DiscoverFundamental Health with Paul Saladino, MD
Fundamental Health with Paul Saladino, MD
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Fundamental Health with Paul Saladino, MD

Author: Paul Saladino, MD

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Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.
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This is the third AMA podcast I’ve done and it was a fun one!  Time stamps with questions I answer in this one are below. If you have questions for future AMAs send them to radicalhealth@heartandsoil.co!    Time Stamps:  0:11:08 Ask Me Anything! 0:13:21 What are the best labs to get done? 0:21:49 How do we most effectively share the animal-based lifestyle with friends and family? 0:24:34 Is a plant-based diet more financially sustainable than an animal-based diet? 0:27:03 Zach Bush, Tetrahydrate, and eating dirt 0:32:49 The Scoop on Candida 0:39:15 Natural Honey Lowers Plasma Glucose, C-Reactive Protein, Homocysteine, and Blood Lipids in Healthy, Diabetic, and Hyperlipidemic Subjects: Comparison with Dextrose and Sucrose https://www.liebertpub.com/doi/10.1089/109662004322984789?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed& 0:39:15 Why honey is different than other carbs 0:42:35 Paleoanthropology and the origins of modern disease Https://www.youtube.com/watch?v=3fewDdSUSwg 0:42:35 Why were the ancient Egyptians so unhealthy? 0:46:30 Nutrition and health in agriculturalists and hunter-gatherers https://www.proteinpower.com/nutrition-and-health-in-agriculturalists-and-hunter-gatherers/ 0:48:55 Earliest evidence for caries and exploitation of starchy plant foods in Pleistocene hunter-gatherers from Morocco https://www.pnas.org/content/111/3/954 0:58:53 Are peptide supplements legit? 1:03:23 Diet of ancient Egyptians inferred from stable isotope systematics https://www.sciencedirect.com/science/article/abs/pii/S0305440314000843 1:03:42 Reconstructing Ancient Egyptian Diet through Bone Elemental Analysis Using LIBS (Qubbet el Hawa Cemetery) https://www.hindawi.com/journals/bmri/2015/281056/ 1:04:38 Evidence for dietary change but not landscape use in South African early hominins https://pubmed.ncbi.nlm.nih.gov/22878716/ 1:05:10 Stable isotopes reveal patterns of diet and mobility in the last Neandertals and first modern humans in Europe https://www.nature.com/articles/s41598-019-41033-3 1:05:50 The lowdown on sulforaphane 1:07:20 Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://pubmed.ncbi.nlm.nih.gov/26946249/ 1:08:22 Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965485/ 1:14:10 Antioxidants in food: mere myth or magic medicine? https://pubmed.ncbi.nlm.nih.gov/22059961/ 1:15:50 Is linoleic acid really proven to be unhealthy? 1:15:59 Minnesota coronary experiment Https://www.bmj.com/content/bmj/353/bmj.i1246.full.pdf 1:16:04 Sydney Diet Heart Study https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.27.1_supplement.127.4 1:16:25 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://pubmed.ncbi.nlm.nih.gov/9844997/   -- Heart & Soil: Heartandsoil.co for grass-fed desiccated organ supplements White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.com Let’s Get Checked: www.trylgc.com/carnivoremd Cinder: cindergrill.com/pages/carnivoremd
Short answer: yes!   Just because your blood calcium levels are within normal doesn’t mean you don’t need calcium in your diet.   How can you get this? If you tolerate dairy that’s a good option, but for most, I believe calcium from bones as MCHA (microcrystalline hydroxyapatite) is the best option.    That’s why we made our Bone Matrix supplement at Heart & Soil.     In this video, I discuss evidence for benefits of MCHA, if you should worry about calcium and heart attacks, and a bunch more.    Do you have a calcium source in your diet? If not, you need to check out this video and get your learn on!   For those wondering, the Hadza do eat the ends of bones from birds and small animals like Galagos, as well as breaking bones open to suck out the marrow.  #theremembering   -- Heart & Soil: http://heartandsoil.co
I’m back from Africa - what a trip it was!  I got to spend multiple days hunting, eating, living, dancing, and adventuring with the Hadza of Tanzania… In this week’s podcast episode (Fundamental Health, available at heartandsoil.co, Apple podcasts, and YouTube), @dranthonygustin and I sat down to answer many of your questions about our trip and share some of our biggest takeaways…  We discuss how the Hadza eat, what they don’t eat, how healthy they are, how happy they are, salt?, hunting, eating baboon, and a ton more… I talked about my takeaways from this trip in this week's newsletter - If you didn't get it, you’re missing out! Join the tribe at heartandsoil.co!    Timestamps: 0:09:35 Paul's baboon brainy beard 0:12:49 The "Why" behind the trip 0:17:40 You can't believe everything you read 0:23:54 Bush berries are no joke! 0:27:33 Why do the Hadza hunt baboons | The government restrictions on the Hadza 0:39:39 Tubers as Fallback Foods and Their Impact on Hadza Hunter-Gatherers https://onlinelibrary.wiley.com/doi/abs/10.1002/ajpa.21040 0:39:44 The world's foremost meat enthusiasts 0:47:54 What about prions? 