The Grenz Zone

Let’s continue learning about biologics! In the second episode of this three part interview series with Dr. Krishnamurthy, we continue to learn about the indications for biologic use and other relevant considerations when prescribing biologics. This is some complicated stuff, and we are grateful to Dr. K for breaking it down for us and giving us some great pearls along the way!  Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Get excited for some highly requested episodes! In this first episode of a three part interview series with Dr. Krishnamurthy, we will start to break down biologics: what are they, how do they work, and what makes a patient with psoriasis a good candidate for therapy with a biologic?  Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson (bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Bumps in a baby?! Say it ain’t so! In this episode, we discuss the differential diagnosis for bumps in infants and young children ranging from benign lesions, such as milia, to more serious lesions, such as pediatric melanomas.  References: Bouraoui S, Mlika M, Kort R, Cherif F, Lahmar A, Sabeh M. Miliary osteoma cutis of the face. J Dermatol Case Rep. 2011;5(4):77-81. doi:10.3315/jdcr.2011.1082 Gupta D, Frieden I, Cordoro K, Kashani-Sabet, M. and McCalmont, T. Evidence for modification of the ABCDE criteria for pediatric melanoma. J Am Acad Dermatol, 2012;66(4). doi.org/10.1016/j.jaad.2011.11.011 Paller AS, Mancini AJ. Hurwitz Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence. Edinburgh: Elsevier; 2016.  Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

In this episode, we touch on another common presentation to dermatology offices – hyperhidrosis.  Sweaty palms, sweaty pits, sweaty anything can be very frustrating for patients and very rewarding to get adequate treatment. We’ll discuss pearls in the diagnosis, differential, and treatment toolkit! References: Nawrocki S, Cha J. The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up. J Am Acad Dermatol. 2019;81(3):657-666. doi:10.1016/j.jaad.2018.12.071 Nawrocki S, Cha J. The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Therapeutic options. J Am Acad Dermatol. 2019;81(3):669-680. doi:10.1016/j.jaad.2018.11.066 Hu Y, Converse C, Lyons MC, Hsu WH. Neural control of sweat secretion: a review. Br J Dermatol. 2018;178(6):1246-1256. doi:10.1111/bjd.15808 Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

In the third episode of season 3, we finish our three episode series on hidradenitis suppurativa with a discussion of HS management pearls with Dr. Joslyn Kirby,  the vice chair of education and program director for the Department of Dermatology at Penn State. She offers her invaluable insight as to how to approach discussion of the disease and its treatment with patients and offers tips for getting insurance company approval for HS treatment with biologic agents.  Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

In the second episode of season 3, we continue our three episode series on hidradenitis suppurativa with a discussion of the pathogenesis, comorbidities, and treatment of HS. We break down the complex treatment of HS into five categories including trigger avoidance, topical therapies, systemic oral agents, biologics, and surgery.  References: Alikhan A, Sayed C, Alavi A, et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. J Am Acad Dermatol. 2019;81(1):76-90. doi:10.1016/j.jaad.2019.02.067 Alikhan A, Sayed C, Alavi A, et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. J Am Acad Dermatol. 2019;81(1):91-101. doi:10.1016/j.jaad.2019.02.068 Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

In the first episode of season 3, we begin our three episode series on hidradenitis suppurativa with a discussion of the HS patient experience with Dr. Katelyn Baker, a doctor of clinical psychology who graciously shares with us her own personal experiences as a patient with HS. She also offers some suggestions for healthcare providers to help them make their own HS patients feel comfortable and empowered in working together to manage and treat their disease. Dr. Katelyn Baker’s Social Media Platforms: Tiktok: @thatfatdoctor Instagram: @thatfatdoctor YouTube: @ThatFatDoctor Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson (bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

We round out season 2 and the vascular reaction pattern by discussing vascular tumors and malformations.  With the help of Dr. Binky, we will cover congenital and infantile hemangiomas, PHACES syndrome,  port wine stains, Sturge-Weber syndrome, pyogenic granulomas, angiokeratomas, tufted angiomas, glomus tumors, and angiolymphoid hyperplasia with eosinophilia, Kaposi’s sarcoma, and angiosarcoma. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

After some dense content in the past 4 episodes on vasculitis, vasculopathy, and retiform purpura, we bring it all together at the patient’s bedside with Dr. Jerry Titus-Vasculitis and walk through how to get a thorough H&P for a patient with a purpuric rash, along with discuss the basics of workup and treatment. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Like erythroderma, retiform (branching/angulated) purpura is not the diagnosis – it’s a clinical sign hinting towards a variety of underlying conditions, which can be emergent and deadly.  Dr. DOOD gives us clinical pearls on the differential diagnosis and approach to patients with retiform purpura. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Dr. Grumpypants replaces his former rival Jerry Titus-Vasculitis for a discussion on the many causes of vasculopathy, including the inherited and acquired disorders of the coagulation pathway and platelets.  We also discuss embolic disorders, pigmented purpuras, and hypergammaglobulinemic purpura of Waldenstrom. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Like all of dermatology, vasculitis and purpuric rashes are a complicated topic that can be difficult to know where to start with.  We simplify both vasculitis and vasculopathies in a 5-episode series, this time with the corny gameshow “Name That Vasculitis”, hosted by the even cornier Dr. Jerry Titus-Vasculitis.  Who?!?!  We finish the small and medium-vessel vasculitides by covering ANCA vasculitis, then discuss medium-vessel vasculitis with polyarteritis nodosa and Kawasaki disease, large-vessel vasculitis caused by giant cell arteritis and Takayasu’s arteritis, along with septic vasculitis. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Like all of dermatology, vasculitis and purpuric rashes are a complicated topic that can be difficult to know where to start with.  We simplify both vasculitis and vasculopathies in a 5-episode series, this time with the corny gameshow “Name That Vasculitis”, hosted by the even cornier Dr. Jerry Titus-Vasculitis.  Who?!?!  This episode covers the definitions of vasculitis and vasculopathy, types of purpura, the overall differential diagnosis for vasculitis based on vessel size, and discusses the small vessel vasculitides (cutaneous small vessel vasculitis, Henoch-Schonlein purpura, and urticarial vasculitis), along with starting the small and medium-vessel vasculitides by covering types 2 and 3 cryoglobulinemias. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.

Around 10-20% of the population, including Dr. Grumpypants, will develop hives (urticaria) in their lifetime, and it can be more complicated than you think.  We discuss its pathogenesis, differential diagnosis, workup, and management. Connect with us: Facebook   │   Instagram www.grenzzonederm.com – includes excellent episode study guides! Feel free to contact us with any feedback through our website or at grenzzonederm@gmail.com If you enjoy the podcast, please help us out by sharing the episodes with a friend and by leaving a 5-star review.  When he’s up for it, Dr. Grumpypants will read his favorite recent review on our social media accounts, will it be yours?  Musical support provided by:         •       Daniel Thompson(bass)          •       Alec Tackmann (drums)           •       Thomas and the Shakes   Terms of use:  The views, information, or opinions expressed during this podcast: 1) are for general informational purposes, 2) are solely those of the individuals involved, and 3) do not represent those of Orange Park Medical Center, Olmsted Medical Center, or their affiliates.  By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others, including but not limited to patients that you are treating. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Pearl Podcasting, LLC, any guests or contributors to the podcast, or any employees, independent contractors, associates, or affiliates of Pearl Podcasting, LLC be responsible for damages arising from use of the podcast.