DiscoverFundamental Health with Paul Saladino, MD
Fundamental Health with Paul Saladino, MD
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Fundamental Health with Paul Saladino, MD

Author: Paul Saladino, MD

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Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.
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Animal-based diets, like a nose to tail carnivore diet, are about much more than food. They are a stepping stone to remembering where we have come from as humans.    Forgetting this history has led to myriad health and social ills today.   Check us out at www.Heartandsoil.co for the finest desiccated organ pills out there- get more nose to tail nutrition and thrive! Firestarter and Gut & Digestion are out now in addition to Beef Organs and Bone Marrow & Liver.    You can also always email me at drpaul@heartandsoil.co with questions!
Karen Martel is a Transformational Nutrition Coach who is a leading expert in ancestral nutrition, weight loss resistance and women’s hormone health. Host of the top-rated women’s health podcast The Other Side of Weight Loss and founder of the revolutionary program OnTrack, a membership community that has helped thousands of women to balance their hormones and lose weight. After struggling with her own health issues, Karen was determined to bring her knowledge to others with a bold new approach to women’s health and weight management. Karen's passion lies in helping women breakthrough weight loss resistance and find their personal weight loss code through hormone optimization. Karen is a health leader and researcher determined to revolutionize weight loss for modern women and men.     Time Stamps:   0:10:43 Podcast begins 0:12:56 Karen's story 0:22:06 Breaking down the menstrual cycle 0:35:50 Reasons for weight-gain 0:40:15 Heavy metal toxicity 0:52:36 Is environmental toxicity really the problem? 0:56:30 The onset of perimenopause 1:00:11 Effects of Macronutrient Distribution on Weight and Related Cardiometabolic Profile in Healthy Non-Obese Chinese: A 6-month, Randomized Controlled-Feeding Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672080/ 1:04:39 The progesterone steal and the importance of LDL 1:12:05 Low carb diets  1:16:18 Low carb is no panacea 1:19:17 Addressing the root cause of metabolic dysfunction 1:23:44 Carbohydrate and workout timing for women 1:27:33 How to structure a diet as a woman 1:32:07 Where zero carb goes all wrong 1:37:41 Where to find Karen Martel 1:38:27 Karen's radical hot springs adventure       Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoil.co, @heartandsoilsupplements on Instagram  Belcampo: www.belcampo.com Use the code “carnivoremd” for 20% off your order!  Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io,    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order! Force of Nature Regenerative meats: Forceofnature.com
Do the Hadza really consume 100g of fiber per day? Do we really know what a healthy gut microbiome is? Doubt it! When asked to rank their preferences for food (their diets are essentially meat, honey, berries, baobab fruit, and tubers) they consistently rank honey as their favorite and tubers last! In this video, I break down a number of articles looking at how the Hadza eat, their predilection for honey and meat, their oral health, and the seasonal cycling of their microbiota. I challenge the notion that we know what a "healthy" gut microbiome really is and suggest that this is better defined by clinical outcomes rather than myopic interpretations of individual species/phyla. I also share my own gut results on a nose to tail carnivore diet with honey in it.   Check us out at Heart & Soil (www.heartandsoil.co) if you need more nose to tail nutrition in your life! Firestarter (our high stearic acid tallow from suet) and Gut & Digestion are out now.     You can also follow us at @heartandsoilsupplements on IG.  
Brad Marshall is the author of the Blog Fire In A Bottle and the creator of The Croissant Diet.  Mildly obsessed with food and its history, his work focuses on trying to place current ideas about diet, including keto and carnivore diets into the framework of traditional Dietary patterns.     Brad has a genetics degree from Cornell, a certificate from The French Culinary Institute, has studied cancer at Memorial Sloan-Kettering Cancer center and worked as a programmer for the Berkeley Drosophila Genome Project.  He spent the last 15 years raising rotationally grazed pastured pork on his farm in upstate New York while running a butcher shop, local food restaurant and USDA inspected meat processing facility.   Brad is also the founder of Firebrand Meats, which is dedicated to producing pork and poultry products that are low in Linoleic acid, the n6 polyunsaturated fat (PUFA) whose intake has seen a dramatic worldwide increase in the last century.     https://reddit.com/r/SaturatedFat    Time Stamps: 0:13:55 Podcast Begins 0:15:14 Emmy's story https://fireinabottle.net/emmys-story/ 0:15:16 Change your fat, change your life 0:20:55 Disastrous Trends In American Bacon    https://fireinabottle.net/polyunsaturated-fat-pufa-in-pork-and-chicken/ 0:23:55 The problem with pork and chicken in the US 0:30:12 Brad's fascinating background 0:36:19 The croissant diet 0:45:27 Stearic acid vs linoleic acid 0:47:32 Plateaus on a ketogenic diet 0:53:54 Linoleic acid is the likely culprit 0:55:25 The shortcomings of the ketogenic understanding   0:58:58 The feasting mimicking diet 1:04:46 ROS is Satiation https://fireinabottle.net/ros-is-satiation/ 1:08:18 How linoleic acid affects blood glucose and satiety 1:12:21 All about insulin receptors 1:16:22 Fatty acids and ROS formation 1:28:29 Metformin 1:36:38 Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress https://www.sciencedirect.com/science/article/pii/S1550413107002562#bib64 1:41:40 Antioxidants prevent health-promoting effects of physical exercise in humans https://www.pnas.org/content/106/21/8665#:~:text=Notably%2C%20by%20blocking%20exercise%2Ddependent,vitamin%20C%20and%20vitamin%20E. 1:41:53 Stop megadosing Vitamin C 1:46:34 Butter Causes a High Level of Available Energy 8 Hours After a Meal https://fireinabottle.net/butter-causes-a-high-level-of-available-energy-8-hours-after-a-meal/ 1:58:28 A diet enriched in stearic acid protects against the progression of type 2 diabetes in leptin receptor deficient mice (db/db) https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1002&context=physiology_etds 1:59:56 Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice https://www.researchgate.net/publication/265650090_Dietary_Stearic_Acid_Leads_to_a_Reduction_of_Visceral_Adipose_Tissue_in_Athymic_Nude_Mice 2:01:29 The Body Fat of Obese Adults is Highly Unsaturated https://fireinabottle.net/the-body-fat-of-obese-adults-is-highly-unsaturated/ 2:05:31 Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578804/ 2:12:22 Stearoyl-CoA Desaturase-1 Is Associated with Insulin Resistance in Morbidly Obese Subjects https://link.springer.com/content/pdf/10.2119/molmed.2010.00078.pdf 2:17:14 The Pima paradox 2:19:48 Classification of Obesity with Respect to Morbidity https://journals.sagepub.com/doi/abs/10.3181/00379727-200-43417?journalCode=ebma 2:20:56 Brad' radical karaoke tribute 2:21:52 Where to find Brad Marshall Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand and are developing a US based supply chain. Check us out at: www.heartandsoil.co, @heartandsoilsupplements on Instagram    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order! Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd
Stearic acid is an 18 carbon saturated fat that has intriguing effects on the human body. It's been shown to positively affect mitochondrial activity, and diets that are low in cause mitochondria to change activity and phenotype in negative ways. Mouse models of this fatty acid also suggest some profoundly powerful effects on glucose tolerance and visceral fat when compared to oleic acid (18C monounsaturated fat), and linoleic acid (18C polyunsaturated fat). I break it all down in this video and share my RBC fatty acid levels as well as a compelling n=1 case study of Emmy's weight loss with dietary shifts away toward more stearic acid and less linoleic acid.    Check us out at Heart & Soil (www.heartandsoil.co) if you need more nose to tail nutrition in your life! Firestarter (our high stearic acid tallow from suet) and Gut & Digestion release this week!    You can also follow us at @heartandsoilsupplements on IG.   Controversial thoughts: How to get Omega-3 without Rancid Fish Oil and why Linoleic acid makes you Fat.  With levels of linoleic acid consistent with our evolutionary past, omega-3s aren't an issue if you are eating nose to tail! I also talk about CLA, how linoleic acid makes you fat. Check us out at www.heartandsoil.co  and @heartandsoilsupplements on instagram to get nose to tail nutrition!
Benjamin Bikman earned his PhD in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore studying metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the origins and consequences of metabolic disorders, including obesity and diabetes, with a particular emphasis on the role of insulin. He frequently publishes his research in peer-reviewed journals and presents at international science and public meetings.   Time Stamps   0:11:14 Podcast Begins 0:11:54 Ben's Background 0:17:53 The root of chronic disease 0:25:38 All about insulin 0:31:14 Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification https://www.semanticscholar.org/paper/Regulation-of-free-fatty-acid-metabolism-by-insulin-Campbell-Carlson/9be324b8af9ced5a8b7e1902257e3fb9308b4db1 0:31:51 Insulin stops lipolisis 0:34:35 Insulin's affect on the liver 0:40:10 Insulin and muscle cells 0:43:20 Why you want to increase protein as you age 0:48:47 Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204/#:~:text=Low%20Protein%20Intake%20is%20Associated,Younger%20but%20Not%20Older%20Population&text=Cell%20Metab.,Author%20manuscript. 0:51:00 Animal-based diets optimize muscle protein sythesis 0:55:12 Industrial Seed oils have a fantastic publicist 0:58:05 Do carbs drive metabolic dysfunction? 1:07:07 Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man https://link.springer.com/article/10.1007/BF00400466 1:07:42 How linoleic acid drives metabolic dysfunction 1:09:32 How linoleic acid drives metabolic dysfunction.  1:11:47 Low serum insulin in traditional Pacific Islanders--the Kitava Study https://www.metabolismjournal.com/article/S0026-0495(99)90258-5/pdf 1:14:29 Carbs are not to blame 1:19:05 Thriving is dependent on micronutrients 1:22:19 The secret to overcoming plateaus on low carb diets 1:25:28 Epidemiological studies in a total highland population, Tukisenta, New Guinea: Cardiovascular disease and relevant clinical, electrocardiographic, radiological and biochemical findings https://www.sciencedirect.com/science/article/abs/pii/0021968173900313 1:25:58 Classification of Obesity with Respect to Morbidity https://journals.sagepub.com/doi/abs/10.3181/00379727-200-43417?journalCode=ebma 1:27:46 Does fructose make us fat? 1:28:32 What makes honey different? 1:30:45 Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095052/#:~:text=Within%20the%20limitations%20of%20the,in%20patients%20undergoing%20orthodontic%20treatment. 1:31:11 Substituting Honey for Refined Carbohydrates Protects Rats from Hypertriglyceridemic and Prooxidative Effects of Fructose https://academic.oup.com/jn/article/132/11/3379/4687329 1:32:15 Effect of fructose on body weight in controlled feeding trials https://www.ncbi.nlm.nih.gov/books/NBK84702/ 1:33:21 Oral health in transition: the Hadza foragers of Tanzania https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172197 1:34:53 Hyperplastic vs hypertrophic fat cell growth 1:40:01 FADH2, NADH, and mitochondrial magic 1:43:27 Diet fat composition alters membrane phospholipid composition, insulin binding, and glucose metabolism in adipocytes from control and diabetic animals https://www.jbc.org/content/265/19/11143 1:43:27 Unwanted insulin sensitivity 1:50:01 Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice https://www.researchgate.net/publication/265650090_Dietary_Stearic_Acid_Leads_to_a_Reduction_of_Visceral_Adipose_Tissue_in_Athymic_Nude_Mice 1:52:16 dietary stearic acid regulates mitochondria in vivo in humans https://www.nature.com/articles/s41467-018-05614-6 1:54:17 Effects of Macronutrient Distribution on Weight and Related Cardiometabolic Profile in Healthy Non-Obese Chinese: A 6-month, Randomized Controlled-Feeding Trial https://pubmed.ncbi.nlm.nih.gov/28655596/ 2:01:29 CarnivoreMD's CGM readings 2:05:16 CarnivoreMD's Fatty Acid Markers 2:06:28 Where to find Ben Bikman 2:09:19 What Ben Bikman finds radical       Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com, @heartandsoilsupplements on Instagram    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd  Force of Nature Regenerative meats: Forceofnature.com
With levels of linoleic acid consistent with our evolutionary past, omega-3s aren't an issue if you are eating nose to tail! I also talk about CLA, how linoleic acid makes you fat. Check us out at www.heartandsoil.co  and @heartandsoilsupplements on instagram to get nose to tail nutrition!