0:50:20 Are we westerners just pansies? 1:00:32 The Hadza's secret to happiness 1:13:02 Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers Https://onlinelibrary.wiley.com/doi/abs/10.1002/ajhb.22919 1:19:24 Hunter-gatherers as models in public health Https://onlinelibrary.wiley.com/doi/full/10.1111/obr.12785 1:20:09 It's not all about diet - The healing power of nature 1:29:58 Gender roles and family life of the Hadza 1:36:38 The immense contentment of the Hadza 1:39:50 Why do the Hadza choose their way of life? 1:50:15 The life expectancy of Hunter-gatherers - The Blue Zones are a myth! 1:59:40 Chronic illness always comes back to seed oils 2:06:54 Why did the Hadza have brown teeth? 2:07:56 The effects of excessive fluoride intake https://ajph.aphapublications.org/doi/pdf/10.2105/AJPH.57.4.651   Heart & Soil: Heartandsoil.co for grass-fed desiccated organ supplements White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.comBlublox: Blublox.com, use “CarnivoreMD” for 15% off  Joovv: www.joovv.com/paul
It’s good to be back in the US. My trip to Tanzania to hunt with the Hadza was amazing, and the meals I shared with them were incredible… The meat we had hunted in the bush earlier that day, along with honey and baobab we had found along the way- truly radical… Ironically, It was much harder to always get good food in “civilization” and this was the hardest part of the trip… In this edition of Controversial Thoughts, I share a bit about these struggles and the “creep” of processed foods into our food supply, making it difficult to obtain really good food unless we are very intentional about what we are eating! #theremembering If you’re not subscribed to my newsletter, you are missing out! Head to heartandsoil.co to join the tribe and get all of my thoughts about my trip, the latest science, and things I think are cool!
Mansal Denton "Little Beaver" is the founder of Sacred Hunting, host of the Mansal Denton Podcast, and the subject of an upcoming documentary BELOW THE DROP exploring our relationship to life and death through hunting.  Feeling insecure in early life, he chased a woman to Europe, which led him to prison. Struggling with shame and confusion of what it meant to be a man, he found his calling with the sacred art of hunting. He now desires to share this practice with more men. His indigenous name comes from a Crow Sun Dance chief. His spiritual lineage is derived from 6 years of mentorship from a Muskogee/Creek medicine man named Will "Star Heart". Time Stamps: 0:09:23 Eating only what you kill 0:12:34 Being spiritually connected with your food 0:22:23 Hunting with the crow 0:28:51 Eating nose to tail | Comanche delicacies 0:40:41 Staying true to your values and lifestyle 0:45:41 Psychedelics! 0:58:56 Hunting in Texas 1:02:46 Remembering your connection with the earth 1:04:39 Food fairytales 1:11:50 Where to find Mansal https://www.choosecandor.com/about-us/ 1:14:48 Masal's TSA-approved mule-deer heart   Heart & Soil: Heartandsoil.co for grass-fed desiccated organ supplements White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.comHelix: Helixsleep.com/carnivoremd for $200 off your mattressSacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt!
Dr. Steven Lin is a world leading functional dentist, TEDx speaker and author of the International #1 Amazon Best Selling Book, The Dental Diet. As a passionate preventative, whole health-advocate, Dr. Lin focuses on the understanding of dental disease through nutritional principles. His work has highlighted that crooked teeth and the orthodontia epidemic are diet based problems and the need for public health policy to prevent braces in the next generation of children. Timestamps: 0:08:13 How did Marilyn Monroe eat? 0:12:26 The Story of Weston A. Price 0:16:41 What’s at the core of all healthy diets? 0:18:51 Where do bioavailable nutrients come from? 0:32:35 Losing your wisdom teeth is not normal 0:35:01 How to make healthy babies 0:42:08 We need a root-cause paradigm 0:50:05 Does sugar cause tooth decay? 0:54:45 Understanding the immune system of your teeth 0:59:30 Where did we go wrong? 1:03:30 Is it ever too late to embrace nutrient-dense diets? 1:06:40 What’s behind bad breath? 1:11:55 The root cause of bruxism (teeth grinding), sleep apnea, and more 1:16:26 The many wonders of the ancestral lifestyle 1:20:28 Debunking the ancestral life expectancy myth 1:23:24 The Dental Diet  https://www.drstevenlin.com/the-dental-diet/ Heart & Soil: Heartandsoil.co for grass-fed desiccated organ supplementsWhite Oak: Use “CarnivoreMD” at whiteoakpastures.comBelcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.com Blublox: Blublox.com, use “CarnivoreMD” for 15% offCinder: cindergrill.com/pages/carnivoremd
