The Neurostimulation Podcast #36: How Adenosine Bridges Rapid Antidepressant Therapies – Insights from Ketamine and ECT ResearchHost: Dr. Michael Passmore, Clinical Associate Professor, UBC PsychiatryEpisode Summary: In this episode, Dr. Passmore explores groundbreaking research revealing how adenosine—a natural brain chemical—may be the key link between two of the fastest-acting antidepressant treatments: ketamine and electroconvulsive therapy (ECT). The discussion covers:The science behind adenosine’s role in mood regulation and how both ketamine and ECT trigger rapid antidepressant effects via adenosine pathways.Key findings from a recent Nature study using mouse models, including the necessity and sufficiency of adenosine A1 and A2A receptors for treatment response.The implications for clinical practice, including the potential impact of caffeine (which blocks adenosine) on treatment outcomes.Why standardizing caffeine intake may be important for patients undergoing ketamine or ECT therapy.The importance of translating preclinical findings into human studies and the need for further research.Key Takeaways:Adenosine may act as a “common language” for rapid antidepressant effects in both ketamine and ECT.Caffeine could potentially interfere with these treatments by blocking adenosine receptors—patients and clinicians should be aware of this variable.The research is preclinical (in mice), but it lays the groundwork for future human studies and smarter, more targeted therapies.Resources & Links:Extended data, figures, and the full research paper are linked in the show notes.For more information, check the episode’s resource section.Disclaimer:This podcast is for educational purposes only and does not constitute medical advice. Always consult your healthcare provider for personal medical guidance.Connect & Share:If you enjoyed this episode, please like, subscribe, and share with friends or colleagues who might benefit. Join the conversation in the comments—your feedback helps shape future episodes!Stay curious, and tune in next time for more insights into neuroscience, clinical neurostimulation, and interventional mental health.Contact:Questions, ideas, or feedback? Leave a comment or reach out via the podcast’s contact channels.
Transforming Mental Health: The Power of Neurostimulation and Innovative Therapies with Sam PetersonIn this episode of the Neurostimulation podcast, host Dr. Michael Passmore interviews Sam Peterson, a former army bomb technician and co-founder of Patriot Power Up, who now leads Mind Spa Denver. Sam shares his personal journey from battling PTSD and traumatic brain injury (TBI) to pioneering innovative mental health therapies. He explains the neurobiology of trauma, the impact of neuroinflammation, and the effectiveness of treatments like Ketamine, transcranial magnetic stimulation (TMS), and hyperbaric oxygen therapy in providing rapid relief and promoting neuroplasticity. The discussion highlights the importance of innovative, individualized approaches to mental health care for veterans, first responders, and trauma survivors, aiming to revolutionize treatment protocols and improve lives.https://www.mindspadenver.com/00:00 Introduction to Sam Peterson and His Mission01:48 Sam's Journey from Battlefield to Mental Health Advocate03:03 Understanding the Neurobiology of Trauma04:39 The Role of Inflammation in Mental Health12:36 Innovative Treatments at Mind Spa Denver22:55 Success Stories and Future Vision27:17 Challenges and Opportunities in Mental Health Care36:13 Conclusion and Final Thoughts
Exploring tACS: Current Research and Future Potentials in NeuropsychiatryIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore hosts Dr. Osama Elyamani, a psychiatrist and neuroscientist. They discuss the emerging applications of transcranial alternating current stimulation (tACS) in psychiatry, including its potential as a research tool and therapeutic intervention. They delve into the science of brain oscillations, the clinical evidence surrounding tACS, and future prospects in the field. Particular attention is given to the distinctions between tACS, TMS, and tDCS, as well as the limitations and safety considerations of these neurostimulation techniques. The conversation also touches on the significance of symptom-based approaches in psychiatric treatment and the potential for tACS to aid in diagnosing and treating disorders like depression and schizophrenia. Dr. Elyamani provides insights into ongoing research, future directions, and offers advice for young researchers entering the field.Dr. Osama Elyamany (PhD) is currently a postdoctoral researcher and resident psychiatrist at the Centre of Psychiatry at Justus Liebig University Giessen.He is working on research projects investigating brain oscillations in psychiatric disorders using EEG and fMRI, aiming to develop targeted therapies through pharmacological substances and neurostimulation techniques like tACS and TMS.Email Address: osama.elyamany@psychiat.med.uni-giessen.deWebsite: https://www.ukgm.de/ugm_2/deu/ugi_psy/ugi_psy_team.phpLinkedIn: https://www.linkedin.com/in/osama-elyamany/00:00 Introduction and Guest Welcome01:39 Dr. Elyamani's Background and Research Focus02:54 Understanding Brain Oscillations and tACS07:31 Comparing tACS with Other Neurostimulation Techniques11:12 Potential Therapeutic Applications of tACS20:42 Challenges and Future Directions in tACS Research35:20 Safety and Practicality of tACS41:10 Closing Remarks and Future Outlook
