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The Rounds Table
The Rounds Table
Author: Dr. John Fralick and Dr. Michael Fralick
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© 2025 The Rounds Table
Description
The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.
433 Episodes
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Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent systematic review and meta-analysis that looks at continuing versus withholding RAS inhibitors before noncardiac surgery. Here we go! Evaluating the risks and benefits of continuing versus withholding renin–angiotensin system inhibitors: a systematic review and meta-analysis with trial sequential analysis (0:00 – 8:20).The Good Stuff (8:21 – 9:44): NotebookL...
Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and antibiotic prophylaxis in patients with cirrhosis and upper gastrointestinal bleeding. Two papers, here we go! Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an interna...
Send us a text Welcome back Rounds Table Listeners! In this throwback episode (initial release 14 Mar 2024), Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two papers: one exploring the role of non-invasive ventilation in comatose patients after acute poisoning, and and one on the use of the PEN-FAST Score in the point-of-care risk assessment of penicillin allergy. Two papers, here we go! Effect of Noninvasive Airway Management of Comato...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent trial examining whether amiloride is noninferior to spironolactone in reducing systolic blood pressure in patients with resistant hypertension. Here we go! Spironolactone vs Amiloride for Resistant Hypertension: A Randomized Clinical Trial (0:00 – 8:10).Run-in studies: Application and impact of run-in studiesApplication and Impact of Run-In Studies for the E...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent phase 2 trial looking at the effects of once-weekly semaglutide on alcohol consumption and craving in adults with alcohol use disorder (AUD). Here we go! Once-Weekly Semaglutide in Adults With Alcohol Use Disorder (0:00 – 10:28).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
Send us a text Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick sits down with Mihir Pandya, a third-year medical student at Western University. Mihir picks Mike’s brain for advice on preparing for internal medicine clerkship: What’s the best approach to acquire knowledge on the varying conditions seen in internal medicine? How can you foster better rapport with patients? What’s the best way to ask your staff physician for a reference letter? Answers to these questions and mor...
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining fecal microbiota transplantation (FMT) in primary C. difficile infection. Here we go! Fecal Microbiota Transplantation Versus Vancomycin for Primary Clostridioides difficile Infection: A Randomized Controlled Trial (0:00 – 4:47).The Good Stuff (4:48 – 5:36): The I'm Pharmacy podcast, now featured on https://medicinepods.c...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial looking at aspirin in patients with chronic coronary syndrome receiving oral anticoagulation. Here we go! Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation (0:00 – 9:43).Throwback to EPIC-CAD: The Rounds Table Episode 94: Top Papers from the 2024 European Society of Cardiology Congress The Good Stu...
Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Drs. Mike and John Fralick discuss some of the top papers from the 2025 European Society of Cardiology (ESC) Congress. Hot off the presses, here we go! Increasing the Potassium Level in Patients at High Risk for Ventricular Arrhythmias (0:00 - 5:23)Digitoxin in Patients with Heart Failure and Reduced Ejection Fraction (5:24 - 10:23)RSV Prefusion F Vaccine for Prevention of Hospi...
Send us a text Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick sits down with Dr. Mina Tadrous, a pharmacist, researcher, Assistant Professor at the University of Toronto's Leslie Dan Faculty of Pharmacy, and host of the I'm Pharmacy podcast. If you're curious about what it takes to run a podcast, musings on the future of AI and drug discovery, and whether Mike can hold his own in a 90's-style rap battle, this is a conversation you don't want to miss. Here we go! Check out th...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a throwback trial of dexamethasone in adults with acute bacterial meningitis. Here we go! Dexamethasone in Adults with Bacterial Meningitis (0:00 – 11:19).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the effects of mifepristone on glycemic control in adults with inadequately controlled type 2 diabetes and hypercortisolism. Here we go! Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment (0:00 – 10:24).Questions? Comments? Feedback? We’d love to hear from you! @roundstable ...
Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of infrequent zoledronate administration on vertebral fracture prevention in early postmenopausal women, and the efficacy and safety of semaglutide in adults with type 1 diabetes and obesity. Two papers, here we go! Fracture Prevention with Infrequent Zoledronate in Women 50 to 60 Years of Age (0:00 – 10:24)Semagl...
Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of bedtime vs morning administration of antihypertensive medications on major cardiovascular events and death. Here we go! Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial (0:00 – 5:18).The Good Stuff: Resources for trainees (5:19 - 6:20):Medicine Pods...
Send us a text Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024: Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabol...
Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28) Trainees, med ...
Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College podcast—to talk about leukocytoclastic vasculitis. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death. Here we go! Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death (0:00 – 5:38).The Good Stuff: 2025 Scripps National Spelling Bee winning word: éclaircissement (5:39 - 6:34)Q...
Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go! Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–...




thank you for discussing Oliver Sacks!!!