I thought it would be appropriate to do this week's Controversial Thoughts video on how I eat #AnimalBased while traveling... I brought all the necessities: stainless steel skillet, induction burner, a jar of liver (yes that is correct... Jar. Of. Liver.), and I've got a bunch of desiccated organ supplements from @heartandsoilsupplements for the rest of the trip including Beef Organs, Gut & Digestion, and Histamine & Immune... Africa, here I come! #theremembering
Dr. Josh Axe, founder of Ancient Nutrition and DrAxe.com, is a certified doctor of natural medicine (DNM), doctor of chiropractic (DC) and clinical nutritionist (CNS) with a passion to help people get healthy by empowering them to use nutrition to fuel their health. He is the bestselling author of KETO DIET, Eat Dirt, and COLLAGEN DIET, and author of the upcoming book Ancient Remedies (Feb 2). Dr. Axe founded the natural health website DrAxe.com, one of the top natural health website in the world today. Most recently, he launched his podcast, The Dr. Axe Show which features interviews with top health influencers such as Dr. Oz, The Skinny Confidential, Dr. Perlmutter, Dr. Will Cole & many more!  Time Stamps:  0:09:06 Podcast begins 0:10:06 Dr. Axe's Approach to Root Cause Medicine 0:16:49 Glandular Therapy in Traditional Chinese Medicine 0:27:23 How medications deplete your body of vital nutrients 0:31:24 Everyone on the planet should be eating organs 0:37:32 Herbs are medicine, not food and not supplements 0:42:42 One man's food is another man's poison 0:50:38 Josh's take on the carnivore diet 0:53:14 The center of every healthy diet 0:55:48 The mysteries of seasonal eating | What Josh's diet looks like 1:00:21 Where to find Dr. Josh Axe -- Heart & Soil: Heartandsoil.co for grass-fed desiccated organ supplements  White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.com Sacred Hunting: www.sacredhunting.com/Paul for $250 off your hunt!
I got COVID, and it’s been very mild.  I believe this is because I am metabolically healthy and the data supports this conclusion. And yet, the media isn’t speaking about this. Madness!
Mary Ruddick is a seasoned medical nutritionist who specializes in metabolic, immune, and nervous system disorders. She is the Director of Nutrition for CaptainSoup.com, Enable Your Healing, The REIGNS Method, and the Back to Joy Program, and she currently travels the globe studying traditional diets and seeing patients online via her private practice.   Time Stamps:   0:11:16 Mary's Dream Penthouse 0:13:09 Mary on the hippo turf 0:16:13 The lion hunt (No lions were harmed in the making of this podcast) 0:20:46 How separated we've become. 0:26:39 Mary Ruddick's backstory 0:39:06 How Mary beat dysautonomia 0:47:54 What the Greeks actually eat (The blue zones are a myth) 0:54:38 Sociodemographic and Lifestyle Statistics of Oldest Old People (>80 Years) Living in Ikaria Island: The Ikaria Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051199/ 0:55:08 Determinants of All-Cause Mortality and Incidence of Cardiovascular Disease (2009 to 2013) in Older Adults: The Ikaria Study of the Blue Zones https://journals.sagepub.com/doi/10.1177/0003319715603185?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed& 0:55:41 Simplicity, purpose, and community: the recipe for a long life 1:00:07 Mary's African adventure and lots of carnivory 1:12:42 Mary eats a raw adrenal gland 1:17:09 The diet of the Shona 1:24:47 The power of traditional diets 1:28:29 Some insight into Mary's practice 1:33:12 [Vitamin K paper] 1:37:55 The role of animal foods in fertility 1:40:15 Mary's closing remarks 1:40:46 Where to find Mary Ruddick Heart & Soil: Heartandsoil.co for desiccated organ supplements  White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.com Helix: Helixsleep.com/carnivoremd for $200 off your mattress Blublox: Blublox.com, use “CarnivoreMD” for 15% off
Dr. O'Mara works with business executives, professional performers and athletes motivated to improve outcomes through innovative techniques of clinical enhancement. Dr. O’Mara is a partner within an innovative medical startup in Minneapolis MN called Lantu which optimizes health. Dr. O’Mara enjoys speaking with audiences about the dramatic changes within the healthcare system immediately ahead following the inevitable reversal of chronic disease and the considerable advantages which it will bring to individuals, organizations, and indeed civilization as a whole.   Time Stamps:   0:09:36 Podcast Begins 0:11:13 Visualizing visceral fat. The fat-burning power of dietary change 0:17:30 Why diet trumps exercise  0:18:41 Weight is the wrong metric  0:25:23 Will all carbs wreck your metabolic health? 