Neurostimulation Podcast – Chapter 8: Stimulation Parameters and Their ReportingHost: Dr. Michael Passmore, Clinical Associate Professor, UBCEpisode Overview: In this episode, Dr. Passmore unpacks Chapter 8 of the "Practical Guide to Transcranial Direct Current Stimulation (tDCS)" textbook, focusing on the critical role of stimulation parameters and the importance of transparent reporting in tDCS research and clinical practice.Key Topics Covered:What are stimulation parameters in tDCS?Electrode size, shape, material, and placement (montage)Current intensity, polarity, and densityDuration and ramping protocolContextual factors (e.g., task during stimulation, number of sessions)Why reporting parameters matters:Ensures reproducibility and comparability of studiesPrevents misinterpretation of results due to hidden variablesBuilds trust and transparency in the fieldChallenges in the parameter space:Vast combinations of settings make standardization difficultInter-individual variability (e.g., skull thickness, brain anatomy) affects outcomesPractical guidelines for reporting:Use standardized coordinate systems for placementReport all relevant details, including tolerability and side effectsTreat parameter reporting as a checklist for every study or clinical reportThe bottom line:Parameters are the "recipe" for tDCSSmall differences can lead to big changes in outcomesTransparent, consistent reporting is essential for scientific progress and patient safetyNotable Quotes:“Without the full recipe, you can’t reproduce the results.”“The details aren’t just technicalities—they are the science.”Next Episode Teaser:A look ahead to Chapter 9: How computational modeling helps make sense of the complex parameter space and moves the field toward personalized dosing.Call to Action:Share the episode with colleagues or anyone interested in neurostimulation.Leave comments, questions, or topic suggestions for future episodes.Thank you for listening to the Neurostimulation Podcast!
Neurostimulation Podcast – Aug 30, 2025Guests: Professor Bernhard Hommel & Professor Lorenza ColzatoHost: Dr. Michael PassmoreEpisode Overview:In this episode, Dr. Passmore is joined by Professors Hommel and Colzato to discuss their recent research on metacontrol—the brain’s ability to balance persistence and flexibility—and how it can be modulated using paired anodal tDCS and methylphenidate. The conversation explores the implications of reducing cortical noise, the significance of the aperiodic EEG exponent, and the potential for individualized, biomarker-guided neurostimulation treatments.Key Topics:Definition and importance of metacontrol in cognitive functionThe spectrum between persistence and flexibility in the brainIndividual variability in cognitive control and its clinical relevanceThe study: combining anodal tDCS over the right inferior frontal cortex with methylphenidateFindings: reduction in cortical noise during task processing, indexed by a rise in the aperiodic EEG exponent (especially at fCZ)Implications for ADHD, OCD, and other disorders affecting attention and cognitive controlThe need for replication and standardization before clinical applicationCultural differences in treatment approaches (pharmacological vs. neurostimulation)The future of personalized, feedback-driven neurostimulation and neurofeedbackTakeaways:Metacontrol is a modifiable brain function, not just an abstract concept.Combined tDCS and methylphenidate can reduce cortical noise during tasks, with the aperiodic exponent as a promising EEG marker.The path to clinical application will require safety, individualization, and further research.Links & Resources:Study in Brain Stimulation Journal:https://www.brainstimjrnl.com/article/S1935-861X(25)00081-6/fulltextAdditional lab content and resources:https://www.bernhard-hommel.eu/enThe Metacontrol Lab YouTube channelhttps://www.youtube.com/@metacontrol-2024Disclaimer:This episode is for educational purposes only and does not constitute medical advice. Do not attempt brain stimulation or drug-device combinations outside of supervised clinical research.Connect:If you enjoyed this episode, please like, subscribe, and leave your questions or comments below. Let us know what topics you’d like to hear about in future episodes!