Elle Russ  returns for her second show! She is a bestselling author, TV/Film writer, and seasoned life coach. She is the author of Confident As Fu*k and The Paleo Thyroid Solution – a book which has helped thousands of people around the world reclaim their health. Elle is also the show host for NYT’s bestselling author Mark Sisson’s popular Primal Blueprint Podcast.  Time Stamps:  0:10:44 Beginning of Podcast with Elle Russ 0:12:14 Elle's Story 0:13:50 The outdated "expertise" of thyroid doctors 0:16:17 Understanding the thyroid & reverse T3 https://sproutshealth.com/the-role-of-reverse-t3-in-thyroid-function-part-1/#:~:text=Reverse%20T3%20is%20like%20a,still%20may%20experience%20hypothyroid%20symptoms. 0:24:44 Hypothyroidism Chart https://www.straighthealthcare.com/hypothyroidism.html 0:27:26 Chemistry of Thyroid Hormones http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/thyroid/chem.html 0:29:16 Thyroid Hormone Synthesis http://pathwaymedicine.org/thyroid-hormone-synthesis 0:30:30 Proper testing for Hashimoto's thyroiditis 0:31:03 Leveraging Carnivore for Hashimoto's 0:31:52 Why test for Reverse T3? 0:34:40 Get a comprehensive thyroid panel 0:37:06 Iron's role in thyroid hormone function 0:39:29 The interconnectedness of organ systems 0:41:56 Treating the whole body 0:43:16 Eat your spleen! 0:45:34 Everything works together 0:48:52 Should we sweat high iron levels? 0:50:29 Improve your orgasm quality 0:51:40 Optimizing sex hormones 0:53:04 Calorie restriction tanks thyroid and metabolic health 0:53:44 Calories in calories out fails 0:55:06 The deionase-selenium relationship 0:57:29 Organ meats are superior sources of minerals 1:00:59 T3 / rT3-Ratio is Associated with Insulin Resistance Independent of TSH https://tahomaclinic.com/Private/Articles1/Thyroid-rT3/Ruhla%202011%20-%20T3-rT3-ratio%20is%20associated%20with%20insulin%20resistance%20independent%20of%20TSH.pdf 1:01:17 Thyroid function must be interpreted in the context of metabolic status 1:01:52 Insulin resistance reexamined 1:03:17 Thyroid dysfunction and metabolic syndrome are mutually causal 1:06:30 Moving away from the symptom-treatment paradigm 1:07:32 The immense value of functional medicine practitioners 1:10:37 How thyroid health effects your lipids 1:12:49 Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041250/ 1:14:04 Holistically curing restless leg syndrome 1:15:52 Veganism makes no sense 1:20:17 MTHFR, B Vitamins and organ meats http://atlasgeneticsoncology.org/Genes/GC_MTHFR.html 1:20:26 Why we need organ meats 1:23:52 Expertly dosing thyroid hormone 1:38:54 CarnivoreMD's thyroid labs 1:41:59 Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892312/ 1:42:52 Various Possible Toxicants Involved in Thyroid Dysfunction: A Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740614/ 1:44:36 Elle Russ' free thyroid guide and book 1:45:22 Elle Russ keeps it radical on secret hiking trails   Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com, @heartandsoilsupplements on Instagram    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd   
Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    Controversial thoughts! Two solid studies which show the dangers of linoleic acid!  
Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Lucy’s Bio: Lucy Mailing, PhD received her Bachelor’s in Biology from Kalamazoo College and her PhD in Nutritional Sciences from the University of Illinois, where her dissertation research focused on the effects of diet and exercise on the gut microbiome in states of health and disease. Lucy has authored several peer-reviewed journal articles related to the microbiome and health and was named an Emerging Leader in Nutritional Sciences by the American Society for Nutrition in 2017. Lucy has also served as staff research associate for the Kresser Institute for Functional and Evolutionary Medicine since 2015. Lucy is the founder and sole author of NextGen Medicine, a site dedicated to evidence-based articles about the microbiome, gut and skin health, and nutrition. She is regularly invited to speak on gut health around the country and has been recognized as one of the most trusted experts in the integrative health space. Lucy plans to continue her academic training and begin a postdoc in 2020 after a gap year dedicated to NextGen Medicine.   Time Stamps:   0:12:07  Podcast starts   0:12:41  Lucy Mailing's story   0:14:13  How exercise affects the microbiome   0:15:34  Lucy breaks down the microbiome   0:25:15  Mapping your biodiversity   0:28:56  Alpha diversity vs Beta diversity   0:31:08  Medication's effect on biodiversity   0:32:38  Seasonal diets improve biodiversity   0:37:21. Fiber! Do we need it?   0:43:53  Diet rapidly and reproducibly alters the human gut microbiome   0:46:02  How Lucy healed her eczema   0:50:01  Selecting the least toxic plant foods   0:52:19  Akkermansia   0:55:19  What makes a healthy microbiome?   0:58:43  The root causes of small intestinal dysbiosis   1:02:59  Bacteria-lectin interactions in phytohemagglutinin-induced bacterial overgrowth of the small intestine  https://pubmed.ncbi.nlm.nih.gov/3208205/   1:02:59  Inflammation's link to proteobacteria overgrowth   1:04:24  A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131798/   1:05:27  Will low fiber diets degrade the gut's mucosal layer?   1:06:33  Fermentation of animal components in strict carnivores: A comparative study with cheetah fecal inoculum  https://academic.oup.com/jas/article-abstract/90/8/2540/4702338?redirectedFrom=fulltext   1:08:01  Microbial flexibility on a carnivore diet   1:11:10  How to fix a broken gut   1:26:32  Stress, community, and gut health   1:28:37  Where to find Lucy Mailing   1:29:39  Lucy's radical scuba dive   Heart & Soil: www.heartandsoilsupplements.com  @heartandsoilsupplements on Instagram   Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd  JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  
Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Time Stamps:   0:12:03 Michael Ruscio's Background 0:14:38 Divergence from dogmatism 0:19:55 Start with the gut 0:24:28 Food reactivity latency 0:26:28 Healing the gut: the algorithmic approach 0:30:11 Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435786/ 0:30:14 Elimination protocols 0:33:31 The healing power of fiber-free diets 0:44:05 How to feed your microbiota 0:46:59 Diet rapidly and reproducibly alters the human gut microbiome https://www.nature.com/articles/nature12820 0:47:41 Non-fiber solutions for the microbiome 0:52:35 Targeting long-term gut health through a 360 approach 0:56:22 Is the Carnivore diet sustainable for long-term adherence? 0:58:33 The spectrum of plant food toxicity 1:02:19 Leveraging the power of probiotics 1:19:12 Michael Ruscio's radical body sliding Heart & Soil: www.heartandsoilsupplements.com  @heartandsoilsupplements on Instagram   Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Lets Get Checked: 20% off your order at www.TRYLGC.com/carnivoremd  JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  
Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!  Heart & Soil: www.heartandsoilsupplements.com
Heart & Soil is now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com    The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!  Dr. Vincent M. Pedre, Medical Director of Pedre Integrative Health and President of Dr. Pedre Wellness, is a Board-Certified Internist in private practice in New York City since 2004. His philosophy and practices are a blend of both Western and Eastern medical traditions. He is a Clinical Instructor in Medicine at the Mount Sinai School of Medicine, as well as certified in yoga and Medical Acupuncture. Time Stamps:   0:10:46 Dr. Vincent Pedre’s background  0:13:17 The vastness of our microbiomes  0:18:31The effect of GMOs on the microbiome of the soil 0:23:15 Reversing climate change through healing the soil 0:28:41 Healing the microbiome through reconnecting with nature.  0:33:41 Saving the planet through creating ecosystems  0:34:32 Observations of the gut microbiome of the Hadza 0:39:24 Fiber does not increase microbiome diversity  0:40:44 Diet rapidly and reproducibly alters the human gut microbiome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957428/ 0:43:35 Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets https://academic.oup.com/ajcn/article/71/3/682/4729121 0:45:23 The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy https://www.nature.com/articles/s41522-018-0073-2?fbclid=IwAR1q7BKu4IN1-9g1E7PGBpwfvzVPu7Xe2g4omFEMR7B8HfBMKrd2kIHMCVw 0:45:50 Reduced Mass and Diversity of the Colonic Microbiome in Patients with Multiple Sclerosis and Their Improvement with Ketogenic Diet https://www.frontiersin.org/articles/10.3389/fmicb.2017.01141/full 0:47:36 How to build gut bacteria diversity  0:52:09 No fiber? No butyrate? No problem 0:57:48 The metabolic inefficiency of plant nutrition 1:03:30 Genetics and varying tolerances  1:06:59 Metabolic flexibility  1:13:55 The circadian rhythm of the gut microbiome  1:16:39 Seasonality and the microbiome  1:17:58 What wrecks your biodiversity  1:24:37 Where to find Dr. Vincent Pedre       Heart & Soil: www.heartandsoilsupplements.com    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order! JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order!    Heart & Soil is also now a reality! This is my passion company founded to help a few million more people reclaim their ancestral birthright to radical health through nose to tail nutrition. We are making grass fed, grass finished desiccated organ capsules from regenerative farms in New Zealand. Check us out at: www.heartandsoilsupplements.com  In this AMA episode I answer questions from Ben Greenfield about my book, The Carnivore Code. It’s a deep dive into much of the science of an animal-based way eating. Prepare to learn a ton! Time Stamps:   8:03 Carnivore diet background, framework   18:25 Is there a magic ratio of fat to protein we should aim for? What is rabbit starvation?   25:53 A Review of Issues of Dietary Protein Intake in Humans https://pdfs.semanticscholar.org/4f00/4c6ff9159de2753b060df2ea1aab936db9ec.pdf   33:01. Is the decline in height and health fully attributable to plant agriculture or could it be due to industrialization?   38:43 Why do present day hunter-gatherers have no access to wild game?   42:54 How do we know that our high stomach acidity was driven by the consumption of animals?    45:09 The Evolution of Stomach Acidity and Its Relevance to the Human Microbiome https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134116   50:51 How do herbivores detoxify plant toxins?   56:34 Coevolution of poisonous plants and large herbivores on rangelands  https://journals.uair.arizona.edu/index.php/jrm/article/view/6858/6468   1:02:09 What are the studies of isothiocyanates in humans?   1:04:39  Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892312/   1:07:03  Why molecular hormesis is bad news   1:14:42  Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060837/    1:18:03 Green tea extract only affects markers of oxidative status postprandially: Lasting antioxidant effect of flavonoid-free diet   https://www.researchgate.net/publication/11310865_Green_tea_extract_only_affects_markers_of_oxidative_status_postprandially_Lasting_antioxidant_effect_of_flavonoid-free_diet   1:20:08 Uric acid and glutathione levels during short-term whole body cold exposure https://pubmed.ncbi.nlm.nih.gov/8063192/   1:21:14 Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans https://www.nature.com/articles/ncomms14337   1:22:58  Is there an acceptable dose of isoflavones?    1:23:53  Goitrogenic and Estrogenic Activity of Soy Isoflavones https://www.jstor.org/stable/3455387?seq=1   1:25:32 Isoflavones: estrogenic activity, biological effect and bioavailability  https://www.researchgate.net/publication/233538635_Isoflavones_Estrogenic_activity_biological_effect_and_bioavailability   1:26:48 Low Dietary Soy Isoflavonoids Increase Hippocampal Spine Synapse Density in Ovariectomized Rats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330193/   1:29:56 Is resveratrol really something we should avoid?   1:31:09  David Sinclair’s work on Resveratrol https://www.ncbi.nlm.nih.gov/pmc/?term=sinclair%2C+david+resveratrol   1:32:02 Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4‐month randomised trial in middle‐aged men https://pubmed.ncbi.nlm.nih.gov/25939591/#:~:text=Conclusion%3A%20In%20this%20population%20of,PSA%2C%20testosterone%2C%20free%20testosterone%2C   1:33:03 Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease https://pubmed.ncbi.nlm.nih.gov/26784973/   1:33:53 Prooxidant activity of research all in the presence of copper ions: mutagenicity in plasmid DNA https://www.sciencedirect.com/science/article/abs/pii/S0378427405001190?via%3Dihub   1:35:17 Resveratrol levels and all cause mortality in older community-dwelling adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346286/   1:36:16  resveratrol improves vascular function and mitochondrial number but not in glucose metabolism in older adults  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861959/   1:37:29  What are event-related potentials and how are they measured?   