive Psychology
Link: https://www.tandfonline.com/doi/full/10.1080/17439760.2025.2574048?af=R#abstract
Resource 5:
Title: Child and marital stress are associated with a psychophysiological index of self-regulatory capacities among parents of preschool children
Authors: Sasha MacNeil, Chelsea da Estrela, Warren Caldwell, Jean-Philippe Gouin
Publication: International Journal of Psychophysiology
Link: https://www.sciencedirect.com/science/article/pii/S0167876025007470?via%3Dihub
Resource 6:
Title: Factors influencing heart rate variability in nurses following night shifts: a prospective observational clinical study
Authors:
Resonance Frequency Breathing Explained
In this solo episode of the Heart Rate Variability Podcast, Matt Bennett explores the science and practicality of resonance frequency breathing, a term he notices is often misused. He introduces his AI counterpart, AI Matt, to present the research on resonance frequency breathing, which involves finding a natural rhythm for breathing that aligns with the body's optimal pace. Matt aims to delve into the correct usage of this term, discuss its scientific basis, and share practical applications in the episode.
Resonance Frequency Breathing Techniques
Matt discussed resonance frequency breathing, explaining that while 6 breaths per minute is often cited, the actual rate can vary based on factors like height. He noted that trained biofeedback practitioners have observed rates as low as 3.5 breaths per minute in special operators and professional athletes. Matt emphasized the importance of synchronization between the heart, breath, and nervous system, as well as the impact on brain functioning.
Resonance Frequency Breathing Assessment
Matt discussed the concept of resonance frequency breathing, noting that while research suggests an average of 6 breaths per minute, individual rates can vary widely. He explained that resonance frequency assessments involve gradually reducing breathing rate from 7 to 3.5 breaths per minute to find the rate that maximizes HRV. Matt emphasized that while height may influence resonance frequency, factors like fitness and body mass could also affect it, particularly for former athletes. He recommended practicing paced breathing before taking the assessment and suggested that repeated testing might show small changes in breathing rate over time.
Breathing Patterns and Resonance Frequency
Matt discussed the importance of regularly reassessing one's resonance frequency breathing to ensure accuracy, especially if consistent readings are obtained over several months without significant lifestyle changes. He shared his personal experience with adjusting his breathing patterns, including experimenting with a 4.5 to 3.5 breaths per minute rate and a 2:1 inhale-to-exhale ratio, inspired by recent research suggesting extended exhales can improve low-frequency heart rate variability. Matt emphasized the significance of personalized assessments using tools like the OptimalHRV app to determine optimal breathing patterns and encouraged others to explore different breathing techniques for maximum impact.
Residence Frequency Breathing Assessment
Matt discussed the importance of practicing residence frequency breathing assessment and emphasized the value of this technique in maximizing breathwork practices. He noted that while the concept is gaining recognition among fitness influencers and in peer-reviewed research, the full impact of the science is often overlooked in blog posts. Matt planned to include relevant research in the show notes and promised to cover this topic further in the next episode.
Show Notes
Resource 1:
Title: The relationship between heart rate variability and affective disorders: associations with symptomatic improvement and therapeutic alliance
Authors: Alexandra F. Gonçalves, Eugénia Ribeiro, Adriana Sampaio, Natividade S. Couto-Pereira, Pedro Moreira & Joana F. Coutinho
Publication: BMC Psychology
Link: https://bmcpsychology.biomedcentral.com/articles/10.1186/s40359-025-02960-1
Resource 2:
Title: Development and validation of the socio-evaluative N-back task to investigate the impact of acute social stress on working memory
Authors: Matthias Haucke, Sabrina Golde & Stephan Heinzel
Publication: Scientific Reports
Link: https://www.nature.com/articles/s41598-025-22611-0
Resource 3:
Title: Panic Attack Prediction for Patients With Panic Disorder via Machine Learning and Wearable Electrocardiography Monitoring: Model Development and Validation Study
Authors: Hayoung Oh, Hunmin Do, Chaehyun Maeng, Jinsuk Park, Taejun Yoon, Jihwan Kim, Hyeran Hwang, Seoin Choi, & Piao Huilin
Publication: Journal of Medical Internet Research
Link: https://www.jmir.org/2025/1/e69045
Resource 4:
Title: Non-invasive cardiovascular risk stratification in type 2 diabetes: a pulse wave and pulse rate variability analysis with machine learning
Authors: Saurav Kumar, Apakrita Tayade, Amber Shrivastava, & Ravi Bhallamudi
Publication: Biomedical Signal Processing and Control (via Science Direct)
Link: https://www.sciencedirect.com/science/article/abs/pii/S1746809425014491
Resource 5:
Title: How Tracking Your Health Metrics Can Help You Live Longer
Author: Alice Park (Interview with Zahi Fayad)
Publication: TIME
Link: https://time.com/7324741/health-metrics-tracking-live-longer/
Resource 6:
Title: Stressed at Work? Your Heart Disease Risk Just Jumped 50%. Here’s the One Number That Shows How to Fight Back
Author: Julien Raby
Publication: BoxLife Magazine
Link: https://boxlifemagazine.com/boost-heart-resilience-by-tracking-hrv/
Resource 7:
Title: “Resonance Breathing” Is The Anti-Stress Hack You Can Do Anywhere
Author: Carolyn Steber
Publication:...