Show Notes: The Neurostimulation Podcast – Episode #30 with Dr. Jennifer RodgerGuest: Dr. Jennifer Rodger, Professor at the University of Western Australia and Head of the Brain Plasticity Research Group at the Perron InstituteRelease Date: August 2, 2025Episode Overview:In this episode, host Michael Passmore sits down with Dr. Jennifer Rodger, a leading neuroscientist whose lab is pioneering research into the mechanisms and safety of low-intensity, repetitive transcranial magnetic stimulation (rTMS), especially in the developing brain.Dr. Rodger shares her unique journey from biochemistry to neuroscience, her initial skepticism about TMS, and how her team’s animal model research is helping to unravel the effects and potential of rTMS in both clinical and research settings. The conversation covers:The challenges and breakthroughs in miniaturizing TMS coils for animal studiesKey findings from recent studies on rTMS in adolescent mice, including effects on brain plasticity and behaviorThe translational bridge between animal research and human clinical applications, especially for youth and neurodevelopmental disordersThe importance of safety, evidence-based innovation, and publishing negative results in scientific researchThe future of tailored neurostimulation protocols and the need for collaboration across labs and disciplinesKey Takeaways:rTMS shows promise for treating neuropsychiatric conditions in youth, but careful, long-term research is essential to ensure safety and efficacy.Animal models provide valuable insights into the mechanisms and potential risks of neurostimulation, especially during critical developmental windows.Publishing negative results is crucial for scientific progress and helps guide future research directions.The field of neurostimulation is rapidly evolving, with opportunities for more personalized and integrated treatment approaches.Resources & Links:Dr. Rodger’s lab and research group: https://brainplasticitylab.org/ https://www.perroninstitute.org/research/research-groups/jennifer-rodger/https://www.perroninstitute.org/research/our-focus-areas/brain-plasticity/Recent publications and studies discussed:Our first low intensity rTMS paper is:Rodger J, Mo C, Wilks T, Dunlop SA, Sherrard RM. Transcranial pulsed magnetic field stimulation facilitates reorganization of abnormal neural circuits and corrects Behavioral deficits without disrupting normal connectivity. FASEB J. 2012 Apr;26(4):1593-606. https://pubmed.ncbi.nlm.nih.gov/22223750/Description of miniaturised coil design:Tang AD, Lowe AS, Garrett AR, Woodward R, Bennett W, Canty AJ, Garry MI, Hinder MR, Summers JJ, Gersner R, Rotenberg A, Thickbroom G, Walton J, Rodger J. Construction and Evaluation of Rodent-Specific rTMS Coils. Front Neural Circuits. 2016 Jun 30;10:47. https://pubmed.ncbi.nlm.nih.gov/27445702/An exhaustive recent review of low intensity rTMS:Moretti J, Rodger J. A little goes a long way: Neurobiological effects of low intensity rTMS and implications for mechanisms of rTMS. Curr Res Neurobiol. 2022 Feb 23;3:100033. https://pubmed.ncbi.nlm.nih.gov/36685761/The work exploring rTMS and endogenous brain activity:Poh EZ, Green C, Agostinelli L, Penrose-Menz M, Karl AK, Harvey AR, Rodger J. Manipulating the Level of Sensorimotor Stimulation during LI-rTMS Can Improve Visual Circuit Reorganisation in Adult Ephrin-A2A5-/- Mice. Int J Mol Sci. 2022 Feb 22;23(5):2418. https://pubmed.ncbi.nlm.nih.gov/35269561/The recent paper about rTMS in adolescent mice is:Tomar M, Pow JJ, Penrose-Menz MA, Beros JL, Miljevic A, Meloni B, Rodger J. Low intensity rTMS in adolescent mice affects visuomotor behaviour with no impact on visual topography. Brain Stimul. 2025...