1:37:29 Food processing and emotion regulation in vegetarians and omnivores: an event-related potential investigation  https://www.sciencedirect.com/science/article/abs/pii/S0195666319300595?via%3Dihub   1:40:54 What really drives insulin resistance?   1:48:37  Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164353/   1:51:02 dietary stearic acid regulates mitochondria in vivo in humans  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081440/   1:53:52  What would you change in your diet if you had cancer?    1:56:03 Halted Progression of Soft Palate Cancer in a Patient Treated with the Paleolithic Ketogenic Diet Alone: A 20-months Follow-up http://pubs.sciepub.com/ajmcr/4/8/8/   1:57:29 Complete Cessation of Recurrent Cervical Intraepithelial Neoplasia (CIN) by the Paleolithic Ketogenic Diet: A Case Report https://www.researchgate.net/publication/322291809_Complete_Cessation_of_Recurrent_Cervical_Intraepithelial_Neoplasia_CIN_by_the_Paleolithic_Ketogenic_Diet_A_Case_Report   1:58:47  Are there any studies looking at telomere length in plant vs animal food diets?    2:00:10 Processed meat, but not unprocessed red meat, is inversely associated with leukocyte telomere length in the Strongheart family study  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037876/   2:00:41 Epigenetic clock analysis of diet, exercise, education, and lifestyle factors https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361673/   2:00:54  Effects of diet on telomere length: systematic review and meta-analysishttps://www.karger.com/?DOI=10.1159/000486586   2:02:00  Dietary intervention modifies DNA methylation age assessed by epigenetic clock  https://doi.org/10.1002/mnfr.201800092   2:04:21  Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/137.2.363    2:07:40 Would eating fruit without the seeds be a healthy choice?    2:08:07  Why does CarnivoreMD prefer unrendered fat?   2:00:37  Is dietary saturated fat something to be concerned about?  Heart & Soil: www.heartandsoilsupplements.com    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order! JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
Heart & Soil is now LIVE! I couldn't be more excited to share the message of nose to tail nutrition and help more people include organs in their diet. Check us out at www.heartandsoilsupplements.com!    The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Founder and CEO of Perfect Keto & Equip Foods, host of The Natural State Podcast, author of the best-selling Keto Answers. Former sports rehab clinician turned entrepreneur, trained in functional medicine and ordered labs and set treatment plans for hundreds of patients.   Time Stamps:   3:52  Being in touch with your environment bolsters human health 9:29 Why regenerative agriculture is the only way forward 16:00 On a mission to get people eating real food 17:00 Using business to force [positive] change upon the system 18:50 The importance of respecting complex systems 20:35 Chronic disease is a genetic and environmental mismatch  21:23 Returning animals to their natural environment 23:34 Lab-grown meat, and other carbon giants 28:00 Nature’s carbon cycle unnatural carbon introduction 31:31 Seasonality and diversity diminishes toxic load 40:00 Genetic adaptation takes thousands of generations 48:10 The value of learning the survivalist lifestyle 55:13 The best use of social media 1:00:20 How Anthony Gustin stays centered 1:04:30 Where to find Anthony Gustin   Heart & Soil: www.heartandsoilsupplements.com    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Belcampo: Use the Code CarnivoreMD for 20% off!    JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com  
The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Tommy Wood MD, PhD is an elite-level professional nerd who has coached world class athletes in a dozen sports.  He has an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo. Tommy is a Research Assistant Professor at the University of Washington, a Research Scientist at the Institute for Human and Machine cognition, and is on the scientific advisory board of Hintsa Performance. He is also CSO (Chief Snake Officer) at the Costa Rican Center for Bro Research. Tommy lives in Seattle with his wife Elizabeth and their two goofy boxers. In his spare time he can usually be found cooking, reading, or lifting something heavy.   Time Stamps:   10:15 Tommy on Coronavirus. 13:00 Why it's okay to be wrong as a scientist. 15:00 Where are we now with Coronavirus? (12:24) (14:20-14:59)   22:17 Boris Johnson Moves To Ban Junk Food Discount Deals To Fight Obesity https://www.independent.co.uk/news/uk/politics/boris-johnson-junk-food-ban-buy-one-get-one-free-obesity-coronavirus-a9611766.html   24:45. Tommy’s article on metabolic health and pandemics.Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness https://onlinelibrary.wiley.com/doi/full/10.1002/lim2.2   27:45  COVID-19 severity is predicted by earlier evidence of accelerated aging https://www.medrxiv.org/content/10.1101/2020.07.10.20147777v1   37:10 Is there an ideologically ‘’perfect’’ diet.   40:25 How does metabolic health affect our immune system? (38:44)   FIGURE 41:47  An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-2994-z   42:55 The NLRP3 inflammasome: Role in metabolic disorders and regulation by metabolic pathways https://pubmed.ncbi.nlm.nih.gov/29339210/ 45:15   Analysis and modulation of the TH1/TH2 cytokine balance https://www.imd-berlin.de/en/subject-information/diagnostics-information/th1th2-cytokine-balance.html   46:57  Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357061/   56:10. Are ethnic populations at greater risk?     59:10  Impact of obesity and metabolic syndrome on immunity https://academic.oup.com/advances/article/7/1/66/4524061   60:15. Insulin Resistance.    1:14:50 What causes pathologic insulin resistance?   1:19:07 Polyunsaturated fatty acids (1:19:30)    1:19:29  Increase of Adipose tissue little lake acid in US adults in the last half centuryhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642429/   1:32:29   Tissue levels of polyunsaturated fatty acids during early human development https://pubmed.ncbi.nlm.nih.gov/1532827/   1:31:52  Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic dietshttps://pubmed.ncbi.nlm.nih.gov/15070924/   1:35:52   Dietary a little lake acid elevates endogenous 2-AG anandamide and induces obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/   1:37:10 Saturated fatty acids (studies) (1:50:20)   1:37:33  Effects of step-wise increase in dietary carbohydrate on circulating saturated fatty acids and palmitoleic acid in adults with metabolic syndrome https://pubmed.ncbi.nlm.nih.gov/25415333/   1:46:14. Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice https://pubmed.ncbi.nlm.nih.gov/25222131/   1:47:53 Elevated serum C-reactive protein and free fatty acids among non-diabetic carriers of missense mutations in the gene encoding lamin A/C (LMNA) with partial lipodystrophy.  https://pubmed.ncbi.nlm.nih.gov/12524233/ 1:52:31  Muscle and nerve pathology in Dunnigan family partial lipodystrophy https://n.neurology.org/content/68/9/677.figures-only   1:54:06  Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systemic review and meta-analysis of randomized controlled trialshttps://pubmed.ncbi.nlm.nih.gov/20351774/ 1:49:45  Effects of 4-hydroxnonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease.  https://www.sciencedirect.com/science/article/pii/S2213231713000396   2:00:04  Incorporation of 13-hydrooxyoctadecadienoic acid (13-HODE) into epidermal ceramides and phospholipids: phospholipids C-catalyzed release of novel 13 HODE-containing diacylglycerol https://pubmed.ncbi.nlm.nih.gov/8169529/   2:04:45.  Fructose.   2:06:21  Fructose in perspective https://www.researchgate.net/publication/244479961_Fructose_in_perspective   2:11:33  Metabolic effects of fructose and worldwide increase in obesity https://journals.physiology.org/doi/full/10.1152/physrev.00019.2009   2:13:06  The effects of fructose intake on serum uric acid vary among controlled dietary trials https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327749/#:~:text=Hypercaloric%20supplementation%20of%20control%20diets,with%20no%20evidence%20of%20heterogeneity.   2:14:32  Effect of fructose on body weight in controlled feeding trials https://www.acpjournals.org/doi/full/10.7326/0003-4819-156-4-201202210-00007   2:15:16  Effect of fructose on blood pressure. A systematic review and met analysis of controlled feeding trials. https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.111.182311   2:06:44  Challenging the fructose hypothesis: new perspectives on fructose consumption and metabolism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649105/   2:20:35  Substituting honey for refined carbohydrates protects rats from hypertriglyceridemic and pro oxidative effects of fructose.   https://academic.oup.com/jn/article/132/11/3379/4687329   2:26:40 Tomy’s experience on a nose to tail carnivore diet.   2:32:10 Where to find Tommy online/the most radical thing he has done recently. Heart & Soil: www.heartandsoilsupplements.com    Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Belcampo: Use the Code CarnivoreMD for 20% off!    JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com  
The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Tommy Wood MD, PhD is an elite-level professional nerd who has coached world class athletes in a dozen sports.  He has an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo. Tommy is a Research Assistant Professor at the University of Washington, a Research Scientist at the Institute for Human and Machine cognition, and is on the scientific advisory board of Hintsa Performance. He is also CSO (Chief Snake Officer) at the Costa Rican Center for Bro Research. Tommy lives in Seattle with his wife Elizabeth and their two goofy boxers. In his spare time he can usually be found cooking, reading, or lifting something heavy.   Time Stamps: 8:07 Start of Podcast 8:52 The mechanism of caffeine/other compounds found in coffee/tea/chocolate in the human body. 11:27 Paul’s thoughts on coffee.  15:42 Tommy’s thoughts on coffee. 21:37 Human detoxification of plant toxins.  24:22 Regional differences in genetics. 26:00 Benefits of  Elimination diet. 27:37 Tommy’s issues with low carb diets. 29:52 Is insulin anabolic?  36:07 Protein requirements  37:17 Physiologic insulin resistance.  51:47 What Causes insulin resistance?  58:12 Digestion of processed fat and carbohydrate  59:47 What is the fastest way to fix insulin resistance? 1:01:47 How the processing of food changes your physiology.  1:04:22 Insulin resistance in asian populations. 1:06:32 The bagel study. 1:08:37 Low-carb-high fat vs. low fat-high carb.  1:12:07 Electrolyte balance on low carb diet.  1:17:47 Where to find Tommy online? 1:19:57 The most radical thing Tommy has done recently. References:  https://www.researchgate.net/publication/235366395_Addition_of_Carbohydrate_or_Alanine_to_an_Essential_Amino_Acid_Mixture_Does_Not_Enhance_Human_Skeletal_Muscle_Protein_Anabolism Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Belcampo: Use the Code CarnivoreMD for 20% off!    JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Dr. Cordain is a Professor in the Department of Health and Exercise Science at Colorado State University in Fort Collins, Colorado. His research emphasis over the past 15 years has focused upon the evolutionary and anthropological basis for diet, health and well being in modern humans.Currently, Dr. Cordain's research team is exploring the connection between dietary elements that increase intestinal permeability (primarily saponins and lectins) and autoimmune disease, particularly multiple sclerosis. He has lectured extensively on the "Paleolithic Nutrition" concept world wide, and has written three popular books (The Paleo Diet, John Wiley & Sons; The Paleo Diet for Athletes, Rodale Press; The Dietary Cure for Acne) summarizing his research findings. Time Stamps:    10:16 Start of the podcast. 18:46 Paul’s nutrition journey  19:26 Do plant foods trigger inflammation? 24:16 Plants don't want to be eaten. 29:51 WGA  32:07 Lectins. 35:56 Lectins and autoimmunity  37:26 Genetic susceptibility to plant toxins.  43:01 Nuts and Seeds. 46:06 Diet of hunter gatherers.  1:00:16 Did our Paleolithic ancestors  live short lives? 1:02:22 Fructose consumption.  1:13:06 Thoughts on a carnivore diet. 1:23:16 Is there risk of nutrient deficiencies on a Carnivore Diet?  1:29:46 Sodium to Potassium ratio. 1:40:16 Do animals seek out salt? 1:51:06 Trevor’s fasting insulin levels.  1:56:16 Are there carnivore diet studies in the medical literature? 1:58:26 Are there nutrient deficiencies on a carnivore diet? (continued)  2:01:06 Other plant toxins.  2:03:30 Optimizing a carnivore diet. 2:11:16 Where to find Dr.Cordain, Mark, and \trevor’s work online. 2:12:06 The most radical thing they have done recently. References: https://onlinelibrary.wiley.com/doi/abs/10.1002/evan.20266 https://pubmed.ncbi.nlm.nih.gov/23493539/#:~:text=Indeed%2C%20the%20only%20distinction%20is,%22alcohol%20without%20the%20buzz.