Episode 141 - Spironolactone in Patients on Maintenance Dialysis and Prophylactic Antibiotics for Upper GI Bleed in Cirrhosis
Update: 2025-11-06
Description
Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and antibiotic prophylaxis in patients with cirrhosis and upper gastrointestinal bleeding. Two papers, here we go!
- Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial (0:00 – 7:19 )
- Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis (7:20 – 15:08 )
And for the Good Stuff (15:09 – 17:51 ):
- The $500m slugger who helped Canada get to the World Series
- Clinical practice guidelines one-pagers coming soon to Trial Files: https://trialfiles.substack.com/
Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
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