Deep Dive into tDCS Methodology: Key Considerations and Protocol DesignsIn this episode of The Neurostimulation Podcast, we review chapter seven of the Practical Guide to Transcranial Direct Current Stimulation (tDCS), which focuses on the methodological considerations for selecting tDCS protocols and devices. We discuss important factors such as electrode size and placement, stimulation intensity and duration, and the timing of tDCS sessions. The episode also covers the decision-making framework for clinicians, population-specific adjustments, and the comparison between clinic-based and home-based device use. The role of behavioral tasks during tDCS and the importance of methodological rigor in tDCS research and clinical practice are emphasized. Listeners are encouraged to understand the crucial elements of proper tDCS setup to ensure effective and replicable results.00:00 Introduction to Chapter Seven Review01:17 Importance of Methodology in tDCS01:57 tDCS Decision Matrix02:44 Defining Research and Therapy Goals03:25 Key Variables in Protocol Design05:11 Standalone vs. Adjunctive tDCS06:16 Population-Specific Considerations07:41 Clinic-Based vs. Home-Based Device Use09:13 Session Frequency and Repetition10:39 Integration with Behavioral Tasks11:15 Final Thoughts and Conclusion
Neurostimulation Podcast – Chapter 6: tDCS Safety – Myths, Evidence, and Best PracticesEpisode Overview:In this episode, host Dr. Michael Passmore explores Chapter 6 of the "Practical Guide to Transcranial Direct Current Stimulation: Principles, Procedures, and Applications." The focus is on the safety of tDCS (transcranial direct current stimulation), addressing common myths, reviewing the latest research, and outlining best practices for both clinical and home use.Key Topics Covered:Introduction to tDCS safety and the framework for evaluationDistinction between adverse events and adverse effectsReview of evidence from over 33,000 tDCS sessions and 1,000+ individualsInsights from animal studies and their relevance to human safetyRisk assessment protocols in both animal and human studiesSafety considerations for vulnerable populations (children, stroke survivors, epilepsy, individuals with implants)Home use of tDCS: evidence, compliance, and telehealth supervisionDebunking common myths about tDCS safety:Myth 1: tDCS hasn’t been tested long enoughMyth 2: tDCS is dangerous for older adultsMyth 3: tDCS can cause permanent brain damageCommon mild side effects and how to prevent themReal-world safety guidelines and recommendations for practitioners and researchersThe importance of ongoing vigilance, ethics, and future directions in tDCS safety researchTakeaway Message:When applied responsibly and following evidence-based protocols, tDCS is one of the safest forms of neuromodulation available today. Home use is safe under supervision, and vulnerable groups can be included with tailored protocols. Ongoing research and monitoring will continue to refine best practices.Resources & Links:"Practical Guide to Transcranial Direct Current Stimulation: Principles, Procedures, and Applications"For questions, comments, or topic suggestions, leave a comment below or reach out via the podcast’s contact page.Connect with Us:Don’t forget to like, subscribe, and leave a review! Share this episode with colleagues, patients, or anyone interested in the science and safety of tDCS.Stay Curious, Stay Informed!
Aging with Independence and Innovation: Jennifer Cain Birkmose on the Future of Senior CareIn this episode of the Neurostimulation Podcast, host Michael Passmore discusses senior care innovations with guest Jennifer Cain Birkmose. Jennifer, a pioneering entrepreneur and global health leader, co-founded Viva Valet, a concierge-style service aimed at helping seniors live independently at home for as long as possible. The platform offers comprehensive services including in-home adjustments, technology integration, and safety checks. The episode touches on Jennifer’s methodologies, such as using ethnographic research and involving seniors in beta testing, to ensure user-friendly design. Additionally, Jennifer shares insights from her role as a UN advisor on aging and technology and emphasizes the importance of respect, agency, and social connections in senior care. The conversation concludes with a vision for the future of aging, highlighting the expected societal shifts as the senior population grows.Check out Jennifer's senior's