%22 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731857/#:~:text=For%20instance%2C%20the%20studies%20which,increase%20insulin%20resistance%20%5B2%5D. https://pubmed.ncbi.nlm.nih.gov/29507217/#:~:text=Here%20we%20show%20that%20high,insulin%20resistance%2C%20and%20fatty%20liver. https://pubmed.ncbi.nlm.nih.gov/29359681/#:~:text=%3A%2010.1017%2FS0007114517002926.-,Involvement%20of%20NLRP3%20inflammasome%20in%20the%20impacts%20of%20sodium%20and,insulin%20resistance%20in%20normotensive%20Asians.&text=Salt%2C%20promoting%20oxidative%20stress%2C%20contributes,oxidative%20stress%2C%20improves%20insulin%20sensitivity. https://pubmed.ncbi.nlm.nih.gov/1132118/ https://optimisingnutrition.com/optimising-paul-saladino-mds-nose-to-tail-carnivore-diet/ Low Salt Intake and Insulin Sensitivity: https://www.ncbi.nlm.nih.gov/pubmed/10371376 https://www.ncbi.nlm.nih.gov/pubmed/10371376 https://www.ncbi.nlm.nih.gov/pubmed/?term=iwaoka+glucose+salt https://www.ncbi.nlm.nih.gov/pubmed/7997846 https://www.ncbi.nlm.nih.gov/pubmed/3050268 https://www.ncbi.nlm.nih.gov/pubmed/8487006  https://www.ncbi.nlm.nih.gov/pubmed/21036373 https://www.ncbi.nlm.nih.gov/pubmed/7826551 https://www.ncbi.nlm.nih.gov/pubmed/1676891 https://www.ncbi.nlm.nih.gov/pubmed/1921252 https://www.ncbi.nlm.nih.gov/pubmed/25185125 https://www.ncbi.nlm.nih.gov/pubmed/1921253 https://www.ncbi.nlm.nih.gov/pubmed/9752889 https://www.ncbi.nlm.nih.gov/pubmed/12691602 https://www.ncbi.nlm.nih.gov/pubmed/17425514 https://www.ncbi.nlm.nih.gov/pubmed/17425514   Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Belcampo: Use the Code CarnivoreMD for 20% off!    JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Jon Venus is a physique athlete and former vegan influencer who has been lifting weights for 8 years, the last 5 of which have been as a vegan. With the birth of his son, nagging injuries (herniated disc in his back) and debilitating muscle cramps in mind he recently began to reconsider the science behind a vegan diet and reintroduced animal foods in his diet. His back pain, and muscle cramps improved significantly after this and he is now very interested in promoting open dialogue regarding the importance of animal foods in the human diet.  Time Stamps: 7:41 Start of podcast 8:22 Jon’s story. 15:56 Vegan propaganda films/ humane raising of animals 17:56 How Jon optimized a plant based diet for bodybuilding. 22:11 Leucine. 23:26 Jon’s physique compared to other prominent vegans. 24:41 What prompted Jon to stop being vegan.  31:31 Can you get B12 from dirt?  34:11 Misleading media reports on Jon’s vegan body transformation.  36:41 Muscle cramps on a vegan diet. 39:35 Concerns of vegan diet. 41:06 Cramping on low carbohydrate diets.  44:41 Diet Dogma.  49:35 How does Jon feel after adding meat back into his diet?  55:51 Will Jon eat organ meats? 57:56 Spirituality of hunting. 1:03:41 Sustainability of human life on earth. 1:04:41 Analyzing plant based nutrition science. 1:20:01 Twinkie diet.  1:24:11 Plant based studies (cont.) 1:30:41 Why do triglycerides go up on low fat vegan diets? 1:32:21 Does red meat intake lead to oxidative stress and inflammation. 1:36:21 Epidemiology studies (Epic Oxford). 1:43:41 Problems with food frequency questionnaires. 1:53:31 Asian epidemiology studies. 2:03:41 Problem with ‘’big’’ health organization 2:15:56 Where to find Jon online. 2:16:41 The most radical thing Jon has done recently. References:https://carnivoremd.com/debate/ https://aslopubs.onlinelibrary.wiley.com/doi/abs/10.4319/lo.1969.14.2.0224 https://www.dailystar.co.uk/diet-fitness/vegan-food-recipes-diet-bodybuilder-17040154 https://www.amazon.ca/Tracker-True-Story-Tom-Brown/dp/0425101339 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852765/#:~:text=A%20Plant%2DBased%20Dietary%20Intervention,16%2DWeek%20Randomized%20Clinical%20Trial&text=Nutrients.,%3B%2010(2)%3A%20189. https://www.latimes.com/archives/la-xpm-2010-dec-06-la-he-fitness-twinkie-diet-20101206-story.html https://europepmc.org/article/med/10446033 https://pubmed.ncbi.nlm.nih.gov/1973470/ https://academic.oup.com/jn/article/137/2/363/4664544 https://www.bmj.com/content/366/bmj.l4897 https://pubmed.ncbi.nlm.nih.gov/28469546/ https://pubmed.ncbi.nlm.nih.gov/17299475/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778858/#:~:text=Red%20meat%20intake%20appeared%20to,P%2Dtrend%20%3C%200.01). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191896/#:~:text=Previous%20studies%20of%20the%20relationship,cause%20mortality%20and%20increased%20longevity. https://pubmed.ncbi.nlm.nih.gov/17920112/ https://pubmed.ncbi.nlm.nih.gov/27280539/ Nutrisense (Continuous Glucose Monitor- CGM): www.Nutrisense.io, use the code CarnivoreMD for 20$ off.    BluBlox: www.blublox.com use the code CarnivoreMD for 15% off your order   White Oak Pastures: Use the code CARNIVOREMD at www.whiteoakpastures.com for 10% off your first order!   Belcampo: Use the Code CarnivoreMD for 20% off!    JOOVV: www.joovv.com/paul To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Anya Fernald is the co-founder and CEO of Belcampo. Belcampo operates 27,000 acres of organic farmland in California and processes its own livestock for sale in its own butcher shops and restaurants.   Anya has two decades of leadership and entrepreneurship experience in high- quality, organic and premium foods. Anya has been recognized as one of Inc Magazine’s 100 Female Founders, one of the 40 under 40 by Food & Wine, named a Nifty Fifty by The New York Times, has been profiled in The New Yorker, and has served as a regular judge on Iron Chef America since 2009. Anya’s debut cookbook, Home Cooked, was released in spring 2016 with Ten Speed Press.    Time Stamps:  4:36 Start of Podcast 5:52 Anya's story 11:30 Are our culinary icons healthy?  14:36 How is Belcampo different ? 19:56 Clustered animal feeding operations  20:48 Grass finished vs grass fed beef  29:46 You can't shortcut your diet. 31:36 Factory farmed chicken 35:06 What happens when you give chicken antibiotics? 36:16 What does Anya feed her chicken? 39:16 Biodiversity/rotational grazing/regenerative farming techniques. 44:31 Pictures of Belcampo. (https://belcampo.com/ourpractices/) 47:41 How to incorporate organ meats into your diet. 54:51 Anya’s diet. 1:00:51 Collagen. 1:01:36 How to deal with the stigma of eating red meat as a woman. 1:05:36 The most radical thing Anya has done recently.   To subscribe to my newsletter visit: carnivoremd.com   My contact information:   Book: www.thecarnivorecodebook.com   PATREON: https://www.patreon.com/paulsaladinomd   SOCIAL MEDIA  Instagram: @carnivoremd Website: carnivoremd.com Twitter:@carnivoremd  Facebook: Paul Saladino MD email: drpaul@carnivoremd.com
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Comments (40)