0:31:24 Do vegans have visceral fat?  0:38:13 Using our senses to measure health and choose leaders  0:41:10 Premature Atherosclerosis Associated With Monogenic Insulin Resistance https://www.ahajournals.org/doi/10.1161/01.CIR.103.18.2225 0:44:45 Reversing arterial plaque with diet and lifestyle 0:55:29 Dr. Sean's personal story 1:00:14 The scoop on carbs 1:07:21 Fermented foods for gut diversity and optimal health 1:15:42 A high linoleic acid diet exacerbates metabolic responses and gut microbiota dysbiosis in obese rats with diabetes mellitus https://pubmed.ncbi.nlm.nih.gov/30672576/ 1:16:55 How microbiota affect mental health 1:18:57 Fish Oil Attenuates Omega-6 Polyunsaturated Fatty Acid-Induced Dysbiosis and Infectious Colitis but Impairs LPS Dephosphorylation Activity Causing Sepsis https://www.semanticscholar.org/paper/Fish-Oil-Attenuates-Omega-6-Polyunsaturated-Fatty-Ghosh-DeCoffe/cf8ac6686f8ccd48c215c482712430fb41826afe 1:24:15 Video Cuts Off 1:24:38 All about sprinting 1:32:27 Where to find Sean O'mara   Heart & Soil: Heartandsoil.co  Joovv: www.joovv.com/paul White Oak: Use “CarnivoreMD” at whiteoakpastures.com Belcampo: Use “CarnivoreMD” or “Carnivore10” at www.belcampo.com Sacred Hunting: www.sacredhunting.com/paul  
Animal-based vs Keto vs Paleo Though at first glance an #Animalbased diet may look like a ketogenic or paleo diet, there are some key differences. Though a paleo diet includes meat, this type of eating forgets about the incredible nutrient richness found in organs like liver, heart, kidney, etc. A paleo diet also leaves in nuts/seeds/and leafy greens which don't really provide any unique nutrients but do lead to a lot of gas 💨, bloating, and digestive issues for many people. These are full of anti-nutrients and digestive enzyme inhibitors and are best avoided. Though a very low carbohydrate ketogenic diet can be incredibly powerful for many people with diabetes, and obesity, this way of eating isn't really sustainable long term. The fact of the matter is this, eliminating carbs can help with insulin resistance but didn't cause it in the first place. To truly treat these issues we must remove seed oils and excess linoleic acid from our diets. Once you are metabolically healthy, including carbohydrates from the least toxic plant sources (sweet/non-sweet fruit- no fructose is not toxic in fruit) can be a positive addition to your diet! Animal-based diets can take many forms to suit your needs, but don't fall into overly rigid ketogenic dogma by fearing all carbohydrates long term. Cycling in low-carb periods or periods of a carnivore diet is great, but it's also nice to bring in a few low toxicity plant foods from time to time for variety, flavor, color, etc. Just know that if you chose to include nuts/seeds/leafy greens you may run into digestive issues by trending too much toward paleo. Here's to reclaiming your birthright to radical health! #theremembering SOCIAL MEDIA Heart & Soil: https://heartandsoil.co  Instagram: https://www.instagram.com/paulsaladinomd Website: https://www.paulsaladinomd.com  
Dr. Knobbe began his practice of ophthalmology in 1994, after completing his residency training at the University of Colorado Health Sciences Center, in Denver, Colorado, USA. He was certified by the American Board of Ophthalmology in 1997 and has remained board-certified since then. Eye physician and surgeon, Chris A. Knobbe, MD, had been in practice nearly 20 years when, in 2013, he asked himself the question, “Could macular degeneration be a ‘Westernized disease’? Could AMD be a disease that is the result of a Westernized diet?” That question would forever change his life. The hypothesis that Dr. Knobbe would proffer holds that macular degeneration, which is the leading cause of irreversible vision loss and blindness in developed nations, is not only preventable but treatable in the early to moderate stages, with an ancestral diet.   Time Stamps:  0:09:24 Podcast Begins 0:12:39 200 years of nutritional research 0:23:09 Needs a title 60-sec audiogram 0:30:09 Timeline for Processed Food Introductions 0:36:44 Non-negotiable: Animal fats are essential 0:44:17 150 years of Vegetable Oil Consumption 0:49:07 Who's the real culprit? 0:51:46 Heart Disease Deaths vs Sturated fat and Vegetable Oil 1:05:32 Can linoleic acid contribute to coronary artery disease? https://www.researchgate.net/publication/15005994_Can_linoleic_acid_contribute_to_coronary_artery_disease 1:08:12 Why do we blame the carbs? 1:11:35 Sweden vs US adipose Linoleic Acid and obesity 1:14:02 The Case Of Japan 1:27:20 The problem is neither calories nor carbs 1:33:49 Is processed sugar harmful in and of itself? | What carbs to eat 1:43:36 The Case Of Okinawa 1:55:41 Diets could prevent many diseases Https://www.researchgate.net/publication/10673140_Diets_could_prevent_many_diseases 2:02:50 Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467319/ 2:03:29 Unsaturated fatty acids and their oxidation products stimulate CD36 expression in human macrophages https://www.researchgate.net/publication/11260045_Unsaturated_fatty_acids_and_their_oxidation_products_stimulate_CD36_expression_in_human_macrophages 2:04:13 Low-density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC54010/ 2:06:00 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://www.researchgate.net/publication/12880728_A_high_linoleic_acid_diet_increases_oxidative_stress_in_vivo_and_affects_nitric_oxide_metabolism_in_humans 2:10:50 Changes in Dietary Fat Intake Alter Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a) https://www.ahajournals.org/doi/10.1161/01.atv.0000118012.64932.f4 2:11:39 Where to find Chris Knobbe -- Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.whiteoakpastures.com code CarnivoreMD for 10% off first order Belcampo: www.belcampo.com code CarnivoreMD for 20% off BluBlox: www.blublox.com, use code CarnivoreMd for 15% off Sacred Hunting: www.sacredhunting.com/paul for $250 off of your hunt