care & support services at Viva Valet https://www.vivavalet.com00:00 Introduction to the Neurostimulation Podcast01:38 Meet Jennifer Cain Birkmose: Innovator in Senior Services04:26 The Viva Valet Platform: Revolutionizing Senior Independence06:25 Challenges and Solutions in Senior Care11:16 User Experience and Technology Integration27:00 Combating Fraud and Ensuring Safety for Seniors33:55 Global Advocacy and Future Directions38:24 Understanding Customer Needs and Bridging Gaps38:46 Resources and Initiatives at Viva Valet39:43 Global Aging and Cultural Commonalities40:24 The Importance of Agency and Independence44:04 Aging with Reverence and Play45:19 Improv and Its Impact on Older Adults54:48 Future Predictions for Aging by 203501:01:55 Closing Remarks and Final Thoughts01:08:13 Podcast Outro and Call to Action
Understanding tDCS: Neurophysiological Insights and Clinical Applications | Neurostimulation PodcastIn this episode of the Neurostimulation Podcast, hosted by Michael Passmore, we delve into Chapter 5 of the 'Practical Guide to Transcranial Direct Current Stimulation.' The episode explores how tDCS modulates neurophysiological and functional outcomes. We discuss the neurophysiological principles behind tDCS, including various methods like TMS, EEG, fMRI, and PET for measuring its effects. The importance of state-dependent neuromodulation and personalized treatment through computational modeling is also highlighted. Finally, the episode examines the clinical implications of tDCS in conditions like stroke recovery, depression, and Alzheimer's disease. Tune in to understand how tDCS is shaping neuroscience and clinical practices.00:00 Introduction to the Neurostimulation Podcast00:47 Exploring Chapter Five of the tDCS Textbook01:52 Understanding Neurophysiological Outcomes02:34 Tools for Measuring tDCS Effects03:41 Regional and Network Effects of tDCS05:16 State-Dependent Neuromodulation06:36 Modeling and Personalized Treatment07:23 Connecting Brain Changes to Behavior08:19 Challenges and Clinical Implications09:07 Conclusion and Future Directions
Exploring Advanced Applications of tDCS: Beyond the BrainIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore continues exploring transcranial direct current stimulation (tDCS) based on 'The Practical Guide to Transcranial Direct Current Stimulation.' He discusses the expansion of DC-based neuromodulation beyond traditional brain applications to the spinal cord and cerebellum. The episode covers three primary targets of DC stimulation: tDCS, cerebellar DC stimulation, and transcutaneous spinal DC stimulation (tsDCS). Additionally, Dr. Passmore delves into electrode setup, clinical applications, home-based treatments, and the challenges and future directions of this evolving field. Tune in to learn about the potential transformative impacts of these techniques on neurological and psychiatric care.00:00 Introduction to the Neurostimulation Podcast01:17 Exploring DC-Based Neuromodulation02:34 Understanding Electrode Design and Placement03:27 tDCS: The Most Researched Form of DC Neurostimulation04:14 Cerebellar DC Stimulation: Beyond Motor Control06:07 Spinal Cord Stimulation: tsDCS Applications07:08 Home-Based Applications and Safety Considerations08:11 Clinical Applications and Case Highlights09:05 Challenges and Future Directions in DC Neuromodulation11:04 Conclusion and Final Thoughts
Exploring Deep Brain Stimulation & Cognitive Function with Dr. David Blake | Neurostimulation PodcastJoin Michael Passmore, clinical associate professor in Psychiatry at the University of British Columbia, as he hosts Dr. David Blake, professor of neuroscience and regenerative medicine at Augusta University. In this episode, they delve into Dr. Blake's groundbreaking research on deep brain stimulation (DBS) and its effects on aging, cognitive function, and neuroplasticity. They discuss the latest findings presented at the 2025 Brain Stimulation Conference in Kobe, Japan, exploring the impact of DBS on neurotrophic markers in cerebrospinal fluid. This fascinating conversation unravels the potential of DBS in treating age-related cognitive decline, Alzheimer's disease, and broader applications such as Parkinson's disease and other neurocognitive disorders. Tune in to discover how Dr. Blake's interdisciplinary approach could revolutionize neurotherapeutics.Blake Lab: https://www.augusta.edu/mcg/dnrm/faculty/blakelab.phpCortical acetylcholine