Sean O'Sullivan

Who are these non human zebra hunters he's talking about?

Aug 11th
Reply

Zen Xavier

Hello Dr. Paul, I’m an Environmental Science major in Canada, living two hours outside of Elk Island National Park, which at one time housed all remaining bison in North America. Part of our studies includes rotational grazing practices and regenerative agriculture, and I just wanted to commend you on your passion of bringing this information to the world. As someone who has all but eliminated the symptoms of Crohn’s Disease that I’ve battled for 15 years by following a carnivore diet, and also a student of science wishing to marry my own passion for sustainability and nutrition as a way to fix the woes of the world, I have a question I’ve been dying to ask you: What academic path would you recommend to an ambitious, passionate young scientist with one foot in environmental sustainability, and one foot in nutrition to maximize their impact on the world? Radically, Colbie “Zen” Grieve

Jul 5th
Reply

savagezen

What happens when PUFAs go up and saturated fat goes down? LDL drops, yes. NO CHANGE in cardiovascular events, yes. increase mortality, YES!

Jun 25th
Reply

Maria Stine

Vit D

Jun 12th
Reply

savagezen

Look at the message that mainstream healthcare has gotten us in the last 30, 40, 50 (!) years. We keep getting fatter and sicker. Good job guys!

May 4th
Reply

savagezen

Fascinating stuff!

May 2nd
Reply

savagezen

Paul does a great job of inviting guests with different perspectives to have an open discussion rather than "an echo chamber" as he puts it.

Apr 29th
Reply

savagezen

Giving real facts about sustainability and agricultural!

Apr 23rd
Reply

savagezen

rekt....

Apr 18th
Reply

savagezen

This is amazing work!

Apr 18th
Reply

Mike

I cant listen to her. umm, ah, ummm, ah, ahhhhhh

Apr 16th
Reply

savagezen

Lots of good information here as well. 1-3g of sodium per day might actually be low on a Carnivore / keto diet. Robb Wolf and Mark Sisson frequently cite a minimum of 5g. For me BP has been fickle, but too little sodium or electrolytes overall definitely has drawbacks especially for athletes.

Apr 15th
Reply

savagezen

Another good episode and discussion! The metaphor of your blood stream as a highway is helpful in a lot of ways, but here too. if the highways constantly has a rush hour traffic jam from sugar (and subsequently insulin), then it takes longer or more for micronutrients to get where they need to be. Versus, if the highway is free and clear, you may well need far less of those nutrients because they're getting delivered more efficiently.

Apr 14th
Reply

savagezen

Paul does a great job of inviting a variety of guests to discuss different nutritional concepts. It's refreshing to hear different points of view rather than blatant confirmation biases. #eatmeat

Apr 13th
Reply

Wacey Johnson

I am so happy to hear you discussing regenerative ag- including the intensive rotational grazing, building organic matter in the soil, and improving water filtration. We are farmers and ranchers in the panhandle of Nebraska, and it is no easy task to change the conventional mindset of our neighbors. We have seen significant improvement in our animals health and in our land health by implementing regenerative practices! We are hoping that we can lead by example and eventually include our neighbors on these better practices. Wacey Johnson Whitney, NE Grassland Gleanings LLC

Apr 2nd
Reply

A.J. Olding

by plant medicine journey, does he mean psychedelics?

Apr 1st
Reply

Francisco Diniz

First time I I've listen about type I reversal, it makes sense, as an autoimmune may reverse on an ancestral diet.

Feb 28th
Reply

Teresa May

Great podcast!! I really believe that carnivore is the way. PS... The Final Countdown is NOT one of the best 80s songs...lol

Feb 25th
Reply

A.J. Olding

its starting to feel like half if not more of the people into alternative nutrition were victims of Accutane at some point in their lives.

Feb 18th
Reply

Bekki Boo

What a fantastic episode!! So informative and crammed full of priceless gems! Thank you Doctors

Feb 14th
Reply
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