What could be more controversial than suggesting that coffee might not be the elixir of life it’s cracked up to be?
Lucy Mailing, Ph.D. received her Bachelor’s in Biology from Kalamazoo College and her Ph.D. in Nutritional Sciences from the University of Illinois, where her dissertation research focused on the effects of diet and exercise on the gut microbiome in states of health and disease. Lucy has authored several peer-reviewed journal articles related to the microbiome and health and was named an Emerging Leader in Nutritional Sciences by the American Society for Nutrition in 2017. Lucy has also served as a staff research associate for the Kresser Institute for Functional and Evolutionary Medicine since 2015. Lucy is the founder and sole author of lucymailing.com, a site dedicated to evidence-based articles about the microbiome, gut and skin health, and nutrition. She is regularly invited to speak on gut health around the country and has been recognized as one of the most trusted experts in the integrative health space. Lucy plans to continue her academic training and begin a postdoc in 2020 after a gap year dedicated to writing and other projects.  Time Stamps:  0:08:47 Podcast begins 0:09:55 What is a healthy gut microbiome? 0:12:43 The Microbiome of the Hadza 0:14:25 Enterocyte-Associated Microbiome of the Hadza Hunter-Gatherers https://www.frontiersin.org/articles/10.3389/fmicb.2016.00865/full 0:18:36 Figure: Typical major phyla and genera of the human gut microbiome https://www.researchgate.net/figure/Typical-major-phyla-and-genera-of-the-human-gut-microbiome-reproduced-with-permission_fig1_331990159 0:22:05 Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania https://science.sciencemag.org/content/357/6353/802#:~:text=The%20data%20reveal%20annual%20cyclic,reappear%20in%20a%20subsequent%20season.&text=These%20data%20indicate%20that%20some,and%20abundance%20in%20modernized%20populations. 0:24:38 Pervasive bias in research 0:30:10 Gut microbiome of the Hadza hunter-gatherers https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996546/ 0:31:11 Microbiological dark matter and the infancy of gut microbiology 0:38:17 The Story of Butyrate 0:42:19 Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines https://www.jci.org/articles/view/133371 0:44:04 Figure: Cartoon of the acylcarnitine shuttle and β-oxidation of fatty acids in mitochondria. https://www.researchgate.net/figure/Cartoon-of-the-acylcarnitine-shuttle-and-b-oxidation-of-fatty-acids-in-mitochondria_fig1_323380097 0:46:00 GUT MICROBIAL METABOLOME: REGULATION OF HOST METABOLISM BY SCFAs https://core.ac.uk/download/pdf/77011125.pdf 0:47:50 Fermentation of animal components in strict carnivores: A comparative study with cheetah fecal inoculum https://www.researchgate.net/publication/221789283_Fermentation_of_animal_components_in_strict_carnivores_A_comparative_study_with_cheetah_fecal_inoculum 0:52:50 Diet rapidly and reproducibly alters the human gut microbiome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957428/ 0:55:42 An Expanded Genetic Code Enables Trimethylamine Metabolism in Human Gut Bacteria https://msystems.asm.org/content/5/5/e00413-20/article-info 0:55:42 How animal-based diet's produce risk of cardiovascular disease 0:58:50 No effect of plasma trimethylamine N-Oxide (TMAO) and plasma trimethyllysine (TML) on the association between choline intake and acute myocardial infarction risk in patients with stable angina pectoris https://www.sciencedirect.com/science/article/pii/S2666149720300025 1:00:27 L-Carnitine Supplementation Increases Trimethylamine-N-Oxide but not Markers of Atherosclerosis in Healthy Aged Women https://www.karger.com/Article/Abstract/495037 1:03:12 Ketogenic Diets > High Fiber Diets 1:03:12 Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells https://www.cell.com/cell/fulltext/S0092-8674(20)30490-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420304906%3Fshowall%3Dtrue 1:10:22 Effect of honey in improving the gut microbial balance https://watermark.silverchair.com/fyx015.