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The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.
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Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a throwback trial of dexamethasone in adults with acute bacterial meningitis. Here we go! Dexamethasone in Adults with Bacterial Meningitis (0:00 – 11:19).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the effects of mifepristone on glycemic control in adults with inadequately controlled type 2 diabetes and hypercortisolism. Here we go! Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment (0:00 – 10:24).Questions? Comments? Feedback? We’d love to hear from you! @roundstable ...
Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of infrequent zoledronate administration on vertebral fracture prevention in early postmenopausal women, and the efficacy and safety of semaglutide in adults with type 1 diabetes and obesity. Two papers, here we go! Fracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age (0:00 – 10:24)Semagl...
Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of bedtime vs morning administration of antihypertensive medications on major cardiovascular events and death. Here we go! Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial (0:00 – 5:18).The Good Stuff: Resources for trainees (5:19 - 6:20):Medicine Pods...
Send us a text Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024: Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabol...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28) Trainees, med ...
Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College podcast—to talk about leukocytoclastic vasculitis. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death. Here we go! Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death (0:00 – 5:38).The Good Stuff: 2025 Scripps National Spelling Bee winning word: éclaircissement (5:39 - 6:34)Q...
Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go! Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–...
Send us a text Welcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go! 1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (0:00 - 24:24) Access the KDIGO 2024 "Top 10 Takeaways" PDFs here: https://kdigo.org/guidelines/ckd-evaluation-and-manage...
Send us a text Welcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go! 1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08) 2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09...
Send us a text Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go! 1. Effect of Opioid vs Non...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published head-to-head trial exploring the safety and efficacy of tirzepatide compared to semaglutide for obesity management. Here we go! Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (0:00 – 7:07).The Good Stuff: Trial Files, a free monthly newsletter on practice-changing trials, delivered straight to your inbox. (7:08 - 7:53)Quest...
Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. David Juurlink, pharmacologist and internist, Professor of Medicine at the University of Toronto, and head of the Clinical Pharmacology and Toxicology division at Sunnybrook Health Sciences Centre, to chat about the top drug interactions you might be missing. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtW...
Send us a text Welcome back, Rounds Table Listeners! This week we have a solo episode with Dr. John Fralick, discussing a recently published trial of the GLP-1 receptor agonist semaglutide for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Here we go! Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis (0:00 – 6:33).The Good Stuff: Go Leafs go!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @Medicine...
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the safety and efficacy of lorundrostat (an aldosterone synthase inhibitor) in treatment of uncontrolled and treatment-resistant hypertension. Here we go! Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension (0:00 – 7:02).The Good Stuff: Trial Files, a free monthly newsletter on practice-changing tr...
Send us a text Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of brensocatib (a DPP-1 inhibitor) to treat bronchiectasis, and the effect of alteplase administered 4.5 to 24 hours after stroke in patients with mild posterior circulation stroke who did not receive thrombectomy. ...
Send us a text Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Clinical Practice Guidelines series. This week, Drs. Mike and John Fralick discuss the 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome. Here we go! 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes (0:00 - 18:56)Mike's interview with Dr. Jeff Carson: Episode 110 - Restrictive versus Liberal Transfusion in Myo...
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go! Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff: We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!&nb...
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thank you for discussing Oliver Sacks!!!