response to deep brain stimulation of the basal forebrain - Brain Stimulation Jan/Feb 2025 (Open access full text)https://www.brainstimjrnl.com/article/S1935-861X(24)00979-3/fulltextIntermittent stimulation of the basal forebrain improves working memoryin aged nonhuman primates Jan/Feb 2025 (Abstract) https://www.brainstimjrnl.com/article/S1935-861X(24)00735-6/fulltextSynchron: https://synchron.comECoG (Electrocorticography): https://en.wikipedia.org/wiki/Electrocorticography#:~:text=Electrocorticography%20(ECoG)%2C%20a%20type,activity%20from%20the%20cerebral%20cortex.00:00 Introduction to the Neurostimulation Podcast01:11 Sponsor and Guest Introduction01:43 Deep Brain Stimulation Research Overview04:04 Discussion with Dr. David Blake06:27 Dr. Blake's Research and Findings22:10 Future Directions and Applications40:14 Brain-Computer Interfaces and Neuromodulation45:10 Advice for Aspiring Neuroscientists48:54 Conclusion and Farewell
Exploring Remote Neurostimulation in Multiple Sclerosis: A Conversation with Drs. Charvet and PilloniIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore from the University of British Columbia engages with Dr. Leigh Charvet and Dr. Giuseppina Pilloni, who break down their research on remotely supervised transcranial direct current stimulation (RS-tDCS). Their discussion focuses on the feasibility, safety, and real-world applications of home-based neurostimulation treatments for multiple sclerosis (MS), targeting symptoms like fatigue and hand dexterity. They also explore broader implications for the future of personalized and accessible neurorehabilitation and explain the mechanisms and potential of tDCS as a complementary treatment option, extending to areas like depression and addiction. The episode underscores the promise of integrating therapy into the home, providing valuable insights for clinicians, researchers, and individuals living with neurological disorders.NYU Langone Clinical tDCS Service Programhttps://nyulangone.org/care-services/tdcs-program?cid=sem_google&sem_campaign_id=22139905662&sem_ad_group_id=&sem_creative_id=&gad_source=1&gad_campaignid=22139906628&gbraid=0AAAAAC9qk2v7bAhjNaz7bDanP8kgj4JsH&gclid=CjwKCAjwo4rCBhAbEiwAxhJlCTSji-MZmNiT9pziGg86R4hb7Mst8JAEHawsJKYB3-vob28tdL4D0RoC2B0QAvD_BwEClinical Research Study: HRV-Guided tDCS: Integrating a Biomarker for Clinical Utility https://clinicaltrials.med.nyu.edu/clinicaltrial/2591/hrv-guided-tdcs-integrating-biomarker/Clinical Research Study: Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosishttps://clinicaltrials.gov/study/NCT06901687?cond=multiple%20sclerosis%20&intr=tDCS&rank=1NYU Langone’s Neuromodulation Lab https://med.nyu.edu/research/charvet-lab/Publications https://med.nyu.edu/research/charvet-lab/publications00:00 Introduction to the Neurostimulation Podcast02:06 Today's Episode: Remote Supervised tDCS for MS03:38 Meet the Experts: Dr. Charvet and Dr. Pilloni04:24 Dr. Charvet's Journey in Neurostimulation06:18 Dr. Pilloni's Background and Research08:30 The Importance of Remote Neurostimulation11:05 Study Design and Methodology13:11 Results and Implications of the Study21:18 Challenges and Future Directions26:50 Exploring Integrated Markers for Treatment Guidance28:12 The Role of Biomarkers in Depression Studies30:16 Mechanistic Studies and Brain Perfusion Insights33:01 Broad Activation and Neuroplasticity34:09 tDCS as a Complementary Treatment37:09 Challenges and Safety in Home-Based tDCS41:12 Accessibility and Future Directions44:57 Cannabis Use and Neurostimulation47:52 Closing Thoughts and Future Prospects51:12 Final Remarks and Podcast Wrap-Up
Neurostimulation Podcast: Self-Care for Caregivers with Jenny LytleWelcome to the Neurostimulation Podcast! In this episode, we explore the intersection of neuroscience, clinical neurostimulation, and self-care for caregivers. Host Michael welcomes Jenny Lytle, an experienced hospice nurse and author of 'Self-Care Isn't Selfish.' They discuss Jenny's journey to prioritizing self-care, her BECOMING method, and practical tips to avoid burnout. This episode is perfect for healthcare professionals, caregivers, and anyone interested in improving their mental and emotional well-being.https://www.selfcareisntselfish.com/00:00 Introduction to the Neurostimulation Podcast01:44 Meet Jenny Lytle: A Journey of Self-Discovery03:00 The Importance of Self-Care for Caregivers05:18 Balancing Caregiving and Self-Care12:01 The BECOMING Method: Personalized Self-Care18:13 Jenny's Book: Self-Care Isn't Selfish20:43 Personal Reflections and Lessons Learned24:54 Honoring a Loved One's Memory25:12 Balancing Caregiving and Self-Care26:11 Practical Self-Care Tips27:36 The Power of Gratitude29:47 Inspiration from Hospice Care32:08 Faith and Spirituality in Self-Care40:49 The Journey of Becoming45:48 Resources and Final Thoughts48:38 Podcast Conclusion