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAp0wggKZBgkqhkiG9w0BBwagggKKMIIChgIBADCCAn8GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMUBN9HS4m_4yDlucaAgEQgIICUNhQPQ_X2HqAJ4azqDCrr58lLQ6xyaJ7Zk2aKCN55b-zbRJDQkjuIRY0O6AWv46fMXyMjFRAxlfT2wsTeIp3Hl70aDMCoegqkEDxUHQeSKamahl3-4OkPR4l4PhZ011-brRqW4C2exEo-yeKe3T4ERvV3P4FzLoQsgsV_npm8Pb4r4rpdRmiHaTDi6u2Q7fftFH-NHjGQMq8xxV9LYTEKUo_IrCw7gpCcoyw5VoH9QYyGn6dbmbifNlJFqAW41KH-kP91swAZuZJXxJHiH1sqg8z1pfKpPZCUw6blJ5PR5NJBhgApe2CWe_lBC0wsjDNDVnqX-eMji3pS6midB1w4loUJVbOuGuya-BRaJK2UvtfNhzur4IVhgXmIygvGUAmBFdoMKaSJuflGTZTu5KknPLp-_sCSS-zQvDFjWCd_Fkv0PVQU21_WlltwPjR1JplprHEQm7PSXH0kX3K2zUSJ5dHITe_N8PkzeW1bCdxqrO2y5uuk4bXs8wVSrsr1yZze7QmxZpxIXwIRVGO-eJElM31V-5jL7TUnJP8AamI1niGI7mVTmmGbfdtMEaxdjmjaw1lIt05BhTxMZSCswDQRG9gCD5-dQkQ1p0oajFPn02-dvrB0QypF1kekU151KjrQxWdM4v-Yc3aZ12ZOr8Z2OlUIWLQ6lfPRNK2AqwgNGA_yzxUixsD0kjvvvy8ZD4KmVFypxkpLFrZ_tAeK78twOA6yqOUT3VfCm6XDeFZsq7LwUS94nC07VbrrEiePVBwkIcrNaa-KnSQolkEs4SnPyQ 1:12:37 Phenolics and Carbohydrates in Buckwheat Honey Regulate the Human Intestinal Microbiota https://www.hindawi.com/journals/ecam/2020/6432942/ 1:15:20 A deeper look at alpha diversity 1:19:11 Gut Microbiota-Targeted Diets Modulate Human Immune Status https://www.biorxiv.org/content/10.1101/2020.09.30.321448v1.full 1:20:51 The value of fermentation 1:27:16 Gut microbiome response to a modern Paleolithic diet in a Western lifestyle context https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687155/ 1:30:51 Sun exposure and alpha diversity 1:31:31 Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821880/ 1:33:17 How to remedy an urbanized microbiome 1:40:35 What nutrients build a healthy gut lining? 1:43:48 Carnivore MD's Diversity score 1:47:16 Lucy's backstory 1:54:32 Rehabilitating the microbiome 2:03:02 When to not follow a carnivore diet 2:06:44 The many ways of healing the gut 2:09:12 Where to find Lucy Mailing 2:09:52 Lucy Mailing radical independent research -- 30-day Animal-Based Reset: www.AnimalBased30.com  Heart & Soil: www.heartandsoil.co  White Oak Pastures: www.whiteoakpastures.com code CarnivoreMD for 10% off first order Belcampo: www.belcampo.com code CarnivoreMD for 20% off Let’s Get Checked:  www.trylgc.com/carnivoremd  Helix: www.helixsleep.com/carnivoremd
Happy New Year to all!  I’m not a drinker, but I know there are many who will be enjoying alcohol to celebrate the end of this crazy year, and the beginning of one we all hope will be a bit better than 2020. If you’re going to imbibe at New Years or any other time, what’s the least toxic sauce to consume? Find out in this Controversial Thoughts video along with why alcohol causes a hangover and what you can do to mitigate it prior and ameliorate it once it’s besieged you. Hint:  these answers may have to do with things I’ve discussed before like avoiding toxic seed oils to limit lipid peroxidation in your liver from alcohol byproducts, and making sure to get enough nutrients into your diet on a daily basis to optimize your glutathione and NAD/NADH statuses.  If you’re looking to lose weight, or kick more ass in 2021 you should join us at Heart & Soil for our 30 day animal based reset in January. Go to www.AnimalBased30.com to sign up and become part of the tribe that will be starting off the new year right! There will be lots of content, support, and a chance to win some of our desiccated organ supplements as well as signed copies of my book, The Carnivore Code. Welcome to #theremembering.
Find part 1 of this podcast with James, here.    Dr. James DiNicolantonio, is a Doctor of Pharmacy and a cardiovascular research scientist. A well-respected and internationally known scientist and an expert on health and nutrition, he has contributed extensively to health policy and has testified in front of the Canadian Senate regarding the harms of added sugars. He serves as the associate editor of the British Medical Journal’s Open Heart, a journal published in partnership with the British Cardiovascular Society, and is on the editorial advisory boards of several other medical journals. Dr. DiNicolantonio is the author or coauthor of over 250 publications in the medical literature. He also is the author of three bestselling health books, The Salt Fix, Superfuel and The Longevity Solution, as well as his newest book, The Immunity fix which you can find here. You can follow him on Instagram and Twitter @drjamesdinic and on Facebook at Dr. James DiNicolantonio. You can visit his website at drjamesdinic.com. Time stamps:    0:08:11 Podcast begins  0:09:16 How to create metabolic health  0:16:54 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans https://linkinghub.elsevier.com/retrieve/pii/S0952-3278(98)90067-9  0:19:55 Omega six fatty acids and oxidative stress  0:21:07 Premature atherosclerosis associated with monogenic insulin resistance https://www.ahajournals.org/doi/10.1161/01.cir.103.18.2225?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&  0:22:00 Elevated Serum C-Reactive Protein and Free Fatty Acids Among Nondiabetic Carriers of Missense Mutations in the Gene Encoding Lamin A/C (LMNA) With Partial Lipodystrophyhttps://www.ahajournals.org/doi/10.1161/01.atv.0000047460.27435.b8?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed  0:32:46 Answering the fructose question and dispelling keto dogma  0:40:17 What nutrients are required for robust immunity  0:40:17 Is colostrum more effective than vaccines?  