Below are the links to the studies and articles discussed in this episode:
Personalized Respiratory Guidance for HRV: Lin, Z., Kong, W., Qiu, S., Luo, M., Wei, J., Guo, X., ... & Dan, G. (2025). High-precision personalized respiratory guidance model for enhanced breathing training: effects on heart rate variability. Biomedical Signal Processing and Control, 100, 108720.
https://www.sciencedirect.com/science/article/abs/pii/S1746809425012315
Therapy with Local Anesthetics and HRV: Weinschenk, S., Topbas-Selcuki, N. F., Benrath, J., Strowitzki, T., & Feisst, M. (2025). Effects of therapy with local anesthetics (TLA) on heart rate variability (HRV) over 24 hours. Chronobiology International.
https://www.tandfonline.com/doi/full/10.1080/07420528.2025.2560963?src=exp-la
Veterans, Service Dogs, and HRV: Krause-Parello, C. A., Friedmann, E., Taber, D., Zhu, H., Quintero, A., & Yount, R. (2025). Veterans Training Service Dogs for Other Veterans: An Animal-Assisted Intervention for Post-Traumatic Stress Disorder. Behavioral Sciences, 15(9), 1180.
https://www.mdpi.com/2076-328X/15/9/1180
Circadian Rhythm of HRV in Pregnancy: Rasouli, M., Feli, M., Azimi, I., Haghayegh, S., Sarhaddi, F., Niela-Vilen, H., ... & Rahmani, A. M. (2025). Circadian rhythm of heart rate and heart rate variability in pregnancy. npj Women's Health, 3(1), 57.
https://www.nature.com/articles/s44294-025-00107-6
Wearable Tech in Tennis Players: Wang, Z. (2025). Integration of wearable technologies in monitoring physical performance and psychological stress in tennis players. Acta Psychologica, 260, 105706.
https://www.sciencedirect.com/science/article/pii/S0001691825010194
Acoustic Features of Chants: Dolan, E. W. (2025, October 6). Chants across cultures share features that promote relaxation. PsyPost
In this episode of the Heart Rate Variability Podcast, host Matt Bennett sits down once again with Dr. Inna Khazan, a leading expert in HRV biofeedback and applied psychophysiology. Together, they unpack one of the most fascinating and misunderstood aspects of heart rate variability — low-frequency HRV — and its connection to self-regulation, stress resilience, and overall wellness.
Understanding Frequency Domains in HRV
Dr. Khazan begins by breaking down the concept of frequency domains in HRV. Just as white light contains multiple colors, the heart rate signal is composed of several distinct frequency components. Using tools like the Fast Fourier Transform, researchers can separate heart signals into high-frequency, low-frequency, and very-low-frequency ranges — each linked to specific physiological processes and parts of the autonomic nervous system.
Low Frequency HRV and the Baroreflex
The conversation dives deep into low-frequency power, which represents the interplay between the baroreflex (the body’s blood pressure regulation system) and the vagus nerve. Dr. Khazan explains how resonance-frequency breathing—typically practiced for 20 minutes a day—acts like strength training for these systems. Over time, this practice enhances emotional regulation, stress recovery, and overall heart-brain coherence.
Why Breathing Rate and Context Matter
Listeners learn that breathing too long in a low-frequency state can actually suppress other important HRV components, such as high-frequency and very-low-frequency power. Instead, Dr. Khazan recommends brief, consistent training sessions to balance all aspects of the nervous system. She also clarifies common misconceptions, including the outdated idea that low-frequency HRV measures sympathetic activity, emphasizing instead its parasympathetic and baroreflex origins.
Making Sense of HRV Metrics in Optimal HRV
Matt and Dr. Khazan discuss Optimal HRV’s “Optimal Zone” scale, which tracks the percentage of time users spend in low-frequency dominance during a session. They also unpack metrics like Max-Min and total low-frequency power, explaining how they interact and what each reveals about training efficiency and day-to-day readiness.
Practical Takeaways
Practice resonance-frequency breathing for 20 minutes a day to enhance self-regulation.
Avoid over-training in the low-frequency zone — balance is key.
Understand that low-frequency HRV is not a measure of stress or sympathetic activity, but rather a reflection of vagal and baroreflex strength.
Leverage your Optimal HRV app metrics to track progress, focus, and nervous-system adaptability.
Listen & Learn More
Explore more insights from Dr. Khazan and Matt Bennett on heart rate variability, stress regulation, and biofeedback science.
Visit OptimalHRV.com for resources, show notes, and upcoming episodes, including the "This Week in HRV" series, which highlights the latest HRV research and applications.
Welcome to the show notes for this week’s episode – This Week in HRV Edition. Below, you’ll find direct links to all the studies and articles discussed in this episode. These sources represent the latest research connecting HRV to mental health, resilience, environmental design, and leadership.
Research Studies:
Multisensory environmental effects on HRV and psychological restoration – Scientific Reports
Walking through green and grey: Exploring sequential exposure and multisensory environmental effects on psychological restoration – Building and Environment
The Impact of Vipassana Meditation on Health and Well-being: A Systematic Review of Current Evidence – Cureus
Cardiac timing effects on response speed are modulated by blood pressure, but not by heart rate variability, in healthy young adults – Physiological Reports
Heart-brain interaction in emotional regulation – Scientific Reports
Environmental stress and HRV in agricultural settings – Agricultural and Forest Meteorology
HRV and emotion regulation in depression risk – JAMA Psychiatry
HRV modulation through breathing and neural coherence – Frontiers in Human Neuroscience
News and Features:
Professor honored for pioneering heart–brain research – UC Irvine News
Solo practitioner uses HRV tech to improve patient care – Healthcare IT News
What is heart rate variability and how can it guide smarter leadership decisions – Manila Bulletin
HRV: The new secret weapon for heart resilience – Men’s Health
Each of these studies and stories offers a unique perspective on how HRV connects the hear...