Deep Dive into Transcranial Direct Current Stimulation (tDCS)In this episode of the Neurostimulation podcast, Dr. Michael Passmore, clinical associate professor from the University of British Columbia, delves into the intricacies of Transcranial Direct Current Stimulation (tDCS). The discussion covers the basic mechanisms of tDCS, its applications in modulating brain function, and the biological underpinnings of its acute and long-term effects. Dr. Passmore explains how tDCS influences neuronal activity, neuroplasticity, and even the microarchitecture of brain tissue. The episode also explores the clinical implications of tDCS, the importance of personalized treatment, and future research directions aiming to improve the precision and effectiveness of this neuromodulation tool.00:00 Introduction to the Neurostimulation Podcast01:32 Exploring tDCS: Basics and Mechanisms03:28 Acute Effects of tDCS04:45 Long-term Effects and Neuroplasticity05:59 Beyond Neurons: Microarchitecture and Network Effects07:27 Personalized Treatment and Clinical Implications08:24 Future Directions and Conclusion09:44 Closing Remarks and Next Episode Teaser
Exploring Cutting-Edge Neurostimulation Techniques with Dr. David PlevinIn this episode of the Neurostimulation Podcast, Dr. Michael Passmore talks with Dr. David Plevin, an accomplished psychiatrist and PhD candidate at the University of Adelaide, about his pioneering work in clinical neurostimulation. They delve into various topics, including transcranial magnetic stimulation (TMS), theta burst TMS, and electroconvulsive therapy (ECT). Dr. Plevin sheds light on his systematic reviews and research on predictors of treatment response in depression, while also sharing his unique insights on addiction psychiatry and personalized medicine. The discussion expands to explore the potential applications of neurostimulation for substance use disorders and its future in both psychiatric and non-psychiatric treatments. Tune in for a thought-provoking conversation that promises both clinical insights and philosophical reflections on the future of brain-based therapies.https://researchers.adelaide.edu.au/profile/david.plevinDr. Plevin et al's Systematic Review https://www.sciencedirect.com/science/article/pii/S3050529124000849https://www.tmsjournal.org/article/S3050-5291(24)00084-9/pdfTrial comparing standard rTMS with TBS at 80% and 120% https://pubmed.ncbi.nlm.nih.gov/34332155/00:00 Introduction to the Neurostimulation Podcast00:34 Meet Dr. David Plevin02:28 The Journey to Psychiatry and Neurostimulation04:03 Personalized Medicine and TMS04:35 The Evolution of TMS and ECT06:02 Exploring Theta Burst Stimulation13:33 Predictors of TMS Response22:13 Combining TMS with Other Treatments35:46 Addiction Psychiatry and Neurostimulation45:07 The Future of TMS and Neurostimulation47:46 Conclusion and Farewell
Understanding Autism with Sam Mitchell: Breaking Stigmas and Advocating for Change | Neurostimulation PodcastJoin us on the Neurostimulation Podcast as host Michael Passmore talks with Sam Mitchell, the inspiring leader of Autism Rocks and Rolls, about breaking the stigma around autism. Diagnosed with autism at the age of four, Sam shares his journey, the motivation behind his platform, and his mission to prove that those on the autism spectrum are not broken and don't need to be fixed. They dive into how society can better support individuals with autism, the importance of structure and routine, and the power of community. Additionally, Sam discusses his podcast, his passion for wrestling, and his plans for the future. This episode is a must-watch for anyone interested in autism advocacy and the incredible potential of individuals on the spectrum.https://autismrocksandrolls.com/00:00 Introduction to the Neurostimulation Podcast01:08 Sponsor and Guest Introduction02:49 Sam Mitchell's Journey with Autism03:58 Understanding Autism Spectrum10:10 Challenges and Stereotypes22:03 Building Community and Advocacy29:47 Future Projects and Closing Remarks