0:41:56 Prevention of Influenza Episodes With Colostrum Compared With Vaccination in Healthy and High-Risk Cardiovascular Subjects: The Epidemiologic Study in San Valentinohttps://journals.sagepub.com/doi/10.1177/1076029606295957?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&  0:43:07 Prevention of flu episodes with colostrum and Bifivir compared with vaccination: an epidemiological, registry study https://www.minervamedica.it/en/journals/panminerva-medica/article.php?cod=R41Y2010N04A0269  0:48:05 Some other helpful interventions  0:52:59 All about environmental hormesis  0:57:48 James' thoughts on time-restricted eating  1:42:35 Where to find James DiNicolantonio http://drjamesdinic.com/   Heart & Soil: www.heartandsoil.co    White Oak Pastures: www.whiteoakpastures.com code CarnivoreMD for 10% off first order   Belcampo: www.belcampo.com code CarnivoreMD for 20% off   Let’s Get Checked:  www.trylgc.com/carnivoremd  BluBlox: www.blublox.com, CarnivoreMD for 15% off
The next 10 days are your downfall, admit it.  You’re in good company, they are the downfall of most but they don’t have to be! Here are 3 simple but impactful ways to change your eating habits over the next 10 days to prevent weight gain. Come January 1st, you’ll be glad you did these things, trust me. Cliff notes version:  Avoid seed oils (duh) Include nutrient-rich organs and animal fat prior to meals Choose nose to tail animal foods FIRST when you are eating Voila! And just like that you improved your metabolic health, waistline, energy, sleep, and mood in a time period when most get fat. You’re welcome, and welcome to #theremembering.
Dr. James DiNicolantonio, is a Doctor of Pharmacy and a cardiovascular research scientist. A well-respected and internationally known scientist and an expert on health and nutrition, he has contributed extensively to health policy and has testified in front of the Canadian Senate regarding the harms of added sugars. He serves as the associate editor of the British Medical Journal’s Open Heart, a journal published in partnership with the British Cardiovascular Society, and is on the editorial advisory boards of several other medical journals. Dr. DiNicolantonio is the author or coauthor of over 250 publications in the medical literature. He also is the author of three bestselling health books, The Salt Fix, Superfuel and The Longevity Solution, as well as his newest book, The Immunity fix which you can find here. You can follow him on Instagram and Twitter @drjamesdinic and on Facebook at Dr. James DiNicolantonio. You can visit his website at drjamesdinic.com. Time Stamps:  0:07:19 Podcast Begins 0:08:16 The role of animals in pandemics 0:14:22 Regenerative agriculture will save the world 0:18:06 The nutrient-density of regenerative beef  0:19:46 The power of sunlight and fresh air 0:23:29 Salty air and hypertonic salt solutions 0:28:41 What determines poor Covid 19 outcomes 0:33:45 Fixing metabolic health with a strict diet. 0:39:10 Should we trust in the Covid 19 vaccine? 0:45:20 How does the immune system get disordered 0:47:29 Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357061/ 0:49:42 Impact of Obesity and Metabolic Syndrome on Immunity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717890/ 0:50:17 Understanding cross-sensitivity of coronaviruses     Heart & Soil: www.heartandsoil.co    White Oak Pastures: www.whiteoakpastures.com code CarnivoreMD for 10% off first order   Belcampo: www.belcampo.com code CarnivoreMD for 20% off Let’s Get Checked:  www.trylgc.com/carnivoremd
In short, yes (as long as you tolerate it)!   Milk, yogurt, butter, ghee and colostrum are amazing sources of nutrients that have been highly valued by many indigenous groups for millenia. Dairy has a long tradition in Northern Europe, and among hunter-gatherer groups like the Maasai, or historically among groups like the Mongols (think warriors whose diets were basically milk, meat, and organs).    Dairy isn’t for everyone, and some may have issues with lactose (a deficiency on the lactase enzyme), or the casein and whey proteins within it. Personally I can’t tolerate dairy, but I am incredibly jealous of all of you who can because it’s delicious and nutrient-rch.  In this controversial thoughts video I discuss evidence linking dairy with cancer (most observational studies suggest an inverse correlation, i.e. higher intakes are associated with better outcomes), most of which suggests dairy is totally safe. I also discuss colostrum (the immunoglobulin-rich first milk from mammals) in detail. This stuff is chocked FULL of unique peptides, immunoglobulins, and growth factors that aid in gut healing, wound healing, and immune fortification.    Colostrum has even been studied in comparison to flu vaccinations in small studies and found to be just as effective at preventing influenza. More research is needed here but the findings from at least two studies are intriguing.    If you have questions about dairy in your diet, this video is for you! #theremembering  
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Comments (52)