Exploring tDCS: Unveiling the Power of Transcranial Direct Current StimulationWelcome to the Neurostimulation Podcast, hosted by Michael Passmore, clinical associate professor at the University of British Columbia. In this episode, we delve into the world of transcranial direct current stimulation (tDCS) as outlined in chapter two of the 'Practical Guide to Transcranial Direct Current Stimulation.' Learn about the biophysics behind tDCS, its non-invasive nature, and how it affects neuronal activity. We break down the intricate details of how tDCS works, its application, key parameters, and emerging technologies like HD tDCS. We also touch on its historical background, ongoing research, potential clinical applications, and its promising future in mental health, rehabilitation, and more. This episode provides a comprehensive guide for anyone interested in understanding the subtle power and extensive promise of tDCS.00:00 Introduction to the Neurostimulation Podcast02:05 Exploring Transcranial Direct Current Stimulation (tDCS)03:06 The Essence of tDCS: Simplicity with Subtle Power04:58 Understanding the Physics of Electrical Current Flow06:56 Neuronal Polarization and Plasticity08:49 Acutely vs. After Effects of tDCS11:40 Dosing tDCS: Key Parameters13:55 Modeling, Personalization, and HD tDCS15:17 Historical Roots of Electrical Stimulation16:34 Mechanistic Nuances and Open Questions17:41 Real World Potential and Clinical Applications19:21 Conclusion and Recap
Exploring Leadership and Mental Health in Healthcare with Dr. Jessica Tighe | Neurostimulation PodcastIn this episode of the Neurostimulation Podcast, Michael Passmore, a clinical associate professor in the Department of Psychiatry at the University of British Columbia, hosts Dr. Jessica Tighe. Dr. Tighe, an executive coach with a PhD in Psychology, shares her extensive expertise in coaching and leadership, especially in high-stress environments like healthcare. The episode delves into strategies for stress management, team cohesion, servant leadership, and the importance of self-care and mental health. Dr. Tighe also discusses the impact of childhood trauma on healthcare professionals and offers practical advice for fostering a healthy and effective work environment. Join us for this enlightening conversation packed with actionable insights and advice on improving organizational effectiveness and personal well-being.https://www.soulutionsforhealth.com/https://www.facebook.com/profile.php?id=100083854606821https://www.linkedin.com/in/jesseca-tighe-426623141/00:00 Introduction to the Neurostimulation Podcast01:31 Introducing Dr. Jessica Tighe03:05 Dr. Tighe's Journey and Expertise05:04 Challenges in Healthcare Leadership09:14 Balancing Work and Personal Life19:13 Effective Communication and Boundaries28:45 Building Cohesive Teams29:54 Managing Through Text vs. Meetings30:44 Creating Safe Spaces in Healthcare31:08 Leadership and Emotional Support33:11 Mental Health and Childhood Trauma34:20 Personal Growth and Coping Mechanisms42:29 Servant Leadership Defined48:59 Self-Care and Boundaries for Leaders53:01 Conclusion and Final Thoughts
Unraveling the Secrets of Elastin: Its Impact on Health and Aging with Douglas MulhallJoin host Michael Passmore in this episode of the Neurostimulation Podcast as he discusses the fascinating world of elastin with biotech entrepreneur and author Douglas Mulhall. They delve into the importance of elastin fiber in the human body, its role in various health conditions, and how it differs from collagen. Douglas highlights groundbreaking research in elastin therapies aimed at reversing arterial damage, healing wounds, and preventing calcification. This educational podcast aims to provide listeners with a comprehensive introduction to elastin and its critical functions in maintaining vitality and health. Note: This episode is for educational purposes only and not intended as medical advice.Douglas' latest book: https://www.amazon.ca/Discovering-Nature-Longevity-Restoring-targeting/dp/1738926737Douglas' first book: https://www.amazon.ca/Our-Molecular-Future-Nanotechnology-Intelligence/dp/157392992100:00 Introduction to the Neurostimulation Podcast01:34 Meet Douglas Mulhall: Biotech Entrepreneur and Author02:46 Understanding Elastin: A General Introduction05:41 The Role of Elastin in the Human Body13:00 Factors Affecting Elastin Degradation26:17 Innovative Treatments and Research on Elastin38:01 Conclusion and Final Thoughts