Abio Genesis

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Feb 9th
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Abio Genesis

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Feb 8th
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Abio Genesis

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Feb 7th
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Abio Genesis

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Feb 6th
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Abio Genesis

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Feb 5th
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Abio Genesis

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Feb 3rd
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Abio Genesis

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Jan 30th
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Abio Genesis

+ power point

Jan 27th
Reply

Abio Genesis

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Jan 26th
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Nathan Phua

8:55 Why WHO thinks red meat causes cancer

Dec 12th
Reply

Mixed martial

give credit to aajanous frank tufano and derek nance

Nov 6th
Reply

Mixed martial

give credit to aajanous frank tufano and derek nance

Nov 6th
Reply

Sean O'Sullivan

Who are these non human zebra hunters he's talking about?

Aug 11th
Reply

Zen Xavier

Hello Dr. Paul, I’m an Environmental Science major in Canada, living two hours outside of Elk Island National Park, which at one time housed all remaining bison in North America. Part of our studies includes rotational grazing practices and regenerative agriculture, and I just wanted to commend you on your passion of bringing this information to the world. As someone who has all but eliminated the symptoms of Crohn’s Disease that I’ve battled for 15 years by following a carnivore diet, and also a student of science wishing to marry my own passion for sustainability and nutrition as a way to fix the woes of the world, I have a question I’ve been dying to ask you: What academic path would you recommend to an ambitious, passionate young scientist with one foot in environmental sustainability, and one foot in nutrition to maximize their impact on the world? Radically, Colbie “Zen” Grieve

Jul 5th
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savagezen

What happens when PUFAs go up and saturated fat goes down? LDL drops, yes. NO CHANGE in cardiovascular events, yes. increase mortality, YES!

Jun 25th
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Maria Stine

Vit D

Jun 12th
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savagezen

Look at the message that mainstream healthcare has gotten us in the last 30, 40, 50 (!) years. We keep getting fatter and sicker. Good job guys!

May 4th
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savagezen

Fascinating stuff!

May 2nd
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savagezen

Paul does a great job of inviting guests with different perspectives to have an open discussion rather than "an echo chamber" as he puts it.

Apr 29th
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savagezen

Giving real facts about sustainability and agricultural!

Apr 23rd
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